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이지전 ( Jee Jeon Yi ),김석일 ( Suck Il Kim ),유승흠 ( Seung Hum Yu ),이상옥 ( Sang Wook Yi ) 한국병원경영학회 2001 병원경영학회지 Vol.6 No.3
This study is about major symptoms of elderly and medical services for elderly in long-term care facilities. The subject of this study was 298 patients over 60 years old staying two geriatric hospitals and two nursing homes. The symptoms and medical services were level of patient classification from RUG(Resouce Utilization Group)-Ⅲ which is applied for both Medicare and Medicaid for skilled nursing facilities reimbursement system in US and designed for measuring patient characteristics and medical staff time. This classification is explained by each patient resource(staff time) utilization level which is called CMI(Case-Mix Index). In this study, the symptoms and services were compared by facility type and they were categorized by level and compared by CMI. Major findings are as follows; 1. There were more elderly who have cognitive function problems in nursing homes than patients in geriatric hospitals. There were more patients with behavioral problems in geriatric hospitals than residents in nursing homes. These results were both statistically significant. 2. The patients in geriatric hospitals received significantly more nursing rehabilitation services, rehabilitation services and extensive services than residents in nursing homes. Other hands, special care services were provided significantly more to residents in nursing homes than elderly in geriatric hospitals. 3. ADL and depression variables had higher CMI when the syptoms were heavier condition. The CMI were not matched with levels of cognitive function problems and behavioral problems. 4. The CMI matched well significantly with levels of nursing rehabilitation services, special care services, and clinically complex services provided for the patient in geriatric hospitals and only nursing rehabilitation services in nursing homes. The CMI for rehabilitation services level and extensive services had regular trends. From the result of this study, the resource utilization level and services provided for elderly in each long-term care facilities were figured out. For the further study, it needs to have more concern about RUG-Ⅲ which classification variables were just analyzed.
Clinical Characteristics of Patients with Smear-negative Pulmonary Tuberculosis
( Seung Hoon Kim ),( Ju Sang Kim ),( Hyung Woo Kim ),( Yong Hyun Kim ),( Sung Soo Jeong ),( Jee Youn Oh ),( Jin Woo Kim ),( Sang Haak Lee ),( Sung Kyoung Kim ),( Sun-hyung Kim ),( Jinsoo Min ) 대한결핵 및 호흡기학회 2023 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.136 No.0
Impact of illiteracy on depression symptomatology in community-dwelling older adults
Kim, Byung-Soo,Lee, Dong-Woo,Bae, Jae Nam,Chang, Sung Man,Kim, Shinkyum,Kim, Ki Woong,Rim, Hyo-Deog,Park, Jee Eun,Cho, Maeng Je Cambridge University Press 2014 INTERNATIONAL PSYCHOGERIATRICS - Vol.26 No.10
<B>Abstract</B><B>Background:</B><P>In many countries, illiteracy rates among aged people are quite high. However, only few studies have specifically investigated the impact of illiteracy on depression.</P><B>Methods:</B><P>Data for 1,890 elderly individuals (aged ≥65 years) were obtained from a nationwide dementia epidemiological study conducted in South Korea. Based on their reading ability, the participants were divided into three groups: totally illiterate, partially illiterate, and literate. The Korean version of the Geriatric Depression Scale - Short Form (SGDS-K) was used to detect depression (cut-off score = 8). Multivariate logistic regression analyses were used to assess the association between illiteracy and depression. To explore clinical features of depression in illiterate people, we performed logistic regression to calculate odds ratios of positive responses (or negative responses to reverse-coded items) for each SGDS-K item using literate individuals as the reference group.</P><B>Results:</B><P>Totally illiterate participants had 2.41 times the odds and partially illiterate individuals had 1.59 times the odds of being depressed compared with literate participants after controlling for other variables. Compared with literate individuals, illiterate elderly persons were at increased odds for responding negatively to the majority of SGDS-K items, including “having memory problems,” “others are better off than me,” and “feeling worthless” even after controlling for various demographic and clinical factors.</P><B>Conclusions:</B><P>Illiteracy in elderly individuals was associated with a higher rate and increased severity of depression. Illiteracy negatively affected depression symptomatology, especially factors associated with self-esteem. Therefore, clinicians should carefully monitor for the presence of depression in illiterate elderly adults.</P>
Irbesartan prevents myocardial remodeling in experimental thyrotoxic cardiomyopathy.
Kim, Bo Hyun,Cho, Kyoung Im,Kim, Seong Man,Kim, Jee-Yeon,Choi, Bo Gwang,Kang, Ji Hyun,Jeon, Yun Kyung,Kim, Sang Soo,Kim, Seong-Jang,Kim, Yong Ki,Kim, In Joo Japan Endocrine Society 2012 Endocrine journal Vol.59 No.10
<P>This study evaluated the effects of irbesartan and propranolol on thyroid hormone (TH)-induced cardiac functional and structural remodeling. A rat model of thyrotoxicosis was established by daily intraperitoneal injections of L-thyroxine (T(4), 100 μg/kg) for 4 weeks. Forty Sprague-Dawley rats were randomly divided into four groups (n = 10 each): control group, T(4) group (T(4) alone), T(4) plus irbesartan group (T(4)-Irb, 30 mg/kg), and T(4) plus propranolol group (T(4)-Pro, 0.5mg/mL of drinking water). Cardiac chamber size and functional parameters were measured by echocardiography and cardiomyocyte diameter. Heart rate (HR) and cardiac fibrosis were determined. T(4) alone showed significantly increased HR and cardiomyocyte width (25.0 1.77 vs. 18.8 0.84 μm, P < 0.001) with fibrosis, reduced left ventricle (LV) longitudinal strain (S(long); -16.0 6.27 vs. -22.7 5.19 %, P < 0.001) compared with control. When compared with T(4) alone, T(4)-Irb showed significantly improved LV S(long) (-21.4 1.84 vs. -16.0 6.27 %, P =0.017) and reduced cardiomyocyte width (21.0 1.0 vs. 25.0 1.77 μm, P =0.002) with comparable HR (458.4 24.3 vs. 486.6 30.1 bpm, P = 0.086). However, T(4)-Pro showed significantly reduced HR with improved LV S(long) without alteration of cardiomyocyte width and fibrosis compared with T(4) alone. In conclusion, renin-angiotensin system (RAS) blocking by irbesartan could significantly attenuate TH-induced cardiac structural and functional remodeling. However, HR reduction by propranolol could not alternate structural remodeling, which may implicate the RAS as having an important role in thyrotoxic cardiomyopathy beyond tachycardia.</P>
A Case of Successful Management of Lung Cancer Pain Using Ultrahigh-dose Fentanyl Patch
Kim, Soo-Ok,Kim, Min-Jee,Kwon, Yong-Soo,Lim, Sung-Chul,Ban, Hee-Jung,Oh, In-Jae,Kim, Kyu-Sik,Kim, Young-Chul The Korean Academy of Tuberculosis and Respiratory 2010 Tuberculosis and Respiratory Diseases Vol.68 No.5
A 55-year old woman with advanced stage non-small cell lung cancer was admitted to hospital for the management of severe chest pain, which measured 7 out of 10 on a numerical rating scale (NRS). Despite palliative radiation and the application of multiple epidural blocks, she continued to experience severe cancer pain. We gradually increased the dose of transdermal fentanyl patches from $500{\mu}g/hr$ to $3,650{\mu}g/hr$, for 3 months without any significant side effects. Concomitantly, adjuvant therapy with antidepressants and anticonvulsants were added, decreasing the patient's pain to NRS 3~4 down from 7. After being transferred to a hospice clinic, her chest pain was well-controlled below NRS 4 by means of strong opioid medications, including the highest dose of transdermal fentanyl $4,050{\mu}g/hr$ for more than 16 months.
Kim, Yonggoo,Yang, Chul Woo,Moon, In-Sung,Kim, Myungshin,Lim, Jihyang,Park, Yeon-Joon,Han, Kyungja,Oh, Eun-Jee Institute for Clinical Science] 2010 Annals of clinical and laboratory science Vol.40 No.4
<P>Development of a solid-phase, single antigen panel reactive antibody test (SA-PRA) permits the analysis of antibody specificities. This study determined the impact of donor-specific antibodies (DSA) against class I HLA private antigens (DS-HLA) or HLA-A and -B cross-reactive group (DS-CREG) in kidney transplantation. Pre- and post-transplant sera of 133 renal allograft patients who had negative pretransplant complement-dependent cytotoxicity were tested for HLA class I antibody specificities by SA-PRA. Clinical relevance of the flow cytometric crossmatch test (FCXM) for the detection of class I DS-HLA or DS-CREG was analyzed. The sensitivity of FCXM to detect SA-PRA-defined class I DSA was 50% (5/10) and the specificity was 98.4% (121/123). Of 133 renal allograft recipients, including 26 patients with biopsy-proven acute antibody-mediated rejection (AMR), pretransplant DS-HLA or DS-CREG were detected in 10 patients. Pretransplant DSA were associated with AMR (p = 0.012) and a low calculated glomerular filtration rate (p = 0.036). In the analysis of post-transplant sera, the presence of either type of HLA antibodies and the de novo development of DSA were correlated with AMR (p <0.001). This study demonstrates that detection of DSA, including DS-HLA and DS-CREG, using the SA-PRA assay is useful to identify the renal allograft recipients with poor transplant outcome.</P>
Minimization of diauxic growth lag-phase for high-efficiency biogas production
Kim, Min Jee,Kim, Sang Hun Academic Press 2017 Journal of Environmental Management Vol. No.
<P>The objective of this study was to develop a minimization method of a diauxic growth lag-phase for the biogas production from agricultural by-products (ABPs). Specifically, the effects of proximate composition on the biogas production and degradation rates of the ABPs were investigated, and a new method based on proximate composition combinations was developed to minimize the diauxic growth lag-phase. Experiments were performed using biogas potential tests at a substrate loading of 2.5 g VS/L and feed to microorganism ratio (FPM) of 0.5 under the mesophilic condition. The ABPs were classified based on proximate composition (carbohydrate, protein, and fat etc.). The biogas production patterns, lag phase, and times taken for 90% biogas production (T90) were used for the evaluation of the biogas production with biochemical methane potential (BMP) test. The high- or medium-carbohydrate and low-fat ABPs (cheese whey, cabbage, and skim milk) showed a single step digestion process and low-carbohydrate and high-fat ABPs (bean curd and perilla seed) showed a two-step digestion process. The mixture of high-fat ABPs and high-carbohydrate ABPs reduced the lag-phase and increased the biogas yield more than that from single ABP by 35-46%. (C) 2016 Elsevier Ltd. All rights reserved.</P>
Sarcopenia and Age-Related Changes in Body Composition in Korean Older Persons
Jee-Aee Im,Sang-Hwan Kim,Hee-jung Lim,Chang-hee Kim,Sang-Hoon Suh 대한의생명과학회 2008 Biomedical Science Letters Vol.14 No.1
We examined the prevalence of sarcopenia and age-related changes in body composition in Korean older persons. Community dwelling 77 men and 65 women (60~88 yr) were recruited for this study. Fat-free mass and the percent body fat were determined using bioelectrical impedance analysis. Isometric grip strength was measurement using grip strength dynamometer. Serum levels of fasting glucose, total cholesterol, HDL-cholesterol, and triglyceride were assayed. The prevalence of sarcopenia was found to increase with aging (men in their sixties 82.6%, seventies 96.6% and eighties 100%, and women in their sixties 47.4%, seventies 63%). In both gender groups, handgrip strength was inversely correlated with age and positively correlated with height, lean mass, and fat free mass. Better handgrip strength was related with higher weight in the men and with lower heart rate in the women. Fat free mass, age, and gender were found to be independent factors significantly associated with handgrip strength in the multivariate analysis. In summary, results of the present study suggest that handgrip strength is well associated with age, gender, and fat free mass and the prevalence of sarcopenia is increased with age and is exceeded by 40% among Korean persons older than 60 years.