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Gayoung Shin,Kwanghee Lee,Soyoun An,Jihyun Song,Narang Heo,Jiyoung Ra 大韓小兒齒科學會 2015 大韓小兒齒科學會誌 Vol.42 No.2
Endodontic management of an immature permanent tooth with dens invaginatus poses a challenge to efficient treatment planning for the clinicians. Because it is difficult to shape, disinfect, and seal the canal space effectively, teeth with complex root canal structures often require particularly extensive and thorough treatment approaches. The purpose of this case report was to share clinical insight from the results of short-term followups after regenerative endodontic treatment with a dens invaginatus. Two immature maxillary lateral incisors with Oehlers type I and III dens invaginatus and infected necrotic pulp were treated using regenerative endodontic procedures. For the type III dens invaginatus case, an unusual approach toward redesigning the complex internal structure was taken, in order to have sufficient infection control and sealing. Cone-beam computed tomography (CBCT) and a surgical operating microscope were used to aid visualization and treatment. As a result, regenerative endodontic treatment appears to be effective for managing immature permanent teeth with complex dens invaginatus, and can lead not only to clinical and radiographic resolution, but also increased thickness of the dentinal walls. 치내치를 동반한 미성숙 영구치의 근관치료를 성공적으로 수행하는 것은 치과의사에게 어려운 과제이다. 복잡한 형태의근관계는 근관 내부를 효과적으로 성형, 멸균, 충전하는 것이 어렵기 때문에 포괄적이고 철저한 치료계획을 수립하는 것이중요하다. 본 증례는 치내치를 동반한 감염된 미성숙 영구치를 가진 두명의 환자에게 재생형 근관치료를 시행하여 양호한 결과를 얻었기에 이를 보고하고자 한다. 감염된 괴사치수와 각각 Oehlers type I, type III 치내치를 포함하는 두개의 미성숙 상악 측절치에 재생형 근관치료가 시행되었다. 특히 Type III 치내치의 근관치료는 보다 효과적인 감염조절과 근관 충전을 위해 복잡한 근관 내부 구조를 재형성하는 드문 접근법을 이용하였다. 이 때, Cone-beam computed tomography (CBCT)와 미세 수술 현미경의 사용은 근관내부의 시각화 및 치료에 도움이 되었다. 결과적으로, 복잡한 형태의 치내치를 포함하는 미성숙 영구치의 재생형 근관치료는 임상적, 방사선학적 치유 뿐만 아니라치근 상아질 벽의 두께 증가를 가능하게하는 효과적인 치료 방법이 될 수 있을 것으로 생각된다.
( Shin-hye Yu ),( Soomin Kim ),( Yujin Kim ),( Seo-eun Lee ),( Jong Hyeok Park ),( Gayoung Cho ),( Jong-cheon Ha ),( Hahnsun Jung ),( Sang-min Lim ),( Kyuboem Han ),( Hong Kyu Lee ),( Young Cheol Kang 생화학분자생물학회 2022 BMB Reports Vol.55 No.3
Inflammation is one of the body’s natural responses to injury and illness as part of the healing process. However, persistent inflammation can lead to chronic inflammatory diseases and multi-organ failure. Altered mitochondrial function has been implicated in several acute and chronic inflammatory diseases by inducing an abnormal inflammatory response. Therefore, treating inflammatory diseases by recovering mitochondrial function may be a potential therapeutic approach. Recently, mitochondrial transplantation has been proven to be beneficial in hyperinflammatory animal models. However, it is unclear how mitochondrial transplantation attenuates inflammatory responses induced by external stimuli. Here, we isolated mitochondria from umbilical cord-derived mesenchymal stem cells, referred as to PN-101. We found that PN-101 could significantly reduce LPS-induced mortality in mice. In addition, in phorbol 12-myristate 13-acetate (PMA)-treated THP-1 macrophages, PN-101 attenuated LPS-induced increase production of pro-inflammatory cytokines. Furthermore, the anti-inflammatory effect of PN-101 was mediated by blockade of phosphorylation, nuclear translocation, and trans-activity of NFκB. Taken together, our results demonstrate that PN-101 has therapeutic potential to attenuate pathological inflammatory responses. [BMB Reports 2022; 55(3): 136-141]
Gayoung Lee,Jaehun Jeong,Jisu Choi,Yeyeon Kim,Sooyong Shin,Sungho Jeon,Moongyu Jang 한국자기학회 2021 한국자기학회 학술연구발표회 논문개요집 Vol.31 No.1
Electrical Cell-substrate Impedance System and Electrical Impedance Spectroscopy are the widely used methods in the field of biosensors for the monitoring of the status of cell. On the contrary, the usually used biosensors are bulky and hard to monitor in real time. In this work, temperature/impedance integrated sensors are manufactured using semiconductor process for the simultaneous monitoring of the temperature and impedance variations during the cell-drug reactions. The developed platinum thin film temperature sensor showed the inaccuracy less than ±0.05 ℃ and the MEMS process is adopted to enhance the temperature sensitivity. HeLa cancer cells and NIH 3T3 cells are grown on the biosensors and the drug reactions are monitored as a function of time and frequency. The impedance rapidly increase at the early stage and gradually decreased with time as a results of cell-drug reactions. Also, the temperature variations are monitored during the cell-drug reactions. The results are compared with the results by biological cell viability test on the conventional culture plates. The time and frequency dependent impedance signals are analysed in detail with the comparison between biological results.
Bifacial color realization for a-Si:H solar cells using transparent multilayered electrodes
Kim, Gayoung,Lim, Jung Wook,Shin, Myunghun,Yun, Sun Jin Elsevier 2018 SOLAR ENERGY -PHOENIX ARIZONA THEN NEW YORK- Vol.159 No.-
<P><B>Abstract</B></P> <P>Transparent hydrogenated amorphous silicon (a-Si:H) thin-film solar cells, in which the colors of the front and rear faces can be adjusted individually, were developed for implementation in building-integrated photovoltaic (BIPV) windows. The proposed ultrathin transparent multilayered electrodes (TMEs) are highly conductive and transparent, consisting of a bottom layer of gallium-doped zinc oxide (GZO), a thin metal layer of Ag, and an optoelectronic controlling layer (OCL) of GZO. They can be used for both the front and rear electrodes of transparent a-Si:H solar cells, and the resulting solar cells show a 5.0% average power conversion efficiency and 18.3% average transmittance. The various dual colors on the front and rear of the cell can be individually adjusted by changing the thickness of the OCL on each face of the TME, without significantly changing the efficiency. The cell colors were quantitatively investigated using the color coordinates in a chromaticity diagram based on the International Commission on Illumination (CIE; 1931) standard to show that the simulated and observed colors match well under both LED and fluorescent light sources. We also show that the observable color of the BIPV windows is determined by indoor and outdoor light sources, and dynamically varies as a function of illuminance of the light source as the day gradually progresses into night. This study helps to elucidate the color behavior of the BIPV windows and to develop a-Si:H BIPV windows that show various colors with stable electrical power generation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Development of transparent hydrogenated amorphous silicon (a-Si:H) solar cells. </LI> <LI> The colors independently controlled without seriously affecting the efficiency. </LI> <LI> The colors of solar windows considering indoor light illumination conditions. </LI> <LI> Quantitative analysis of colored solar cells using CIE 1931 diagram. </LI> </UL> </P>
Hyeju Han,Gayoung Shin,Ahyoung Jun,Taeok Park,Do-heungKo,Eunhee Choi,Youngsun Kim 대한재활의학회 2016 Annals of Rehabilitation Medicine Vol.40 No.1
Objective To examine the relation between the presence of penetration or aspiration and the occurrence of the clinical indicators of dysphagia. The presence of penetration or aspiration is closely related to the clinical indicators of dysphagia. It is essential to understand these relationships in order to implement proper diagnosis and treatment of dysphagia. Methods Fifty-eight poststroke survivors were divided into two groups: patients with or without penetration or aspiration. Medical records and videofluoroscopic swallowing examinations were reviewed. The occurrence of clinical indicators of dysphagia between two groups was analyzed with Cross Tabulation and the Pearson chi-square test (p<0.05).Results Poststroke survivors with penetration or aspiration had significantly high occurrences of delayed initiation of the swallow (p=0.04) and reduced hyolaryngeal elevation (p<0.01) than those without penetration or aspiration.Conclusion The results of this study indicate that delayed initiation of the swallow is a strong physiological indicator of penetration or aspiration during the oral stage of swallowing in poststroke survivors. For the pharyngeal stage of swallowing, hyoid and laryngeal elevation is a key event related to occurrence of penetration or aspiration. Clinical indicators should be investigated further to allow appropriate implementation of treatment strategies for stroke survivors.
윤효진(Yoon, Hyojin),신가영(Shin, Gayoung),배소영(Pae, Soyeong) 한국음성학회 2014 말소리와 음성과학 Vol.6 No.4
The study investigated the effects of reading intervention to enhance reading fluency for children from low-income families. The participants were 20 children from low-income families who are in grades 1 to 3. To qualify for participation in this study, all children had to score below 30 % ile on the Receptive vocabulary Test of the Expressive and Receptive Vocabulary Test or the Word reading fluency of the Korean Language-Based Reading Assessment. Participants were randomly assigned to the intervention (n=10) or control (n=10) group. The intervention group participated in the individualized intervention program using the guided repeated reading and the corrective feedback strategies. The results showed that participants in the intervention group performed better on reading fluency than those in the control group after participating in the intervention program. Specifically, guided repeated reading with corrective feedback strategies produced significant improvement on generalization to unpracticed passages as well as practiced passages. The results of this study suggest that guided repeated reading with corrective feedback is effective for enhancing reading fluency for children in Korea. Further study is needed in order to develop language-specific reading intervention.
Colored a-Si:H transparent solar cells employing ultrathin transparent multi-layered electrodes
Lim, Jung Wook,Kim, Gayoung,Shin, Myunghun,Yun, Sun Jin Elsevier 2017 Solar energy materials and solar cells Vol.163 No.-
<P><B>Abstract</B></P> <P>We fabricated hydrogenated amorphous silicon (a-Si: H) transparent solar cells using ultrathin transparent multi-layered electrodes (TMEs) as rear-side transparent electrodes for building-integrated photovoltaic (BIPV) windows. Each TME included a bottom layer, thin Ag layer, and optoelectronic controlling layer (OCL). The TMEs were experimentally designed to have high transparency and conductance. The fabricated a-Si:H transparent solar cells showed optimal performance with a 6.36% power-conversion efficiency and 23.5% average transmittance (500–800nm) when TMEs with a thickness less than 160nm were incorporated. We demonstrated that the reflection color of the cell could be tuned without serious loss of cell efficiency by varying the thickness of the OCL. The backside colors were predicted to be the coordinates on a CIE 1931 chromaticity diagram using the reflection spectrum from the cell and emission spectrum of a 50W LED light source. The developed a-Si:H transparent solar cells exhibited high efficiency and show feasibility for incorporating various colors in the photovoltaic and aesthetic functionalities of BIPV windows.</P>