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Modelling creep of high strength concrete
D. Dias-da-Costa,E.N.B.S. Júlio 사단법인 한국계산역학회 2010 Computers and Concrete, An International Journal Vol.7 No.6
Recent developments in concrete mixing made possible the production of concretes with high compressive strength showing, simultaneously, high workability. These concretes also present high strengths at young ages, allowing the application of loads sooner. It is of fundamental importance to verify if creep models developed for current concrete still apply to these new concretes. First, a FEM-based software was adopted to test available creep models, most used for normal strength concrete, considering examples with known analytical results. Several limitations were registered, resulting in an incorrect simulation of threedimensional creep. Afterwards, it was implemented a Kelvin-chain algorithm allowing the use of a chosen number of elements, which adequately simulated the adopted examples. From the comparison between numerical and experimental results, it was concluded that the adopted algorithm can be used to model creep of high strength concrete, if the material properties are previously experimentally assessed.
Kim Jun Ho,Reinaldo Abdala-Júnior,Luciana Munhoz,Arthur Rodriguez Gonzalez Cortes,Plauto Christopher Aranha Watanabe,Claudio Costa,Emiko Saito Arita 대한영상치의학회 2020 Imaging Science in Dentistry Vol.50 No.2
Purpose: This study compared 2 cone-beam computed tomography (CBCT) systems in the detection of mechanically simulated peri-implant buccal bone defects in dry human mandibles. Materials and Methods: Twenty-four implants were placed in 7 dry human mandibles. Peri-implant bone defects were created in the buccal plates of 16 implants using spherical burs. All mandibles were scanned using 2 CBCT systems with their commonly used acquisition protocols: i-CAT Gendex CB-500 (Imaging Sciences, Hatfield, PA, USA; field of view [FOV], 8 cm×8 cm; voxel size, 0.125 mm; 120 kVp; 5 mA; 23 s) and Orthopantomograph OP300 (Intrumentarium, Tuusula, Finland; FOV, 6 cm×8 cm; voxel size, 0.085 mm; 90 kVp; 6.3 mA; 13 s). Two oral and maxillofacial radiologists assessed the CBCT images for the presence of a defect and measured the depth of the bone defects. Diagnostic performance was compared in terms of the area under the curve (AUC), accuracy, sensitivity, specificity, and intraclass correlation coefficient. Results: High intraobserver and interobserver agreement was found (P<0.05). The OP300 showed slightly better diagnostic performance and higher detection rates than the CB-500 (AUC, 0.56±0.03), with a mean accuracy of 75.0%, sensitivity of 81.2%, and specificity of 62.5%. Higher contrast was observed with the CB-500, whereas the OP300 formed more artifacts. Conclusion: Within the limitations of this study, the present results suggest that the choice of CBCT systems with their respective commonly used acquisition protocols does not significantly affect diagnostic performance in detecting and measuring buccal peri-implant bone loss.
Catiane S. Souza,Bruno M. Oliveira,Gustavo G. L. Costa,Albert Schriefer,Alessandra Selbach-Schnadelbach,Ana Paula T. Uetanabaro,Carlos P. Pirovani,Gonçalo A. G. Pereira,Alex G. Taranto,Júlio Cézar de 한국미생물학회 2009 The journal of microbiology Vol.47 No.4
Chitin synthase (CHS) is a glucosyltransferase that converts UDP-N-acetylglucosamine into chitin, one of the main components of fungal cell wall. Class III chitin synthases act directly in the formation of the cell wall. They catalyze the conversion of the immediate precursor of chitin and are responsible for the majority of chitin synthesis in fungi. As such, they are highly specific molecular targets for drugs that can inhibit the growth and development of fungal pathogens. In this work, we have identified and characterized a chitin synthase gene of Moniliophthora perniciosa (Mopchs) by primer walking. The complete gene sequence is 3,443 bp, interrupted by 13 small introns, and comprises a cDNA with an ORF with 2,739 bp, whose terminal region was experimentally determined, encoding a protein with 913 aa that harbors all the motifs and domains typically found in class III chitin synthases. This is the first report on the characterization of a chitin synthase gene, its mature transcription product, and its putative protein in basidioma and secondary mycelium stages of M. perniciosa, a basidiomycotan fungus that causes witches’ broom disease of cacao.
Kuguacin: biological activities of triterpenoid from Momordica charantia—a scoping review
Pedro Henrique Sette-de-Souza,Brenda Alencar Araújo Souza,Moan Jéfter Fernandes Costa,Fábio Andrey da Costa Araújo 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.1
The Momordica charantia is a vegetable crop used worldwide due to its biological activities. Investigations into the pharmacological activities of the M. charantia revealed that it presented a wide range of properties, including antimicrobial, anti-cancer, anti-diabetic, and anti-obesity. Over the years, the M. charantia compounds have been identified and studied. In this study, we highlighted the Kuguacin, a triterpenoid isolated from any M. charantia parts. Thus, we aimed to synthesize the scientific knowledge about the Kuguacin biological activities and identify gaps in this area. We performed a scoping review using the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) to design the study’s protocol, with search in PUBMED, EMBASE, SCOPUS, Science Direct, and SciFinder databases. Most of the studies used in vitro methods, and the Kuguacin were isolated from leaves, vines, fruits, and roots. Studies reported the anti-diabetic, anti-cancer, anti-influenza, anti-HIV, and anti-tuberculosis activities of the Kuguacin.
Kelly Mônica Marinho e Lima,José Francisco Silva Costa Júnior,Wagner Coelho de Albuquerque Pereira,Liliam Fernandes de Oliveira 대한초음파의학회 2018 ULTRASONOGRAPHY Vol.37 No.1
This review aimed to describe the state of the art in muscle-tendon unit (MTU) assessment by supersonic shear wave imaging (SSI) elastography in states of muscle contraction and stretching, during aging, and in response to injury and therapeutic interventions. A consensus exists that MTU elasticity increases during passive stretching or contraction, and decreases after static stretching, electrostimulation, massage, and dry needling. There is currently no agreement regarding changes in the MTU due to aging and injury. Currently, the application of SSI for the purpose of diagnosis, rehabilitation, and physical training remains limited by a number of issues, including the lack of normative value ranges, the lack of consensus regarding the appropriate terminology, and an inadequate understanding of the main technical limitations of this novel technology
Bárbara Couto Ramos,Bruna Raquel da Silva Izar,Jéssica Lourdes Costa Pereira,Priscilla Sena Souza,Claudia Scigliano Valerio,Fabrício Mesquita Tuji,Flávio Ricardo Manzi 대한영상치의학회 2016 Imaging Science in Dentistry Vol.46 No.1
Panoramic radiographs are a relatively simple technique that is commonly used in all dental specialties. In panoramic radiographs, in addition to the formation of real images of metal objects, ghost images may also form, and these ghost images can hinder an accurate diagnosis and interfere with the accuracy of radiology reports. Dentists must understand the formation of these images in order to avoid making incorrect radiographic diagnoses. Therefore, the present study sought to present a study of the formation of panoramic radiograph ghost images caused by metal objects in the head and neck region of a dry skull, as well as to report a clinical case in order to warn dentists about ghost images and to raise awareness thereof. An understanding of the principles of the formation of ghost images in panoramic radiographs helps prevent incorrect diagnoses.
Flávia Thamiris Figueiredo Pacheco,Silvia Souza de Carvalho,Samara Alves Santos,Gisele Maria Trindade das Chagas,Mariana Conceição Santos,Jéssica Gleide Souza Santos,Hugo da Costa-Ribeiro Júnior,Terez 대한진단검사의학회 2020 Annals of Laboratory Medicine Vol.40 No.5
Background: Giardia duodenalis is conventionally diagnosed in fecal samples using parasitological methods. However, sensitivity is poor when only a single sample is analyzed, due to intermittent excretion of cysts in feces. Alternatively, the serum antibodies to G. duodenalis can be used for parasite diagnosis and epidemiological studies to determine previous exposure. We compared the rate of G. duodenalis infection between serum anti-Giardia IgG and IgA antibodies and fecal examination in Brazilian children. Methods: Fecal and serum samples were tested from 287 children at a clinical laboratory and from 187 children at daycare centers. Fecal samples were processed using conventional parasitological methods and coproantigen detection for Giardia diagnosis. Serum samples were tested using an in-house ELISA for detection of anti-Giardia IgG and IgA. Results: G. duodenalis was found in 8.2% (N=39) of the 474 children analyzed. The sensitivity and specificity of ELISA were 80.0% and 90.0% for IgG and 80.0% and 83.3% for IgA, respectively. The total positivity rate of anti-Giardia IgG and IgA in the sera was 13.9% (N=66) and 23.6% (N=112). The agreement between the positivity of specific antibodies and the detection of G. duodenalis in feces was moderate for ELISA-IgG, kappa index (95% CI)=0.543 (0.422–0.664), and mild for ELISA-IgA, kappa index (95% CI)=0.283 (0.162–0.404). Among the children infected with other enteroparasites, 11.6% (N=10) and 24.4% (N=21) showed reactivity to anti-Giardia IgG and to IgA, respectively. This cross-reactivity was more frequent in samples from children infected with Endolimax nana and Entamoeba coli. Conclusions: The higher frequency of specific antibody reactivity compared with G. duodenalis diagnosis in feces could reflect continuous exposure of children to G. duodenalis infection, resulting in long-lasting immunological memory and/or cross-reactivity with other intestinal amoebas.
The pulsation modes of the pre-white dwarf PG 1159-035
Costa, J. E. S.,Kepler, S. O.,Winget, D. E.,O'Brien, M. S.,Kawaler, S. D.,Costa, A. F. M.,Giovannini, O.,Kanaan, A.,Mukadam, A. S.,Mullally, F.,Nitta, A.,Provenç,al, J. L.,Shipman, H.,Wood, M. A EDP Sciences 2008 Astronomy and astrophysics Vol.477 No.2