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      • Development of Delayed Anaphylactic Reaction after Sugammadex Administration in the Post-Anesthesia Care Unit

        ( Gahee Kim ),( Junbum Lee ),( Sangho Lee ),( Jeong-hyun Choi ) 경희대학교 경희의료원 2022 慶熙醫學 Vol.37 No.1

        Sugammadex induced anaphylactic reaction is very urgent event as it is usually not anticipated in the advance. The incidence of anaphylactic reaction due to sugammadex is rare, 0.0039% to 0.3%, but it can occur even if there is no previous allergy history, and it often occurs after extubation, so immediate diagnosis and treatment are essential. This report presents a 70-year-old woman who had no previous exposure to sugammadex and allergy history and scheduled to undergo posterior lumbar interbody fusion L4-S1 to treat lumbosacral spondylolisthesis. Anesthesia via propofol, inhalational gas, remifentanil and rocuronium was used. The operation under general anesthesia went well without any problems The patient was administered sugammadex to reversal neuromuscular block, and delivered to post-anesthesia care unit (PACU). After arrival at PACU, she had anaphylactic reaction and received appropriate treatment including epinephrine. She discharged without any complications 6 weeks days after the surgery.

      • Effect of Al2O3 Nano-Filler on Properties of Alkali/Alkaline-Earth Borosilicate Glass Composite Sealants.

        Lee, Dong Bok,Kim, Kwang-Joong,Yoo, Gahee,Park, Sung,Lee, Jae Chun American Scientific Publishers 2015 Journal of Nanoscience and Nanotechnology Vol.15 No.7

        <P>The effect of adding Al2O3 nano-filler (5 and 10 vol%) to two different alkali/alkaline-earth borosilicate glass sealants, particularly on the viscosity and electrical characteristics of the glass composite sealants, was investigated to improve the cyclic sealing performance. The effects of the filler and base glass composition on the viscosities, electrical conductivities, and phase transformations of the sealants were investigated. The glass viscosity was decreased by replacing 20 mol% SrO with alkali and zirconium oxide in a base alkaline-earth glass. Alumina filler increased the high-temperature electrical conductivities, as well as the viscosities, of the heat-treated glass composite sealants. The replacement of 20 mol% SrO with alkali and zirconium oxide in the base alkaline-earth glass decreased the electrical conductivity of the heat-treated glass containing Al2O3 nano-filler.</P>

      • KCI등재

        Characterization of Ceftriaxone-Resistant Haemophilus influenzae Among Korean Children

        Lee Sanghoon,Kim Gahee,Kim Jung Hwa,Kim Mi-Na,Lee Jina 대한의학회 2024 Journal of Korean medical science Vol.39 No.15

        Background: Haemophilus influenzae is a frequently encountered pathogen responsible for respiratory tract infections in children. Following the detection of ceftriaxone-resistant H. influenzae at our institution, we aimed to investigate the resistance mechanisms of ceftriaxone in H. influenzae, with a particular focus on alterations in penicillin-binding protein 3 (PBP3) and β-lactamase production. Methods: Among H. influenzae isolates collected at Asan Medical Center Children’s Hospital from March 2014 to April 2019, ceftriaxone-resistant strains by the disk-diffusion test were included. Ceftriaxone minimum inhibitory concentrations (MICs) were determined using the E-test according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines. The presence of β-lactamase was assessed through cefinase test and TEM-1/ROB-1 polymerase chain reaction (PCR). PBP3 alterations were explored via ftsI gene sequencing. Results: Out of the 68 collected strains, 21 exhibited resistance to ceftriaxone in disk diffusion tests. Two strains were excluded due to failed subculture. Among 19 ceftriaxoneresistant H. influenzae isolates, eighteen were non-typeable H. influenzae, and twelve were positive for TEM-1 PCR. Isolates were classified into groups II (harboring only N526K, n = 3), III (N526K+S385T, n = 2), III+ (S385T+L389F+N526K, n = 11), and III-like+ (S385T+L389F+R517H, n = 3) according to the PBP3 alteration pattern. With a median ceftriaxone MIC of 0.190 mg/L (range, 0.008–0.750), the median ceftriaxone MIC was the highest in group III-like+ (0.250 mg/L), followed by groups III+ (0.190 mg/L), III (0.158 mg/L), and II (0.012 mg/L). All three strains belonging to group II, which did not harbor the S385T substitution, had ceftriaxone MICs of ≤ 0.125 mg/L. Conclusion: The emergence of ceftriaxone-resistant H. influenzae with ceftriaxone MIC values of up to 0.75 mg/L was observed even in children in South Korea, with most associated with S385T and L389F substitutions. The N526K mutation alone does not significantly impact ceftriaxone resistance. Further large-scale studies are essential to investigate changes in antibiotic resistance patterns and factors influencing antibiotic resistance in H. influenzae isolated from pediatric patients in Korea.

      • KCI등재

        Trends in behavioral management techniques for dental treatment of patients with autism spectrum disorder: a 10-year retrospective analysis

        Gahee Son,Sohee Oh,Jaehee Lee,Saeromi Jun,Jongbin Kim,Jongsoo Kim,Joonhaeng Lee,Miran Han,Jisun Shin The Korean Dental Society of Anesthsiology 2024 Journal of Dental Anesthesia and Pain Medicine Vol.24 No.3

        Background: Patients with autism spectrum disorder (ASD) present challenges in dental treatment cooperation owing to deficits in communication skills and social interaction. Behavioral guidance, sedation, and general anesthesia may be employed to ensure the quality of dental care for individuals with ASD. This study aimed to examine the trends in dental treatment for patients with ASD who visited the Department of Pediatric Dentistry at Dankook University Jukjeon Dental Hospital, an oral health center for the disabled in the Gyeonggi region, over the past 10 years. Methods: This study utilized the order communication system to gather data on sex, age, cooperation level, number of quadrants treated, and administration of sedation or general anesthesia for patients with ASD who visited the Department of Pediatric Dentistry at Dankook University Jukjeon Dental Hospital between January 2013 and December 2022. Results: The total number of patients with ASD increased annually, possibly due to an increase in ASD prevalence and the hospital's designation as a center for disabled oral health. General anesthesia was predominant before 2017, with a shift towards N<sub>2</sub>O-O<sub>2</sub> sedation. The most common age group for sedation or general anesthesia was 6-9 years, with a higher prevalence in males than in females. Notably, N<sub>2</sub>O-O<sub>2</sub> and midazolam sedation resulted in better cooperation and fewer treated teeth than general anesthesia. Conclusion: This study highlights the evolving trends in dental treatment for individuals with ASD, indicating a shift towards outpatient methods, particularly N<sub>2</sub>O-O<sub>2</sub> sedation. The sex distribution aligns with national statistics, emphasizing a higher prevalence of ASD in males than in females. These findings underscore the need for further research to establish evidence-based guidelines for optimal dental care strategies tailored to the unique needs of individuals with ASD.

      • KCI등재후보

        온도변화와 촉매조건에 따른 아역청탄과 아역청탄으로부터 추출한 초청정탄을 이용한 가스화 반응성 비교

        이가희(Gahee Lee),윤상필(SangPhil Yoon),전영신(YongShin Jeon),김형택(Hyung-Taek Kim) 한국에너지기후변화학회 2011 에너지기후변화학회지 Vol.6 No.2

        Coal is spotlighted as a top priority energy resource which will replace oil. Coal gasification can reduce amount of carbon dioxide(CO<SUB>2</SUB>), sulfur oxides(SOx) and nitrogen oxides(NOx). Also, it produces mono dioxide(CO) and Hydrogen(H<SUB>2</SUB>). However, typical-type coal gasification technology is required huge amount of energy at high temperature over 1000℃. Therefore, catalyst(K<SUB>2</SUB>CO<SUB>3</SUB>) is added to decrease operation temperature and reduce amount of energy. In this experiment, Roto ultra clean coal(UCC) and Roto original coal(OC) are used. And coal char is produced for this experiment. The experiment is progressed with 1g of coal char with potassium carbonate(K<SUB>2</SUB>CO<SUB>3</SUB>) under flowed 500ml/m of steam(H<SUB>2</SUB>O) as a reactant and 2000ml/min of nitrogen as carrier gas. With this condition, it is progressed for 1hr under different designated temperature(600, 700, 800℃) and different catalyst conditions. From those experiments, the carbon conversion ratio is calculated and compared the gasification reactivity

      • KCI등재
      • KCI등재

        고객 유형 맞춤 캠핑용 하우징 서비스디자인 개발 연구

        이지혜 ( Lee Jihye ),권기제 ( Kwon Kije ),조진희 ( Jo Jinhee ),박성흠 ( Park Sung-hum ),유동균 ( Yu Dong Kyun ),이가희 ( Lee Gahee ) 커뮤니케이션디자인학회 2022 커뮤니케이션 디자인학연구 Vol.78 No.-

        본 연구는 한국디자인진흥원 R&D연구의 일환으로 최근 급격히 성장하고 있는 캠핑 산업에 있어서 주로 캠핑카로 인식되는 캠핑용 하우징 제품에 대한 고객의 실제적 니즈와 라이프스타일을 통한 서비스 디자인 전략을 연구하는 것을 목적으로 하였다. 연구 결과, 대부분의 캠퍼들은 캠핑준비 및 캠핑과정에 수반되는 번거로움을 해소하기 위해 캠핑카를 구매하는 것으로 드러났다. 이와 같은 캠핑용하우징 제품과 서비스에 대한 소비자의 주요니즈는 다음과 같다. 첫째, 효율적인 내부 공간 구성에 대한 수요가 파악되었다. 고객들에게는 라이프스타일과 성향에 따라 자유롭게 공간을 구성할 수 있는 제품을 필요로 한다. 둘째, 개성 표현을 할 수 있는 커스터마이징에 대한 수요가 파악되었다. 다시 말해 고객들은 개인의 성향과 라이프스타일에 맞는 제품을 구매하길 바란다. 따라서 외관 디자인 및 내부 인테리어 소재 등을 선택할 수 있도록 다양한 옵션 제공과 용도별 라인업 제품이 필요하다. 셋째, 구매과정 및 사후 관리에 있어서의 번거로움이 해소되어야 한다. 본 연구에 진행한 사용자 설문조사 결과, A/S 과정이 번거롭고, 기술 개발에 치중되어 있는 중소기업은 많은 부분 고객응대서비스에 개선이 필요하다는 답변이 다수 나타났다. 즉, 보다 고객 친화적인 서비스 제공 전략이 필요한 것이다. 따라서 고객의 번거로움이 최소화될 수 있는 통합 서비스가 제공 되어야 제품 사용 시 중도 이탈 없이 지속적인 고객층 확보가용이 할 것으로 보인다. 이와 같은 연구결과를 토대로 본 연구는 최종적으로 핵심 시나리오 5건과 서비스 플로우를 설계하여 제안하였다. 이는 향후 캠핑카 관련 서비스 개발, 혹은 고객 성향과 라이프스타일을 고려한 제품개발 시 유용하게 활용될 수 있을 것으로 기대한다. As part of the Korea Institute of Design Promotion's R&D study, the purpose of this research was to study the strategy of service design through the customer's practical needs and lifestyle for camping housing products, which are mainly recognized as camping cars in the recent rapidly growing camping industry. This studies have shown that most campers purchase camping cars to relieve the hassles accompanied by camping preparation processes. The main needs of consumers like this for such camping housing products and services are as follows. First, the demand for efficient internal space composition was identified. Customers need products that can freely organize the space according to their lifestyle and inclination. Second, the demand for customization that can express individuality was identified. In other words, customers want to purchase products that suit their individual tendencies and lifestyles. Therefore, it is necessary to provide various options and line-up products for each purpose, so that exterior design and interior materials can be picked. Third, the hassles of the purchasing process and follow-up management must be resolved. As a result of the user survey conducted in this study, many small and medium-sized enterprises focused on the technology developments & cumbersome in their after-sales service process have been replied in the majority that many parts of them need the improvement of customer service. In other words, a more customer-friendly service provision strategy is needed. Therefore, it is expected that it will be possible to continuously secure a customer base without leaving in the middle of using the product only when the integrated services that can minimize customer hassle are provided. This study finally designed and proposed five key scenarios and service flows based on these research results. This is expected to be utilized usefully in the future when developing camping car-related services or developing products that take into account customer tendencies and lifestyles.

      • General Anesthesia of a Patient with Charcot-Marie-Tooth Disease

        ( Junbum Lee ),( Gahee Kim ),( Sangho Lee ),( Jeong-hyun Choi ) 경희대학교 경희의료원 2022 慶熙醫學 Vol.37 No.1

        Charcot-Marie-Tooth (CMT) disease is a hereditary motor and sensory neuropathy of the peripheral nervous system. The initial presentation is usually foot drop or muscle wasting of the distal part of the leg. The symptom eventually progresses to atrophy of respiratory muscles, vocal cord and diaphragm. CMT patients require special caution during the general anesthesia. CMT disease can cause malignant hyperthermia, respiratory insufficiency and hyperkalemia during anesthesia. This report presents a 50-year-old man who has been diagnosed CMT disease and scheduled to undergo anterior cervical discectomy and fusion to treat cervical spinal stenosis. Propofol and remifentanil were used for the total intravenous anesthesia, and rocuronium was used for muscle relaxant purpose. Several intraoperative monitoring methods were performed to proceed the anesthesia safely, and the patient was discharged without any complications 5 days after the surgery. This case report with comprehensive literature review investigates possible adverse events and special cautions during the general anesthesia of CMT patients, and discusses adequate intraoperative monitoring to avoid such problems.

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