Application of Decision Tree for the Classification of Antimicrobial Peptide

Lee, Su Yeon,Kim, Sunkyu,Kim, Sukwon S.,Cha, Seon Jeong,Kwon, Young Keun,Moon, Byung-Ro,Lee, Byeong Jae Korea Genome Organization 2004 Genomics & informatics Vol.2 No.3

The purpose of this study was to investigate the use of decision tree for the classification of antimicrobial peptides. The classification was based on the activities of known antimicrobial peptides against common microbes including Escherichia coli and Staphylococcus aureus. A feature selection was employed to select an effective subset of features from available attribute sets. Sequential applications of decision tree with 17 nodes with 9 leaves and 13 nodes with 7 leaves provided the classification rates of $76.74\%$ and $74.66\%$ against E. coli and S. aureus, respectively. Angle subtended by positively charged face and the positive charge commonly gave higher accuracies in both E. coli and S. aureusdatasets. In this study, we describe a successful application of decision tree that provides the understanding of the effects of physicochemical characteristics of peptides on bacterial membrane.

[Devices] Small-Signal Modeling of Gate-All-Around (GAA) Junctionless (JL) MOSFETs for Sub-millimeter Wave Applications

Jae Sung Lee,Seongjae Cho,Byung-Gook Park,James S. Harris,In Man Kang 대한전자공학회 2012 Journal of semiconductor technology and science Vol.12 No.2

In this paper, we present the radiofrequency (RF) modeling for gate-all-around (GAA) junctionless (JL) MOSFETs with 30-㎚ channel length. The presented non-quasi-static (NQS) model has included the gate-bias-dependent components of the source and drain (S/D) resistances. RF characteristics of GAA junctionless MOSFETs have been obtained by 3-dimensional (3D) device simulation up to 1 ㎔. The modeling results were verified under bias conditions of linear region (VGS = 1 V, VDS = 0.5 V) and saturation region (VGS = VDS = 1 V). Under these conditions, the root-mean-square (RMS) modeling error of Y₂₂-parameters was calculated to be below 2.4%, which was reduced from a previous NQS modeling error of 10.2%.

Small-Signal Modeling of Gate-All-Around (GAA) Junctionless (JL) MOSFETs for Sub-millimeter Wave Applications

Lee, Jae-Sung,Cho, Seong-Jae,Park, Byung-Gook,Harris, James S. Jr.,Kang, In-Man The Institute of Electronics and Information Engin 2012 Journal of semiconductor technology and science Vol.12 No.2

In this paper, we present the radio-frequency (RF) modeling for gate-all-around (GAA) junctionless (JL) MOSFETs with 30-nm channel length. The presented non-quasi-static (NQS) model has included the gate-bias-dependent components of the source and drain (S/D) resistances. RF characteristics of GAA junctionless MOSFETs have been obtained by 3-dimensional (3D) device simulation up to 1 THz. The modeling results were verified under bias conditions of linear region (VGS = 1 V, VDS = 0.5 V) and saturation region (VGS = VDS = 1 V). Under these conditions, the root-mean-square (RMS) modeling error of $Y_{22}$-parameters was calculated to be below 2.4%, which was reduced from a previous NQS modeling error of 10.2%.

Preparation and Application of an s-Triazine-Based Novel N-Halamine Biocide for Antimicrobial Fibers

Lee, Jae-Woong,Broughton, Royall M.,Akdag, Akin,Worley, S.D.,Huang, Tung S. The Korean Fiber Society 2007 Fibers and polymers Vol.8 No.2

N-halamines serve as important antimicrobial agents. Development of this class of compounds has been shown to provide benefits especially from a biocidal point of view. A novel s-triazine-based N-heterocycle, dichloro-m-aminophenylhydantoinyl-s-triazine (DAPHT), which could be rendered antimicrobial through exposure to diluted chlorine bleach; was synthesized and characterized by $^1H\;NMR$, $^{13}C$ NMR, and FT-IR. A finishing method was used to apply the N-halamine precursor onto cotton fabric, and the optimum conditions for finishing were investigated. The DAPHT-treated cotton fabric had durable antimicrobial properties up to 50 standard washing cycles and was rechargeable under normal laundry/bleaching conditions. The antimicrobial efficacy against Gram-positive and Gram-negative bacteria was demonstrated.

A 21 cm SPECTRAL AND CONTINUUM STUDY OF IC 443 USING THE VERY LARGE ARRAY AND THE ARECIBO TELESCOPE

Lee, Jae-Joon,Koo, Bon-Chul,Yun, Min S.,Stanimirović,, Snež,ana,Heiles, Carl,Heyer, Mark American Institute of Physics 2008 The Astronomical journal Vol.135 No.3

<P>We report 21 cm spectral-line and continuum observations of the Galactic supernova remnant IC 443 using the Very Large Array (VLA) and the Arecibo telescope. By combining the VLA and Arecibo data, both covering the full extent of IC 443, we have achieved an unprecedented combination of sensitivity and angular resolution, over the continuous range of angular scales from ~40'' to ~1°. Our new radio observations not only reveal previously unknown features of IC 443 but also show the details of the remnant more clearly. The radio morphology of IC 443 consists of two nearly concentric shells. Our 21 cm radio continuum data show that the two shells have distinctly different radial intensity distributions. This morphology supports the scenario whereby the western shell is a breakout portion of the remnant into a rarefied medium. We have developed a dynamical model accounting for the breakout, which provides an estimate for the remnant age of ~2 × 10<SUP>4</SUP> yr. The southeastern boundary of the remnant shows interesting features, seen in our observations for the first time: a faint radio continuum halo and numerous 'spurs.' These features are mainly found in the region where IC 443 overlaps with another remnant, G189.6+3.3. These features most likely originate from the interactions of IC 443 with the surrounding medium. The H <SPAN CLASS='sml'>I</SPAN> emission associated with IC 443 appears over the velocity range between −100 km s<SUP>−1</SUP> and 50 km s<SUP>−1</SUP>. The strongest absorption is seen around v<SUB>LSR</SUB> ~ −5 km s<SUP>−1</SUP>, which corresponds to the systemic velocity of IC 443. We identify a broad, extended lane of H <SPAN CLASS='sml'>I</SPAN> gas near the systemic velocity as preshock gas in the southern part of the remnant. Most of the shocked H <SPAN CLASS='sml'>I</SPAN> gas is located along the southern supernova remnant (SNR) boundary and is blueshifted. We derive an accurate mass of the shocked H <SPAN CLASS='sml'>I</SPAN> gas using template HCO<SUP>+</SUP> (1-0) spectra, which is 493 ± 56 M<SUB>☉</SUB>. Our high-resolution H <SPAN CLASS='sml'>I</SPAN> data enable us to resolve the shocked H <SPAN CLASS='sml'>I</SPAN> in the northeastern region into a few filamentary structures, which are well correlated with radiative filaments, in both position and velocity. This represents the first unambiguous detection of the recombined H <SPAN CLASS='sml'>I</SPAN> in an atomic shock. The characteristics of the filaments are not consistent with a clumpy shock model where the radiative signature is from dense clumps. Instead we propose that the shock has been propagating through a uniform medium of n<SUB>H</SUB> ~ 10 cm<SUP>−3</SUP>.</P>

5축 CO₂ 레이저 컷팅 머신 및 CAM 시스템 개발

강재관(Jae-Gwan Kang),염경섭(G. S. Yeom),강병수(B. S. Kang),이홍주(H. J. Lee) 한국정밀공학회 2006 한국정밀공학회 학술발표대회 논문집 Vol.2006 No.5월

For developing 5-axis laser cutting systems, many problems such as rotating of laser head or table, 5-axis tool path generation and collision avoidance between laser head and product should be solved. In this paper, a five-axis laser cutting machine with table swivel and rotary type configuration is developed. The five axes (X,Y,Z,A,B) are controlled and interfaced to PC via MMC board. Two kinds of CAM S/W such as commercial 5-axis CAM S/W(Euclid) and UG-API are engaged to generate NC code for the developed 5-axis laser cutting machine.

Wine Production Using Osmotic Solution from Dried Mango Process

Annalene S. Garcia,Jae-Ho Park,Hyung-Jin Jeong,Youn-Moon Park,Koo-Min Chung,Jong-Hwa Lee 한국산업식품공학회 2009 산업 식품공학 Vol.13 No.2

This study evaluated the potential of utilizing the osmotic solution from dried mango processing as alternative raw material for mango wine making. Fermentation was carried out using two kinds of yeast strains Saccharomyces bayanus, Lalvin EC-1118 and Saccharomyces cerevisiae, Lalvin D-47 at 20oC for 28 days. Physicochemical analysis during fermentation was performed for each treatment and the resulting wine samples were analyzed for color, volatiles and sensory properties. Results of physicochemical analysis between the two fermenting samples as well as the wine samples show almost similar results regardless of the yeast strains. Wine color of sample wines after storage were not significantly different at p<0.05 and when compared with a commercial mango wine. From the volatile analysis, esters and alcohols constituted majority of the compounds. Production of several esters, alcohols, acids and terpenes were affected by yeast strain used in fermentation. Results of sensory analysis showed that wines fermented by S. bayanus EC-1118 strain was more acceptable although sensory scores between the treatments and the reference wine showed significant differences in all the attributes evaluated, except for bitterness. The utilization of osmotic solution from dried mango process could produce similar properties with existing commercial mango wines although there is still need for further work on the improvement of some sensory attributes of the mango wines.

범용 CNC 밀링에 의한 박막 측벽 파트 가공에 관한 연구

지성희,이동주,신보성,최두선,제태진,이응숙 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

In order to suggest the proper optimal conditions of the CNC milling machining for the Thin-wall surface, some experiments were carried out. The process was applied in the aerospace industry for the machining of light alloys, notably aluminium. In recent year, however, the mold and die industry has begun to use the technology for the production of components, including those manufactured from hardened tool steels. And the end mill is an important tool in the milling process. A typical example for the end mill is the milling of pocket and slot in which a lot of material is removed from the work piece. Therefore the proper selection of cutting parameter for end milling is one of the important factors affecting the cutting cost. In this paper, we choose the optimal parameters(cutting forces) to cut thin-walled Al part by experiment

Growth of InAs Quantum Dot without Introducing Wetting Layer by Alternate Deposition of InAs and GaAs with Quasi-monolayer

종수 김,D. Y. Lee,Gu-Hyun Kim,H. K. Choi,I. H. Bae,J. I. Lee,Jae-Young Leem,Jin Soo Kim,Minhyon Jeon,Nobuyuki Koguchi,S. H. Lee,S. I. Ban,S. K. Kang 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.42 No.III

The structural and optical properties of non-wetting layer InAs quantum dots (QDs) have been investigated by transmission electron microscopy (TEM), photoreflectance (PR) and photoluminescence (PL). By alternate depositing 0.83 $\sim$ 1.2 ML InAs and 1.2 $\sim$ 1.5 ML Ga(Al)As with different period on GaAs surface, the wetting layer of InAs QDs was controlled. TEM images clearly show the formation of QDs by using quasi monolayer (QML) deposition and non-wetting layer of InAs QDs. The QDs formed by using QML could not be grown by Stranski-Krastanov (S-K) growth. In PR measurement, the wetting layer transition is not observed for all the QML QDs. These QML QDs growth mechanisms are explained by adatom migration effect due to surface chemical potential.

CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice

Jung, In-Hyuk,Choi, Jae-Hoon,Jin, Jing,Jeong, Se-Jin,Jeon, Sejin,Lim, Chaeji,Lee, Mi-Ran,Yoo, Ji-Young,Sonn, Seong-Keun,Kim, Young Ho,Choi, Beom Kyu,Kwon, Byoung S.,Seoh, Ju-Young,Lee, Cheol Whan,Kim, The Federation of American Societies for Experimen 2014 The FASEB Journal Vol.28 No.11

<P>CD137 (4-1BB), a member of the tumor necrosis factor receptor superfamily, has been reported to be expressed in atherosclerotic plaques, and to promote lesion formation. However, the role of CD137 in mediating atherosclerotic plaque stability and the possible underlying molecular and cellular mechanisms are poorly understood. Here, apolipoprotein E-deficient (<I>ApoE</I><SUP>−/−</SUP>) and CD137-deficient <I>ApoE</I><SUP>−/−</SUP> (<I>ApoE</I><SUP>−/−</SUP>CD137<SUP>−/−</SUP>) mice fed a chow diet for 66 wk were used. CD137 induces plaque instability, which is characterized by increased plaque necrosis, decreased collagen content, decreased vascular smooth muscle cell (VSMC) content, and increased macrophage infiltration. CD137 also increases the infiltration of effector T (T<SUB>eff</SUB>) cells into plaque lesion sites, resulting in increased interferon-γ (IFN-γ) expression. Interestingly, T<SUB>eff</SUB>-cell-derived IFN-γ inhibits collagen synthesis in atherosclerotic plaques. Furthermore, CD137 activation increases the apoptosis of VSMCs, possibly by decreasing the antiapoptotic regulator, Bcl-2, and subsequently up-regulating cleaved caspase-3. In macrophages, activation of CD137 signaling boosted the oxidized low density lipoprotein-induced expression of matrix metalloproteinase 9 <I>via</I> the p38 mitogen-activated protein kinase and extracellular signal-regulated kinase1/2 signaling pathways. In summary, activation of CD137 signaling decreases the stability of advanced atherosclerotic plaques <I>via</I> its combined effects on T<SUB>eff</SUB> cells, VSMCs, and macrophages.—Jung, I.-H., Choi, J.-H., Jin, J., Jeong, S.-J., Jeon, S., Lim, C., Lee, M.-R., Yoo, J.-Y., Sonn, S.-K., Kim, Y. H., Choi, B. K., Kwon, B. S., Seoh, J.-Y., Lee, C. W., Kim, D.-Y., Oh, G. T. CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice.</P>