A Study of Psychotherapy Plan through Game Graphics Focused on Color Preference of Children

Choung-Hun Lee,Su-Hyun Jin,Won-Hyung Lee 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.7

Colors are recognized by human vision or visual organ. In particular, many studies show that these colors have been proved to give great influences on cognitive development and emotional formation of children. The subconsciousness of children is detectable by colors and through this, their inner emotions and subconsciousness can be revealed. Children have higher interaction of emotion and feelings with colors than adults. Moreover, children tend to express their subconsciousness through colors. However, children are defenselessly exposed to colors coming from the IT devices due to the broad diffusion of these appliances. Different types of media materials give impact on the emotions and cognitive development of children. Likewise, the colors represented by media materials considerably exert influence on the emotions and cognitive development of children. With this in mind, this study proposes design game graphics through analysis of colors, composition, nature and character of these colors preferred by children.

HBV : PE-005 ; Long-term treatment efficacy of entecavir therapy in naive patients with chronic hepatitis B with partial virological response

( Dae Hun Kwon ),( In Hee Kim ),( Bum Su Choung ),( Seong Hun Kim ),( Sang Wook Kim ),( Seung Ok Lee ),( Soo Teik Lee ),( Dae Ghon Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

Background: Partial virological response (PVR) to less potent nucleos(t)ide analogues was associated with risk of antiviral resistance in naive chronic hepatitis B (CHB) patients. However, there were limited data for PVR to more potent drug entecavir (ETV). The objective of this study was to investigate the continuous long-term treatment efficacy of ETV in naive CHB patients with PVR. Methods: This study included 227 naive patients who were treated with ETV 0.5mg for more than 12 months between March 2007 and June 2011. PVR was defined as more than 1 log10 decline of viremia from baseline but a detectable serum HBV DNA by PCR (>20 IU/mL) at week 48. Complete virologic response (CVR) was defined as undetectable serum HBV DNA by PCR (<20 IU/mL) at week 48. Results: At week-48, CVR was 162/227 (71.4%) and PVR was 65/227 (28.6%). HBeAg positivity, baseline serum HBV DNA level (≥8 log10IU/mL), serum HBV DNA at week 12 ≥2,000 IU/mL, serum HBV DNA at week 24 ≥2,000 IU/mL were independently associated with PVR at week 48. Cumulated probabilities of virologic response (<20 IU/mL) at week 96 and 144 in patinets with PVR were 50.9% and 76.2%. In subgroup analysis, patients with PVR and low serum HBV DNA level at week 48 (20-2,0000 IU/mL) showed significantly higher achievement of virologic response at week 96 and 144 than those with PVR and high viral load (≥2,0000 IU/mL) during long-term ETV monotherapy (64.9% vs. 25% and 75.0% vs. 25%, p=0.044). Cumulative probabilities of virological breakthrough at week 96, 144 were 1.6%, 1.6% in patients with CVR and 0%, 5.9% in those with PVR, respectively (p=0.092). However, genotypic resistance was 0% and 5.9% in those with CVR and PVR, respectively (p=0.067) Conclusions: Long-term continuous ETV monotherapy in NA-naive patients with PVR at week 48 could achieve further virologic response without significant antiviral resistance.

HBV : PE-005 ; Long-term treatment efficacy of entecavir therapy in naive patients with chronic hepatitis B with partial virological response

( Dae Hun Kwon ),( In Hee Kim ),( Bum Su Choung ),( Seong Hun Kim ),( Sang Wook Kim ),( Seung Ok Lee ),( Soo Teik Lee ),( Dae Ghon Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-

Background: Partial virological response (PVR) to less potent nucleos(t)ide analogues was associated with risk of antiviral resistance in naive chronic hepatitis B (CHB) patients. However, there were limited data for PVR to more potent drug entecavir (ETV). The objective of this study was to investigate the continuous long-term treatment efficacy of ETV in naive CHB patients with PVR. Methods: This study included 227 naive patients who were treated with ETV 0.5mg for more than 12 months between March 2007 and June 2011. PVR was defined as more than 1 log10 decline of viremia from baseline but a detectable serum HBV DNA by PCR (>20 IU/mL) at week 48. Complete virologic response (CVR) was defined as undetectable serum HBV DNA by PCR (<20 IU/mL) at week 48. Results: At week-48, CVR was 162/227 (71.4%) and PVR was 65/227 (28.6%). HBeAg positivity, baseline serum HBV DNA level (≥8 log10IU/mL), serum HBV DNA at week 12 ≥2,000 IU/mL, serum HBV DNA at week 24 ≥2,000 IU/mL were independently associated with PVR at week 48. Cumulated probabilities of virologic response (<20 IU/mL) at week 96 and 144 in patinets with PVR were 50.9% and 76.2%. In subgroup analysis, patients with PVR and low serum HBV DNA level at week 48 (20-2,0000 IU/mL) showed significantly higher achievement of virologic response at week 96 and 144 than those with PVR and high viral load (≥2,0000 IU/mL) during long-term ETV monotherapy (64.9% vs. 25% and 75.0% vs. 25%, p=0.044). Cumulative probabilities of virological breakthrough at week 96, 144 were 1.6%, 1.6% in patients with CVR and 0%, 5.9% in those with PVR, respectively (p=0.092). However, genotypic resistance was 0% and 5.9% in those with CVR and PVR, respectively (p=0.067) Conclusions: Long-term continuous ETV monotherapy in NA-naive patients with PVR at week 48 could achieve further virologic response without significant antiviral resistance.

Original Article : Long-Term Treatment Efficacy and Safety of Clevudine Therapy in Na?ve Patients with Chronic Hepatitis B

( Bum Su Choung ),( In Hee Kim ),( Byung Jun Jeon ),( Seok Lee ),( Seong Hun Kim ),( Sang Wook Kim ),( Seung Ok Lee ),( Soo Teik Lee ),( Dae Ghon Kim ) The Editorial Office of Gut and Liver 2012 Gut and Liver Vol.6 No.4

Background/Aims: Clevudine (CLV) has potent antiviral activity against chronic hepatitis B (CHB) virus infection. The long-term efficacy and safety of CLV therapy in na?ve patients with CHB were investigated. Methods: In this retrospective study, 152 na?ve Korean patients with CHB who received 30 mg of CLV once daily for at least 12 months were investigated. Results: The cumulative rates at months 12, 24, and 36, respectively, were 65.8%, 74.7%, and 74.7% for undetectable serum hepatitis B virus (HBV) DNA (<12 IU/mL); 77.6%, 86.2%, and 86.2% for normalization of serum alanine aminotransferase (<40 IU/L); 17.6%, 23.5%, and 23.5% for hepatitis B e antigen (HBeAg) loss or seroconversion; and 6.6%, 22.5%, and 30.0% for viral breakthrough. HBeAg positivity (p=0.010), baseline serum HBV DNA level ≥6 log10 IU/mL (p=0.032) and detectable serum HBV DNA (≥12 IU/mL) at week 24 (p=0.023) were independently associated with the development of viral breakthrough. During follow-up, CLV-induced myopathy developed in 5.9% of patients. Conclusions: The results of long-term CLV therapy for the treatment of na?ve patients with CHB showed a high frequency of antiviral resistance and substantial associated myopathy. Therefore, we advise that CLV should not be used as a first-line treatment for na?ve patients given the availability of other more potent, safer antiviral agents. (Gut Liver 2012;6:486-492)

과산화수소 보존표백시 Silicate 대체 약품에 관한 연구

이상헌,정성욱,김성권,류재홍,Michalowski, R J 한국공업화학회 1997 응용화학 Vol.1 No.2

This study was carried out to investigate the effect of the Versenate PS as the peroxide bleach stabilizer in peroxide bleaching system. Currently, but, most peroxide bleach systems contain peroxide, caustic to activate the peroxide, and the use of a stabilizer such as sodium silicate to stabilize the peroxide during the actual bleaching. Therefore, to evaluate he degree to replace sodium silicate, the experiments of metal signature analysis, metal control by chelant(DTPA), caustic level optimization, and the addition of Versenate PS peroxide stabilizer were performed. The results shows that the only combination of Versenate PS and low sodium silicate provide the most effective peroxide bleaching.

口呼吸이 不正咬合에 미치는 影響에 關하여

이미대,장상헌,남동석,서정훈 대한치과의사학회 1992 대한치과의사학회지 Vol.13 No.7

이산화탄소로부터 올레핀 합성을 위한 혼성 촉매와 Fischer-Tropsch 합성 촉매의 비교 연구

이성철,장재훈,서은철,강민철,정석진 한국화학공학회 2003 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.41 No.1

이산화탄소로부터 메탄올을 경유하여 올레핀을 생산하는 연계 공정 대신, 이산화탄소로부터 올레핀을 직접 합성하는 일괄공정을 위하여 두 가지 촉매계를 시험하여 보았다. 즉, 메탄올 합성용 촉매와 메탄올 전환용(Methanol to Olefin process: MTO) 촉매를 혼합하여 구성된 혼성 촉매계와 종래의 Fischer-Tropsch 공정에서 사용되는 철 촉매계를 기반으로 하여 개선된 총매곌르 사용하여 보았다. 일괄 공정 중, 혼성촉매계에서는 Cu/ZnO/Al_2O_3와 Mg-La/ZSM-5로 구성된 혼성촉매가 가장 우수한 이산화탄소 전환 활성을 나타냈으나 구리에 기인한 중간세기 산점의 증대와 강산점의 소멸로 인하여 올레핀의 선택성은 미비하였다. 반면에 종래에 F-T 공정에 사용되는 철 촉매계의 경우 ZSM-5를 담체로 사용하고 특히 알칼리 금속인 K를 조촉매로 사용할 경우 CO_2흡착량을 증가시키게 되며 동시에 촉매 표면에 흡착된 Fe-C종의 결합 강도를 높여 줌으로 인하여 높은 이산화탄소 전환율과 올레핀 선택도를 확보할 수 있었다. One-step conversions of CO_2 into olefins were investigated over conventional Fischer-Tropsch synthesis(FTS) catalyst and the new hybrid catalysts. The hybird catalyst was consisted of methanol synthesis catalyst(Cu/ZnO/Al_2O_3, Cu/ZnO/ZrO_3) and methanol to olefin(MTO) catalyst(Mg-La/ZSM-5). The activity of hybrid catalytic system, which was mixed with Cu/ZnO/Al_2O_3(6:3:1 in weight ratio) and Mg-La/ZSM-5, was superior than others in terms of CO_2 conversion and total hydrocarbon yield, but olefin was not produced significantly. The reason was supposed to be caused by Cu-support interaction, which gives rise to the loss of strong Bro¨nsted acid site and consequently the medium strength acid site production. In contrary to hybrid system, the modified F-T catalytic system showed similar enhanced CO_2 conversion. However, it showed high selectivity to olefin. When ZSM-5 was used as a support for FE-K catalyst system, the selectivity of olefin was found to be increased. The addition of potassium promoters give rise to increase amount of CO_2 uptake on the surface, and the improvement of stability in adsorbed Fe-C species. Consequently, by carefully selecting the support and additives on modified F-T catalyst system, it was possible to obtain the high CO_2 hydrogenation activity as well as high olefin selectivity.

두통과 어지럼증으로 인해 Nedocromil Sodium의 투약을 중단해야 했던 증례 1례

이장훈,소재희,임지연,정지태 대한 소아알레르기 및 호흡기학회 2001 소아알레르기 및 호흡기학회지 Vol.11 No.3

CDFG로 부터 VHDL Subset 추출

김충석(Choung-seok Kim),이영식(Young-sik Lee),표창우(Chang-woo Pyo),원유헌(Yoo-hun Won) 한국정보과학회 1992 한국정보과학회 학술발표논문집 Vol.19 No.1

본 논문에서는 하드웨어 상위수준 합성을 위한 Control and Data Flow Graph 로 부터 VHDL Subset을 생성하는 시스템 설계 및 구현에 관한 논문으로서 지난해의 “VHDL 로부터 CDFG 생성” 연구의 계속된 연구이다. 지난해의 연구인 VHDL로 부터 생성된 CDFG는 CDFG Editor를 거쳐 상위수준 합성을 위해 사용될 수 있다. 이번 연구에서는 Editor를 거쳐 완성된 CDFG를 다시 VHDL로 변환 시켜 봄으로서 생성된 VHDL을 상용화 된 Simulation 도구에서 실행시켜 CDFG를 검증 및 활용할 수 있다. CDFG를 VHDL로 변환하기 위해 parser를 구성 하였으며 parsing된 결과로는 table 형태의 자료구조를 이용하여 VHDL을 생성하였다. 생성된 VHDL은 Structural, Bebavioral 또는 Mixed description 형태의 VHDL Subset 이다. 이러한 연구는 한국전자통신연구소의 지원하에 이루어 지고 있으며 여기서 정의된 CDFG 형태도 ETRI에서 정의된 형태를 사용한다.

X window를 이용한 Schematic Capture System으로 부터 VHDL 생성

김충석(Choung-Seok Kim),이준동(June-Dong Lee),표창우(Chang-Woo Pyo),원유헌(Yoo-Hun Won) 한국정보과학회 1992 한국정보과학회 학술발표논문집 Vol.19 No.1

본 논문에서는 IEEE 표준언어인 VHDL의 사용자 환경에 관한 연구로서 VHDL User Interface를 설계한다. VHDL은 하드웨어 설계분야에서 그 사용이 설계자들 사이에서 점차로 확산되고 있다. 그러나 기존의 Schematic system에 익숙한 설계자 들은 VHDL의 사용에 어려움을 느끼게 되어 회피하는 경향이 있다. 이에 본 연구에서는 기존의 설계 시스템으로 부터 VHDL을 자동생성 함으로서 사용자에게 편리한 VHDL 인터페이스 환경을 제공하여 기존의 Schematic 설계 시스템과 VHDL 사이의 교량 역할을 하는 시스템을 설계한다. 이렇게 생성된 VHDL은 VHDL 지원환경의 각종 tool에서 유용하게 사용될 수 있다. 본 연구에서는 우선 UNIX 환경하에서 사용할 수 있게 하기 위해 X Window를 이용하여 Schematic Capture System을 구성하였으며 이 시스템 으로 부터 VHDL을 생성하는 시스템을 설계하여 보았다.