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      • SCISCIESCOPUS

        Alternating Copolymer of Sulfonated Poly(ether ether ketone-benzimidazole)s (SPEEK-BI) Bearing Acid and Base Moieties

        Wang, Jianli,Song, Yilin,Zhang, Cheng,Ye, Zhibin,Liu, Hui,Lee, Myong-Hoon,Wang, Dehai,Ji, Jianbing WILEY-VCH Verlag 2008 Macromolecular Chemistry and Physics Vol.209 No.14

        <P>A novel alternating copolymer of sulfonated poly(ether ether ketone-benzimidazole)s (SPEEK-BI) was synthesized by polycondensation of aromatic bisphenol containing benzimidazole and a mixture of sulfonated and non-sulfonated difluorobenzophenones. By varying the amount of two difluorobenzophenones, the ratio of sulfonic acid unit to imidazole base was controlled straightforwardly. The polymer structure was characterized by <SUP>1</SUP>H NMR and IR spectroscopy. Two different methods of ion exchange capacity measurement supported a strong inter- and intra-molecular interaction between acid and base units, which resulted in an improved mechanical strength as well as avoiding phase separation. Tough membranes with good mechanical stability in hot water (80 °C) and alcohol were obtained by solution casting, which is potential for applications in polymer electrolyte membrane fuel cells and membranes for separation of liquids or gases.</P><P> <img src='wiley_img/10221352-2008-209-14-MACP200700610-gra001.gif' alt='wiley_img/10221352-2008-209-14-MACP200700610-gra001'> </P>

      • KCI등재

        A New Cytotoxic Phenazine Derivative from a Deep Sea Bacterium Bacillus sp.

        Dehai Li,Fengping Wang,Xiang Xiao,Xiang Zeng,Qian-Qun Gu,Weiming Zhu 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.5

        A novel phenazine derivative (1) together with six known compounds (2-7) were isolated by bioassay-guided fractionation from the culture broth of a bacterium, Bacillus sp., collected from a Pacific deep sea sediment sample (depth 5059 m). The structures of these compounds were determined using spectroscopic methods. Their cytotoxic effects on P388 and K562 cell lines were preliminarily examined using the sulforhodamine-B (SRB) assay.

      • KCI등재

        The Optimization Algorithm for the Pathfinder Sea Surface Temperature in the East China Seas

        Dehai Song,Xianwen Bao,Xiao Hua Wang,Wen Wu 한국해양과학기술원 2009 Ocean science journal Vol.44 No.1

        Based on the analysis of the quality level in a Pathfinder 4km daily nighttime Sea Surface Temperature product (PFSST) in the East China Seas (ECS) from 1985 to 2004, the proportion of high-quality data was lower than that in the global level. Additionally, the PFSST maps showed clearly the void and anomaly data impacted by atmospheric contamination. In order to solve the above problem, an optimal algorithm was established through introducing the structure function, setting up the daily first-guess sea surface temperature (SST) field and taking PFSST product of the highest quality as reference points. Comparisons were done between this optimally interpolated SST and the selected original PFSST and the simultaneous in situ measurements. It illustrated it was possible to exactly estimate the SST values in the ECS during the recent two decades. The mean bias error and the root mean square error between data sets optimally evaluated and in situ observed were lower than those between the previous global estimations and in situ measurnments. Based on the analysis of the quality level in a Pathfinder 4km daily nighttime Sea Surface Temperature product (PFSST) in the East China Seas (ECS) from 1985 to 2004, the proportion of high-quality data was lower than that in the global level. Additionally, the PFSST maps showed clearly the void and anomaly data impacted by atmospheric contamination. In order to solve the above problem, an optimal algorithm was established through introducing the structure function, setting up the daily first-guess sea surface temperature (SST) field and taking PFSST product of the highest quality as reference points. Comparisons were done between this optimally interpolated SST and the selected original PFSST and the simultaneous in situ measurements. It illustrated it was possible to exactly estimate the SST values in the ECS during the recent two decades. The mean bias error and the root mean square error between data sets optimally evaluated and in situ observed were lower than those between the previous global estimations and in situ measurnments.

      • KCI등재

        The Optimization Algorithm for the Pathfinder Sea Surface Temperature in the East China Seas

        Song, Dehai,Bao, Xianwen,Wang, Xiao Hua,Wu, Wen 한국해양학회 2009 Ocean science journal Vol.44 No.1

        Based on the analysis of the quality level in a Pathfinder 4km daily nighttime Sea Surface Temperature product (PFSST) in the East China Seas (ECS) from 1985 to 2004, the proportion of high-quality data was lower than that in the global level. Additionally, the PFSST maps showed clearly the void and anomaly data impacted by atmospheric contamination. In order to solve the above problem, an optimal algorithm was established through introducing the structure function, setting up the daily first-guess sea surface temperature (SST) field and taking PFSST product of the highest quality as reference points. Comparisons were done between this optimally interpolated SST and the selected original PFSST and the simultaneous in situ measurements. It illustrated it was possible to exactly estimate the SST values in the ECS during the recent two decades. The mean bias error and the root mean square error between data sets optimally evaluated and in situ observed were lower than those between the previous global estimations and in situ measurnments.

      • KCI등재

        Formulation of a rational dosage regimen of ceftiofur hydrochloride oily suspension by pharmacokinetic-pharmacodynamic (PK-PD) model for treatment of swine Streptococcus suis infection

        Wanhe Luo,Dehai Wang,Hua Qin,Dongmei Chen,Yuanhu Pan,Wei Qu,Lingli Huang,Shuyu Xie 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.6

        Background: Our previously prepared ceftiofur (CEF) hydrochloride oily suspension shows potential wide applications for controlling swine Streptococcus suis infections, while the irrational dose has not been formulated. Objectives: The rational dose regimens of CEF oily suspension against S. suis were systematically studied using a pharmacokinetic-pharmacodynamic model method. Methods: The healthy and infected pigs were intramuscularly administered CEF hydrochloride oily suspension at a single dose of 5 mg/kg, and then the plasma and pulmonary epithelial lining fluid (PELF) were collected at different times. The minimum inhibitory concentration (MIC), minimal bactericidal concentration, mutant prevention concentration (MPC), post-antibiotic effect (PAE), and time-killing curves were determined. Subsequently, the area under the curve by the MIC (AUC0–24h/MIC) values of desfuroylceftiofur (DFC) in the PELF was obtained by integrating in vivo pharmacokinetic data of the infected pigs and ex vivo pharmacodynamic data using the sigmoid Emax (Hill) equation. The dose was calculated based on the AUC0–24h/MIC values for bacteriostatic action, bactericidal action, and bacterial elimination. Results: The peak concentration, the area under the concentration-time curve, and the time to peak for PELF's DFC were 24.76 ± 0.92 μg/mL, 811.99 ± 54.70 μg·h/mL, and 8.00 h in healthy pigs, and 33.04 ± 0.99 μg/mL, 735.85 ± 26.20 μg·h/mL, and 8.00 h in infected pigs, respectively. The MIC of PELF's DFC against S. suis strain was 0.25 μg/mL. There was strong concentration-dependent activity as determined by MPC, PAE, and the time-killing curves. The AUC0–24h/MIC values of PELF's DFC for bacteriostatic activity, bactericidal activity, and virtual eradication of bacteria were 6.54 h, 9.69 h, and 11.49 h, respectively. Thus, a dosage regimen of 1.94 mg/kg every 72 h could be sufficient to reach bactericidal activity. Conclusions: A rational dosage regimen was recommended, and it could assist in increasing the treatment effectiveness of CEF hydrochloride oily suspension against S. Suis infections.

      • SCIESCOPUSKCI등재

        A New Cytotoxic Phenazine Derivative from a Deep Sea Bacterium Bacillus sp

        Zhu, Weiming,Li, Dehai,Wang, Fengping,Xiao, Xiang,Zeng, Xiang,Gu, Qian-Qun 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.5

        A novel phenazine derivative (1) together with six known compounds (2-7) were isolated by bioassay-guided fractionation from the culture broth of a bacterium, Bacillus sp., collected from a Pacific deep sea sediment sample (depth 5059 m). The structures of these compounds were determined using spectroscopic methods. Their cytotoxic effects on P388 and K562 cell lines were preliminarily examined using the sulforhodamine-B (SRB) assay.

      • KCI등재

        Fabrication of Transparent Cellulose Fiber Paper by Sequential Treatment of Cationic Cellulose Nanofibers and Polyvinylpyrrolidone

        Furong Xin,Huili Wang,Feixiang Guan,Guodong Li,Zhaoping Song,Dehai Yu,Wenxia Liu 한국섬유공학회 2020 Fibers and polymers Vol.21 No.9

        Paper-based material is receiving more and more attention as an alternative of plastics in flexible electronics. However, conventional paper made of cellulose fibers is opaque owing to its micron-sized void space among fibers. Herein,cellulose fiber paper was changed into transparent paper by sequentially coating cationic cellulose nanofibers (CNFs) andpolyvinylpyrrolidone (PVP). The morphology, transparency, thermal and mechanical properties were analyzed. The resultsshow that the coating of CNFs reduces the micron-sized void space in the cellulose fiber paper, favoring the furtherimprovement on the transparency of paper by coating PVP. By optimizing the coating amount of CNFs and PVP, atransparent paper with a transmittance of 88.5 % at 550 nm is obtained. The as-prepared transparent paper also showsimproved thermal stability, slightly increased tensile strength and significantly enhanced deformation resistance. It was apotential candidate of flexible electronic substrates.

      • KCI등재

        Expediting the Formation of Cellulose Nanopaper by Heterocoagulation of Oppositely Charged Cellulose Nanofibers

        Meng Kang,Chenglong Li,Dehai Yu,Guodong Li,Zhaoping Song,Huili Wang,Wenxia Liu 한국섬유공학회 2022 Fibers and polymers Vol.23 No.7

        Cellulose nanopaper has attracted tremendous attention as an alternative to fossil-based flexible substrates. However, the fabrication of nanopaper from cellulose nanofibers (CNFs) is a time-consuming process. Herein, positivelycharged CNFs (PCNFs) were employed to heterocoagulate negatively charged CNFs (NCNFs) at various PCNF-to-NCNFratios in order to decrease the formation time of nanopaper. At a PCNF-to-NCNF ratio of 1:1, the formation time was reducedfrom 98 min to 20 min. Although heterocoagulation increases the roughness of cellulose nanopaper, nanopapers made from amixture of NCNFs and PCNFs still possess a nanosized network structure and therefore show similar transparency tonanopapers made of pure NCNFs. Compared to the nanopaper made from pure NCNFs, the nanopaper made from themixture of NCNFs and PCNFs showed reduced tensile strength but improved resistance to deformation. This study providesa practical method for the production of cellulose nanopaper.

      • KCI등재

        Correlation of H_2S and COS in the hot coal gas stream and its importance for high temperature desulfurization

        Jianglong Yu,Liping Chang,Wei Xie,Dehai Wang 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.4

        Thermodynamic analysis of the correlation of H_2S and COS has been carried out at the temperature range of 400-650 ℃ at which high temperature desulfurization of coal gas is usually performed. The correlation of the two sulfur species is mainly through the reaction H_2S+CO→COS+H_2. Simulated coal gas with the following composition CO 32.69%, H_2 39.58%, CO_2 18.27%, N2 8.92% and H_2S 0.47% was used in this study, and the equilibrium concentrations of the two species at different temperatures were calculated. The results of Fe-based sorbents during sulfidation were compared with calculations. It is concluded that the above reaction may reach equilibrium concentration in the presence of the Fe-based sorbents, which means the Fe-based sorbents may effectively catalyze the reaction between H_2S and CO. Because of the correlation of the two sulfur species, both can be effectively removed at high temperatures simultaneously, offering high temperature desulfurization some advantages over low temperature desulfurization processes.

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