Impact of nano silver composite structure on cadmium neurotoxicity in albino rats

El-Sherbiny Emad Mohamed,Abdel-Gawad Eman Ismail,Osman Hala Fawzy 한국응용생명화학회 2022 Applied Biological Chemistry (Appl Biol Chem) Vol.65 No.6

The present study was planned to investigate the possible therapeutic effects of silver/hydroxyapatite nanocomposite (nAg/HAp) on neurotoxicity induced by cadmium chloride ( CdCl2) in albino rats. The nanocomposite has been formulated by a chemical route and characterized by scanning electron microscope (SEM), Transmission Electron Microscopy (TEM), and energy-dispersive X-ray Analysis spectroscopy (EDAX). A population of rats was randomly assorted into three groups; the animals were subjected to intraperitoneal CdCl2 administration every 2 days at a dose level of 1.0 mg/kg b.wt. for 3 months while the treatment with nAg/HAp was performed via intravenous injection at a dose level of 50 mg/kg b,wt. once a week for 4 weeks. Quantitative DNA fragmentation and biochemical analysis including the content of γ-aminobutyric acid (GABA), noradrenaline (NA), dopamine (DA), caspase-3, calmodulin (CaM), calcium adenosine 5′-triphosphatase ( Ca++ATPase), tau protein, glutathione (GSH) and malondialdehyde (MDA) were measured in brain tissue. The results revealed the potent efficacy of nAg/HAp in attenuating DNA fragmentation and partially recovering most of the investigated parameters manifested by a significant elevation in GABA, NA, DA, Ca++ ATPase, and GSH levels and a decrease in tau protein, caspase-3, CaM and MDA tissue content in comparison with Cd—intoxicated groups. Accordingly, the synthesized nAg/HAp at the selected dose can be used as a biosafe intravenous injection in neurodegenerative diseases. The present study was planned to investigate the possible therapeutic effects of silver/hydroxyapatite nanocomposite (nAg/HAp) on neurotoxicity induced by cadmium chloride (CdCl 2 ) in albino rats. The nanocomposite has been formulated by a chemical route and characterized by scanning electron microscope (SEM), Transmission Electron Microscopy (TEM), and energy-dispersive X-ray Analysis spectroscopy (EDAX). A population of rats was randomly assorted into three groups; the animals were subjected to intraperitoneal CdCl 2 administration every 2 days at a dose level of 1.0 mg/kg b.wt. for 3 months while the treatment with nAg/HAp was performed via intravenous injection at a dose level of 50 mg/kg b,wt. once a week for 4 weeks. Quantitative DNA fragmentation and biochemical analysis including the content of γ-aminobutyric acid (GABA), noradrenaline (NA), dopamine (DA), caspase-3, calmodulin (CaM), calcium adenosine 5′-triphosphatase (Ca ++ ATPase), tau protein, glutathione (GSH) and malondialdehyde (MDA) were measured in brain tissue. The results revealed the potent efficacy of nAg/HAp in attenuating DNA fragmentation and partially recovering most of the investigated parameters manifested by a significant elevation in GABA, NA, DA, Ca ++ ATPase, and GSH levels and a decrease in tau protein, caspase-3, CaM and MDA tissue content in comparison with Cd—intoxicated groups. Accordingly, the synthesized nAg/HAp at the selected dose can be used as a biosafe intravenous injection in neurodegenerative diseases.

Hepatitis C Virus Associations with Non Hodgkin's Lymphoma: Insights on Inflammation/Angiogenesis and CD Markers

El-Maadawy, Eman A,Talaat, Roba M,Sadek, Rawia F,El-Sherbini, Sherif M,Abdel-Bary, Naser,Abdel-Aziz, Amal A Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.9

We aimed to investigate any association between hepatitis C virus (HCV) infection and non-Hodgkin's lymphoma (NHL) in the view of cytokines that control inflammation/angiogenesis and their correlation with certain CD markers. NHL patients with or without HCV infection were studied. CD5, CD30, CD3, CD20 and CD45 were immunohistochemically evaluated. Plasma levels of vascular endothelial and platelet derived growth factors (VEGF, and PDGF), tumor necrosis factor (TNF-${\alpha}$), transforming growth factor (TGF-${\beta}$), interleukin-6 (IL-6), IL-8, IL-4, IL-12 and interferon gamma (IFN-${\gamma}$) were detected by enzyme-linked immunosorbent assay (ELISA). HCV+ve NHL patients showed a significant reduction in VEGF, PDGF, IFN-${\gamma}$, CD5 and CD45 and a significant increase in IL-12 and IL-8. In conclusion, there was a significant change in cytokine secretion and expression of CD markers in HCV+ve NHL patients. Based on our results, HCV infection in NHL patients requires more in-depth investigations to explore any role in lymphoma progression.

Carbon nanotube antennas analysis and applications: review

El-sherbiny, Sh.G.,Wageh, S.,Elhalafawy, S.M.,Sharshar, A.A. Techno-Press 2013 Advances in nano research Vol.1 No.1

Carbon nanotube characterized by additional inductive effect as compared with the traditional conductors like copper wires of the same size. Consequently, carbon nanotubes have high characteristic impedance and slow wave propagation in comparison with traditional conductors. Due to these characteristics, carbon nanotubes can be used as antenna. In view of this, we describe and review the present research progress on carbon nanotube antennas. We present different analysis models and results which are developed to investigate the characteristics of CNT antennas. Then we conclude by summarizing the characteristics of CNT antennas and specifying the operating frequency limit.

A New Algorithm for Segmentation and Classification of Bilingual Image Documents

Ahmed El Sherbini,Nadia H. Hegazi,Amel M. Abdein 한국통신학회 1993 Asia-Pacific Conference on Communications Vol.2 No.2

Thermal-induced Residual Stresses and Distortions in Friction Stir Welds - A Literature Review

Mohamed H. El-Moayed,Ahmed Y. Shash,Mahmoud Abd Rabou,Mahmoud G. El-Sherbiny 대한용접·접합학회 2021 대한용접·접합학회지 Vol.39 No.4

Friction Stir Welding (FSW) is a solid-state welding technique that uses the heat generated from friction to assemble a wide variety of materials. Irrespective of having a lower heat input as compared to conventional welding techniques, friction stir welds are still prone to significant thermal-induced stresses and distortions owing to the uneven heating and cooling cycles that a weld goes through. Surprisingly, not several reviews have addressed both the residual stresses and distortions of friction stir welds despite their crucial impact on the weld performance. Therefore, the current paper reviews their development, their correlation with process parameters, and ways to reduce them. Moreover, it explains the current status of process modeling and research gaps in the area of interest.

Efficient Coding Scheme for Digital Half-Toned Images

Ahmed M. El-Sherbini 한국통신학회 1993 Asia-Pacific Conference on Communications Vol.2 No.2

Mode II Fracture Toughness of Hybrid FRCs

H. S. S. Abou El-Mal,A. S. Sherbini,H. E. M. Sallam 한국콘크리트학회 2015 International Journal of Concrete Structures and M Vol.9 No.4

Mode II fracture toughness (KIIc) of fiber reinforced concrete (FRC) has been widely investigated under various patterns of test specimen geometries. Most of these studies were focused on single type fiber reinforced concrete. There is a lack in such studies for hybrid fiber reinforced concrete. In the current study, an experimental investigation of evaluating mode II fracture toughness (KIIc) of hybrid fiber embedded in high strength concrete matrix has been reported. Three different types of fibers; namely steel (S), glass (G), and polypropylene (PP) fibers were mixed together in four hybridization patterns (S/G), (S/PP), (G/PP), (S/G/PP) with constant cumulative volume fraction (Vf) of 1.5 %. The concrete matrix properties were kept the same for all hybrid FRC patterns. In an attempt to estimate a fairly accepted value of fracture toughness KIIc, four testing geometries and loading types are employed in this investigation. Three different ratios of notch depth to specimen width (a/w) 0.3, 0.4, and 0.5 were implemented in this study. Mode II fracture toughness of concrete KIIc was found to decrease with the increment of a/w ratio for all concretes and test geometries. Mode II fracture toughness KIIc was sensitive to the hybridization patterns of fiber. The (S/PP) hybridization pattern showed higher values than all other patterns, while the (S/G/PP) showed insignificant enhancement on mode II fracture toughness (KIIc). The four point shear test set up reflected the lowest values of mode II fracture toughness KIIc of concrete. The non damage defect concept proved that, double edge notch prism test setup is the most reliable test to measure pure mode II of concrete.

Changing in the Epidemiology of Tinea Capitis among School Children in Egypt

( Rasha H. Bassyouni,),( Naglaa A. El-sherbiny ),( Talal A. Abd El Raheem ),( Basma H. Mohammed ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.1

Background: Tinea capitis remains a prevalent health problem among school-aged children. Objective: To estimate the prevalence of tinea capitis among primary school students, in Fayoum, Egypt with identification of etiological agents in both public and private primary schools. Methods: A cross-sectional study was conducted in twelve primary schools. The students were selected from different grades with a total number of 12,128 students. Hair and scalp were clinically examined for any lesions that may suspect tinea capitis and mycological samples were collected for direct microscopy and culture. Results: The prevalence of tinea capitis in the study group was 0.4% and higher in public than private schools (73.5% versus 26.5% respectively). Boys were more affected than girls with boy to girls` ratio 5:1. Intrafamily history of infection was present in 40.8% of tested group while 51% showed low social standard profile. Mycological culture revealed that Microsporum canis was the predominant isolated organism followed by M. audouinii (52% and 36% respectively). Conclusion: M. canis is replacing Trichophyton violaceum as an etiology for tinea capitis in Egypt with lower prevalence rate than reported previously. (Ann Dermatol 29(1) 13∼19, 2017)

Effectiveness of dredging and drains’ treatment on water quality of Rosetta branch

Mohie Eldin M. Omar,Mohamed A. Ghareeb,Shaimaa El Sherbini 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.1

Rosetta Branch of Nile River in Egypt receives drainage water from five agricultural drains deteriorating its water quality. Since the branch is used for irrigation and municipal purposes, its water quality should be enhanced. Hence, the current paper aimed at providing the most effective intervention to improve the branch water quality. Preventing drainage disposal was excluded due its significance to downstream users. The paper investigated the impacts of drains" treatment and branch dredging on hydrodynamics and water quality. The branch was numerically simulated using HECRAS model, and calibrated using measured water levels and quality parameters. The paper selected constructed wetlands as the most suitable method for drainage treatment based on conditions of study area. SUBWET model predicted optimal designs of wetlands achieving the desired treatment efficiency. SUBWET model was calibrated with experimental wetlands at Delta Barrage. Results showed that 1-m dredging dropped water surface elevations by 22 to 50 cm. Dredging had no significant changes in the backwater zone of Edfina Barrage at the branch end except for the maximum flow case. Simulation of dissolved oxygen and ammonium showed that dredging and treatment improved water quality. Drains’ treatment by constructed wetlands with selected designs was much more effective than dredging.