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Modular Intermeshing Co-rotating Twin Screw Extruder 내에서 제조된 PC/ABS 블랜드의 물리적, 유변학적 성질
방대석,정우형 금오공과대학교 2006 論文集 Vol.27 No.-
The physical properties and melt behavior of PC/ABS blends may be significantly affected by mixing equipments and processing conditions. In this study, the physical and rheological properties of PC/ABS blends in a modular interrneshing co-rotating twin screw extruder were investigated. PC and ABS were blended by different conditions such as different compositions of PC and ABS, and the several types of screw configurations in a modular interrneshing co-rotating twin screw extruder. After extrusion, the specimens were fabricated by injection molding. Then the physical properties were measured by tensile and Izod-irrpact tests. The melt behavior was observed with the capillary rheometer. Mixing and melting behaviors in the extruder were investigated by the cooling experiment for the different screw configurations.
치합형 역방향회전(Intermeshing Counter-Rotating) 이축스크류식 압출기내의 등온 비뉴토니언 흐름 분석
방대석,홍명혁,정영진 國立金烏工科大學校 産業技術開發硏究院 2002 産業技術開發硏究 Vol.18 No.-
A proper and correct formulation of an isothermal non-Newtonian flow in intermeshing counter-rotating twin screw extruder modules which accounts clearly for the positive pumping displacement mechanism is presented. Screw pumping characteristic curves were determined for various typical elements of the Leistritz modular intermeshing counter-rotating twin screw extruder.
박일현,이종근,윤관한,조동환,민병길,방대석 金烏工科大學校 2000 論文集 Vol.21 No.-
The Rayleigh ratio of benzene is a very important physical constant with which the integrated scattered intensity of laser light scattering can be converted into the absolute value. In this study temperature dependence of Rayleigh ratio of this solvent has been investigated with two different methods in the temperature range of 25-75℃. It was found that in the direct measurement the non-linear behavior of its Rayleigh ratio were observed as increasing temperature even if the scattering volume correction was applied to the scattered intensity of benzene. However the result of indirect measurement based upon the invariance of molecular weight of standard polystyrene polymer for any polymer solution temperature showed us that its temperature dependence up to 75℃ could be expressed with the Benoit's linear equation rather than the non-linear one. It seems that the scattered intensity in direct method has more complicate contributions at the elevated temperature. Further research works are necessary in order to solve such discrepancy clearly.
Dae Yun Seo,Hyo Bum Kwak,Sung Ryul Lee,Yeun Suk Cho,In-Sung Song,Nari Kim,Hyun Seok Bang,Byoung Doo Rhee,Kyung Soo Ko,Byung Joo Park,Jin Han 한국영양학회 2014 Nutrition Research and Practice Vol.8 No.2
BACKGROUND/OBJECTIVES: Irisin, a newly identified hormone, is associated with energy homeostasis. We investigated whether aged garlic extract (AGE) and exercise training intervention could improve body weight, insulin sensitivity, skeletal muscle fibronectin domain containing protein 5 (FNDC-5) levels, and plasma irisin in high-fat diet (HFD). MATERIALS/METHODS: Male Sprague Dawley rats were fed a ND (normal diet, n = 5) or HFD (n = 28) for 6 weeks. After 6 weeks, all rats were divided into 5 groups for the next 4 weeks: ND, (normal diet, n = 5), HFD (high-fat diet, n = 7), HFDA (high-fat diet + aged garlic extract, n = 7), HFDE (high-fat diet + exercise, n = 7), and HFDEA (high-fat diet + exercise + aged garlic extract, n = 7). Exercise groups performed treadmill exercises for 15-60 min, 5 days/week, and AGE groups received AGE (2.86 g/kg, orally injected) for 4 weeks. RESULTS: Significant decreases in body weight were observed in the ND, HFDE, and HFDEA groups, as compared with the HFD group. Neither intervention affected the masses of the gastrocnemius muscle or liver. There were no significant differences in glucose levels across the groups. The homeostatic model assessments of insulin resistance were significantly higher in the HFD group, as compared with the ND, HFDA, HFDE, and HFDEA groups. However, skeletal muscle FNDC-5 levels and plasma irisin concentrations were unaffected by AGE or exercise in obese rats. AGE supplementation and exercise training did not affect skeletal muscle FNDC-5 or plasma irisin, which are associated with insulin sensitivity in obese rats. CONCLUSION: Our results suggest that the protection against HFD-induced increases in body fat/weight and insulin resistance that are provided by AGE supplementation and exercise training may not be mediated by the regulation of FNDC-5 or irisin.
Dae-Hyuk Heo,Yu Min Kang,송경호,Jun-Won Seo,Jeong-Han Kim,June Young Chun,전강일,강창경,Song Mi Moon,Pyoeng Gyun Choe,Wan Beom Park,Ji Hwan Bang,Eu Suk Kim,Hong Bin Kim,Sang-Won Park,Won Sup Oh,Nam Joong Kim,M 대한의학회 2020 Journal of Korean medical science Vol.35 No.11
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high mortality in East Asia. This study aimed to develop, for primary care providers, a prediction score using initial symptoms and basic laboratory blood tests to differentiate between SFTS and other endemic zoonoses in Korea. Methods: Patients aged ≥ 18 years diagnosed with endemic zoonoses during a 3-year period (between January 2015 and December 2017) were retrospectively enrolled from 4 tertiary university hospitals. A prediction score was built based on multivariate logistic regression analyses. Results: Of 84 patients, 35 with SFTS and 49 with other endemic zoonoses were enrolled. In multivariate logistic regression analysis, independent predictors of SFTS included neurologic symptoms (odds ratio [OR], 12.915; 95% confidence interval [CI], 2.173–76.747), diarrhea (OR, 10.306; 95% CI, 1.588–66.895), leukopenia (< 4,000/mm3 ) (OR, 19.400; 95% CI, 3.290– 114.408), and normal C-reactive protein (< 0.5 mg/dL) (OR, 24.739; 95% CI, 1.812–337.742). We set up a prediction score by assigning one point to each of these four predictors. A score of ≥ 2 had 82.9% sensitivity (95% CI, 71.7%–87.5%) and 95.9% specificity (95% CI, 88.0%–99.2%). The area under the curve of the clinical prediction score was 0.950 (95% CI, 0.903–0.997). Conclusion: This study finding suggests a simple and useful scoring system to predict SFTS in patients with endemic zoonoses. We expect this strategic approach to facilitate early differentiation of SFTS from other endemic zoonoses, especially by primary care providers, and to improve the clinical outcomes.
Bang, In-Soo,Park, Hee-Yong,Yuh, Chung-Suk,Kim, Ae-Jung,Yu, Chang-Yeon,Ghimire, Bimal,Lee, Han-Shin,Park, Jae-Gun,Choung, Myoung-Gun,Lim, Jung-Dae The Korean Society of Medicinal Crop Science 2007 韓國藥用作物學會誌 Vol.15 No.2
The objective of this research was to evaluate the ability of water and ethanol extracts from mulberry fruit (Morus alba L.) to influence the inhibitory activity of angiotensin converting enzyme (ACE) and xanthine oxidase(XOase). The total phenol contents and sixteen phenolic compounds were investigated in water and ethanol extracts. In order to understand the factors responsible for the potent antioxidant and antihypertensive ability of mulberry, it has been evaluated for anti-oxidative activity using Fenton's reagent/ethyl linoleate system and for free radical scavenging activity using the 1,1-diphenyl-2-picryl hydrazyl free radical generating system. The total phenol contents and total of phenolic compounds in ethanol extract showed higher levels than water extract in mulberry fruit six phenolic compounds (chlorogenic acid, narigin, syringic acid, quercetin, naringenin, kampferol) has a higher individual phenolic compound content in the 60% ethanol extraction than 80% ethanol extract. The inhibitory activity on angiotensin converting enzyme (ACE) were highest in 80% ethanol extract (9.0%). Also, activity of xanthine oxidase(XOase) inhibition appeared highest in 80% ethanol extracts and correlated well with the total phenolic content, which was modulated by the concentration of individual phenolic compounds. This result revealed, that strong biological activity was caused by specific phenol compound contents. Utilization of water and ethanol extracts from mulberry fruit are expected to be good candidate for development into source of free radical scavengers and anti-hypertentive activity
( Dae Sung Lee ),( Ki Bae Bang ),( Ji Yeon Kim ),( Yoon Suk Jung ),( Jung Ho Park ),( Hong Joo Kim ),( Yong Kyun Cho ) 대한장연구학회 2016 Intestinal Research Vol.14 No.1
Quality of life is closely related to anemia in patients with inflammatory bowel disease (IBD). Several studies have reported on anemia in patients with IBD in Western countries. This study investigated the prevalence and clinical characteristics of anemia in Korean patients with IBD. Methods: We reviewed the medical records of 92 patients with ulcerative colitis (UC) and 76 patients with Crohn’s disease (CD) who were followed regularly at a single tertiary medical center in Korea between January 2003 and December 2012. Hemoglobin (Hb) thresholds used to define anemia were <13.0 g/dL in men and <12.0 g/dL in women according to the World Health Organization criteria. We chose the lowest Hb level in each year as a representative value because Hb levels changed at each examination and anemia was associated with disease deterioration. The relationship between clinical variables and lowest Hb level was assessed. Results: The prevalence of anemia was 36.3% in patients with UC and 41.6% in patients with CD. Anemia in patients with CD was associated with hospital admission, 5-aminosalicylate (5-ASA) and infliximab treatment in men. Anemia in patients with UC was associated with hospital admission, oral steroid use, thiopurine and infliximab treatment in men. Conclusions: The prevalence of anemia in Korean patients with IBD was comparable to that of patients in Western countries. Anemia was associated with male patients with CD who were admitted to the hospital and received medications including 5-ASA and infliximab, and men with UC who were admitted to the hospital and received medications including oral steroids, thiopurine and infliximab. (Intest Res 2016;14:43-49)
( Dae Sung Lee ),( Ki Bae Bang ),( Ji Yeon Kim ),( Yoon Suk Jung ),( Jung Ho Park ),( Hong Joo Kim ),( Dong Il Park ),( Yong Kyun Cho ),( Jung Il Sohn ),( Woo Kyu Jeon ),( Byung Ik Kim ),( Kyu Yongcho 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Quality of life is closely related to anemia in patients with inflammatory bowel disease (IBD). Several studies have examined prevalence, cause, outcomes, and therapy related to the anemia of IBD in Western country. The aim of this study was to investigate the prevalence and clinical characteristics of anemia in Korean patients with IBD. Methods: We reviewed the medical records of 92 patients with ulcerative colitis (UC) and 82 patients with Crohn`s disease (CD) who were followed regularly at a single tertiary medical center in Korea between January 2003 and December 2012. Hemoglobin thresholds used to define anemia were Results: The prevalence of anemia was 36.3% in UC (41.4% in women and 33.1% in men) and 41.6% in CD (56.6% in women and 39.4% in men). Anemia in CD was associated with admission (p=0.01) and 5-aminosalicylate (5-ASA) (p=0.033) and infliximab (p=0.039) treatment in men. Anemia in UC was associated with admission (p=0.017) and oral steroid (p=0.003), thiopurine (p=0.003), and infliximab (p=0.008) treatment in men. Conclusions: The prevalence of anemia in Korean patients with IBD was comparable to that of the Western. Anemia was associated with admission and 5-ASA and infliximab treatment in men with CD and with admission and oral steroid, thiopurine, and infliximab treatment in men with UC.