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Sang Mi Ro1,Sung Ho Her,Sol Mi Huo,Kuhn Park,Jong Bum Kwon,Dong Jae Lee,Hyun Jin Noh 조선대학교 의학연구원 2015 The Medical Journal of Chosun University Vol.40 No.3
Left ventricular (LV) thrombi may be caused by various conditions, particularly myocardial infarction. In most cases, LV thrombus occurs in patients with a significantly reduced ejection fraction. A LV thrombus is extremely rare in patients with normal LV function. We report a case of LV thrombus initially detected on transthoracic echocardiography and confirmed using cardiac magnetic resonance imaging in a patient with normal LV wall motion. We highlight the rarity of this condition and the usefulness of cardiac magnetic resonance imaging in the diagnosis of LV thrombus.
( Sung Min Kim ),( Jong Baik Kim ),( Hoo Min Choi ),( Jae Won Kang ),( Byung In Ro ),( Han Kyoung Cho ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Hobnail hemangioma, also known as targetoid hemosiderotic hemangioma, benign vascular tumor, characterized histologically by a biphasic growth pattern of dilated vascular structures in the superficial dermis lined by prominent hobnail endothelial cells, and collagen dissecting, rather narrow neoplastic vessels in deeper parts of the lesion. The lesion has a characteristic ‘targetoid’ appearance, in which violaceous papule is usually surrounded by thin, pale rim with peripheral ecchymotic halo, occurring commonly on the trunk and extremities. A 12-year-old male patient visited our hospital with a 3mm sized, well-demarcated violaceous, irregularly bordered papule with ecchymotic halo on right chest that appeared 3 years ago. A 3mm skin biopsy was performed from the lesion to rule out granuloma pyogenicum, patch stage of Kaposi‘s sarcoma. Histologic examination showed dilated vascular channels with hobnail endothelial cells protruding into the lumen and occasional intraluminal papillary projections in the upper dermis. Deeper in the dermis, the vascular channels were thinner and seemed to dissect the collagen bundles. Other findings included numerous extravasated erythrocytes and mild perivascular lymphocyte infiltrates. In correlation with clinical findings, we diagnosed it as a hobnail hemangioma. The lesion disappeared completely following punch biopsy.
A case of generalized bullous fixed drug eruption
( Sung Min Kim ),( Jong Baik Kim ),( Hoo Min Choi ),( Jae Won Kang ),( Byung In Ro ),( Han Kyoung Cho ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Generalized bullous fixed drug eruption is bullous type of fixed drug eruption characterized by defined bullae at the same site following administration of medication. It is characterized by multiple, sharply defined, red macules and blisters of various sizes, bilaterally often in symmetric distribution. It occurs abruptly within a few hours to days following exposure to offending drug or sometimes the drug of similar group. Common medications that cause generalized bullous fixed drug eruption are antibiotics such as tetracycline, penicillin, quinolones and dapsone. A 76-year-old female patient visited our hospital with well-defined multiple erythematous patches and bullae on nearly whole body that appeared 5 hours ago after taking a second-generation cephalosporin used for periodontitis. Other mucosal invasion was not found. She visited our hospital 3 years ago with well-defined erythema without bullae on same with as the current one after taking cephalosporin. At the time of the biopsy, there was a favorable findings of fixed drug eruption. After stopping all other medications, we treated the patient with daily foam dressing and started methylprednisolone 60 mg a day and subsequently tapered once the lesions started healing. After 2 weeks, the lesions gradually recovered.
Case Report : Melanosis Ilei Associated with Chronic Ingestion of Oral Iron
( Jae Myung Cha ),( Joung Il Lee ),( Kwang Ro Joo ),( Sung Won Jung ),( Hyun Phil Shin ) The Editorial Office of Gut and Liver 2009 Gut and Liver Vol.3 No.4
Melanosis can affect various parts of the gastrointestinal tract. Melanosis of the colon is not uncommon, while melanosis of the ileum is extremely rare. We report a case of melanosis ilei associated with chronic ingestion of oral iron (256 mg of ferrous sulfate once or twice daily for approximately 5 years) in a 32-year-old woman with end-stage renal disease. The findings of a colonoscopy, which was performed as a part of her medical checkup, were normal up to the cecum; however, numerous brownish-black punctuate pigmentations of the ileal mucosa were observed. Microscopic examination revealed hemosiderosis in the lamina propria of the ileal mucosa, particularly at the tips of villi. The diagnosis of melanosis (hemosiderosis) ilei was made based on the endoscopic and histological findings. (Gut and Liver 2009;3:315-317)