Research Articles : Geographic Genetic Contour of A Leaf Beetle, Chrysolina aurichalcea (Coleoptera: Chysomelidae), on the Basis of Mitochondrial COI Gene and Nuclear ITS2 Sequences

( Joong Won Park ),( Sun Young Park ),( Ah Rha Wang ),( Min Jee Kim ),( Hae Chul Park1 ),( Iksoo Kim ) 한국잠사학회 2011 International Journal of Industrial Entomology Vol.23 No.1

The leaf beetle, Chrysolina aurichalcea (Coleoptera: Chysomelidae), is a pest damaging plants of Compositae. In order to understand the genetic diversity and geographic variation we sequenced a portion of mitochondrial COI gene (658 bp) and complete nuclear internal transcribed spacer 2 (ITS2) of the species collected from seven Korean localities. A total of 17 haplotypes (CACOI01~CACOI17), with the maximum sequence divergence of 3.04% (20 bp) were obtained from COI gene sequence, whereas 16 sequence types (ITS2CA01~ITS2CA16), with the maximum sequence divergence of 2.013% (9 bp) were obtained from ITS2, indicating substantially larger sequence divergence in COI gene sequence. Phylogenetically, the COI gene provided two haplotype groups with a high nodal support (≥87%), whereas ITS2 provided only one sequence type group with a high nodal support (≥92%). The result of COI gene sequence may suggest the presence of historical biogeographic barriers that bolstered genetic subdivision in the species. Different grouping pattern between COI gene and ITS2 sequences were interpreted in terms of recent dispersal, reflected in the ITS2 sequence. Finding of unique haplotypes and sequence types only from Beakryeng-Islet population was interpreted as an intact remnant of ancient polymorphism. As more samples are analyzed using further hyper-variable marker, further fruitful inference on the geographic contour of the species might be available.

공급사슬에서 수량할인과 수익공유를 반영한 계약

박세호(Se Ho Park),이영해(Young Hae Lee),조동원(Dong Won Cho) 한국SCM학회 2012 한국SCM학회지 Vol.12 No.2

One of the most important reasons in pursuit of supply chain management is to prevent sub-optimization caused by decentralized decision making over the various entities. As supply chain coordination approach to overcome such a setting, contract mechanisms have frequently been used. However, a coordinated supply chain might fail to provide additional profit to one of the players. In result, it is necessary that a contract mechanism is designed to achieve the same profit in a centralized situation (coordination) and to improve the benefit of all the supply chain players (winwin). In this paper, we address supply chain contract based on revenue sharing and quantity discount considering price and service level. We show that the trade parameters among different entities in the supply chain contract can be chosen to achieve coordination and a win-win outcome.

소아 알레르기비염의 경제적 부담 평가를 위한 다기관 조사

공도연 ( Do Youn Kong ),김경원 ( Kyung Won Kim ),김우경 ( Woo Kyung Kim ),민택기 ( Taek Ki Min ),박용민 ( Yong Mean Park ),안재억 ( Jae Ouk Ahn ),양현종 ( Hyeon Jong Yang ),염혜영 ( Hye Yung Yum ),윤혜선 ( Hae Sun Yoon ),전유훈 ( 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2012 소아알레르기 및 호흡기학회지 Vol.22 No.2

목적: 알레르기비염의 유병률은 전 세계적으로 급격히 증가하고 있으며, 그에 따른 경제적 부담도 증가하고 있다. 그러나, 소아 알레르기 질환이 미치는 경제적 부담에 관한 국내 연구는 제한적이어서 소아 알레르기비염이 환자와 그 가족에게 미치는 경제적 부담을 산출하고자 본 연구를 진행하였다. 방법: 2008년 7월 1일부터 9월 31일까지 서울시 6개 2-3차 의료기관을 방문한 18세 이하 소아 알레르기비염 환자 및 보호자를 대상으로 설문 조사를 진행하였다. 설문을 통해 직접 의료비 (병·의원 진료비, 및 약제비 한방 진료비 및 약제비, 보완/대체요법비), 직접비의료비 (교통비, 환경개선비), 그리고 간접비용 (월 평균 노동 손실)을 조사하였고 그 결과를 질환의 중증도 및 유병 기간에 따라 분석하여 그 차이를 비교하였다. 결과: 모집된 262명의 대상 중 174명(66.4%)이 남자였고, 평균 연령은 6.54세였다. 대상군의 연간 평균 직접 의료비는 177만 원이었고 직접비 의료비는 57만 원이었다. 비록 통계학적 유의성은 없었지만, 알레르기비염의 중증도가 증가할수록 직접 의료비가 증가하는 경향을 보였고, (P=0.053) 유병 기간 또한 직접 의료비의 증가와 유의한 양의 상관 관계를 보였다. (R=0.195, P=0.002) 대상 환자 보호자의 약 17%가 아이의 알레르기비염으로 인해 직장에 결근 또는 조퇴를 경험한 것으로 조사되어 사회적 간접비용을 미루어 생각할 수 있었다. 결론: 알레르기비염이 미치는 경제적 부담은 질환의 중증도가 심할수록, 그리고 유병 기간이 길수록 증가하며, 이는 특히 한방 진료 및 치료비와 보완/대체요법비의 증가에 기인한 것으로 조사되었다. 따라서 알레르기비염으로 인한 경제적 부담을 줄이기 위해서는 환자와 보호자를 대상으로 근거 중심의 치료를 할 수 있도록 지속적이고 체계적인 교육이 필요할 것으로 사료된다. Purpose: The prevalence of allergic rhinitis is rapidly increasing and results in relatively high socio-economic burden on their family and community. However, studies on the economic burden of pediatric allergic rhinitis in Korea are limited. Therefore, we conducted this study to investigate the impact of pediatric allergic rhinitis on economic burden. Methods: Two hundred sixty two children with allergic rhinitis were enrolled in 6 secondary or tertiary medical centers in Seoul from July to September, 2008. We collected data of the economic burden of allergic rhinitis (direct medical costs, direct nonmedical costs, and indirect costs) by face to face questionnaire survey. We compared the economic burden according to the severity and the duration of allergic rhinitis. Results: The mean age of subjects was 6.54 years, and male were 174 (66.4%). Direct medical costs (10,000 Korean Won/yr) were 177.75, and direct nonmedical costs were 57.92. Although, there was no statistical significance, direct medical costs showed increasing trends in severe allergic rhinitis. (P=0.053) In addition, direct medical costs were positively correlated with duration of allergic rhinitis.( R=0.195, P=0.002). About 17% of the parents who care the allergic rhinitis children experienced the work absence due to their child s illness. Conclusion: The economic burdens of allergic rhinitis were positively correlated with the severity and duration of illness. Particularly costs for alternative medicine including oriental medicine` were related with severity and duration allergic rhinitis. Therefore, special efforts for education with evidence based treatment strategy are necessary to decrease the economic burden of allergic rhinitis.

알레르기 환자에서 한방 이외의 대체 요법의 사용 현황에 대한 다기관 조사

이현정 ( Hyun Jung Lee ),이재현 ( Jae Hyun Lee ),이용원 ( Yong Won Lee ),김철우 ( Cheol Woo Kim ),동헌종 ( Hun Jong Dhong ),박해심 ( Hae Sim Park ),조영주 ( Young Joo Cho ),조진희 ( Jin Hee Cho ),조상헌 ( Sang Heon Cho ),편복양 ( 대한내과학회 2011 대한내과학회지 Vol.80 No.1

Background/Aims: The use of unproven complementary/alternative medicine (CAM) to treat allergies is popular in Korea. We conducted a multicenter survey of the current use of CAM other than herbal medication in Korean allergy patients. Methods: This study enrolled 510 adults with allergic diseases, including asthma, allergic rhinitis, atopic dermatitis, and chronic urticaria, from ten hospitals. They underwent a structured questionnaire interview and clinical assessment of the prevalence, motivation, costs, and subjective assessment of CAM. Results: Of the patients, 16.7% used at least one type of CAM to treat their allergic diseases. Common types of CAM were diet (48.6%), aroma therapy (23.8%), massage (14.3%), breathing exercises (7.6%), baths (5.7%), and mind control (5.7%). The therapeutic effects of CAM included improved in patients using mind control (50%), diet (50%), breathing exercises (75%), and baths (33.3%), but worse in patients using aroma therapy (28%), and massage (26.7%). About 36.4% of the patients used CAM more than four times per year, and the average cost per CAM user was 370,000 won/year. The main reason for trying CAM was `hope to improve my constitution`. Conclusions: CAM is used widely for treating allergic diseases in Korea. Detailed knowledge of CAM and patient education are important. Further studies of the clinical efficacy of CAM are needed. (Korean J Med 2011;80:68-77)

A CMOS VLSI Integrated RF Transceiver System for Wireless Sensor Networks in Sub-㎓

Hae-Moon Seo,Yeon Kug Moon,Yong-Kuk Park,DongSu Kim,Kwang-Ho Ahn,Sung-Ok Lim,Kwang-Ho Won,Sung-Dong Kim 한국통신학회 2006 한국통신학회 학술대회논문집 Vol.2006 No.7

Thermal degradation mechanism of ferritic alloy (Crofer 22 APU)

Park, Mansoo,Shin, Ji-Su,Lee, Sanghyeok,Kim, Hyo-Jin,An, Hyegsoon,Ji, Ho-il,Kim, Hyoungchul,Son, Ji-Won,Lee, Jong-Ho,Kim, Byung-Kook,Lee, Hae-Weon,Yoon, Kyung Joong Elsevier 2018 Corrosion science Vol.134 No.-

<P><B>Abstract</B></P> <P>The oxidation mechanism of Crofer 22 APU, one of the most preferred interconnects for solid oxide fuel cells (SOFCs), was explored in air. Crofer 22 APU showed two-step thermal behavior during thermal exposure, based on the varying growth rate of the chromia scale. The growth rate of the chromia scale abruptly increased at a certain annealed time, suggesting that its formation kinetics changed during thermal exposure. A thickness prediction model for the entire scale of Crofer 22 APU, based on the observed two-step oxidation mechanism, was established using the parabolic rate law.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The oxidation mechanism of Crofer 22 APU was investigated at high temperatures. </LI> <LI> The growth rate of chromia increased abruptly due to oxygen that penetrates the Cr-Mn oxide. </LI> <LI> Two-step thermal behavior for the growth of the scale was proposed. </LI> <LI> A thickness prediction model for the scale of Crofer 22 APU was established. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

혼합 모델 및 다중 가설 검정을 이용한 신호와 잡음의 분리

Hae-sang Park,Si-Won Yoo,Chi-Hyuck Jun 대한산업공학회 2009 대한산업공학회 춘계학술대회논문집 Vol.2009 No.5

It is necessary to separate the signal and noise in quantitative analysis of inclusion using optical emission spectroscopy data. It is assumed that the noise follows a Gaussian distribution and the signal follows a Gamma distribution, thus the underlying distribution of data will be a mixture of Gaussian and Gamma distribution. The parameters of the mixture model can be estimated from the EM algorithm. Then the signals and noises will be classified by using a fixed threshold approach based on multiple testing using positive false discovery rate and Bayes error. The proposed method is applied to a real data and a simulation is carried out to compare the performance with the previous method like 3 sigma rule.

Relationship Between Aggravation of Seizures and Methylphenidate Treatment in Subjects with Attention-Deficit/Hyperactivity Disorder and Epilepsy

Park, Jangho,Choi, Hae-Won,Yum, Mi-Sun,Ko, Tae-Sung,Shon, Seung-Hyun,Kim, Hyo-Won Mary Ann Liebert 2018 Journal of child and adolescent psychopharmacology Vol.28 No.8

Disease-specific impairment of the quality of life in adult patients with chronic spontaneous urticaria

Won-Sun Choi,Eun-Soo Lim,반가영,Ji-Hye Kim,Yoo Seob Shin,Hae Sim Park,Young Min Ye 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.1

Background/Aims: Chronic urticaria (CU) is a common skin disorder characterized by wheals and pruritus lasting more than 6 weeks. Due to its long duration and changeable symptoms, the quality of life (QOL) of patients with CU can be impaired substantially. We evaluated the CU-QOL, a previously validated CU-specific QOL measure, and investigated factors influencing QOL in chronic spontaneous urticaria (CSU) patients. Methods: A hospital-based cross-sectional study was performed on 390 adult patients diagnosed with CSU from March 2009 to December 2012 at the Allergy and Clinical Immunology Clinic at Ajou University Hospital. The CU-QOL questionnaire, urticaria activity score (UAS), combined angioedema, and serum total immunoglobulin E (IgE) levels were investigated. Results: The average CU-QOL score obtained from the questionnaire was 70.6 (of 100 points). The CU-QOL scores correlated significantly with the UAS, particularly with the 15-point UAS (UAS-15; coefficient –0.532, p < 0.01) rather than the 6-point UAS (–0.502, p < 0.01). The patients presenting with angioedema and urticaria had poorer scores in the urticaria symptom domain than those with urticaria alone (37.4 vs. 46.9, p = 0.004). Log-transformed serum total IgE levels correlated significantly with CU-QOL (–0.131, p < 0.05). Multivariate regression models indicated that severe CU (UAS-15 score ≥ 13), log (total IgE), and the presence of angioedema were significant predictors of impaired CU-QOL (< 85 points). Conclusions: CU has a substantial negative impact on QOL. The assessment of UAS-15, total IgE, and the presence of angioedema can be useful to predict QOL of the patients with CSU.

Influence of vanadium doping on the electrochemical performance of nickel oxide in supercapacitors

Park, Hae Woong,Na, Byung-Ki,Cho, Byung Won,Park, Sun-Min,Roh, Kwang Chul The Royal Society of Chemistry 2013 Physical chemistry chemical physics Vol.15 No.40

<P>In this study, V-doped NiO materials were prepared by simple coprecipitation and thermal decomposition, and the effect of the vanadium content on the morphology, structural properties, electrochemical behavior, and cycling stability of NiO upon oxidation and reduction was analyzed for supercapacitor applications. The results show an improvement in the capacitive characteristics of the V-doped NiO, including increases in the specific capacitance after the addition of just 1.0, 2.0, and 4.0 at% V. All V<SUB><I>x</I></SUB>Ni<SUB>1−<I>x</I></SUB>O electrodes (<I>x</I> = 0.01, 0.02, 0.04) exhibited higher specific capacitances of 371.2, 365.7, and 386.2 F g<SUP>−1</SUP> than that of pure NiO (303.2 F g<SUP>−1</SUP>) at a current density of 2 A g<SUP>−1</SUP> after 500 cycles, respectively. The V<SUB>0.01</SUB>Ni<SUB>0.99</SUB>O electrode showed good capacitance retention of 73.5% at a current density of 2 A g<SUP>−1</SUP> for more than 500 cycles in a cycling test. Importantly, the rate capability of the V<SUB>0.01</SUB>Ni<SUB>0.99</SUB>O electrode was maintained at about 84.7% as discharge current density was increased from 0.5 A g<SUP>−1</SUP> to 4 A g<SUP>−1</SUP>.</P> <P>Graphic Abstract</P><P>The V-doped NiO electrode materials were synthesized by simple co-precipitation and thermal decomposition. By modifying and optimizing the electrode materials, a 1.0 at% V-doped NiO electrode showed enhanced electrochemical performance due to its unique cross-linked porous nanostructure. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3cp52498a'> </P>