Cellulitis in Broiler Chickens

AMER, Mohamed M.,MEKKY, Hoda M.,FEDAWY, Hanaa S.,AMER, Aziza M.,ELBAYOUMI, Khalid M. Korea FoodHealth Convergence Association 2020 식품보건융합연구 (KJFHC) Vol.6 No.5

Cellulitis in broiler chickens is one of the economically important problems that facing the broiler industry due to the presence of the lesion leads to condemnation of part of /or the entire carcasses. Broiler with cellulitis lesions showed lower body weight. Cellulitis was recorded on different body regions including the head, dorsum, thighs, breast, legs, and abdomen. Cellulitis results from the invasion of subcutaneous (s.c.) tissues by bacteria through disruption of skin integrity. Lesions revealed the existence of the characteristic s.c colored exudate varies from yellowish to green, which were either serosanguineous, fibrinous s.c exudate yellowish, greenish or suppurative. Many bacterial isolates including E. coli, Staphylococci, Clostridia, Aeromonas spp., Enterobacter spp., Proteus mirabilis, P. aeruginosa, and Streptococci were isolated from the lesion. Chickens exposed to immunosuppression proved to have a greater probability of developing cellulitis. The condition was experimentally induced by s.c inoculation of 25-day-old broiler chickens with E. coli, S. aureus and clostridia. Usually, bacterial isolates were multidrug-resistant. The usage of Bifidobacterium bifidum or antibiotic with avoiding immunosuppression can reduce lesion and condemnation rate resulted from cellulitis. The objective of this review is to collect different literature written about cellulitis to be available to students, researchers, and veterinarians in poultry practical.

Gastric cancer in pregnancy

Amer Saeed Alshahrani,Moon-Won Yoo 대한외과학회 2017 Annals of Surgical Treatment and Research(ASRT) Vol.92 No.1

Anterolateral Cervical Kyphoplasty for Metastatic Cervical Spine Lesions

Amer Sebaaly,Ahmed Najjar,Zhi Wang,Ghassan Boubez,Laura Masucci,Daniel Shedid 대한척추외과학회 2018 Asian Spine Journal Vol.12 No.5

Study Design: Retrospective case series. Purpose: To evaluate the clinical and radiological efficacy of anterolateral kyphoplasty for cervical spinal metastasis. Overview of Literature: Although the spine is the third most common site of tumor metastasis, the cervical spine is the least commonly affected (incidence, 10%–15%). Surgical decompression is highly challenging because of the proximity of neural and vascular elements. Kyphoplasty for cervical spine metastasis has been described in small case reports with promising results. Methods: Retrospective analysis of a prospective collected single-center spine metastasis database was done for cervical kyphoplasty cases. Data pertaining to age, sex, primary tumor diagnosis, modified Tokuhashi score, Spinal Instability Neoplastic Score (SINS), preoperative Visual Analog Scale (VAS) score, and analgesic medication were extracted. Postoperative data included VAS score at postoperative day 1, duration of hospitalization, self-reported functional outcome, and VAS score at the last follow-up. Results: Eleven patients (mean age, 62.5 years) with cervical spine metastases were treated with 15-level kyphoplasty. Mean Tokuhashi score was 8.1, and mean SINS was 7.85. Mean preoperative pain score was 7.1, and 82% of patients used opioid analgesics. Mean total bleeding volume was 100 mL. Mean complication-free length of stay was 2.6 days with a decrease in postoperative pain (VAS score=2.8, p <0.05). There was a 56% decrease in opioid dosage and the number of consumed analgesics (1.09, p =0.004). Eightytwo percent of the patients reported excellent improvement at the last follow-up self-assessment. Conclusions: To our knowledge, this case series represents the largest series of vertebral augmentation using balloon kyphoplasty for cervical spinal metastasis. This technique is associated with low postoperative complications as well as significant decrease in pain, use of opioids, and length of hospital stay. The main indications for vertebral kyphoplasty are lytic lesions of the cervical spine, painful lesions refractory to medical treatment, SINS score of 6–10, and absence of posterior wall defect.

Size-dependent plastic buckling behavior of micro-beam structures by using conventional mechanism-based strain gradient plasticity

Amer Darvishvand,Asghar Zajkani 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.71 No.3

Since the actuators with small- scale structures may be exposed to external reciprocal actions lead to create undesirable loads causing instability, the buckling behaviors of them are interested to make reliable or accurate actions. Therefore, the purpose of this paper is to analyze plastic buckling behavior of the micro beam structures by adopting a Conventional Mechanism-based Strain Gradient plasticity (CMSG) theory. The effect of length scale on critical force is considered for three types of boundary conditions, i.e. the simply supported, cantilever and clamped - simply supported micro beams. For each case, the stability equations of the buckling are calculated to obtain related critical forces. The constitutive equation involves work hardening phenomenon through defining an index of multiple plastic hardening exponent. In addition, the Euler-Bernoulli hypothesis is used for kinematic of deflection. Corresponding to each length scale and index of the plastic work hardening, the critical forces are determined to compare them together.

Establishing National Science and Technology Park in Pakistan

Amer Hashmi,Ali Shah 세계과학도시연합 2013 World Technopolis Review Vol.1 No.4

This paper presents the concept of the National Science and Technology Park (NSTP) in Islamabad, Pakistan. Keeping in line with Karl Popper’s Piecemeal Social Engineering theory, a critical-pragmatic approach is adopted in shedding light on the strategic thrusts and expected outcomes of this knowledge-driven, entrepreneurially-spirited, multi-industry project. Based on Triple-Helix perspectives, we investigate the role of the National University of Sciences and Technology, Islamabad in efforts aimed at developing NSTP as an intermediary hybrid organization that enhances industry-academia-government linkages, with the potential to serve as an engine for regional and national economic growth and competitiveness.

Cultural Tourism

Amer Rghei 세계문화관광학회 2009 Conference Proceedings Vol.10 No.0

The Sahara region is potentially, for tourists, one of the most attractive areas in the world. Yet currently, the Sahara is underdeveloped for tourism and neglected by local governments and tourists. In contrast, the nearby Mediterranean region receives millions of visitors annually from across the globe. The Sahara, with areas of unique resources, is of special interest in terms of tourism planning and economic developrnent. The focus of this study is the Sahara's areas and sites of unique resources that have fallen into a serious state of decline and neglect despite their tourism potential. These deteriorated resources, observed in several field tours of historic sites, their historical, educational, economic social, cultural, environmental and aesthetic values would benefit from careful planning and management for tourism. This paper will investigate this issue and propose a new strategy for tourism development for the Sahara.

Ultrafast All-Optical Logic OR Gate Based on Two-photon Absorption with a Semiconductor Optical Amplifier-assisted Delayed Interferometer

Amer Kotb 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.2

The performance of an all-optical logic OR gate is numerically studied and simulated. This Boolean operation is realized by using a semiconductor optical amplifier (SOA) and a delayed interferometer (DI) based on two-photon absorption (TPA). The input pulse intensities are high enough so that the two-photon-induced phase change is larger than the regular gain-induced phase change. The study is carried out with the effect of the amplified spontaneous emission (ASE) taken into account in the simulation analysis. The dependence of the output quality factor (Q-factor) on the data signals and SOA’s parameters is also investigated and discussed. The achieved results show that the OR gate is capable of operating at a data speed of 250 Gb/s with logical correctness and proper Q-factor.

Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway

Amer Ali Abd El-Hafeez,Hala Mohamed M. Marzouk,Mohamed A. A. Abdelhamid,Hazim O. Khalifa,Tamer H. A. Hasanin,Ahmed G. K. Habib,Fatma Mahmoud Abdelwahed,Fatma M. Barakat,Eslam M. Bastawy,Eman M. B. Abd 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.5

Hyoscyamus muticus L. is a traditional medicine used as antispasmodic and sedative. Herein, we aimed to determine the phytochemical constituents and for the first time its anti-cancer activities. The phytochemical constituents of the different extracts were evaluated by calorimetric methods. The anti-cancer activities of the extracts were tested against leukemia, breast, renal, and prostate cancers cell lines. 4, 6-Diamidino-2-phenylindole (DAPI) staining, flow cytometric analysis, knockdown of ASK1, and reactive oxygen species (ROS) production were evaluated to clarify the mechanism of action. Phytochemical screening confirmed the presence of wide range of phytoconstituents. Hyoscyamus muticus methanolic extracts (HMME) showed the highest anti-cancer activities against leukemia, breast, renal, and prostate cancers as compared to ethanol and aqueous extracts. Specifically, HMME exerted cytotoxic effect against the MDA-MB-231 and MDA-MB-468 triple-negative breast cancer (TNBC) cell lines with IC50 values of 8.75 and 7.25 μg/mL, respectively. Mechanistically, DAPI staining and flow cytometric analysis revealed that HMME induces apoptosis via the death receptor, FAS, but not the mitochondrial pathway. Moreover, ASK1 and p38 were rapidly activated in response to HMME, and knockdown of ASK1 by a small interference of RNA specific to Ask1 attenuated p38 and caspase-3 activation and suppressed apoptosis, implying that HMME-induced apoptosis relies on the ASK1-p38-caspase-3 pathway. Furthermore, we confirmed that cellular ROS generation was a critical mediator in HMME-induced apoptosis because the ROSscavenger N-acetyl cysteine significantly decreased the phosphorylation of ASK1 and HMME-induced apoptosis. Our results confirmed HMME cytotoxic effects in TNBCs via ROS-dependent activation of the Fas/FasL-ASK1-p38 axis.

Small dose of naloxone as an adjuvant to bupivacaine in intrapleural infiltration after thoracotomy surgery: a prospective, controlled study

Amer, Asmaa Fawzy,Omara, Amany Faheem The Korean Pain Society 2019 The Korean Journal of Pain Vol.32 No.2

Background: Severe pain always develops after thoracotomy; intrapleural regional analgesia is used as a simple, safe technique to control it. This study was performed to evaluate whether a small dose of naloxone with local anesthetics prolongs sensory blockade. Methods: A prospective, randomized double-blinded controlled study was conducted on 60 patients of American Society of Anesthesiologists statuses I and II, aged 18 to 60 years, scheduled for unilateral thoracotomy surgery. After surgery, patients were randomly divided into two groups: through the intrapleural catheter, group B received 30 ml of 0.5% bupivacaine, while group N received 30 ml of 0.5% bupivacaine with 100 ng of naloxone. Postoperative pain was assessed using the visual analog pain scale (VAS). Time for the first request for rescue analgesia, total amount consumed, and incidence of postoperative complications were also recorded. Results: The VAS score significantly decreased in group N, at 6 h and 8 h after operation (P < 0.001 for both). At 12 h after injection, the VAS score increased significantly in group N (P < 0.001). The time for the first request of rescue analgesia was significantly longer in group N compared to group B (P < 0.001). The total amount of morphine consumed was significantly lower in group N than in the bupivacaine group (P < 0.001). Conclusions: Addition of a small dose of naloxone to bupivacaine in intrapleural regional analgesia significantly prolonged pain relief after thoracotomy and delayed the first request for rescue analgesia, without significant adverse effects.

Simulation of All-optical Logic NOR Gate Based on Two-photon Absorption with Semiconductor Optical Amplifier-assisted Mach-Zehnder Interferometer with the Effect of Amplified Spontaneous Emission

Amer Kotb 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.66 No.10

The performance of an all-optical NOR gate is numerically simulated and investigated. The NOR Boolean function is realized by using a semiconductor optical amplifier (SOA) incorporated in Mach- Zehnder interferometer (MZI) arms and exploiting the nonlinear effect of two-photon absorption (TPA). If the input pulse intensities is adjusting to be high enough, the TPA-induced phase change can be larger than the regular gain-induced phase change and hence support ultrafast operation in the dual rail switching mode. The numerical study is carried out by taking into account the effect of the amplified spontaneous emission (ASE). The dependence of the output quality factor (Q-factor) on critical data signals and SOAs parameters is examined and assessed. The obtained results confirm that the NOR gate implemented with the proposed scheme is capable of operating at a data rate of 250 Gb/s with logical correctness and high output Q-factor.