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Glucose Oxidase가 척수지각신경절세포에 미치는 영향과 천마의 효과에 관한 연구
송호준,이용석,손영우,이강창,정종길,신민교,홍기연 대한본초학회 2002 大韓本草學會誌 Vol.17 No.2
Objectives : To clarify the cytotoxic effect of glucose oxidase(GO) and protective effect of gastrodiae Rhizoma (GR) on spinal sensory ganglion(DRG) neurons, neurotoxicity mediated by GO was measured by MTT assay and neurofilament enzymeimmuno assay(EIA). Methods : DRG neurons were cultured in the media containing various concentrations of GO for 3 hours. In addition, neuroprotective effects of GR, on GO-induced neurotoxicity in DRG neurons were examined after DRG neurons were preincubated with various concentrations of GR for 2 hours before 15mU/ml GO for 3 hours. Results : GO decreased remarkably cell viability in dependently in these cultures, and also RG increased cell viability and amount of neurofilament in DRG neurons damaged by GO. Conclusion : It is suggested that GO has toxic effect in cultured mouse DRG neurons, and also RG was effective in the protection of GO-induced neurotoxicity in these cultures.
송기용 충북대학교 컴퓨터정보통신 연구소 2001 컴퓨터정보통신연구 Vol.9 No.1
본 논문은 2의 보수표기 이진수에 대한 유사트리구조의 16-bit ×16-bit 승산기를 설계하고 이를 FPGA에 구현하였다. 분석결과 제안된 승산기는 Booth 배열승산기 또는 수정형 배열승산기보다 회로복잡도가 낮고 처리속도가 빠른 것을 확인하였다. This paper proposes a 16-bit × 16-bit multiplier for 2 twos-complement binary numbers with tree-like structure and implements it on a FPGA. The space and time complexity analysis shows that the 16-bit Tree-like multiplier represents lower circuit complexity and computes more quickly than both Booth arry multiplier and Modified array multiplier.
제지폐수처리용 생물고분자응집제를 생산하는 Bacillus sp. K-111의 배양특성조사
권기석,손용호,최선택,정석관,송숙희,김동걸 7개 국립대학교 환경연구 논문집 공동발행 위원회 2002 환경연구논문집 Vol.2 No.1
Flocculant-producing microorganisms were screened from obtained strains in the laboratory using a pulp-wastewater treatment as the flocculating agent. K-111 strain that had high flocculating activity among them was selected and identified as Bacillus sp. K-111 16s rDNA sequencing. The favorable medium for the production of flocculant was glucose 1.5%, NH_4NO_3 0.2%, tryptone 0.01%, K_2HPO_4 0.08%, KH_2PO_4 0.06%, CaCO_3 0.03%, MgSO_4·7H_2O 0.005%, MnSO_4 0.005% in 1 liter of D.W. at initial pH 7.0. The optimum culture temperature and pH were 30℃ and pH 7.0, respectively. the flocculating activity was observed most highly after 36 to 48 hr of cultivation at the optimum conditions. the flocculating activity of produced biopolymer on optimum conditions was about 2.5-fold higher than that of screening medium.
Design of an nonlinear schedule systolic array with sytem-level design language(SpecC)
Song, Gi-Yong 충북대학교 컴퓨터정보통신 연구소 2004 컴퓨터정보통신연구 Vol.12 No.3
A well-defined design methodology supported by a system-level design language plays an important role in managing the complexity of the design flow, especially at the system level. The SpecC is a powerful system-level design language which is developed to integrate the specification and the design phase in the SoC design process. This paper presents a design of a nonlinear systolic array on a SoC with SpecC, starting with specification model and then going through architecture exploration and communication synthesis steps.
Clinicopathological features of the intraductal papillary neoplasms of the intrahepatic bile duct
Gi-Woong Jang,Shin Hwang,Yong-Joo Lee,Ki-Hun Kim,Kwang-Min Park,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Sung-Gyu Lee 한국간담췌외과학회 2012 한국간담췌외과학회지 Vol.16 No.4
Backgrounds/Aims: This study is intended to investigate the clinicopathological features of the intraductal papillary neoplasms of the intrahepatic bile duct (IPNB), especially focused on malignant changes. Methods: From the institutional database of liver resection cases (Asan Medical Center, University of Ulsan College of Medicine), 18 patients who met the definition of IPNB were selected. They had undergone liver resection between February 2002 and October 2006; thus, the follow-up period was more than 5 years. Results: Of the 18 patients, 11 patients were male. Their mean age was 61.3±6.7 years. There were no differences between the non-malignant and malignant lesions, in the comparison of the CEA levels (5.6±2.7 vs.12.6±31.1 ng/ml, p=0.439) and the CA19-9 levels (29.2±34.7 vs.31.9±30.2 ng/ml, p=0.871). The common radiologic findings were: intraductal growing mass in 10; bile duct dilatation in 6; and saccular duct dilatation in 2. Left and right hepatectomies were performed in 15 and 3, respectively. Five patients showed benign lesions of IPNB, and 13 patients revealed malignant lesions of intraductal papillary adnocarcinoma or cholangiocarcinoma. All 4 patients with benign lesions survived for a mean period of 53 months without recurrence. In 13 patients with the malignant lesions, 1-year, 3-year, and 5-year survival rates were 100%, 84.6%, and 59.2%, respectively. Conclusions: We concluded that intrahepatic IPNB is a rare type of biliary neoplasm which includes a histological spectrum, ranging from benign disease to invasive malignancy. The long-term survival was anticipated after complete curative resection. (Korean J Hepatobiliary Pancreat Surg 2012;16:138-141)
Hyun Gi Kong(Hyun Gi Kong),Mee Kyung Sang(Mee Kyung Sang),Ju Hee An(Ju Hee An),Songhwa Kim(Songhwa Kim),Yong Ju Jin(Yong Ju Jin),Jaekyeong Song(Jaekyeong Song) 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.6
Bacterial wilt caused by Ralstonia solanacearum is considered one of the most harmful diseases of pepper plants. Recently, research on plant disease control through the rhizosphere microbiome has been actively conducted. In this study, the relationship with disease occurrence between the neighboring plant confirmed by analyzing the physicochemical properties of the rhizosphere soil and changes in the microbial community. The results confirmed that the microbial community changes significantly depending on the organic matters, P2O5, and clay in the soil. Despite significant differences in microbial communities according to soil composition, Actinobacteriota at the phylum level was higher in healthy plant rhizosphere (mean of relative abundance, D: 8.05 ± 1.13; H: 10.06 ± 1.59). These results suggest that Actinobacteriota may be associated with bacterial wilt disease. In this study, we present basic information for constructing of healthy soil in the future by presenting the major microbial groups that can suppress bacterial wilt.