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Climate Change, Water Related Hazards and Disasters: Challenge, Mitigation and Policy in Ethiopia
Dereje Birhanu Mitiku,Hyeonjun Kim,Ilpyo Hong,Sanghyun Park 한국방재학회 2015 한국방재학회 학술발표대회논문집 Vol.14 No.-
According to a recent analysis of NASA, the year 2014 now ranks as the warmest on record since 1880. Africa is widely held to be highly vulnerable to future climate change related hazards, and Ethiopia is often cited as one of the most extreme examples. The country’s economy is highly exposed to climate variability and extremes and the nature of agriculture, primarily rain-fed is sensitive to fluctuations in rainfall, which forms the basis of the economy supporting roughly 42% GDP and 85% employment. Wahlström M (2009) reported that over the last two decades (1988-2007), 76% of all disaster events were hydrological, meteorological or climatological in nature. In this review, a great concern is given for extreme conditions (flood and drought) particularly climate change related hazards and tries to look at the challenges, mitigation and policies. Climate change, drought and flood will continue to be a primary concern for many Ethiopian and even agricultural production and water supplies will become more severely diminished. Starting from 1970-1996 droughts and the resulting food shortage have affected millions and cause for the death of a significant number of people and in 2009 Ethiopia has experienced a delay in the main rainy season, particularly in northeastern areas, resulting in 50-70 % of agricultural land being sown for cropping. Ethiopia has also experienced a major flood in 1988, 1993, 1994, 1995, 1996 and 2006 and climate change, including extreme events like drought and flood affected areas will likely become more widely spread. Recently, flash floods affected big cities, including Addis Ababa and Dire Dawa (death of 300 people) and result in considerable damage to lives, livelihoods and property. Despite the hugely damaging effect that natural and man-made disasters have on Ethiopia’s economic development, little is done to prevent them. There are significant challenges to reduce climate change related hazards, but linking of climate change adaptation with disaster risk reduction and effective strategies to prevent hazards from becoming disasters and managing those disasters that do occur would make a lasting contribution to the quality of life and sustainable livelihoods. Several factors contribute to Ethiopia’s high vulnerability to disasters, but here the authors will focus on institutional frameworks and policy. There are several NGO and governmental climate change actors in Ethiopia. The country’s National Policy on Disaster Prevention and Management (NPDPM) was prepared in 1993. Ethiopia has also ratified the United Nations Framework Convention on Climate Change (UNFCCC) and under the mechanism, a National Adaptation Program of Action (NAPA) was produced in 2001 with an ambition to identify ‘immediate and urgent’ adaptation activities that address current and anticipated adverse effects of climate change and extreme climate events. The Environmental policy of Ethiopia indicates that environmental sustainability to be recognized in policies and strategies as a key prerequisite. In line with this the Environmental Protection Agency (EPA), was established and mainly assumes a regulatory role and coordinates various activities and included policy on climate change and pollution, particularly on promoting climate monitoring programs as the country is sensitive to changes in climate, identifying a firm and demonstrable commitment to the principle of containing climate change and fostering to use hydro, geothermal and solar energy to minimize an emission of greenhouse gases.
Dereje Damte,Md. Ahsanur Reza,Seung-Jin Lee,Woo-Sik Jo,Seung-Chun Park 한국독성학회 2011 Toxicological Research Vol.27 No.1
The present study investigated the anti-inflammatory effects of dichloromethane extract of Auricularia auricula-judae. Dichloromethane extract of Auricularia auricula-judae inhibited Lipopolysaccharide (LPS)-induced nitric oxide (NO) production significantly in a dose-dependent manner in the concentration ≥ 10 μg/ml (p < 0.05). Furthermore, RT-PCR results of this study indicated that the extract markedly reduced the expressions of inflammatory cytokines (IL-6, TNF-α and IL-1β) mRNA in LPS-treated murine RAW 264.7 macrophages, which could possibly ameliorate the inflammation. Nevertheless, dichloromethane extract of Auricularia auricula-judae did not show complete inhibition of IL-6 mRNA expression. The inhibition of IL-1β cytokine at protein level was also observed in a dose dependent manner. In conclusion, the current study revealed the previously unknown effect of dichloromethane ethyl extract of Auricularia auricula-judae inhibitions of the production of NO, IL-6, TNF-α and IL-1β in LPS-stimulated macrophages.
Dereje, Mamo Melaku,Ji, Dongseob,Kang, So-Huei,Yang, Changduk,Noh, Yong-Young Applied Science Publishers 2017 Dyes and pigments Vol.145 No.-
<P><B>Abstract</B></P> <P>In this work, we investigate the effect of pre-aggregated solutions of diketopyrrolopyrrole (DPP)-based conjugated polymers to achieve highly-aligned polymer films for high-performance organic field-effect transistors (OFETs). A suitable marginal solvent is selected for 5-octyl-pentadecyl branched DPP and selenophene-based semiconducting polymer (PDPP(SE)-ε-C<SUB>8</SUB>C<SUB>15</SUB>) by utilizing the Hansen solubility parameter calculation. The anisotropic one-dimensional aligned PDPP(SE)-ε-C<SUB>8</SUB>C<SUB>15</SUB> film was off-center spin-coated from the pre-aggregated solution is studied by atomic force microscopy and polarized UV-Vis absorption spectroscopy. A significantly high hole mobility of 4.16 cm<SUP>2</SUP>V<SUP>−1</SUP>s<SUP>−1</SUP> was achieved from the OFETs with a unidirectionally-aligned PDPP(SE)-ε-C<SUB>8</SUB>C<SUB>15</SUB> film to the transistor channel direction.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Selection of suitable solvent for preparing pre-aggregated solutions of polymers. </LI> <LI> Formation of anisotropic thin films from the pre-aggregated polymer solutions. </LI> <LI> Directionally aligned polymer films differ in property and their FET performances. </LI> <LI> Thin films aligned parallel to the transistor channel direction show high mobility. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Damte, Dereje,Lee, Seung-Jin,Birhanu, Biruk Tesfaye,Suh, Joo-Won,Park, Seung-Chun The Korean Society for Microbiology and Biotechnol 2015 Journal of microbiology and biotechnology Vol.25 No.12
Mycoplasma hyopneumoniae is known to cause porcine enzootic pneumonia (EP), an important disease in swine production. The objective of this study was to examine the effects of sonicated protein fractions of M. hyopneumoniae on inflammatory response and gene expression in the murine alveolar macrophage MH-S cell line. The effects of sonicated protein fractions and intact M. hyopneumoniae on the gene expression of cytokines and iNOS were assessed using RT-PCR. The Annealing Control Primer (ACP)-based PCR method was used to screen differentially expressed genes. Increased transcription of interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, COX-2, and iNOS mRNA was observed after exposure to the supernatant (SPT), precipitant (PPT), and intact M. hyopneumoniae protein. A time-dependent analysis of the mRNA expression revealed an upregulation after 4 h for IL-6 and iNOS and after 12 h for IL-1β and TNF-α, for both SPT and PPT; the fold change in COX-2 expression was less. A dose- and time-dependent correlation was observed in nitrite (NO) production for both protein fractions; however, there was no significant difference between the effects of the two protein fractions. In a differential gene analysis, PCR revealed differential expression for nine gene bands after 3 h of stimulation — only one gene was downregulated, while the remaining eight were upregulated. The results of this study provide insights that help improve our understanding of the mechanisms underlying the pathogenesis of and macrophage defenses against M. hyopneumoniae assault, and suggest targets for future studies on therapeutic interventions for M. hyopneumoniae infections.