강원,경북지역 낙엽송 지위지수 적합성 평가에 관한 연구

이대성 ( Dae Sung Lee ),이의섭 ( Eui Sub Lee ),최종현 ( Jong Hyun Choi ),서영완 ( Yeong Wan Seo ),최정기 ( Jung Kee Choi1 ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

본 연구는 강원 및 경북지역의 낙엽송 지위지수의 적합도를 평가하기 위해 실시되었다. 연구자료는 강원 및 경북지역의 45개 낙엽송 인공림 표준지 조사로부터 우세목 1본을 선발하여 수간석 해를 통해 분석되었다. 산림청에서 개발된 지위지수표에 의거하여 본 연구대상지의 지위지수를 산정한 결과, 지위지수가 18 이하로 낮은 지역은 8곳(18%)이었으며, 지위지수가 20 이상으로 우수한 지역이 37곳(82%)으로서 대부분 지역에서 지위지수가 우세하였다. 지위지수곡선의 적합도를 평가하기위해 수간석해목의 과거에서 현재까지의 수고생장에 따른 지위지수의 변화를 도시한 결과, 초기 임령 때 지위지수와 차이가 없는 곳은 단지 8지역(18%)이었으며, 지위지수가 2∼4 m 차이가 발생한 지역이 19곳(42%), 6 m 이상 발생한 지역이 18곳(40%)으로 나타났다. This study was performed to evaluate the compatibility of site index for Larix kaempferi in Gangwon and Kyeongbuk regions. The data were collected and analyzed from stem alalysis of one dominant tree at each of 45 permanent plots installed in the regions. The result of site index estimation following the site index table developed by Korean Forest Service (KFS) showed that 8 plots (18%) were less than site index 18 and 37 plot (82%) greater than site index 20. Height growth changes of stemmed trees until present were illustrated in a graphic form to evaluate the compatibility of site index curve. The result showed that only 8 plots (18%) did not show any change of site index as trees age, 19 plots (42%) fluctuated in 2∼4m and 18 plots (40%) over 6m.

단상 유도형 동기 전동기(LSPM)의 특성해석에 관한 연구

정대성,김승주,이진헌,최재학,이주,Jung, Dae-Sung,Kim, Seung-Ju,Lee, Jin-Hun,Choi, Jae-Hak,Lee, Ju 한국조명전기설비학회 2007 조명·전기설비학회논문지 Vol.21 No.3

가전분야에서의 전동기 효율향상을 통한 에너지 소비절감 효과는 상당히 크지만 이를 위한 전동기의 설계/해석 기술 확보가 아직은 미흡한 상태이다. 이에 따라 유도형 동기전동기가 제안되었지만, 유도형 동기 전동기는 유도전동기와 통기전동기의 특성을 동시에 가지고 있어, 해석 및 설계가 쉽지 않다. 따라서 본 논문에서는 기존의 냉장고 압축기용 전동기인 단상유도전동기를 대처할 수 있는 단상 유도형 동기전동기를 이용해 파라미터에 따라 특성이 어떻게 바뀌는가에 대해 서술하였다. 그에 따라 단상유도전동기의 정상상태 특성을 해석하고 제안모델의 성능을 기존모델과 비교하고 실험하여 해석결과의 신뢰성을 검증한다. 또한 본 논문에서는 제안모델의 기존 고정자 형상이나 권선 스팩을 유지하고 회전자의 형상이나 구조만을 변경시켜 성능향상을 도모하였다. 해석방법으로는 전자장 수치 해석적인 방법으로 널리 이용되고 있는 유한요소법(Finite Element Method : FEM)을 이용하였다. Electric motor efficient improvement from home appliance field is important to the effect reducing the energy consumption. But the electric motor design/analysis technology is still insufficient. Specially the electric motor design/analysis technology of satisfying characteristic of both the induction motor and the synchronous motor such as Line start permanent motor. Therefore the electric motor design/analysis technology is urgently demanded reliability. This paper proposes the sing1e-phase line-start permanent magnet motor to develop the motor it with be able to alternate the sing-phase induction motor it is a refrigerator compressor motor. The sing-phase induction motor is analyzed in the steady state. And we have a certification test to compare our single-phase line-start permanent magnet motor with the sing-phase induction motor. In order to improve the performance, the stator of the single-phase line-start permanent magnet motor is same as the stator of the sing-phase induction motor and changes the rotor form and has the permanent magnet. It used the Finite Element Method(FEM) which is widely used with electronic-magnetic field numerical analysis method.

An evaluation equation of load capacities for CFT square column-to-beam connections with combined diaphragm

Sung-Mo Choi,Do-Sub Jung,Dae-Joong Kim,Jin-Ho Kim 국제구조공학회 2007 Steel and Composite Structures, An International J Vol.7 No.4

The objective of this study is to clarify the structural features of members consisting of connection, as a series of the previous study on the CFT column-to-beam tensile connection with combined cross diaphragm. This connection has the merits that the stress is distributed evenly on the beam flange and the diaphragm and the stress concentration is reduced, by improving the stress transfer route and restraining abrupt deformation of diaphragm. The finite element analysis was performed to find out the stress transfer through sleeve which is an important member of the connection with combined cross diaphragm. The length and thickness of sleeve were used as variables for the analysis. As the analysis results, the length and thickness of sleeve didn’t influence on the capacity of the connection and played a role of a medium to transfer the stress from the diaphragm to the filled concrete. It is proposed that the appropriate length of sleeve be the same value as the diameter of sleeve and the appropriate ratio of sleeve diameter to sleeve thickness be 20. Two equations for evaluation of the load-carrying capacity of the connection were also proposed through the modification of the evaluation equation suggested in the previous study.

Resveratrol analogue HS-1793 induces the modulation of tumor-derived T cells

CHOI, YOO JIN,YANG, KWANG MO,KIM, SUNG DAE,YOO, YOUNG HYUN,LEE, SANG WHA,SEO, SU YEONG,SUH, HONGSUK,YEE, SUNG TAE,JEONG, MIN HO,JO, WOL SOON Spandidos Publications 2012 Experimental and therapeutic medicine Vol.3 No.4

<P>Recent advances in the understanding of the mechanisms responsible for tumor progression suggest the possibility to control cancer growth, not only through chemotherapy-induced cancer cell destruction, but also by stimulating anticancer immunity. However, immune tolerance against tumor antigens disturbs diverse forms of immunotherapy. One of the most potent and well-studied tumor-induced immunosuppressive phenotypes found in the tumor microenvironment is the regulatory subpopulation cells (CD4(+)CD25(+)FoxP3(+)Treg cells). Among the great number of natural agents derived from plants and potentially useful for application in the complementary therapy of cancer, resveratrol is gaining attention for its immunomodulating properties in breast cancer, since the ineffectiveness of numerous immunotherapy strategies may be related, in part, to their negative effects on Treg cells. The present study was undertaken to examine whether HS-1793, a synthetic resveratrol analogue free from the restriction of the metabolic instability and high dose requirement of resveratrol, shows a direct effect on immune responses by enhancing lymphocyte proliferation or an immunomodulatory effect by inducing changes in the Treg cell population in FM3A breast tumor-bearing mice. Although HS-1793 had no direct immunostimulatory effect, it dose-dependently decreased IL-2 secretion and increased IL-4 secretion of concanavalin A-stimulated lymphocytes from tumor-bearing mice, which suggest that HS-1793 may induce changes in the subpopulations of tumor-derived T lymphocytes. The CD4(+)CD25(+) cell population from tumor-bearing mice decreased after HS-1793 treatment in a dose-dependent manner, while the CD4(+) T cell population remained unchanged. FoxP3(+)-expressing cells among the CD4(+)CD25(+) population showed a similar pattern. In contrast, the CD8(+) T cell population as well as the interferon (IFN)-gamma-expressing CD8(+) T cell population and IFN-gamma secretion of splenocytes from tumor-bearing mice were significantly upregulated by HS-1793 treatment. These results suggest that HS-1793 induces the modulation of tumor-derived T lymphocytes, particulary having a suppressive effect on the Treg cell population, likely contributing to enhanced tumor-specific cytotoxic T lymphocyte responses and CD4(+) T cells involving antitumor immunity. Therefore, HS-1793 may serve as a promising adjuvant therapeutic reagent in breast cancer immunotherapy.</P>

Fabrication and Evaluation of Flowmeter with Focused-Ion-Beam System

Choi, Dae Keun,Lee, Sang Hoon Trans Tech Publications, Ltd. 2013 Applied mechanics and materials Vol.389 No.-

<P>In this paper, we fabricated and evaluated the piezoresistive type flowmeter with focused-ion-beam (FIB) system. The flowmeter body is made up of the low stress silicon nitride, and the nanometer sized piezoresistive layer is deposited with FIB system for the smaller measuring area. The flowmeter is evaluated in the wind tunnel, and the 0~4m/s air flows are applied. Although the sensitivity, ΔR/R shows the negative behavior unlike the conventional piezoresistive layer due to the added materials during the FIB process, the measurement results show the ΔR/R has a suitable sensitivity (-1.04E-2/ms-1) and a rapid response time (0.8sec). Those results represent the fabricated piezoresistive type air flowmeter has the possibility for the small area detection.</P>

Risk factors for conversion to conventional laparoscopic cholecystectomy in single incision laparoscopic cholecystectomy

Sung Gon Kim,Ju Ik Moon,In Seok Choi,Sang Eok Lee,Nak Song Sung,Ki Won Chun,Hye Yoon Lee,Dae Sung Yoon,Won Jun Choi 대한외과학회 2016 Annals of Surgical Treatment and Research(ASRT) Vol.90 No.6

Purpose: The aim of this study was to investigate the risk factors for conversion to conventional laparoscopic cholecystectomy (CLC) in single incision laparoscopic cholecystectomy (SILC) along with the proposal for procedure selection guidelines in treating patients with benign gallbladder (GB) diseases. Methods: SILC was performed in 697 cases between April 2010 and July 2014. Seventeen cases (2.4%) underwent conversion to conventional LC. We compared these 2 groups and analyzed the risk factors for conversion to CLC. Results: In univariate analysis, American Society of Anesthesiologist score > 3, preoperative percutaneous transhepatic GB drainage status and pathology (acute cholecystitis or GB empyema) were significant risk factors for conversion (P = 0.010, P = 0.019 and P < 0.001). In multivariate analysis, pathology (acute cholecystitis or GB empyema) was significant risk factors for conversion to CLC in SILC (P < 0.001). Conclusion: Although SILC is a feasible method for most patients with benign GB disease, CLC has to be considered in patients with acute cholecystitis or GB empyema because it is likely to result in inadequate visualization of the Calot’s triangle and greater bleeding risk.

ORiginal Article : Effects of DA-9701, a Novel Prokinetic Agent, on Phosphorylated Extracellular Signal-Regulated Kinase Expression in the Dorsal Root Ganglion and Spinal Cord Induced by Colorectal Distension in Rats

( Sang Pyo Lee ),( Kang Nyeong Lee ),( Oh Young Lee ),( Hang Lak Lee ),( Dae Won Jun† ),( Byung Chul Yoon ),( Ho Soon Choi ),( Se Jin Hwang ),( Seo Eun Lee ) The Editorial Office of Gut and Liver 2014 Gut and Liver Vol.8 No.2

Background/Aims: DA-9701, a standardized extract of Pharbitis Semen and Corydalis Tuber, is a new prokinetic agent that exhibits an analgesic effect on the abdomen. We investigated whether DA-9701 affects visceral pain induced by colorectal distension (CRD) in rats. Methods: A total of 21 rats were divided into three groups: group A (no CRD+no drug), group B (CRD+no drug), and group C (CRD+DA-9701). Expression of pain-related factors, substance P (SP), c-fos, and phosphorylated extracellular signal-regulated kinase (p-ERK) in the dorsal root ganglion (DRG) and spinal cord was determined by immunohistochemical staining and Western blotting. Results: The proportions of neurons in the DRG and spinal cord expressing SP, c-fos, and p-ERK were higher in group B than in group A. In the group C, the proportion of neurons in the DRG and spinal cord expressing p-ERK was lower than that in group B. Western blot results for p-ERK in the spinal cord indicated a higher level of expression in group B than in group A and a lower level of expression in group C than in group B. Conclusions: DA-9701 may decrease vis-ceral pain via the downregulation of p-ERK in the DRG and spinal cord. (Gut Liver 2014;8:140-147)

Dipeptidyl Peptidase-4 Induces Aortic Valve Calcification by Inhibiting Insulin-Like Growth Factor-1 Signaling in Valvular Interstitial Cells

Choi, Bongkun,Lee, Sahmin,Kim, Sang-Min,Lee, Eun-Jin,Lee, Sun Ro,Kim, Dae-Hee,Jang, Jeong Yoon,Kang, Sang-Wook,Lee, Ki-Up,Chang, Eun-Ju,Song, Jae-Kwan American Heart Association 2017 Circulation Vol.135 No.20

<P>CONCLUSIONS: DPP-4-dependent insulin-like growth factor-1 inhibition in VICs contributes to aortic valve calcification, suggesting that DPP-4 could serve as a potential therapeutic target to inhibit calcific aortic valve disease progression.</P>

Evaluation of Properties of FIB Deposited Metal Layer and Application to Temperature Sensing

Choi, Dae Keun,Lee, Sang Hoon Trans Tech Publications, Ltd. 2013 Applied mechanics and materials Vol.319 No.-

<P>In this paper, the properties of Focused-Ion-Beam (FIB) deposited platinum layer are investigated using the MEMS processes. First, the electrical properties are examined with three parallel metal lines and the measurement result shows over one hundred times larger resistivity than that of the conventional platinum layer. This feature is due to the additional materials like carbon compound and the gallium ion. The thermal properties are also investigated about the temperature coefficient of resistivity (TCR). The measured TCR values are -0.0015~-0.0020 K-1 which are different from the positive TCR in conventional platinum layer. The carbon compound has negative TCR and changes the properties of FIB metal layer. Although some non-uniform properties are observed, the properties of FIB deposited platinum layer are sufficient for the temperature sensing applications at small area.</P>

Methanol extract of Sanguisorba officinalis L. with cytotoxic activity against PC3 human prostate cancer cells

CHOI, EUN-SUN,KIM, JUN-SUNG,KWON, KI-HAN,KIM, HYNG-SEOP,CHO, NAM-PYO,CHO, SUNG-DAE Spandidos Publications 2012 MOLECULAR MEDICINE REPORTS Vol.6 No.3

<P>Sanguisorba officinalis is a natural plant that has been traditionally used for the treatment of inflammatory and metabolic diseases. Several studies have reported that its extracts exhibit anticancer, antioxidative and anti-lipid peroxidation activities. However, the effects of this plant on human prostate cancer cells have not yet been investigated. In the present study, we investigated the inhibitory effects and underlying mechanisms of a methanol extract of Sanguisorba officinalis (MESO) in PC3 human prostate cancer cells. MESO significantly decreased cell growth and induced apoptosis through the intrinsic apoptosis pathway. MESO decreased the expression levels of myeloid cell leukemia-1 (Mcl-1), a Bcl?2?like anti-apoptotic protein that is highly expressed in various cancer cell lines. Expression levels of the pro-apoptotic protein Bax were increased by MESO whereas those of Bak and Bcl-xL were unchanged. In addition, MESO induced the oligomerization of Bax in the mitochondrial outer membrane. These results suggest that MESO inhibits the growth of prostate cancer cells and induces apoptotic cell death by the downregulation of Mcl-1 protein expression and the oligomerization of Bax. Therefore, MESO has potential as a drug candidate for the treatment of prostate cancer.</P>