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세균 배양액과 반응한 Lactobacillus plantarum의 생장속도 및 항균 활성에 대한 연구
하은미 ( Eunmi Ha ) 한국미생물생명공학회(구 한국산업미생물학회) 2015 한국미생물·생명공학회지 Vol.43 No.3
In this study, L. plantarum, when reacting with the culture media of potential pathogenic bacteria, exhibited an increase in growth rate and antimicrobial activity. In order to examine the characteristics and the nature of the reaction with the bacteria, this study carried out experiments involving culturing the test bacteria in M9 minimal media. Subsequently, the supernatant was incrassated by the decompression-drying method. Through colony forming unit assay, it was confirmed that L. plantarum had the function of growth inhibition to various bacteria. After culturing L. plantarum with bacterial media, the growth rate of L. plantarum was measured by absorbance (OD600), the results showed that the growth rate (E. coli treatment group: OD600 = 0.848, S. typhimurium treatment group: OD600 = 0.848) increased, as compared with the non-treated control group (OD600 = 0.48). In contrast, the concentrate itself did not induce the growth of L. plantarum. These results were observed as a universal phenomenon of the Lactobacillus species. Moreover, the increase in antimicrobial activity was observed in L. plantarum, which reacted with the culture media of E. coli and S. typhimurium, through a disc diffusion assay, and the result of growth inhibition against various bacteria was induced. Finally, based on the analysis results of the characteristics of bacteria culture media, which increased the growth rate of L. plantarum and antibacterial activity, the bacterial media had a tolerance for catabolic enzymes, pH 28 and heat. Therefore, this substance can be said to be a small molecule which is highly stable under various conditions.
( Eunmi Jeon ),( Joseph Ha ) 서암순창장학회 2016 Journal of Marketing Thought Vol.2 No.4
Interfirm strategies, such as skill of communication or control, structure and regulate the conduct of parties in ex-change relationships. Similarly, collaborative communication can be used to create an atmosphere of mutual support, thereby creating volitional compliance between partners. We developed a model that addresses the interrelation-ships of frequency and communication and examined the effects of collaborative communication on channel out-comes across various levels of communication. Especially, we proposed that regional clusters enhance the relation-ship of communications, which in turn has a positive effect on network embeddedness. Based on survey data col-lected from participants that work in regional clusters, the findings indicate that when the levels of collaborative communication are high, the effect of collaborative communication on outcomes is stronger.
Junghee Ha,Hey Jung Jun,신혜원,Ick-Joong Chung,Eunmie Park,Sung Kil Min,EunJooKim 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.2
Objective: This study aimed to investigate whether maternal negative affectivity (MNA) moderates the effect of genetic polymorphism of SLC6A4 on behavior problems in children. Methods: Study participants comprised 143 preschoolers and their mothers from South Korea. The Childhood Behavior Checklist and Emotionality, Activity, and Sociability adult scale were used to measure child behavior and maternal affectivity. DNA from saliva was genotyped to determine serotonin transporter polymorphism. Results: MNA appeared to exert effects in externalizing (b =5.78, p<0.001) and internalizing problems (b =6.09, p< 0.001). Interaction between SLCA4 polymorphism and MNA showed effects on externalizing (b =−7.62, p<0.01) and internalizing problems (b =−9.77, p<0.01). Children with two short alleles showed considerable differences in both externalizing and internalizing problems according to MNA; however, children with one short allele or none showed relatively few differences in behavior problems due to maternal affectivity. Conclusion: The effect of SLC6A4 polymorphism on child behavior seemed to be moderated by MNA. In addition, the impact of MNA was found to vary based on a child’s genetic risk. High MNA may trigger the risk allele while low MNA causes the risk allele to illicit less behavior problems. Children with two short variants of the SLC6A4 gene may benefit from intervention that modulates MNA.
원장원,Eunmi Ha,Eunjin Jeong,김미지,Juhyun Park,Ja Euk Baek,Sungouk Kim,Sung Bae Kim,Jihun Roh,Jee Hye Choi,Seung Youn Jeon,Heeeun Jung,Daehyun Lee,Yuri Seo,Hyungeun Shin,Heesun Kim 대한노인병학회 2021 Annals of geriatric medicine and research Vol.25 No.1
The World Health Organization (WHO) recently endorsed the proposal for a Decade of Healthy Ageing (2020–2030). The WHO defines “healthy aging” as “the process of developing and maintaining the functional ability that enables wellbeing in older age.” Among the strategies for the Decade of Healthy Ageing, the WHO has suggested enhancing intrinsic capacity, promoting functional ability, and implementing the Integrated Care for Older People (ICOPE) package. The WHO has defined steps for ICOPE evaluation and scale-up and is performing a prospective study in 2–3 countries (low and middle income, high income) to test its feasibility in 2021–2022 and a multinational randomized study to validate its clinical efficacy and effectiveness in 2022–2024. Intrinsic capacity and frailty represent two faces of the same coin, with one indicating the reserves of the individual and the other indicating the deficits that accumulate with age. The Integrated Care of Older Patients with Frailty in Primary Care (ICOOP_Frail) study is the first integrated care program for frailty or functional decline in primary care in Korea. The results suggest that the ICOOP_Frail study can be utilized as a reference for ICOPE studies in Korea or at least to provide important findings for the forthcoming ICOPE implementation study in Korea.
Junghyun Park,YeongSu Ha,Seung-Ho Lee,Eunmi An 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
In Korea, extensive industry-academia-research research has already established many facilities and technologies for materials and chemical experiments on non-radioactive substances. However, few facilities have been built to analyze the physical and chemical properties of substances irradiated through neutron irradiation. Korea is planning to decommission Kori-1 and Wolsong-1 in 2027. Extensive analysis of low-level and intermediate-level materials is required to begin decommissioning these nuclear power plants. The material’s composition and level can be identified by analyzing the structure’s characteristics, and a cutting and decontamination plan can be established based on this. In addition, by conducting a nuclide analysis on the waste generated after cutting, suitability for disposal can be secured, and stable treatment can be performed. Accordingly, the Korea Decommissioning Research Institute (KRID) plans to secure infrastructure (hot cells) to analyze the characteristics of intermediate-level decommissioning waste. The goal is to secure high-dose/high-radiation decommissioning waste processing technology through Korea’s first intermediate-level hot cell, support domestic nuclear power plant decommissioning projects, and secure and verify procedures related to nuclide analysis of intermediate-level using hot cells. In addition, by possessing these material properties and nuclide analysis technology, KRID can have a foundation to conduct continuous research on low- and intermediate-level radioactive materials and decommissioning. The purpose of KRID’s establishment is to use this foundation in the future to improve the technological level of the nuclear industry as a whole through linkage between industry, academia, and research institutes.
Seung-Ho Lee,Yeong Su Ha,Junghyun Park,Eunmi An 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
Recently, the nuclear decommissioning and environmental restoration industries has significantly attracted as a new industry field due to the decision to decommission the KORI#1 and WOLSONG #1 nuclear power plant. In order to dispose of the decommissioning radioactive wastes generated during nuclear decommissioning, proper analysis is required, and disposal decisions are determined based on the analysis results. When dismantling a nuclear power plant, a few thousand of tons decommissioning waste are produced, so these require analysis for proper disposal. Therefore, a radionuclide facility for decommissioning waste analysis is essential for the disposal of the large quantities of decommissioning waste generated during nuclear power plant decommissioning. Korea Research Institute of Decommissioning (KRID) was established radionuclide analysis facilities to address above issues and support nuclear power plant decommissioning projects. The plan is to perform classification by type and radionuclide for all waste produced during nuclear power plant decommissioning and to support the disposal of radioactive wastes. In addition, we plan to establish validation methods for samples where verification methods are not established, in order to conduct efficient analysis and management. In this presentation, we will introduce the radionuclide facility currently under construction at KRID and present the space design, equipment layout, and utilization plans.