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      • KCI등재

        Differential Prognostic Implications of Pre- and Post-Stent Fractional Flow Reserve in Patients Undergoing Percutaneous Coronary Intervention

        Jinlong Zhang,Doyeon Hwang,Seokhun Yang,Chee Hae Kim,Joo Myung Lee,Chang-Wook Nam,Eun-Seok Shin,Joon-Hyung Doh,Masahiro Hoshino,Rikuta Hamaya,Yoshihisa Kanaji,Tadashi Murai,Jun-Jie Zhang,Fei Ye,Xiaobo 대한심장학회 2022 Korean Circulation Journal Vol.52 No.1

        Background and Objectives: The influence of pre-intervention coronary physiologic status on outcomes post percutaneous coronary intervention (PCI) is not well known. We sought to investigate the prognostic implications of pre-PCI fractional flow reserve (FFR) combined with post-PCI FFR. Methods: A total of 1,479 PCI patients with pre-and post-PCI FFR data were analyzed. The patients were classified according to the median values of pre-PCI FFR (0.71) and post-PCI FFR (0.88). The primary outcome was target vessel failure (TVF) at 2 years. Results: The risk of TVF was higher in the low pre-PCI FFR group than in the high pre-PCI FFR group (hazard ratio, 1.82; 95% confidence interval, 1.15–2.87; p=0.011). In 4 group comparisons, the cumulative incidences of TVF at 2 years were 3.8%, 4.1%, 4.8%, and 10.2% in the high pre-/high post-, low pre-/high post-, high pre-/low post-, and low pre-/low post-PCI FFR groups, respectively. The risk of TVF was the highest in the low pre-/low post-PCI FFR group among the groups (p values for comparisons <0.05). In addition, the high pre-/low post-PCI FFR group presented a comparable risk of TVF with the high post-PCI FFR groups (p values for comparison >0.05). When the prognostic value of the post-PCI FFR was evaluated according to the pre-PCI FFR, the risk of TVF significantly decreased with an increase in post-PCI FFR in the low pre-PCI FFR group, but not in the high pre-PCI FFR group. Conclusions: Pre-PCI FFR was associated with clinical outcomes after PCI, and the prognostic value of post-PCI FFR differed according to the pre-PCI FFR.

      • KCI등재

        Circ_0000554 is identified as a cancer‑promoting circRNA in colorectal cancer by regulating the miR‑1205/LASP1 axis

        Luo Jinlong,Yang Hua,Peng Xuefeng,Zhang Faqiang,Shu Shilong,Lan Ke,Tu Shengjin,Lu Kai,Cha Xiaoying 한국응용생명화학회 2022 Applied Biological Chemistry (Appl Biol Chem) Vol.65 No.5

        Background: Colorectal cancer (CRC) is a prevalent malignant tumor with poor prognosis. Circular RNAs (circRNAs) are key regulators in the progression of CRC. Our study aimed to disclose the role of circ_0000554 in CRC. Methods: The expression of circ_0000554, miR-1205 and LIM and SH3 protein 1 (LASP1) was measured by quantitative real-time polymerase chain reaction (qRT-PCR). Cell proliferation, invasion and migration were monitored using cell counting kit-8 (CCK-8) assay, EdU assay, transwell assay and wound healing assay respectively. The protein levels of C-myc, matrix metallopeptidase 2 (MMP-2) and LASP1 were detected by western blot. Tumor formation assay in nude mice was conducted to explore the role of circ_0000554 in vivo. The association between miR-1205 and circ_0000554 or LASP1 was identified by dual-luciferase reporter assay and RNA immunoprecipitation (RIP) assay. Results: circ_0000554 was upregulated in CRC tissues and cells, high circ_0000554 expression was significantly linked to shorter overall survival. Downregulation of circ_0000554 restrained cell growth and metastasis while promoted apoptosis in vitro, and suppressed tumorigenesis of CRC in vivo. Furthermore, mechanism study and rescue experiments confirmed miR-1205 could be sponged by circ_0000554 and its inhibitor reversed the inhibitory effect of circ_0000554 silencing on CRC progression. LASP1 was a target gene of miR-1205 and the upregulation of LASP1 overturned miR-1205-induced effects on CRC cells. Circ_0000554 could elevate LASP1 expression via interacting with miR-1205.

      • KCI등재

        Metal organic frameworks template-directed fabrication of rod-like hollow BiOClxBr1x with adjustable band gap for excellent photocatalytic activity under visible light

        Ze Luo,Jinlong Li,Guozhe Sui,Yan Zhuang,Dongxuan Guo,Rongping Xu,Shuang Liang,Hong Yao,Chao Wang,Shijie Chen 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.8

        Developing an efficient, environmentally friendly, and pollution-free catalyst with excellent visible light catalyticactivity is a promising strategy for dye wastewater treatment. Herein, the rod-like hollow BiOClxBr1x (x=1, 0.75, 0.5,0.25, 0), with an adjustable band gap, was successfully prepared using Bi-based metal-organic framework as template. The corresponding hollow assembly and introduction of Br imparted valuable structural advantages and intrinsic characteristicsfor improved photocatalytic activity. Significantly, the degradation efficiency of BiOCl0.5Br0.5 for the RhodamineB (RhB) solution reached 92% under visible light illumination for 90 min, which is considerably higher than that ofCAU-17-derived Bi2O3 and BiOCl. Overall, these findings shed fundamental insight on constructing novel photocatalystswith excellent visible light driven photocatalytic activity and offered a new method for treating dye wastewater.

      • KCI등재

        Controllable Zn0.76Co0.24S Nanoflower Arrays Grown on Carbon Fiber Papers for High-Performance Supercapacitors

        Man Zhang,Yanwei Sui,Xiaofang Yuan,Jiqiu Qi,Fuxiang Wei,Qingkun Meng,Yezeng He,Yaojian Ren,Zhi Sun,Jinlong Liu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3

        A nanoflower structure of Zn0.76Co0.24S directly grown on carbon fiber papers (CFP) was successfully designed by a mild two-step hydrothermal method. Benefiting from their fascinating structural features, Zn0.76Co0.24S/CFP electrode exhibits a maximum specific capacitance of 300 F g -1 at current density of 1 A g -1 and 84% capacitance retention after 5,000 cycles at current density of 5 Ag -1. Subsequently, Zn0.76Co0.24S/CFP//AC all-solid-state asymmetric supercapacitor (ASC) device is assembled and able to illuminate the red LEDs. ASC devices deliver a maximum energy density of 9.59 Wh kg -1 at a power density of 750 W kg -1. Therefore, this impressive result demonstrates that the nanoflower Zn0.76Co0.24S have promising applications in the development of high-performance supercapacitors.

      • KCI등재

        Characterization of genes coding for galacturonosyltransferaselike (GATL) proteins in rice

        Shaobo Li,Jinlong Liu,Mansi Luo,Xin Yan,Chao Yu 한국유전학회 2016 Genes & Genomics Vol.38 No.10

        In the present study, seven galacturonosyltransferase- like (GATL) genes (OsGATLs) in rice (Oryza sativa L.) were genome-widely identified and the chromosomal locations and the gene structures of which were characterized. Under normal condition, OsGATL2 and OsGATL3 are highly expressed in root, while OsGATL4 is highly expressed in stem and leaf. Many cis-elements related to stress response and plant hormone were found in the promoter sequence of each OsGATL. The expression patterns of these OsGATL genes under treatment with abscisic acid (ABA), drought and low temperature were assessed by qRT-PCR. The expression levels of most OsGATLs significantly increased following the treatments with drought or low temperature. In addition, physicochemical properties of OsGATLs and phylogenetic analysis with GATL from rice and several other species were performed. 3D structures and protein–protein interaction (PPI) network of OsGATLs were further predicted by Swiss-model and STRING 9.0 database, respectively. The identification and bioinformatic analysis of GATL family in rice could provide reference data for further study on their biological functions, especially in the responsiveness to hormones and stress signaling.

      • KCI등재

        Physiologic Assessment after Coronary Stent Implantation

        Doyeon Hwang,Seokhun Yang,Jinlong Zhang,Bon-Kwon Koo 대한심장학회 2021 Korean Circulation Journal Vol.51 No.3

        The presence of myocardial ischemia is a prerequisite for the benefit of coronary revascularization. In the cardiac catheterization laboratory, fractional flow reserve and non-hyperemic pressure ratios are used to define the ischemia-causing coronary stenosis, and several randomized studies showed the benefit of physiology-guided coronary revascularization. However, physiology-guided revascularization does not necessarily guarantee the relief of ischemia. Recent studies reported that residual ischemia might exist in up to 15–20% of cases after angiographically successful percutaneous coronary intervention (PCI). Therefore, post-PCI physiologic assessment is necessary for judging the appropriateness of PCI, detecting the lesions that may benefit from additional PCI, and risk stratification after PCI. This review will focus on the current evidence for post-PCI physiologic assessment, how to interpret these findings, and the future perspectives of physiologic assessment after PCI.

      • KCI등재

        Interaction and Treatment for Tunnels Orthogonally Traversing Large Bedrock Landslides

        Changan Zhu,Feng Yang,Jinlong Zheng,Guojin Lin,Zhiyu Tian 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.7

        When a tunnel orthogonally traverses a large bedrock landslide, the interaction between the tunnel and the bedrock can easily disturb the stability of the slope and deformation of tunnel structures. In this work, Jimei tunnel in southwest China was studied as an example. The physical parameters of the landslide were inverted based on uniform design and a radial basis function neural network model and a model was established for the interaction of tunnel and bedrock landslide. Simulations showed that tunnel construction resulted in tensile failure at the trailing edge of bedrock landslide and clear deformation in the left line of the tunnel. This was consistent with the field damage observed in this work. A comparative analysis was performed of structural stability after the application of three schemes of earth-rock clearing, load-reducing, and slide-resistant pile arrangements. Optimal measures for landslide reinforcement were determined to ensure smooth tunnel construction and reduce project cost. Two years of continuous post-construction monitoring indicated that the stability of tunnel and landslide was preserved and treatment goal was achieved. Calculation methods and control measures developed in the current research for tunnels orthogonally traversing bedrock landslides provided a useful reference for similar projects in the future.

      • KCI등재

        Synthesis of thin diamond films from faceted nanosized crystallites

        Sobia Allah Rakha,Shumin Yang,Zhoutong He,Ishaq Ahmed,Dezhang Zhu,Jinlong Gong 한국물리학회 2009 Current Applied Physics Vol.9 No.3

        Diamond films consist of crystallites having nanometer grains were deposited using low methane concentration by hot filament chemical vapor deposition (HFCVD). The results show that films consist of nanodiamond grains with grain sizes ranging from 20 nm to 200 nm having thickness dependent size. Increasing the deposition time, the grain size increases and hence the hickness of the film increases. The diamond nucleation (nucleation density 1010 cm-2) is comparable to that obtained by biasing the substrate. The use of low methane concentration for the formation of nano crystallites improves the quality of the film as indicated by Raman spectroscopy. The distance between the filament and substrate is increased while maintaining the substrate temperature. The effects of this large separation on the gas phase chemistry are discussed which helps to understand the reduced size of the crystallites under input gas ratios when microcrystallines are obtained. Diamond films consist of crystallites having nanometer grains were deposited using low methane concentration by hot filament chemical vapor deposition (HFCVD). The results show that films consist of nanodiamond grains with grain sizes ranging from 20 nm to 200 nm having thickness dependent size. Increasing the deposition time, the grain size increases and hence the hickness of the film increases. The diamond nucleation (nucleation density 1010 cm-2) is comparable to that obtained by biasing the substrate. The use of low methane concentration for the formation of nano crystallites improves the quality of the film as indicated by Raman spectroscopy. The distance between the filament and substrate is increased while maintaining the substrate temperature. The effects of this large separation on the gas phase chemistry are discussed which helps to understand the reduced size of the crystallites under input gas ratios when microcrystallines are obtained.

      • KCI등재

        Novel Partitioning Algorithm for a Gaussian Inverse Wishart PHD Filter for Extended Target Tracking

        ( Peng Li ),( Hongwei Ge ),( Jinlong Yang ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.11

        Use of the Gaussian inverse Wishart PHD (GIW-PHD) filter has demonstrated promise as an approach to track an unknown number of extended targets. However, the partitioning approaches used in the GIW-PHD filter, such as distance partition with sub-partition (DP-SP), prediction partition (PP) and expectation maximization partition (EMP), fails to provided accurate partition results when targets are spaced closely together and performing maneuvers. In order to improve the performance of a GIW-PHD filter, this paper presents a cooperation partitioning (CP) algorithm to solve the partitioning issue when targets are spaced closely together. In the GIW-PHD filter, the DP-SP is insensitive to target maneuvers but sensitive to the differences in target sizes, while EMP is the opposite. The proposed CP algorithm is a fusion approach of DP-SP and EMP, which employs EMP as a sub-partition approach after DP. Therefore, the CP algorithm will be sensitive to neither target maneuvers nor differences in target sizes. The simulation results show that the use of the proposed CP algorithm will improve the performance of the GIW-PHD filter when targets are spaced closely together.

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