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Jinju Jeong,Chul Kim 대한화학회 2021 Bulletin of the Korean Chemical Society Vol.42 No.2
Flip-flop movement was investigated via dithionite assay of 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl)(ammonium salt) (NBD-PE) fluorescence in 1,2-dimyristoyl-sn-glycero-3-phosphocholine/1,2-dihexanoyl-sn-glycero-3-phosphocholine (DMPC/DHPC) vesicles with different DMPC/DHPC ratios. The activation energy was determined by using the Arrhenius plot and the thermodynamic functions were determined by the transition state theory. The activation energy increased upon addition of DHPC into the DMPC bilayer, but all the changes of the thermodynamic functions did not show a similar tendency. The experimental results suggest that the DHPC inserted in DMPC bilayers promote the flip-flop movement of NBD-PE in DMPC/DHPC vesicles by disordering the transition state by shorter DHPC molecule. This phenomenon might be related to the increment of the accessibility of water molecules into the ground state of the vesicle bilayer.
정진주(Jinju Jeong),반영환(Younghwan Pan) 한국디지털콘텐츠학회 2024 한국디지털콘텐츠학회논문지 Vol.25 No.3
Efficient and consistent designs are becoming increasingly essential. This study proposes a framework for building a sustainable interface design system for digital products using the cloud-based design tool Figma. Based on the atomic design methodology, we defined fundamental concepts of the design system and conducted literature reviews, case studies, and targeted group interviews for data collection to extract components of the design system and conceptualize a framework for its construction. The framework derived from the study extends the design system from a library of reusable components to a sustainable and collaborative ecosystem. The detailed process, presented in the form of a workflow, offers practical guidance for enhancing organizational workflow efficiency. The results warrant an exploration of potential applications, leading to future advancements in various organizations and companies.
So Jeong Kim,Jinju Lee,Woo Sun Choi,Hyo Jeong Kim,Mi-Yeon Kim,Sun Chang Kim,Hun Sik Kim 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.6
Background: Ginsenosides have beneficial effects on several airway inflammatory disorders primarilythrough glucocorticosteroid-like anti-inflammatory activity. Among inflammatory cells, eosinophils playa major pathogenic role in conferring a risk of severe refractory diseases including chronic rhinosinusitis(CRS). However, the role of ginsenosides in reducing eosinophilic inflammation and CRS pathogenesis isunexplored. Methods: We investigated the therapeutic efficacy and underlying mechanism of ginsenoside F1 (G-F1)in comparison with those of dexamethasone, a representative glucocorticosteroid, in a murine model ofCRS. The effects of G-F1 or dexamethasone on sinonasal abnormalities and infiltration of eosinophils andmast cells were evaluated by histological analyses. The changes in inflammatory cytokine levels insinonasal tissues, macrophages, and NK cells were assessed by qPCR, ELISA, and immunohistochemistry. Results: We found that G-F1 significantly attenuated eosinophilic inflammation, mast cell infiltration,epithelial hyperplasia, and mucosal thickening in the sinonasal mucosa of CRS mice. Moreover, G-F1reduced the expression of IL-4 and IL-13, as well as hematopoietic prostaglandin D synthase required forprostaglandin D2 production. This therapeutic efficacy was associated with increased NK cell function,without suppression of macrophage inflammatory responses. In comparison, dexamethasone potentlysuppressed macrophage activation. NK cell depletion nullified the therapeutic effects of G-F1, but notdexamethasone, in CRS mice, supporting a causal link between G-F1 and NK cell activity. Conclusion: Our results suggest that potentiating NK cell activity, for example with G-F1, is a promisingstrategy for resolving eosinophilic inflammation in CRS.
산화물계 촉매 적용을 통한 Li-CO₂ 전지 성능개선 연구
송정환(Jeong-hwan Song),서준교(Joon Kyo Seo),마지영(Jiyoung Ma),우중제(Jung-je Woo),송진주(Jinju Song),장일찬(Il Chan Jang) 한국전지학회 2023 한국전지학회지 Vol.3 No.2
Li-CO₂ battery performance is closely related to the formation of reaction products. Li₂CO₃ forms crystals at about 5 nm and MnO₂ is known to have a strong anchoring force with a Li-containing carbonaceous species. In this study, the performance of Li-CO₂ battery was improved by applying a 10wt% mesoporous Beta-MnO₂ catalyst by a hard template method using mesopore silica.