보건소를 이용하는 지역주민의 건강 행위와 건강관련 체력간의 관계

전미양,최명애,이인숙,김태수,김의숙,박선홍 대한보건협회 2002 대한보건연구 Vol.28 No.3

The purpose of this study is to identify relationship health behavior and health related physical fitness in order to provide the basic data for health promotion program for community people. The study was conducted 299 people, during the period from June 1, 2000 to October 30, 2000. The result are as follows. 1. Female comprised was 63.2%(189), while male comprised 36.8%(110). The age range of the subject were from 21 to 59 years old. The subject were aged 30s group 52.5%, 40s group 29.1%, 50s group 12.7%, 20s group 5.7%. Twenty subjects (6.7%) had experience smoking and one subject (0.3%) in female and nineteen subjects (6.4%) in male. Seventy-five subjects (25.1%) had experience drinking and twenty-nine subjects (9.7%) in female, and forty-six (15.4%) in male subjects. ninety-nine subjects had exercise and sixty subjects (20.1%) in female subjects and thirty-mine subject (13%) in male. 2. Body fat and flexibility were higher in female than male subjects, but cardioresperatory endurance, muscular strength and muscular endurance were higher in male than female subjects. 3. There were significant differences in body fat and muscular endurance between age group in both gender subjects, and in cardioresperatory endurance and muscular strength between the age group in male subjects. 4. No significant differences health related fitness between non-smoking and smoking group in both gender subjects. 5. No significant differences health related fitness between non-alcohol and alcohol group in both gender subjects. 6. For female subjects, muscular strength, muscular endurance and flexibility of the exercise group were significantly higher than those of the non exercise group. for male subjects, cardiorespiratory endurance of the exercise group were significantly higher than those of the non exercise group.

낙상예방 프로그램이 양로원 여성노인의 보행, 균형 및 근력에 미치는 영향

전미양,최명애 대한기초간호자연과학회 2002 Journal of korean biological nursing science Vol.4 No.1

Purpose:To determine the effect of the Fall Prevention Program(FPP) on gait, balance and muscle strength of elderly women at a nursing home. Methode:The subjects of this study consisted of 38 elderly women between the ages of 70 to 89 years living at a nursing home located in Seoul. Each of the experimental group and control group was composed of 19 subjects. The subjects in experimental group have participated in FPP for the 8 weeks which consisted of exercise, education and foot care. They started to exercise for 40 minutes per session, 3 sessions a week during the 1st week at 40% of age adjusted maximum heart rate. From the 2nd week to the 4th week, they increased the duration of exercise to 50 minutes per session and the intensity to 60% of age-adjusted maximum heart rate. They participated in 50 minutes at 60% of age-adjusted maximum heart rate from the 5th week to the 8th week. Each exercise session consisted of 10 minutes of warming-up exercise, 30 minutes of conditioning exercise and 10 minutes of cooling-down exercise. They participated in education for 20 minutes per week from the 1st week to the 4th week. Then they participated in a 30-minute foot care program per week from the 5th week to the 8th week. Gait, balance and muscle strength for each subject were measured before and after FPP. Gait was evaluated by step length, step width, gait speed and walking distance. Balance was measured by the duration of standing on one leg with their eyes closed and open each, and a get-up and go test. Grip strength was measured by hand dynamometer. Hip extensor and flexor strength, knee extensor and flexor strength and ankle plantarflexor and dorsiflexor strength were measured by manual muslce tester. Data was analyzed using SPSS from Windows. t-test and Chi square test were utilized as a homogeneity test. Repeated measure ANOVA was used to test the effect of FPP. Result:1) Step width significantly decreased, and step length, gait speed and walking distance significantly increased in the experimental group compared with the control group after FPP(p<.005). 2) There was no significant change in standing time on one leg with their eyes closed after FPP. The standing time on one leg with their eyes open and the time of “get-up and go” significantly decreased in the experimental group compared with the control group after FPP(p<.005). 3) Muscle strength-grip strength, hip extensor and flexor strength, knee extensor and flexor strength and ankle plantarflexor and dorsiflexor strength-significantly increased in the experimental group compared with the control group after FPP(p<.005). 4) There was no significant difference of frequency of fall between the experimental group and control group during the period of FPP. Conclusion:These results suggest that FPP can increase gait, balance and muscle strength of elderly women at a nursing home.

영지 (Ganoderma lucidum) 자실체 다당류의 분자량에 따른 생리활성

한만덕;김용현;이현수;권현정;전미애;한국일 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2

The study was conducted to investigate the biological activities of an protein-bound polysaccharide (GLP) isolated from the fruit body of Ganoderma lucidum. GLP was extracted by hot water and then it was purified high (GLP-HM) and low (GLP-LM) molecular weight fraction by ethanol precipitation. Both of GLP-HM and GLP-LM at doses of 20 mg/kg in vivo had the ability to inhibit the tumor growth of Sarcoma 180 tumor-bearing mice. Inhibition rates of tumor (%) were inhibited 60.6% and 38.7% by GLP-HM and GLP-LM, respectively. In assay of anti-complementary activity in vitro, the GLP-HM were higher than that of the GLP-LM polysaccharide. And also, the GLP-HM enhanced nitric oxide production of mouse bone marrow cells. When the GLP-HM was injected intraperitoneally in tumor-bearing mouse at doses of 20 mg/kg, the concentration of TNF-α in vivo was 140.9 pg/ml in the serum, 269.6 pg/ml in sarcoma tumor mass and 879.4 pg/ml in liver. This study shows that the high molecular polysaccharide from mushroom can enhance more the bioactivities than that of the low molecular polysaccharide.

Sex change scale and pattern of Tegillarca granosa (Bivalvia: Arcidae) in 2011-2012

Mi Ae Jeon,Hyejin Kim,Kayeon Ku,Jung Sick Lee 한국발생생물학회 2015 한국발생생물학회 학술발표대회 Vol.2015 No.9

The sex of bivalves is classified into gonochorism and hermaphroditism, and hermaphroditism is further divided into simultaneous, and sequential. Simultaneous hermaphroditism is the simultaneous release of eggs and sperm by one organism during the same season. Sequential hermaphrodites are either male or female for one or several annual cycles (Heller, 1993; Gosling 2004; Collin, 2013). T. granosa is a sequential hermaphroditic bivalve undergoing sex change (Lee et al., 2014). However, definitive conclusion on whether the scale and pattern of sex change of T. granosa is always consistent could not be made. Therefore, the objective of this study was to reconfirm sex change in T. granosa and consider the scale and pattern of sex change compared to the results of Lee et al. (2014). The total number of T. granosa used for sex change identification was 777 with a shell length (SL) between 25.1-35.0 (30.9±2.13) mm. For Tegillarca granosa, the scale of sex change during 2006-2007 was reported to be 15.1% (Lee et al., 2014). In this study, the overall scale of sex change in T. granosa was 37.6% during 2011-2012, which was approximately 2.5 times higher than that reported by Lee et al. (2014). In addition, the difference between the sex change ratio from females to males and that from males to females was 15.3% during the period of 2011-2012, which was similar to the finding of 15.0% during 2006-2007 (Lee et al., 2014). The sex change ratio of female→male : male→female was 1 : 3.42 during 2006-2007 reported by Lee et al. (2014). It was 1 : 1.57 during 2011-2012 in this study.

Effect of 4-week regular dance movement on the physiopsychological changes in young women

Jeon,Mi-Yang,CHOE,Myoung-Ae,Cho,Mi-Kyoung 서울대학교 간호대학 간호과학연구소 1996 간호학 논문집 Vol.10 No.1

4주간의 규칙적인 율동적 동작수행이 젊은 여성의 생리, 심리적 변화에 미치는 효과를 밝힐 목적으로 연구에 참여하기를 원하는 10명의 여대생을 대상으로 1주 3회 1일 30분 4주에 걸쳐 규칙적으로 율동적 동작을 수행하도록 하였다. 율동적 동작프로그램은 Herber의 동작지침을 토대로 머리에서 발끝까지 움직이는 동작이 되게 하였고 준비동작으로 시작하여 빠른 동작, 스트레칭동작, 원을 그려 마주보면서 실시하는 자유동작, 발레동작으로 구성되었다. 규칙적인 율동동작 수행적과 4주 수행후 생리적 변화로 체중, 사지둘레 및 근력, 안정시 혈압과 심박동수를 측정하였고 심리적 변화로 스트레스 반응을 측정하였으며, 4주간의 율동적 동작 수행후 주관적 느낌을 면담하여 어의반응을 분석한 결과 다음과 같은 결론을 얻었다. 4주간의 규칙적인 율동적 동작 수행 후 하퇴 둘레가 유의하게 증가하였고, 우울의 평균점수가 유의하게 감소하였으며, 율동적 동작에 대한 주관적 느낌의 어의 반응이 긍정적이었다. 이상의 결과로 보아 4주간의 규칙적인 율동적 동작 수행으로 하퇴둘레가 증가하고 우울이 감소되며, 율동적 동작에 대한 주관적 느낌의 어의 반응이 긍정적이다라고 할 수 있겠다.

Adoptive transfer of all-trans-retinal-induced regulatory T cells ameliorates experimental autoimmune arthritis in an interferon-gamma knockout model

Jeon, Eun-Joo,Yoon, Bo-Young,Lim, Jung-Yeon,Oh, Hye-Jwa,Park, Hyun-Sil,Park, Min-Jung,Lim, Mi-Ae,Park, Mi-Kyung,Kim, Kyung-Woon,Cho, Mi-La,Cho, Seok-Goo Informa Healthcare 2012 Autoimmunity Vol.45 No.6

<P>Maintaining an appropriate balance between subsets of CD4<SUP>+</SUP> helper T cells and T regulatory cells (Tregs) is a critical process in immune homeostasis and a protective mechanism against autoimmunity and inflammation. To identify the role of vitamin A-related compounds, we investigated the regulation of interleukin (IL)-17-producing helper T cells (Th17 cells) and Tregs treated with all-trans-retinal (retinal). CD4<SUP>+</SUP>T cells or total cells from the spleens of C57BL/6 mice were stimulated under Treg-polarizing (anti-CD3/CD28 and TGF-β) or Th17-polarizing (anti-CD3/CD28, TGF-β, and IL-6) conditions in the presence or absence of retinal. To analyze their suppressive abilities, retinal-induced Tregs or TGF-β-induced Tregs were co-cultured with responder T cells. Collagen-induced arthritis (CIA) was established in interferon (IFN)-γ knockout mice. On day 13, retinal-induced Tregs were adoptively transferred to mice with established CIA after second immunizations. Compared with TGF-β-induced Treg cells, retinal-induced Tregs showed increased Foxp3 expression and mediated stronger suppressive activity. Under Th17-polarizing conditions, retinal inhibited the production of IL-17 and increased the expression of Foxp3.Retinal-induced Tregs showed therapeutic effects in IFN-γ knockout CIA mice. Thus, we demonstrated that retinal reciprocally regulates Foxp3<SUP>+</SUP> Tregs and Th17 cells. These findings suggest that retinal, a vitamin A metabolite, can regulate the balance between pro- and anti-inflammatory immunity. A better understanding of the manipulation of Foxp3 and Tregs may enable the application of this tremendous therapeutic potential in various autoimmune diseases.</P>

Ecology and reproduction of the boring bivalve, Barnea davidi (Deshayes, 1874)

Mi Ae Jeon,Jung Sick Lee 한국발생생물학회 2013 한국발생생물학회 학술발표대회 Vol.2013 No.8

대학생의 인성특성과 지각된 진로장벽이 대학생활만족도에 미치는 영향

전미애(Jeon Mi Ae),김정모(Kim Jung Mo) 한국지역사회학회 2012 지역사회연구 Vol.20 No.1

The purpose of this study was to investigate the influence of university students1 personality characteristics and perceived career barriers on their campus life satisfaction. In this study, we have analyzed the subscale of campus-life satisfaction, personality characteristics and career barriers in the Yeungnam Aptitude Test(YAT) administered to more than 4, 500 freshmen. The results were as follows. Firstly, the campus life satisfaction was related to all personality characteristics and perceived career barriers. Secondly, the higher the personality characteristics (positivity, conscientiousness) and the less the career barriers (interpersonal competency, career identity, financial resources) were, the more the campus life satisfaction they showed. These findings suggest that the students life satisfaction would be facilitated by positive personality characteristic such as positivity, conscientiousness and the strengthening career identity.

분화된 3T3-L1 세포와 비만유도 쥐에 꽃송이버섯 추출물의 지질분해 효과

이미애(Mi-Ae Lee),박진경(Jin-Kyung Park),엄미향(Mi-Hyang Um),전정우(Jung-Woo Jeon),이정민(Jung-Min Lee),박유경(Yoo-Kyoung Park) 한국식품영양과학회 2012 한국식품영양과학회지 Vol.41 No.12

본 연구에서는 꽃송이버섯 추출물을 처리하여 분화된 3T3-L1 지방 세포와 비만 유도 쥐에서 지질분해 효과를 살펴보았다. In vitro, preadipocyte에서 MTT assay를 이용하여 세포독성 실험을 한 결과 시간, 농도에 관계없이 세포 생존율에 영향을 미치지 않았고, 분화된 지방세포에서의 지방분해 효과는 농도 의존적으로 감소되는 것을 확인할 수 있다. 이외에도 지방세포에서 지방분해 산물인 glycerol 양을 측정한 결과 48, 72시간에서 시간, 농도 의존적으로 유의성 있게 증가하였다. Lipolytic enzyme의 CPT-1 및 UCP-2 발현을 측정하기 위해 Western blot assay를 실시한 결과 꽃송이버섯 열수추출물이 CPT-1 및 UCP-2의 발현을 증가시키는 것을 확인할 수 있었다. In vivo에서 고지방 식이에 의해 비만이 유도된 쥐에 꽃송이버섯 열수추출물을 처리한 후 실험 종료 시 실험동물의 체중은 고지방식이를 공급한 군에 비해 저농도, 고농도 꽃송이버섯을 처리한 군 각각 유의적으로 감소하였다. 실험동물의 장기와 지방조직 무게를 측정한 결과, 대조군에 비해 추출물을 처리한 군에서 체중과 장기 및 지방조직의 감소가 저농도, 고농도 모두 유의하게 나타났으며, 혈청 및 간의 지질함량을 측정한 결과, 혈청지질의 중성지방, 총 콜레스테롤 함량 모두 대조군에 비해 유의적으로 낮게 나타났으며, HDL-콜레스테롤 함량은 유의적으로 높게 나타났다. 간의 지질함량을 측정한 결과 중성지방은 유의적으로 낮게 나타났고 총 콜레스테롤 역시 대조군에 비해 유의적으로 낮게 나타났다. 따라서 혈청 및 간의 지질함량을 측정한 결과 꽃송이버섯 열수추출물이 비만이 유도된 쥐의 혈청 및 간의 지질 농도 변화를 낮추는 효과가 있다고 사료된다. 따라서 꽃송이버섯 열수추출물은 lipolytic enzyme의 발현을 증가시켜 지방산의 산화 반응 및 열 발생에 의한 에너지 소비율을 증가시켜 lipid accumulation을 감소시키며, 이로 인한 체중 감소 및 혈청이나 간의 지질함량을 개선시켜 지질분해 효과를 보여줌으로써 비만 예방 및 치료를 목적으로 하는 식품 소재로서의 활용이 가능할 것으로 생각된다. The purpose of this study was to investigate whether water extracts of Sparassis crispa (SC) have anti-obesity effects. Treatment of mature adipocytes with SC caused a decrease in lipid accumulation (assessed by Oil Red O staining) and an increase in glycerol release. Mice were induced to obesity by a high fat diet (45% fat in total kcal) and experimental groups were treated with two different dosages of SC extracts, a low SC (LSC, 100 mg/kg/day) or high SC (HSC, 300 mg/kg/day). SC extracts were administered by gavages for 10 weeks in the experimental groups, while the control group was fed with distilled water. The body weight gain of mice fed SC was significantly reduced (11.88% lower in LSC, 14.54% lower in HSC) compared to the control group. Additionally, there were significantly reduced serum levels of triglycerides (13.57% lower in LSC, 19.46% lower in HSC), total cholesterol (32.22% lower in LSC, 24.67% lower in HSC) and glucose (28.85% lower in LSC, 25.82% lower in HSC) in mice fed SC compared to the control group. Hepatic triglycerides in mice fed SC were lower (9.68% lower in LSC, 14.24% lower in HSC) than the control group and total cholesterol levels were also lower in mice fed SC (38.72% lower in LSC, 35.20% in HSC). These results demonstrate that the water extract of SC may enhance lipolysis and up-regulate the expression of lipolytic enzymes in vitro and reduce body weight in vivo. These significant effects were found for both low and high doses of SC treatment, and suggest SC can be used as potential therapeutic substances for the prevention and treatment of obesity.

소목(Caesalpinia sappan L.)에서 분리한 Brazilin의 항산화 활성과 구강상피암 KB 세포주의 증식억제효과

전미애 ( Mi Ae Jeon ),권현정 ( Hyun Jung Kwon ),김용현 ( Yong Hyun Kim ),한국일 ( Kook Il Han ),정하나 ( Ha Na Chung ),정성균 ( Sung Kyun Chung ),방인석 ( In Seok Bang ),한만덕 ( Man Deuk Han ) 한국치위생과학회 2010 치위생과학회지 Vol.10 No.5