S-496 Prevalence of chronic disease and its controlled status according to income level

( Donghoon Lee ),( Hoseok Koo ),( Seung Hyuk Kim ),( Woneui Yoon ),( Yoollae Kim ),( Jiyeon Kang ),( Junho Kim ),( Hang-il Goh ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

The chronic disease and income level now became main theme in poor national economic situation. We examined the prevalence, well-controlled of chronic disease according to income level. The data from the KNHANES from 2008 to 2014, which is a stratified, multistage, probability-cluster sampling method in a survey of South Korean. SBP was inversely correlated with income level (p<0.001). DBP showed no relation. The prevalence of hypertension and DMwasthe highest in the low income group.In the low income group, the ratio of well controlledchronic disease, SBP in patients with hypertension showed a lower trend. And in the high income group, the ratio of well controlledstatus in patients with DM and CKD also showed high than other groups.After adjusting for age, BMI, SBP, DBP, HbA1c, serum creatinine, income level significantly affect the prevalence of chronic disease (for income, β=0.184, CI 1.105~1.042). The prevalence of not using essential medical service for chronic disease was the highest in low, low-mid income group because of economic reasons.In low, low-mid income group, the prevalence of chronic diseasewas higher and the ratio of well controlled chronic disease than other groups.

Dietary Reference Intakes of sodium for Koreans: focusing on a new DRI component for chronic disease risk reduction

김현자,이연경,Koo Hoseok,신민정 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.no.sup1

Sodium is a physiologically essential nutrient, but excessive intake is linked to the increased risk of various chronic diseases, particularly cardiovascular. It is, therefore, necessary to accomplish an evidence-based approach and establish the Korean Dietary Reference Intakes (KDRIs) index, to identify both the nutritional adequacy and health effects of sodium. This review presents the rationale for and the process of revising the KDRIs for sodium and, more importantly, establishing the sodium Chronic Disease Risk Reduction Intake (CDRR) level, which is a new specific set of values for chronic disease risk reduction. To establish the 2020 KDRIs for dietary sodium, the committee conducted a systematic literature review of the intake–response relationships between the selected indicators for sodium levels and human chronic diseases. In this review, 43 studies published from January 2014 to December 2018, using databases of PubMed and Web of Science, were finally included for evaluating the risk of bias and strength of evidence (SoE). We determined that SoE of the relationship between dietary sodium and cardiovascular diseases, cerebrovascular disease, and hypertension, was moderate to strong. However, due to insufficient scientific evidence, we were unable to establish the estimated average requirement and the recommended nutrient intake for dietary sodium. Therefore, the adequate intake of sodium for adults was established to be 1,500 mg/day, whereas the CDRR for dietary sodium was established at 2,300 mg/day for adults. Intake goal for dietary sodium established in the 2015 KDRIs instead of the tolerable upper intake level was not presented in the 2020 KDRIs. For the next revision of the KDRIs, there is a requirement to pursue further studies on nutritional adequacy and toxicity of dietary sodium, and their associations with chronic disease endpoint in the Korean population.

Dietary Reference Intakes of sodium for Koreans: focusing on a new DRI component for chronic disease risk reduction

김현자,이연경,Koo Hoseok,신민정 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.3

Sodium is a physiologically essential nutrient, but excessive intake is linked to the increased risk of various chronic diseases, particularly cardiovascular. It is, therefore, necessary to accomplish an evidence-based approach and establish the Korean Dietary Reference Intakes (KDRIs) index, to identify both the nutritional adequacy and health effects of sodium. This review presents the rationale for and the process of revising the KDRIs for sodium and, more importantly, establishing the sodium Chronic Disease Risk Reduction Intake (CDRR) level, which is a new specific set of values for chronic disease risk reduction. To establish the 2020 KDRIs for dietary sodium, the committee conducted a systematic literature review of the intake–response relationships between the selected indicators for sodium levels and human chronic diseases. In this review, 43 studies published from January 2014 to December 2018, using databases of PubMed and Web of Science, were finally included for evaluating the risk of bias and strength of evidence (SoE). We determined that SoE of the relationship between dietary sodium and cardiovascular diseases, cerebrovascular disease, and hypertension, was moderate to strong. However, due to insufficient scientific evidence, we were unable to establish the estimated average requirement and the recommended nutrient intake for dietary sodium. Therefore, the adequate intake of sodium for adults was established to be 1,500 mg/day, whereas the CDRR for dietary sodium was established at 2,300 mg/day for adults. Intake goal for dietary sodium established in the 2015 KDRIs instead of the tolerable upper intake level was not presented in the 2020 KDRIs. For the next revision of the KDRIs, there is a requirement to pursue further studies on nutritional adequacy and toxicity of dietary sodium, and their associations with chronic disease endpoint in the Korean population.

Dietary Reference Intakes of sodium for Koreans: focusing on a new DRI component for chronic disease risk reduction

Hyun Ja Kim,Yeon-Kyung Lee,Hoseok Koo,Min-Jeong Shin 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.no.sup1

Sodium is a physiologically essential nutrient, but excessive intake is linked to the increased risk of various chronic diseases, particularly cardiovascular. It is, therefore, necessary to accomplish an evidence-based approach and establish the Korean Dietary Reference Intakes (KDRIs) index, to identify both the nutritional adequacy and health effects of sodium. This review presents the rationale for and the process of revising the KDRIs for sodium and, more importantly, establishing the sodium Chronic Disease Risk Reduction Intake (CDRR) level, which is a new specific set of values for chronic disease risk reduction. To establish the 2020 KDRIs for dietary sodium, the committee conducted a systematic literature review of the intake-response relationships between the selected indicators for sodium levels and human chronic diseases. In this review, 43 studies published from January 2014 to December 2018, using databases of PubMed and Web of Science, were finally included for evaluating the risk of bias and strength of evidence (SoE). We determined that SoE of the relationship between dietary sodium and cardiovascular diseases, cerebrovascular disease, and hypertension, was moderate to strong. However, due to insufficient scientific evidence, we were unable to establish the estimated average requirement and the recommended nutrient intake for dietary sodium. Therefore, the adequate intake of sodium for adults was established to be 1,500 mg/day, whereas the CDRR for dietary sodium was established at 2,300 mg/day for adults. Intake goal for dietary sodium established in the 2015 KDRIs instead of the tolerable upper intake level was not presented in the 2020 KDRIs. For the next revision of the KDRIs, there is a requirement to pursue further studies on nutritional adequacy and toxicity of dietary sodium, and their associations with chronic disease endpoint in the Korean population.

Usefulness of NGAL to confirm long-term renal prognosis after non-cardiac surgery

( Se Jun Park ),( Seo Hun Kim ),( Seo Young Yun ),( Seung Hyup Kim ),( Hoseok Koo ),( Haeng Il Ko ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

Purpose: The neutrophil gelatinase-associated lipocalin (NGAL) level following cardiac surgery is useful for predicting acute kidney damage. However, there is insufficient conclusive evidence as to whether NGAL can be used to predict subclinical acute kidney injury following non-cardiac surgery. Methods: We measured serum NGAL and creatinine levels in 41 patients following non-cardiac surgery, and used the definition of sublinical AKI with NGAL Results: The study included a total of 41 patients. The mean age was 64.65 ± 17.09 years. The value of serum creatinine was decreased 4 hours after surgery and increased 12 hours after surgery. The serum NGAL decreased after 4 hours after surgery and continuedto decrease after 12 hours after surgery. The incidence of subclinical acute kidney injury determined by the 4 hour serum NGAL level was 16 (39.0%), and the incidence of serum creatinine elevation over CV was 8 (19.5%). The incidence of subclinical acute kidney injury determined by the 12 hour serum NGAL level was 11(26.8%), and the incidence of serum creatinine over CV was 15 (36.5%). The elevation of NGAL over CV was more rapid than the serum creatinine 4 hours after surgery. For a patient with subclinical acute kidney injury, we tested the serum creatinine 6 and 12 months after surgery. The incidence of serum creatinine elevation was higher in patients with subclinical acute kidney injury compared to patients without injury, suggesting a clinical implication. Conclusions: We verified the usefulness of the serum NGAL level as a predictive factor for long-term renal prognosis in patient with subclinical AKI after non-cardiac surgery. Keywords: NGAL; Acute kidney injury; Predictive factor; Non-cardiac surgery; Creatinine

차량 파라미터 변경에 따른 ESC ECU의 강인성 분석과 이를 통한 ESC파 라미터 선정기준 체계 구축 - Part Ⅰ

이강원(Kangwon Lee),김원욱(Wonwook Kim),이종일(Jonil Lee),김영우(Youngwoo Kim),구형찬(Hyoungchan Koo),김호석(Hoseok Kim),김선희,박기홍(Kihong Park) 한국자동차공학회 2010 한국자동차공학회 학술대회 및 전시회 Vol.2010 No.11

In order to advance vehicle stability control strategies and provide enhanced customer benefits, a methodology for direct yaw control with a Vehicle Stability Controller (ESC, Electronic Stability Control) has been developed. Therefore, there are many studies of the improvement of ESC system performance and control system logics but there are very few studies about the relationship vehicle parameters effect on vehicle dynamic characteristics with ESC system. Especially, during the new vehicle development process, vehicle parts changing contents are occurred very open and it required to be taken too much man-hour for follow up the changing contents and the work scope gets necessarily expanded. So there are required to study about vehicle dynamic performance effect with vehicle parameters changing and ESC performance tolerable limits by vehicle parameter changes. In this paper, the vehicle parameters effect on vehicle dynamic characteristics have been studied and confirmed using computer simulation with ABS/TCS/ESC System and software vehicle model constructed by CarSim and Matlab/Simulink. Finally, through this Study, we will present the ESC performance guideline by vehicle parameter change for using of vehicle ESC performance development and validation.