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Improving the Sensitivity of a High-Tc SQUID Magnetometer with a Serial Array
Chiu-Hsien Wu,Hong-Chang Yang,J. C. Chen,C. T. Chiang,C. Y. Chen,Herng-Er Horng,J. T. Jeng,K. L Chen,M. J. Chen 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.48 No.5I
To pursue a high-reproducibility and high-quality SQUID for high-Tc superconducting applications, we have designed and fabricated a flip-chip magnetometer as a sensor for measuring weak magnetic signals. The magnetometer consists of a serial SQUID magnetometer coupled to a flux focuser. The SQUIDs are connected in series, thereby increasing the peak-to-peak value of the voltage-flux transfer function, V. A flux focuser is employed to increase the effective area of the SQUID. The serial SQUID array has high-quality device characteristics. High-Tc SQUID magnetometers exhibiting a magnetic field sensitivity of 45 fT/Hz1/2 in the white region and 200 fT/Hz1/2 at 1 Hz have been demonstrated in this work. The flip-chip SQUID magnetometer shows a sufficiently high sensitivity to record magnetocardiograms.
Three methods for studying coupled vibration in a multi flexible disk rotor system
YiJui Chiu,Xiao-Yun Li,Yi-Cheng Chen,Sheng-Rui Jian,Chia-Hao Yang,I-Hsiang Lin 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.11
This paper improved and developed Shaft-disk-blade (SDB) rotor system based on the previous studies of the authors in the last decade from Yang and Huang (2005) to Chiu et al. (2017). This paper also explored blade-bending, disk-transverse, and shaft-torsion coupling vibration of a multi flexible disk rotor system. Unlike the previous studies of the authors, this paper adopted three methods: (a) Assumed mode method (AMM), (b) Finite element method (FEM), and (c) experimental method. The first approach is the main method, and the two other methods are complementary. Results generated from the three methods were then compared and analyzed. Based on the previous definition of the authors, a flexible disk rotor system displays three types of coupling vibrations: Inter-blade, SDB, and diskblade modes. The system changes the rules of natural frequencies and mode shapes. This paper presents several interesting results. First, the author determined the change rules of the mode shapes and natural frequencies using the AMM, FEM (including three kinds of software), and the experimental method. Second, numerical calculation results also revealed that two phenomena regarding the distance of disk and flexible disk would be affected by the natural frequencies. Third, the experimental results would be explored in this paper. Last, the flexible disk could affect the system instability in the case study of rotation effects.
Tzu-Chau Chen,Chao-Tsai Huang,Yan-Chen Chiu,Wei-Da Wang,Cheng-Li Hsu,Chen-Yang Lin,Lung-Wen Kao 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
Runner system plays a very important role in injection molding process. A quality runner design is helpful in improving product qualities and saving material. However, traditional cold runner systems have certain inherent issues. Moreover, poor product cosmetics are commonly seen with the use of traditional cold runners. As a result, hot runner technology has been widely applied. On the other hand, It has been one of the green molding solutions for material/energy saving and clean environments. But the mechanism behind the hot runner system is too complicated to be fully understood. There exist some critical issues currently. As a result, the simulation technolgy is highly needed to examine hot runner designs before the real manufacturing. Through simulation analyses, designers and manufafctuers are able to catch the potential issues on their hot runner systems and revise their designs. Hot runner simulation technology helps with the investigations into the behavior in hot runner system. In this paper, a true 3D numerical method is proposed and applied to investigate the temperature behavior in a real hot runner system for PC material. The experiment is conducted and the simulating result is compared with that from the experiment for the validation purpose.
Tsung-Hua Lu(Tsung-Hua Lu),Shih-Hsien Lin(Shih-Hsien Lin),Huai-Hsuan Tseng(Huai-Hsuan Tseng),Yen Kuang Yang(Yen Kuang Yang),Nan Tsing Chiu(Nan Tsing Chiu),Po See Chen(Po See Chen) 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.4
Objective: Bipolar disorder (BD) is characterized by the poor sleep quality. Whether the striatal dopamine transporter (DAT) availability is related to sleep quality among patients with BD is unclear. Methods: Fifty-three euthymic patients with BD (24 BD-I and 29 BD-II) and sixty-eight healthy controls were enrolled. The Chinese Version of the Pittsburgh Sleep Quality Index (PSQI) was used, and the availability of DAT was assessed by single-photon emission computed tomography (SPECT) using [99mTc] TRODAT-1. Results: The sleep disturbance component of the PSQI was significantly associated with the level of DAT availability among patients with BD. Conclusion: The striatal dopaminergic activity that contributes to resilience to adversity was associated with sleep pattern among patients with BD.
Chiu-Huang Ting,Chia-Ying Lin,Yang-Chieh Huang,Shyh-Shyan Liu,Shao-Yu Peng,Chen-Wei Wang,Hung-Yi Wu 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.1
Background: Goslings in several Taiwanese farms experienced gosling feather loss disease (GFL) at 21–35 days and goose broke feather disease (GBF) at 42–60 days. The prevalence ranges from a few birds to 500 cases per field. It is estimated that about 12,000 geese have been infected, the morbidity is 70–80% and the mortality is 20–30%. Objectives: This study aims to investigate the pathogens that cause GFL and GBF. Focus on the study of the correlation between goose circovirus (GoCV) and goose parvovirus (GPV) with the goose feather loss in southern Taiwan. Furthermore, a phylogenetic tree was established to align the differences between southern and northern Taiwan and compare with virus strains from China and Europe. Methods: Samples were collected from animal hospitals. Molecular and microscopy diagnostics were used to examine 92 geese. Specific quantitative polymerase chain reaction (Q-PCR) assays are performed to evaluate GPV and GoCV viral loads and simultaneously evaluated the feather loss conditions in geese with the scoring method. Results: High prevalence of GoCV and GPV infection in geese showing signs of GFL and GBF. Inclusion body was detected in the feather follicles and Lieberkühn crypt epithelial cells. The Q-PCR showed the high correlation between feather loss and viruses during 3rd–5th week. However, the infection was not detected using the same test in 60 healthy geese. Conclusions: Thus, GFL and GBF appear to be significantly closely related to GoCV and GPV. The geese feathers showed increasing recovery after being quarantined and disinfected.
Research on effect of rings on coupling vibration in a rigid-disk rotor
YiJui Chiu,Xiao-Yun Li,Guo-Fei Yu,Chia-Hao Yang,Jeng-Shyang Pan,ChinLing Chen 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.2
This paper uses new deductions of the equation of motion and obtains new modes of change that differ from the authors’ previous research. The blade-bending, shaft-torsion and ringbending coupled vibration influence of a single-disk rotor whose blade subsystem was coated with a ring is investigated. In the last two years, the authors adopted two methods, the assumed mode method and finite element method, and compared both parties results. This article continues that work. In this paper, the phenomena of ring joint coupling vibrations are different and interesting. The authors defined two new types, the shaft-blade-ring (SBR) and blade-ring (BR) modes. These two coupling modes can be mutually affected by the shaft, blade, and ring, and no single subsystem predominates. The new change rules of natural frequencies of rotors with two to 15 blades and those of mode shapes are discussed. The influence of the ring thickness and rotational speed are also studied in this paper.
Hung-An Chen,Chun-Ching Chiu,Chih-Yang Huang,Li-Jeng Chen,Chun-Chou Tsai,Tsai-Ching Hsu,Bor-Show Tzang 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.7
Lactoferrin (LF) has beneficial effects against various diseases. However, the effects of LF on liver fibrosis in systematic lupus erythematosus (SLE) are unknown. In this study, NZB/W F1 mice were utilized to investigate the effects of LF on SLE. Experiments reveal that LF significantly increases glutathione and 1,1-diphenyl-2-picryl-hydrazyl levels and significantly decreased malondialdehyde levels in both serum and liver in NZB/W F1 mice. LF also lowered matrix metalloproteinase-9 activity and liver inflammatory indices, such as aminotransferase and alanine aminotransferase. Notably, significantly decreased expression of fibrotic related molecules, including transforming growth factor (TGF)-β1, tumor necrosis factor-α, interleukin-1β, and TGF-β1 receptor, were observed in the livers of NZB/W F1 mice that had been treated with LF. Significantly, suppressed Smad2/3 signaling, α-smooth muscle actin, and collagen deposition were also detected. These findings reveal that LF has beneficial effects on SLE by increasing antioxidant activities and ameliorating liver inflammation and fibrosis, suggesting the therapeutic effectiveness of LF against SLE.
Resonant-Frequency-Dependent Flux Noise of a High-TC rf SQUID Coupled to a Substrate Resonator
Ji-Cheng Chen,Hong-Chang Yang,Chiu-Hsien Wu,Herng-Er Horng,Jen-Tzong Jeng,Kuen-Lin Chen 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.48 No.5I
In the recent development of a high-TC rf SQUID magnetometer, Zhang et al. used a SrTiO3 substrate resonator with a YBCO thin film flux concentrator on it. The effective area was improved by a flux concentrator. However, there was no study of the resonant frequency of the substrate resonator. In this work, the frequency-dependent flux noise of a high-TC rf SQUID coupled to a substrate resonator was investigated. The results were analyzed with the noise theory. The optimization of the SQUID with a substrate resonator and its flux noise are discussed.