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Lymphadenectomy issues in endometrial cancer
Yosuke Konno,Hiroshi Asano,Ayumi Shikama,Daisuke Aoki,Michihiro Tanikawa,Akinori Oki,Koji Horie,Akira Mitsuhashi,Akira Kikuchi,Hideki Tokunaga,Yasuhisa Terao,Toyomi Satoh,Kimio Ushijima,Mitsuya Ishika 대한부인종양학회 2021 Journal of Gynecologic Oncology Vol.32 No.2
Objectives: This review aims to introduce preoperative scoring systems to predict lymphnode metastasis (LNM) and ongoing clinical trials to investigate the therapeutic role oflymphadenectomy for endometrial cancer. Methods: We summarized previous reports on the preoperative prediction models forLNM and evaluated their validity to omit lymphadenectomy in our recent cohorts. Next, wecompared characteristics of two ongoing lymphadenectomy trials (JCOG1412, ECLAT) toexamine the survival benefit of lymphadenectomy in endometrial cancer, and described thedetails of JCOG1412. Results: Lymphadenectomy has been omitted for 64 endometrial cancer patients who met low risk criteria to omit lymphadenectomy using our scoring system (LNM score) and no lymphaticfailure has been observed. Other two models also produced comparable results. Two randomizedphase III trials to evaluate survival benefit of lymphadenectomy are ongoing for endometrialcancer. JCOG1412 compares pelvic lymphadenectomy alone with pelvic and para-aorticlymphadenectomy to evaluate the therapeutic role of para-aortic lymphadenectomy for patients atrisk of LNM. For quality assurance of lymphadenectomy, we defined several regulations, includinglower limit of the number of resected nodes, and submission of photos of dissected area toevaluate thoroughness of lymphadenectomy in the protocol. The latest monitoring report showedthat the quality of lymphadenectomy has been well-controlled in JCOG1412. Conclusion: Our strategy seems reasonable to omit lymphadenectomy and could begeneralized in clinical practice. JCOG1412 is a high-quality lymphadenectomy trial in terms ofthe quality of surgical procedures, which would draw the bona-fide conclusions regarding thetherapeutic role of lymphadenectomy for endometrial cancer.
Tracking of 3D Sound Source Location by Particle Filter with TDOA and Signal Power Ratio
Norikazu Ikoma,Osamu Tokunaga,Hideaki Kawano,Hiroshi Maeda 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
A new sound source tracking method in 3 dimensional space using state space modeling approach and particle filter as a state estimation method has been proposed. Not only TDOA (Time Difference Of Arrival) as our previous works including by the authors, but also using power ratio of two sound signals from microphone pair are effectively used in formulation of state space model. Simulational experiments consisting of 1) fundamental tracking with four microphones and 2) human head tracking in car cabin have been conducted with efficient performance in SNR 20dB environment with about 3,000 number of particles.
Development of a Plasma Control System for Steady-state Operation on QUEST
Makoto Hasegwa,Kazuo Nakamura,Hideki Zushi,Kazuaki Hanada,Akihide Fujisawa,Keisuke Matsuoka,Hiroshi Idei,Yoshihiko Nagashima,Kazutoshi Tokunaga,Shoji Kawasaki,Hisatoshi Nakashima,Aki Higashijima 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.8
A drift error correction technique with machine vision and a real-time equilibrium calculation codehave been developed on the QUEST (Q-shu university experiment with the steady-state sphericaltokamak) for steady-state operation. The drift error caused by the long time-integration of magneticraw signals has to be removed. With a captured image of the plasma’s cross section, the plasma’sposition is identified by use of image filters. The measured magnetic flux values are corrected to thecalculated flux values estimated by using this plasma position. The correction with the capturedimage work as expected in the preliminary result using a flashlight instead of a plasma.
HIGH ANGULAR RESOLUTION [Fe II] λ1.644 μ SPECTROSCOPY OF YSOS WITH SUBARU TELESCOPE
PYO TAE-SOO,HAYASHI MASAHIKO,NAOTO KOBAYASHI,TERADA HIROSHI,TOKUNAGA ALAN T. The Korean Astronomical Society 2005 Journal of The Korean Astronomical Society Vol.38 No.2
We present results of the velocity-resolved spectroscopy of the [Fe II] $\lambda$1.644${\mu}m$ emission toward outflow sources with the Subaru Telescope at the angular resolution of 0.apos;16 ${\~}$ 0.apos;5 arcseconds. The observed sources are L1551 IRS 5, DG Tau, HL Tau and RW Aur, which are located in the Taurus-Aurigae Molecular Cloud, one of the closest star forming regions (0.apos;1 = 14 AU). We were able to resolve outflow structure in the vicinity of the sources at a scale of a few tens of AU. The position-velocity diagram of each object shows two velocity components: the high velocity component (HVC: 200 - 400 km $s^{-l}$) and the low velocity component (LVC: 50 - 150 km $s^{-l}$), which are clearly distinct in space and velocity. The HVC may be a highly collimated jet presumed from its narrow velocity width and high velocity. The LVC, on the other hand, may be a widely opened disk wind inferred from its broad velocity width and low velocity. The spectrum taken perpendicular to the L1551 IRS 5 outflow at its base shows that the LVC has a spatially wide subcomponent, supporting the above interpretation. We demonstrated that the [Fe II] 1.644 $\mu$ spectroscopy is a very powerful tool for the studies of fast jets and winds that directly emanate from star-disk systems.