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      • KCI등재

        이명박 정부의 대북정책 : 평가와 전망

        문정인,이춘복 연세대학교 통일연구원 2009 통일연구 Vol.13 No.2

        이명박 정부 들어 지난 1년간 남북관계는 경색, 악화 국면을 넘어 거의 단절 수준까지 이르렀다. 특히 서해안에서의 해상 충돌과 그에 따른 군사적 긴장의 고조는 역대 최악의 남북관계를 예고해 주고 있다. 이러한 상황전개는 북측의 일방적 태도와 이명박 정부의 경직된 대북정책이 빚어낸 결과라 할 수 있다. 특히 비핵·개방·3000』과 ABR(Anything But Roh Moo-hyun)이라는 이명박 정부의 대북정책 기조는 남북관계 개선에 커다란 걸림돌이 되고 있다. 대북관계에서 지나치게 지난 정권과의 차별화를 강조함으로 남북관계는 위기로 치닫고 있으며 과거 화해협력정책이 애써 이룩해 놓은 성과마저 점차 무력화되고 있다. 현재의 고착 상태를 극복하기 위해서는 남북간 신뢰 회복이 선행되어야 하며 이를 위해 역지사지의 대북정책이 모색되어야 할 것이다. 중도실용주의 원칙에 기초하여 이명박 대통령이 직접 「6.15선언」과 「10.4선언」의 존중의사를 밝히는 동시에 제 3차 남북정상회담의 개최를 통해 새로운 돌파구를 마련해야 할 것이다. Since the inauguration of the Lee Myung-bak (MB) government, inter-Korean relations have remained stalled. The Mt. Keumgang tourist project was shut down since July 2008, the Kaesung Industrial Complex is being jeopardized. And official contacts between two Koreas are virtually frozen. New hope formed through the resumption of reunion of separated families in October was again derailed by naval clash in West Sea in November. The stalemate can be attributed partly to North Korea's inertia-driven behavior and partly to the MB government's rigid stance on North Korea. The latter's blind obsession with the "De-nuke, Open 3,000" policy and the attitude of 'Anything But Roh Moo-hyun (ABR)' is likely to further strain inter-Korean relations, while heightening military tension. The most viable way to overcome the current dilemma is to engage with North Korea, to honor policy legacies of past governments such as the June 15 Joint Declaration and the October 4 North-South Summit Declaration, and to expedite the 3rd inter-Korean summit. In so doing, the MB government needs to adopt an inter-subjective approach to the understanding of North Korea because it can enhance inter-Korean trust-building, exchanges and cooperation, and eventually peaceful co-existence.

      • KCI등재

        Treatment outcomes of patients with stage II pure endometrioid-type endometrial cancer: a Taiwanese Gynecologic Oncology Group (TGOG-2006) retrospective cohort study

        Hung-Chun Fu,Jen-Ruei Chen,Min-Yu Chen,Keng-Fu Hsu,Wen-Fang Cheng,An Jen Chiang,Yu-Min Ke,Yu-Chieh Chen,Yin-Yi Chang,Chia-Yen Huang,Chieh-Yi Kang,Yuan-Yee Kan,Sheng-Mou Hsiao,Ming-Shyen Yen 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.5

        Objective: Choice of hysterectomy and adjuvant treatment for International Federation of Gynecology and Obstetrics (FIGO) 2009 stage II endometrioid endometrial cancer (EEC) is still controversial. Aims of this study were to evaluate survival benefits and adverse effects of different hysterectomies with or without adjuvant radiotherapy (RT), and to identify prognostic factors. Methods: The patients at 14 member hospitals of the Taiwanese Gynecologic Oncology Group from 1992 to 2013 were retrospectively investigated. Patients were divided into simple hysterectomy (SH) alone, SH with RT, radical hysterectomy (RH) alone, and RH with RT groups. Endpoints were recurrence-free survival (RFS), overall survival (OS), disease-specific survival (DSS), adverse effects and prognostic factors for survival. Results: Total of 246 patients were enrolled. The 5-year RFS, OS, DSS and recurrence rates for the entire cohort were 89.5%, 94.3%, 96.2% and 10.2%, respectively. Patients receiving RH had more adverse effects including blood loss (p<0.001), recurrent urinary tract infections (p=0.013), and leg lymphedema (p=0.038). Age over 50-year (HR=9.2; 95% confidence interval [CI], 1.2–70.9) and grade 3 histology (HR=7.28; 95% CI, 1.45–36.6) were independent predictors of OS. Grade 3 histology was an independent predictor of RFS (HR=5.13; 95% CI, 1.38–19.1) and DSS (HR=5.97; 95% CI, 1.06–58.7). Patients receiving adjuvant RT had lower locoregional recurrence (p=0.046), but no impact on survival. Conclusion: Different treatment modalities yield similar survival outcomes. Patients receiving SH with RT had lower locoregional recurrent with acceptable morbidity. Age and tumor grading remained significant predictors for survival among patients with FIGO 2009 stage II EEC.

      • SCIESCOPUS

        Analytical solutions for skewed thick plates subjected to transverse loading

        Chun, Pang-Jo,Fu, Gongkang,Lim, Yun Mook Techno-Press 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.38 No.5

        This paper presents analytical solutions for skewed thick plates under transverse loading that have previously been unreported in the literature. The thick plate solution is obtained in a framework of an oblique coordinate system. The governing equation is first derived in the oblique coordinate system, and the solution is obtained using deflection and rotation as partial derivatives of a potential function developed in this research. The solution technique is applied to three illustrative application examples, and the results are compared with numerical solutions in the literature and those derived from the commercial finite element analysis package ANSYS 11. These results are in excellent agreement. The present solution may also be used to model skewed structures such as skewed bridges, to facilitate efficient routine design or evaluation analyses, and to form special elements for finite element analysis. At the same time, the analytical solution developed in this research could be used to develop methods to address post-buckling and dynamic problems.

      • SCIESCOPUS

        Partial turbulence simulation and aerodynamic pressures validation for an open-jet testing facility

        Fu, Tuan-Chun,Chowdhury, Arindam Gan,Bitsuamlak, Girma,Baheru, Thomas Techno-Press 2014 Wind and Structures, An International Journal (WAS Vol.19 No.1

        This paper describes partial turbulence simulation and validation of the aerodynamic pressures on building models for an open-jet small-scale 12-Fan Wall of Wind (WOW) facility against their counterparts in a boundary-layer wind tunnel. The wind characteristics pertained to the Atmospheric Boundary Layer (ABL) mean wind speed profile and turbulent fluctuations simulated in the facility. Both in the wind tunnel and the small-scale 12-Fan WOW these wind characteristics were produced by using spires and roughness elements. It is emphasized in the paper that proper spectral density parameterization is required to simulate turbulent fluctuations correctly. Partial turbulence considering only high frequency part of the turbulent fluctuations spectrum was simulated in the small-scale 12-Fan WOW. For the validation of aerodynamic pressures a series of tests were conducted in both wind tunnel and the small-scale 12-fan WOW facilities on low-rise buildings including two gable roof and two hip roof buildings with two different slopes. Testing was performed to investigate the mean and peak pressure coefficients at various locations on the roofs including near the corners, edges, ridge and hip lines. The pressure coefficients comparisons showed that open-jet testing facility flows with partial simulations of ABL spectrum are capable of inducing pressures on low-rise buildings that reasonably agree with their boundary-layer wind tunnel counterparts.

      • KCI등재

        Preparation of polyaminated Fe3O4@chitosan core-shell magnetic nanoparticles for efficient adsorption of phosphate in aqueous solutions

        Chun-Chieh Fu,Hai Nguyen Tran,Xing-Han Chen,Ruey-Shin Juang 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.83 No.-

        In this study, novel polyethylenimine (PEI)-grafted chitosan (CS) core-shell (called as Fe3O4/CS/PEI)magnetic nanoparticles were synthesized and applied for adsorbing phosphate in water. The magneticand physicochemical properties of as-synthesized nanoparticles werefirst analyzed by means of asuperconducting quantum interference device, X-ray diffractometer, X-ray photoelectron spectroscope,Fourier-transform infrared spectroscope, transmission electron microscope, zeta potential analyzer, andnitrogen sorptiometer. The followed experiments indicated that the amount of phosphate adsorbedincreased with increasing equilibrium pH to near 4.0 and then decreased when the pH was furtherincreased. The adsorption isotherms of phosphate on Fe3O4/CS/PEI particles were wellfit by the Langmuirequation, and its maximum adsorption was 48.2 mg g 1 at an equilibrium pH of 3.0 and 25 C. Theprimary mechanism for phosphate adsorption on Fe3O4/CS/PEI particles was electrostatic attraction. Thepreferential adsorption of phosphate in the presence of other excess anions including chloride, nitrate,carbonate, and sulfate was presented. Under the conditions studied, more than 90% of phosphate wasdesorbed from the laden Fe3O4/CS/PEI particles by 0.05 mol L 1 of NaOH solution. The remainedadsorption efficiency obtained in thefive-cycle reusability tests has demonstrated the promisingapplication potential of Fe3O4/CS/PEI particles.

      • Study on Photosynthesis Reaction of Plants at Different Light Wavelengths Mix Ratio under Low Power

        ( Chun-yu Tsai ),( Xin-yi Lin ),( Yung-fu Yen ),( Chyung Ay ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        The environmental factors such as light, carbon dioxide, temperature, and nutrition are very important and closely related to the stable control of plant growth in plant factories. However, how to configure the light source at different light wavelengths to increase the physiological response of chlorophyll is also a knowledge. In this study, Boston Lettuce and Red Lettuce (Ziyan) were used as samples and planted in the NFT (Nutrient Film Technology) cultivation system. The effects of different light wavelengths combination on photosynthesis were analyzed to find the optimal ratio of light sources. In addition, sample analysis was performed on these two plants to verify the correctness of the light wavelengths combination ratio. The preliminary results show that the green leaves Boston lettuce have the highest photosynthetic efficiency under the combination of the red wavelength (38.4 μmol) + blue wavelength (57.6 μmol) + green wavelength (24 μmol), while the red leaves Ziyan lettuce had the best photosynthetic efficiency under red wavelength (43.2 μmol) + blue wavelength (64.8 μmol) + yellow wavelength (12 μmol). At the end of the experiment, plant sample analysis will be performed using these two ratios of light wavelengths, verifying that the leaves of two different lettuces strains have its most suitable ratio of light wavelengths, allowing plants to grow efficiently, improve yield, quality and other advantages.

      • KCI등재

        EFFECTS OF CARBON NANOTUBES ON RAT LIVER AND BRAIN

        FU-DE WANG,CHAN JIN,LING-LING CAO,HAO LIANG,CHUN-WANG MA 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.7

        Carbon nanotubes (CNTs) have been widely applied in various ¯elds due to excellent physicaland chemical properties. As production and applications of nanotubes expand, public concernabout their potential risks to human health has also risen. In the present study, the e®ects ofCNTs on rat liver and brain by single intratracheal instillation were detected. CNTs [eithersingle-walled carbon nanotubes (SWCNTs) or multi-walled carbon nanotubes (MWCNTs)] couldbe seen in the lung and liver indicating the transfer of CNTs by blood stream. CNTs could induceoxidative stress in liver with elevated Malondialdehyde (MDA) level and degressive GSH level,superoxide dismutase (SOD) and CAT activity. To brain, maybe due to the blood brain barrierand the increased SOD and CAT activity, serious oxidative stress of brain did not occur.

      • KCI등재

        Tazarotene-Induced Gene 1 Interacts with DNAJC8 and Regulates Glycolysis in Cervical Cancer Cells

        Chun-Hua Wang,Rong-Yaun Shyu,Chang-Chieh Wu,Mao-Liang Chen,Ming-Cheng Lee,Yi-Yin Lin,Lu-Kai Wang,Shun-Yuan Jiang,Fu-Ming Tsai 한국분자세포생물학회 2018 Molecules and cells Vol.41 No.6

        The tazarotene-induced gene 1 (TIG1) protein is a retinoid-inducible growth regulator and is considered a tumor suppressor. Here, we show that DnaJ heat shock protein family member C8 (DNAJC8) is a TIG1 target that regulates glycolysis. Ectopic DNAJC8 expression induced the translocation of pyruvate kinase M2 (PKM2) into the nucleus, subsequently inducing glucose transporter 1 (GLUT1) expression to promote glucose uptake. Silencing either DNAJC8 or PKM2 alleviated the upregulation of GLUT1 expression and glucose uptake induced by ectopic DNAJC8 expression. TIG1 interacted with DNAJC8 in the cytosol, and this interaction completely blocked DNAJC8-mediated PKM2 translocation and inhibited glucose uptake. Furthermore, increased glycose uptake was observed in cells in which TIG1 was silenced. In conclusion, TIG1 acts as a pivotal repressor of DNAJC8 to enhance glucose uptake by partially regulating PKM2 translocation.

      • SCIESCOPUS

        A proposed technique for determining aerodynamic pressures on residential homes

        Fu, Tuan-Chun,Aly, Aly Mousaad,Chowdhury, Arindam Gan,Bitsuamlak, Girma,Yeo, DongHun,Simiu, Emil Techno-Press 2012 Wind and Structures, An International Journal (WAS Vol.15 No.1

        Wind loads on low-rise buildings in general and residential homes in particular can differ significantly depending upon the laboratory in which they were measured. The differences are due in large part to inadequate simulations of the low-frequency content of atmospheric velocity fluctuations in the laboratory and to the small scale of the models used for the measurements. The imperfect spatial coherence of the low frequency velocity fluctuations results in reductions of the overall wind effects with respect to the case of perfectly coherent flows. For large buildings those reductions are significant. However, for buildings with sufficiently small dimensions (e.g., residential homes) the reductions are relatively small. A technique is proposed for simulating the effect of low-frequency flow fluctuations on such buildings more effectively from the point of view of testing accuracy and repeatability than is currently the case. Experimental results are presented that validate the proposed technique. The technique eliminates a major cause of discrepancies among measurements conducted in different laboratories. In addition, the technique allows the use of considerably larger model scales than are possible in conventional testing. This makes it possible to model architectural details, and improves Reynolds number similarity. The technique is applicable to wind tunnels and large scale open jet facilities, and can help to standardize flow simulations for testing residential homes as well as significantly improving testing accuracy and repeatability. The work reported in this paper is a first step in developing the proposed technique. Additional tests are planned to further refine the technique and test the range of its applicability.

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