http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
스테로이드가 신생 흰쥐 해마형성체 신경원의 퇴행에 미치는 영향
임경택,채희선,김성수,김경용,이원복 중앙대학교 의과대학 의과학연구소 1998 中央醫大誌 Vol.23 No.1
The influences of adrenal corticosteroid on the development and regression of the neurons of hippocampal and dentate were examined in the steroid overloaded neonatal rats. The results obtained were as follows. The regression occurred naturally in numerous dentate granule cells and hippocampal pyramidal cells, which was the apoptotic process. The apoptotic granule cells in dentate gyrus decreased in number with steroid overload, and this change was more prominent at 6 days than at 4 days. The decrease in the number of apoptotic neurons by steroid overload occurred only in the upper limb of dentate gyrus at 6 days. The gradient of regression in dentate gyrus had no relation with the gradient of neurogenesis, and the regression of hippocampal pyramidal cells decreased in the gyrus but not in CA regions. In conclusion, the cell death occurred in neurons of hippocampal formation, which was the process of apoptosis. The adrenal corticosteroid seemed to be influential significantly on the development and regression of the neurons.
소의 분변과 도체에서 shiga toxin-producing Escherichia coli의 분리와 특성
채희선 ( Hee Sun Chae ),김능희 ( Neung Hee Kim ),한혜진 ( Hye Jin Han ),손홍락 ( Hong Rak Son ),김창기 ( Chang Ki Kim ),김선흥 ( Sun Heung Kim ),이정학 ( Jung Hark Lee ),김종택 ( Jong Taek Kim ) 한국가축위생학회 2009 韓國家畜衛生學會誌 Vol.32 No.3
Shiga toxin (Stx)-producing Escherichia coli (STEC) strains can cause broad spectrum of human disease, including diarrhea, hemorrhagic colitis, and the life-threatening hemolytic uremic colitis (HUS). We examined 868 samples was taken from bovine feces and carcass from January to December 2008 in Seoul. Twenty two (9.5%) shiga toxin -producing Escherichia coli were isolated from the 230 of bovine feces, and two (0.31%) were isolated from the 638 of carcasses. Serotype of E. coli isolates were O157 (10, 41.6%), O26 (10, 41.6%), O111 (1, 4.2%) and UT (3, 12.6%). In PCR, the isolates displayed three different stx gene combination (stx1〔2, 8.4%〕], stx2〔3, 12.6%〕and stx1 and stx2〔19, 87.5%〕). The eaeA and hlyA gene were found in 11 (45.8%) of the 24 strains. Saa gene was present only one strains (4.2%). Toxin typing using reverse passive latex agglutination test showed the same result in VT 1. But it showed different result in VT 2. In antimicrobial susceptibility test, all isolates were sensitive to amikacin, amoxicillin/clavulanic acid, ciprofloxacin and colistin. Eighteen strains (75.0%) of 24 isolates showed the multi-resistant patterns with over 3 drugs. PFGE was performed after the genomic DNA of twenty four isolates was digested with Xba I. the 24 isolates showed 7 (A~G) PFGE type.
( Taek Hwan Lee ),( Ji Hee Kang ),( Jae Ok Seo ),( So Hyeon Baek ),( Sang Hyun Moh ),( Jae Kyoung Chae ),( Yong Un Park ),( Young Tag Ko ),( Sun Yeou Kim ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.1
We already reported that genetically engineered resveratrol-enriched rice (RR) showed to down-regulate skin melanogenesis. To be developed to increase the bioactivity of RR using calli from plants, RR was adopted for mass production using plant tissue culture technologies. In addition, high-pressure homogenization (HPH) was used to increase the biocompatibility and penetration of the calli from RR into the skin. We aimed to develop anti-melanogenic agents incorporating calli of RR (cRR) and nanoparticles by high-pressure homogenization, examining the synergistic effects on the inhibition of UVB-induced hyperpigmentation. Depigmentation was observed following topical application of micro-cRR, nano-calli of normal rice (cNR), and nano-cRR to ultraviolet B (UVB)-stimulated hyperpigmented guinea pig dorsal skin. Colorimetric analysis, tyrosinase immunostaining, and Fontana-Masson staining for UVB-promoted melanin were performed. Nano-cRR inhibited changes in the melanin color index caused by UVBpromoted hyperpigmentation, and demonstrated stronger anti-melanogenic potential than micro-cRR. In epidermal skin, nanocRR repressed UVB-promoted melanin granules, thereby suppressing hyperpigmentation. The UVB-enhanced, highly expressed tyrosinase in the basal layer of the epidermis was inhibited by nano-cRR more prominently than by micro-cRR and nano-cNR. The anti-melanogenic potency of nano-cRR also depended on pH and particle size. Nano-cRR shows promising potential to regulate skin pigmentation following UVB exposure.
Module level EMC verification method for replacement items in nuclear power plant
Hee-Taek Lim,Moon-Gi Min,Hyun-Ki Kim,Gwang-Hyun Lee,Chae-Hyun Yang Korean Nuclear Society 2023 Nuclear Engineering and Technology Vol.55 No.7
Internal replaceable electronic module substitutions can impact EMC (ElectroMagnetic Compatibility) qualification testing and results if EMC testing is conducted at the cabinet level. The impact of component substitutions on EMC qualification results therefore should be evaluated. If a qualitative evaluation is not adequate to ensure that the modified product will not impact the cabinet level EMC qualification results, a new qualification testing should be conducted. Component level retesting should be conducted under electromagnetically equivalent conditions with the cabinet level test. This paper analyzes the propagation of conducted susceptibility test waveforms in a representative cabinet and evaluates the impact of component substitutions on cabinet level EMC qualification results according to the location of the replacement items. A guideline for a qualitative evaluation of the impact of component substitutions is described based on the propagation of the conducted susceptibility test waveforms. A module level test method is also described based on an analysis of the shielding effectiveness of the cabinet.
Lee, Taek Hwan,Kang, Ji Hee,Seo, Jae Ok,Baek, So-Hyeon,Moh, Sang Hyun,Chae, Jae Kyoung,Park, Yong Un,Ko, Young Tag,Kim, Sun Yeou The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.1
We already reported that genetically engineered resveratrol-enriched rice (RR) showed to down-regulate skin melanogenesis. To be developed to increase the bioactivity of RR using calli from plants, RR was adopted for mass production using plant tissue culture technologies. In addition, high-pressure homogenization (HPH) was used to increase the biocompatibility and penetration of the calli from RR into the skin. We aimed to develop anti-melanogenic agents incorporating calli of RR (cRR) and nanoparticles by high-pressure homogenization, examining the synergistic effects on the inhibition of UVB-induced hyperpigmentation. Depigmentation was observed following topical application of micro-cRR, nano-calli of normal rice (cNR), and nano-cRR to ultraviolet B (UVB)-stimulated hyperpigmented guinea pig dorsal skin. Colorimetric analysis, tyrosinase immunostaining, and Fontana-Masson staining for UVB-promoted melanin were performed. Nano-cRR inhibited changes in the melanin color index caused by UVB-promoted hyperpigmentation, and demonstrated stronger anti-melanogenic potential than micro-cRR. In epidermal skin, nano-cRR repressed UVB-promoted melanin granules, thereby suppressing hyperpigmentation. The UVB-enhanced, highly expressed tyrosinase in the basal layer of the epidermis was inhibited by nano-cRR more prominently than by micro-cRR and nano-cNR. The anti-melanogenic potency of nano-cRR also depended on pH and particle size. Nano-cRR shows promising potential to regulate skin pigmentation following UVB exposure.
임채춘(Chae Chun Rhim),노성래(Sung Rae Roh),김동주(Dong Joo Kim),송민경(Min Kyung Song),이재성(Jae Sung Lee),주하경(Ha Kyong Joo),박윤희(Youn Hee Park),유기성(Ki Sung Ryu),한구택(Gu Taek Han),이종건(Jong Kun Lee),이준모(Joon Mo Lee) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.8
The malignant lymphomas are neoplastic transformation of cells that reside predominantly in lymphoid tissues. The two major variants of malignant lymphoma are non-Hodgkin's lymphoma and Hodgkin's disease. Although both of these tumors infiltrate reticuloendothelial organs, their biologic and clinical behaviors suggest that they are probably not related. More than 90% of all cases of non-Hodgkin's lymphomas are of B-cell derivation. This observation is based upon the expression of B-lineage-restricted antigens as well as clonal rearrangements of immunoglobulin heavy and light chain genes. The malignant lymphoma localized in uterine cervix is rare and characteristically symptom-free expressed. We experienced a case of malignant lymphoma originated from uterine cervix, so we report with a brief of literature.