Quality of life following surgical treatment of oral cancers

Akinwale Adeyemi Efunkoya,Raphael Adetokunbo Adebola,Kelvin Uchenna Omeje,Ibiyinka Olushola Amole,Benjamin Idemudia Akhiwu,Daniel Otasowie Osunde 대한구강악안면외과학회 2015 대한구강악안면외과학회지 Vol.41 No.1

Objectives: Quality of life (QoL) studies provide information about the impact of disease, the treatment of symptoms, and outcomes following treatment. The present study aims to evaluate the postoperative QoL of patients treated for oral cancer in a Nigerian government tertiary hospital. Materials and Methods: A prospective study on consenting patients with oral cancer was undertaken at Aminu Kano Teaching Hospital, Kano, Ni- geria. The subjects completed the University of Washington QoL (UW-QoL) questionnaire one day prior to surgery and postoperatively after 7 days, 1 month, 3 months, and 6 months. Results: Sixty-eight patients with oral cancer were recruited. Of these, 38 were males, and 30 were females (male : female, 1.3 : 1). Twenty-four pa- tients (12 males and 12 females) underwent surgery and completed postoperative QoL assessment using the UW-QoL questionnaire. Preoperative QoL mean score was 2.21, while postoperative mean scores after 1 week, 1 month, 3 months, and 6 months were 3.67, 3.46, 2.82, and 2.61, respectively. Conclusion: An improvement in QoL following surgical treatment for patients with oral cancer was observed. ‘Appearance,’ ‘recreation,’ and ‘chewing’ were identified as the most important determinants of postoperative QoL in patients with oral cancer in our study.

Trajectory of brain-drain and quality of work-life amongst Nigeria’s university lecturers: academic staff union of universities (ASUU) incessant strike in retrospect

Akinwale Olusegun Emmanuel,Kuye Owolabi Lateef,Akinwale Olayombo Elizabeth 경희대학교 글로벌 통상·금융연구원 2023 International Trade, Politics and Development Vol.7 No.2

Brain-drain insurgency has become pervasive amongst professionals and the last option for everyone in the country to realise a sustainable quality of work-life (QWL). All youths now in the country have perceived migrating to the international workspace as a noble idea. This study investigates the incidence of brain-drain and QWL amongst academics in Nigerian universities.To sparkle a clearer understanding concerning factors preventing the QWL amongst Nigeria's lecturers, this study utilised a cross-sectional research design to survey the participants across all departments in federal institutions through an explanatory research approach. This study applied an array of adapted scales to evaluate members of academic staff track of what provoked the incidence of brain-drain amongst Nigerian lecturers and possible influence on their QWL. The study surveyed 431 members of academic staff in Nigerian universities to collect useful data and employed a structural equation model (SEM) to analyse the obtained data.The outcome of this study highlights that there is a horrible condition of service amongst Nigerian lecturers, a poor compensation system, poor academic research funding and lack of autonomy are bane to the QWL experienced in Nigerian tertiary institutions today. This study indicates that poor staff development and inadequate university funding are part of the justification that provoked brain-drain insurgence, and allowed the government to lose their skilled and competent egg-heads in the university to other foreign nations of the world.This study demonstrated that brain-drain has become part of Nigeria's national life given that all professionals are seeking better life where their skills, competence and energy would be valued. Brain-drain was not common until these days amongst academics and fewer studies were noted but this study showed a novel paradigm regarding the QWL and brain-drain trajectory.

Snoring Sound Classification Using 1D-CNN Model Based on Multi-Feature Extraction

Tosin Akinwale Adesuyi,Byeong Man Kim,Jongwan Kim 한국지능시스템학회 2022 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.22 No.1

Sound is an essential element of human relationships and communication. The sound recognition process involves three phases: signal preprocessing, feature extraction, and classification. This paper describes research on the classification of snoring data used to determine the importance of sleep health in humans. However, current sound classification methods using deep learning approaches do not yield desirable results for building good models. This is because some of the salient features required to sufficiently discriminate sounds and improve the accuracy of the classification are poorly captured during training. In this study, we propose a new convolutional neural network (CNN) model for sound classification using multi-feature extraction. The extracted features were used to form a new dataset that was used as the input to the CNN. Experiments were conducted on snoring and non-snoring datasets. The accuracy of the proposed model was 99.7% for snoring sounds, demonstrating an almost perfect classification and superior results compared to existing methods.

two-year audit of non-vascularized iliac crest bone graft for mandibular reconstruction: technique, experience and challenges

Kelvin Omeje,Akinwale Efunkoya,Ibiyinka Amole,Benjamin Akhiwu,Daniel Osunde 대한구강악안면외과학회 2014 대한구강악안면외과학회지 Vol.40 No.6

Objectives: Non-vascularized iliac crest bone graft (NVIBG) is a known treatment option in mandibular reconstruction following jaw resection, but no documented review of patients treated with NVIBG exists for northern Nigeria. The experience and technique from a Nigerian tertiary hospital may serve as baseline data for comparison and improvement of practice for other institutions. Materials and Methods: A retrospective review of medical records and patient case files from January 2012 to December 2013 was undertaken. All case files and other medical records of patients who had reconstruction with NVIBG for benign or malignant lesions with immediate or delayed recon- struction were selected for review. Results: Twenty patients had mandibular reconstruction with NVIBG during the study period. Two patients were excluded because of incomplete medical records. Eighteen patients’ (male=14, female=4) records were reviewed. Their ages ranged from 13 to 62 years (mean 26.0±10.6 years). Indications for NVIBG included jaw tumors (n=16; 88.3%), jaw cyst (n=1; 5.6%) and gunshot injury (n=1; 5.6%). Jaw tumors seen were ameloblastoma (n=15; 83.3%) and osteosarcoma (n=1; 5.6%). Treatments done were mandibular resection with condylar resection (n=7; 38.9%), mandibular segmen- tal resection (n=10; 55.6%) and subtotal mandibulectomy (n=1; 5.6%). Patients’ postoperative reviews and radiographs revealed good facial profile and continued bone stability up to 1 year following NVIBG. Conclusion: NVIBGs provide an acceptable alternative to vascularized bone grafts, genetically engineered bone, and distraction osteogenesis for mandibular reconstruction in resource-limited centers.

Beyond SARS-CoV-2: Lessons That African Governments Can Apply in Preparation for Possible Future Epidemics

Mary Aigbiremo Oboh,Semeeh Akinwale Omoleke,Christian Eseigbe Imafidon,Olumide Ajibola,Eniyou Cheryll Oriero,Alfred Amambua-Ngwa 대한예방의학회 2020 Journal of Preventive Medicine and Public Health Vol.53 No.5

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has placed unprecedented pressure on healthcare systems, even in advanced economies. While the number of cases of SARS-CoV-2 in Africa compared to other continents has so far been low, there are concerns about under-reporting, inadequate diagnostic tools, and insufficient treatment facilities. Moreover, proactiveness on the part of African governments has been under scrutiny. For instance, issues have emerged regarding the responsiveness of African countries in closing international borders to limit trans-continental transmission of the virus. Overdependence on imported products and outsourced services could have contributed to African governments’ hesitation to shut down international air and seaports. In this era of emerging and re-emerging pathogens, we recommend that African nations should consider self-sufficiency in the health sector as an urgent priority, as this will not be the last outbreak to occur. In addition to the Regional Disease Surveillance Systems Enhancement fund (US$600 million) provided by the World Bank for strengthening health systems and disease surveillance, each country should further establish an epidemic emergency fund for epidemic preparedness and response. We also recommend that epidemic surveillance units should create a secure database of previous and ongoing pandemics in terms of aetiology, spread, and treatment, as well as financial management records. Strategic collection and analysis of data should also be a central focus of these units to facilitate studies of disease trends and to estimate the scale of requirements in preparation and response to any future pandemic or epidemic.

Vulnerability Analysis Approach To Capturing Information System Safety Threats and Requirements

Oluwasefunmi,Arogundade,Adio,Akinwale,Zhi,Jin,Xiaoguang,Yang 보안공학연구지원센터 2011 International Journal of Software Engineering and Vol.5 No.4

Vitamin E, Phospholipid, and Phytosterol Contents of Parkia biglobosa and Citrullus colocynthis Seeds and Their Potential Applications to Human Health

Ayomadewa Mercy Olatunya,Akinwale Omojola,Kolawole Akinpelu,Emmanuel Temitope Akintayo 한국식품영양과학회 2019 Preventive Nutrition and Food Science Vol.24 No.3

Vitamin E, phytosterol, and phospholipids are classes of lipids that are also referred to as nutraceuticals. These lipids are components of foods, which have nutritional as well as numerous other health benefits, and consumption has been shown to prevent certain deadly diseases. These compounds can only be obtained from plant products; there is therefore a need for more research on the availability of these compounds from common food sources. Oils extracted from Citrullus colocynthis and Parkia biglobosa seeds were analysed for vitamin E, phospholipid, and phytosterol contents using a chromatographic technique. The seeds had total vitamin E contents of 53.47 and 42.57 mg/100 g, phytosterol contents of 260 and 451 mg/100 g, and phospholipid contents of 409 and 1,603 mg/100 g for C. colocynthis and P. biglobosa, respectively. Thus, consumption of these two plants as condiments will help people consume these essential lipids and could serve as dietary supplements to prevent and combat occurrence of certain deadly diseases; this is important as the world is revolving towards disease prevention rather than curing, which is often more expensive and difficult.

Long-term survival of children following acute peritoneal dialysis in a resource-limited setting

( Michael Abel Alao ),( Olayinka Rasheed Ibrahim ),( Adanze Onyenonachi Asinobi ),( Akinwale Akinsola ) 대한신장학회 2020 Kidney Research and Clinical Practice Vol.39 No.4

Background: There is a paucity of data on long term-outcomes of children who undergo acute peritoneal dialysis (PD) in resource-limited settings. We reviewed the outcomes of children who underwent PD after 18 months of follow-up. Methods: We conducted a prospective cohort study in children with acute kidney injury (AKI) who underwent PD. Diagnosis of AKI was based on the 2012 Kidney Disease: Improving Global Outcomes definition. We assessed outcomes of in-hospital mortality, 18-month post-dialysis survival, factors associated with survival, and progression to chronic kidney disease (CKD). Results: Twenty-nine children with a median age of 6 (3 to 11) years underwent acute PD. In-hospital mortality was 3/29 (10.3%) and rose to 27.6% during follow-up. Seven (24.1%) children were lost to follow-up. Of the 14 remaining children, six (42.9%) experienced full recovery of renal function, while eight (57.1%) progressed to CKD. Among those who experienced full recovery, median (interquartile range) estimated glomerular filtration rate (eGFR) rose from 12.67 (7.05, 22.85) mL/min/1.73 m² to 95.56 (64.50, 198.00) mL/min/1.73 m², P = 0.031. No significant changes in median eGFR from baseline were observed among those who progressed to CKD (P = 0.383) or in non-survivors (P = 0.838). According to Kaplan-Meier curve analyses, 18-month survival during follow-up was 66.0% (95% CI, 45.0% to 86.5%). Age < 5 was associated with greater likelihood of survival (OR, 3.217; 95% CI, 1.240 to 8.342). Conclusion: Progression of post-PD AKI to CKD occurred in more than half of survivors. Age < 5 was associated with greater likelihood of survival.

Protective effect of methanol leaf extract of Cnidoscolus aconitifolius against lipopolysaccharides-induced cortico-hippocampal neuroinflammation, oxidative stress and memory impairment

Kabirat Temitope Babalola,Oyetola Oyebanjo,Victor Adetayo Adekoya,Ismaheel Akinwale Adeniyi,Abayomi Mayowa Ajayi,Samuel Adetunji Onasanwo 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.1

Cnidoscolus aconitifolius contains various phenolic compounds possessing anti-inflammatory and antioxidant properties. This study aimed to evaluate the protective effect of the Methanol Extract of Cnidoscolus aconitifolius (MECA) against LPS-induced memory impairment, oxidative stress and neuroinflammation in rats. Thirty male Wistar rats were divided into 5 groups (n = 6). Group 1 served as the control and received the vehicle, group 2 was negative control, groups 3–5 received MECA (25, 50, and 100 mg/kg) for 14 days. Groups 2–5 were daily injected with LPS (250 μg/kg, i.p) from day 8–14 of treatment. Memory impairment was evaluated after the last LPS administration using the Y-Maze Test (YMT) and Novel Object Recognition Test (NORT). Brain prefrontal cortex (PFC) and hippocampus (HPC) sections were obtained and levels of reduced glutathione (GSH), malondialdehyde, catalase, nitrite, acetylcholinesterase, and TNF-α and IL-6 were determined. Oral administration of MECA significantly reversed LPS-induced memory impairment in the YMT and NORT. MECA significantly reduced LPS-induced elevated malondialdehyde and nitrite, while preventing depletion of GSH and catalase in the PFC and HPC sections of the brain. Acetylcholinesterase activity is also reduced. MECA (100 mg/kg) significantly reduced IL-6 and TNF-α levels in PFC and HPC of LPS-treated rats. This study showed that the methanol extract of Cnidoscolus aconitifolius has significant protective effect against lipopolysaccharide-induced memory impairment via mechanisms related to inhibition of neuroinflammation and oxidative stress.