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Yeon-Jung Lim,Ha-Yeon Kim,Jaekyung Choi,Ji Sun Lee,Ah-Leum Ahn,Eun-Jung Oh,Dong-Yung Cho,Hyuk-Jung Kweon 대한가정의학회 2016 Korean Journal of Family Medicine Vol.37 No.6
Background: Prescription of inappropriate medicine to elderly patients is a major public health care concern. The Beers criteria have been commonly employed as a screening tool to identify the use of potentially inappropriate medications (PIMs). The present study investigated the prevalence of PIM use according to the Beers criteria as well as factors related to PIM use.Methods: Data obtained from a retrospective survey included 25,810 outpatients aged ≥65 years from a university medical center in Seoul, Korea. PIMs were defined using the Beers criteria. Factors associated with PIM use were evaluated using multiple regression analysis.Results: Of all participants, 7,132 (27.6%) were prescribed at least one PIM. The most commonly prescribed PIMs were alprazolam (11.2%), clonazepam (10.8%), zolpidem (8.7%), quetiapine (8.4%), and hydroxyzine (5.4%). In multivariate logistic regression analysis, having five or more prescription medicines (odds ratio [OR], 11.32; 95% confidence interval [CI], 9.38 to 13.66) and five or more prescribing doctors (OR, 4.40; 95% CI, 3.59 to 5.39) were strongly associated with PIM. In a likelihood ratio test for trend, an increasing number of medications and prescrib-ing doctors were both significantly associated with PIM.Conclusion: At a university medical center, the number of medications and the number of prescribing doctors was associated with PIM in older outpatients.
정성인(Sungin Jung),정재열(Jaeyeol Jung),김정녀(Jungneo Kim),이재경(Jaekyung Lee),하상용(Sangyoung Ha),여인석(Inseok Yeo),남궁한(Han Namgoong),손덕주(Dukjoo son),임기욱(Keewook Rim) 한국정보과학회 1993 한국정보과학회 학술발표논문집 Vol.20 No.2
메모리 관리는 주 기억장치 자원과 프로세스의 주소공간 관리를 주요한 기능으로 하는 운영체제 커널의 한 부분이다. 여러 단체의 표준화에 부합되며 높은 유연성과 이식성을 갖는 UNIX SVR4 i386/486 MP V2(이하 SVR4 MP)는 고속 중형 컴퓨터의 운영체제로 사용한다. 이 운영체제로 고속 중형 컴퓨터의 처리기 종속 부분과 시스템 형상 종속 부분을 분석하여 목표 시스템의 운영체제로 재설계 한다. 본 논문은 소형 시스템용으로 설계된 SVR4 MP를 중형 시스템의 고속 중형 컴퓨터에 맞도록 시스템 형상 종속 부분을 추출하여 재설계한 내용을 소개한다.
( Jaekyung Bae ),( Ji-Hyung Yoon ),( Jung-hee Lee ),( Jong-ho Nam ),( Chan-hee Lee ),( Jang-won Son ),( Ung Kim ),( Jong-seon Park ),( Dong-gu Shin ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.6
Background/Aims: The clinical benefit of strict blood glucose-lowering therapy for patients with coronary artery disease (CAD) is still debated. We aimed to evaluate the long-term outcomes of patients with diabetes who under-went percutaneous coronary intervention (PCI), according to the mean hemoglobin A1c (HbA1c) level after PCI. Methods: We evaluated 675 diabetes patients with CAD treated with PCI. We categorized the study population into three groups based on the mean observed HbA1c levels during the follow-up duration, as follows: aggressive control (AC) group (HbA1c level < 6.5%, n = 148), moderate control (MC) group (HbA1c level ≥ 6.5% and < 7.0%, n = 138), and uncontrolled (UC) group (HbA1c level ≥ 7.0%, n = 389). The primary endpoint was major adverse cardiovascular and cerebrovascular events (MACCEs), defined as cardiac death, myocardial infarction, repeat target vessel revascularization, and stroke. Results: The mean HbA1c level of the AC group was significantly lower than that of the MC and UC groups (6.04% ± 0.36% vs. 6.74% ± 0.14% vs. 8.39% ± 1.20%, p < 0.001). The incidence of MACCEs was significantly lower in the AC group than in the MC and UC groups (16.0% vs. 24.3% vs. 26.3%, p = 0.010), mostly driven by the incidence of stroke (4.4% vs. 14.0% vs. 11.4%, p = 0.013). Multivariate Cox regression analysis showed that only the AC group was associated with a reduced rate of MACCEs (hazard ratio, 0.499; 95% confidence interval, 0.316 to 0.786; p = 0.004) com-pared with the UC group. Conclusions: Our study showed that intensive glycemic control (HbA1c level < 6.5%) is associated with improved clinical outcomes after PCI in patients with diabetes.