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New bioactive aromatic compounds from Vismia guianensis
Seo, Eun-Kyoung,Wani, Mansukh C.,Wall, Monroe E.,Navarro, Hernan,Mukherjee, Rabindranath,Farnsworth, Norman R.,Kinghorn, A. Douglas 梨花女子大學校 藥學硏究所 2000 藥學硏究論文集 Vol.- No.9
Five benzophenones, vismiaguianones A-E, and two benzocoumarins, vismiaguianins A and B were isolated from the CHCl_3 extract of the roots of Vismia guianensis by bioassay-directcd fractionation using the DNA strand-scission assay and KB cell line. Of the isolates obtained, vismiaguianone B exhibited DNA strand-scission activity, whereas vismiaguianones D and E and vismiaguianin A were found to be significantly cytotoxic.
New IAEA Actinide Decay Data Library
M. A. Kellett,M-M. Be,V. Chechev,Xiaolong Huang,F. G. Kondev,A. Luca,G. Mukherjee,A. L. Nichols,A. Pearce 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
A recently completed IAEA Coordinated Research Project (CRP) entitled ``Updated Decay Data Library for Actinides'' has resulted in new and comprehensive evaluations of the decay scheme data for over forty nuclear-power related actinides, along with a further forty radionuclides that arise from their natural decay. A number of data inadequacies remain despite a series of well-defined measurements being undertaken under the auspices of this CRP, which were subsequently incorporated into the relevant evaluations. A list is given of these outstanding measurement requirements as identified from observed shortcomings in the available data. The final data library is available in two standard formats: ENSDF for use in nuclear structure studies, and ENDF for nuclear plant applications including design and operation. Evaluations were undertaken by following the precise methodology of the Decay Data Evaluation Project (DDEP) to ensure that a uniform approach was applied by all participants. The library and associated documentation are available from a dedicated IAEA webpage (http://www-nds.iaea.org/act\textunderscore ddl/).
Mass Chain Evaluation for A = 95
Swapan Kr. Basu,Gopal Mukherjee,A. A. Sonzogni 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
A full evaluation of the mass chain A = 95 has been done in the ENSDF format taking into account all the available data until June 2009. Excited states populated by in-beam nuclear reactions and by radioactive decay have been considered. The "evp" editor, developed at the NNDC, has been used for the evaluation. This mass chain was last evaluated in 1993. Many new and improved data were reported since then. A total of 13 nuclei have been evaluated.
Simulation and experimental analysis of the clamping pressure distribution in a PEM fuel cell stack
Bates, A.,Mukherjee, S.,Hwang, S.,Lee, S.C.,Kwon, O.,Choi, G.H.,Park, S. Pergamon Press ; Elsevier Science Ltd 2013 International journal of hydrogen energy Vol.38 No.15
High performance and efficiency are often reported in single-cell polymer electrolyte membrane (PEM) fuel cell (FC) experiments. This however, can reduce substantially when moving from single-cell experiments to multiple cells. Fuel cell performance is degraded for many reasons when adding cells, but; possibly the most important, is contact resistance between the bipolar plate and gas diffusion layer (GDL). Contact resistance is in direct relation to the clamping configuration and clamping pressure applied to a FC stack. Simulation of a single cell and 16-cell FC was performed at various clamping pressures resulting in detailed 3D plots of stress and deformation. The stress on the GDL, for any value of clamping pressure simulated in this study, is around 1.5 MPa for the 16-cell stack and around 4 MPa in single cell simulations. Experimental testing of clamping pressure effects was performed on a 16-cell stack by placing a thin pressure-sensitive film between GDL and bipolar plate. Clamping pressure was applied using various loads, durations, and two types of GDLs. The results from experimental testing show that pressure on the GDL is in the range of 0-2.5 MPa. When using rectangular cells, experimental results show nearly zero pressure in the center of each cell and the center cells of the stack, regardless of clamping method.
Yoon, Yohan,Mukherjee, Avik,Geornaras, Ifigenia,Belk, Keith E.,Scanga, John A.,Smith, Gary C.,Sofos, John N. Elsevier 2011 Food Control Vol.22 No.12
<P><B>Abstract</B></P><P>This study examined the effect of tenderizing/marinating and flavoring ingredients on thermal inactivation of <I>Escherichia coli</I> O157:H7 in a lean ground beef model system, simulating non-intact products. Ground beef (3% fat) was inoculated with <I>E</I>. <I>coli</I> O157:H7 (5 strains; 6–7 log CFU/g), followed by mixing with nothing (control) or solutions of water, a mixture of flavoring agents (FA), 0.23% calcium chloride (CC) + FA, CC + FA + 0.3% acetic acid (AA), 0.5% sodium chloride (NaCl) + 0.25% sodium tripolyphosphate (STP), NaCl + STP + FA, NaCl + STP + 1.8% potassium lactate (PL), NaCl + STP + PL + FA, NaCl + STP + PL + AA, and NaCl + STP + PL + AA + FA. Samples (30 g) were extruded into tubes, stored (4 °C) overnight, and cooked to 60 °C (rare) or 65 °C (medium-rare) in a water bath. Cooking weight losses, and fat and moisture contents, water activity, pH, and total bacterial and <I>E</I>. <I>coli</I> O157:H7 populations were determined after inoculation, after storage, and after heating. Reductions of the pathogen at 60 °C in acid (AA)-treated samples were higher than reductions obtained in samples not treated with acid. Surviving pathogen counts at 65 °C in NaCl and STP-treated samples with no acid were higher (<I>P</I> < 0.05) than those of samples of all other tested treatments; however, the counts decreased to 0.7–1.6 log CFU/g when AA was added. Overall, the results of the study indicate that tenderizing/flavoring ingredient formulations combined with 0.3% AA (i.e., CC + FA + AA, NaCl + STP + PL + AA, and NaCl + STP + PL + AA + FA) enhanced destruction of <I>E</I>. <I>coli</I> O157:H7 during cooking of a non-intact beef product.</P> <P><B>Highlights</B></P><P>► Thermal inactivation of <I>Escherichia coli</I> O157:H7 internalized in non-intact beef evaluated. ► Lean ground beef model system used to simulate non-intact products. ► Effect of beef tenderizing/marinating/flavoring ingredients on pathogen heat destruction determined. ► Pathogen reductions at 60 °C enhanced in acetic acid (AA)-treated beef. ► Addition of AA to salt + phosphate formulations enhanced pathogen destruction at 65 °C.</P>
서식지에 따른 사철나무 잎의 이온화 방사선 조사 후 항산화 활성 변화 차이
김진규 ( Jin Kyu Kim ),차민경 ( Min Kyoung Cha ),나디아빌헬모바 ( Nad`a Wilhelmova ),아니타무크헤르지 ( Anita Mukherjee ) 한국환경생물학회 2011 환경생물 : 환경생물학회지 Vol.29 No.4
As the plants grow in a fixed place, they can be a good indicator which reflects the level of environmental pollution. It is necessary for them to develop a strategy to cope with stress under unfavorable environmental conditions. In this study, spindle trees (Euonymus japonica) were collected from a clean area (Kijang) as well as a heavily polluted area (Onsan) to check applicability of irradiation combined with plant bioassay to environmental monitoring. The leaves were irradiated with 0, 50 and 100 Gy of gamma rays, and then evaluated for antioxidative capacity with 1,1 diphenyl 2 picrylhydrazyl (DPPH) assay and superoxide dismutase (SOD) analysis. The result shows that there was no significant changes in SOD and EDA (Electron Donationg Ability) in the samples collected from a polluted area. In the meanwhile, SOD increased in the samples from a clean area until 6 to 10 hours after irradiation, then it decreased gradually until 24 hours after irradiation. In conclusion, the plants in the polluted area have developed higher resistance to oxidative stress induced by ionizing radiation than those in the relatively clean area. Irradiation combined with plant bioassay on enzymatic activities and free radical scavenging capacity has proven to be a possible tool for biomonitoring the environmental pollution.
Yengkokpam, Sona,Sahu, N.P.,Pal, A.K.,Mukherjee, S.C.,Debnath, Dipesh Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.1
A Feeding trial was conducted to study the effects of three different sources and two levels of dietary gelatinized carbohydrate (GC) on nutrient utilization, growth, tissue composition and tissue enzyme activities of fingerlings of Catla catla (15.1-15.3 g). Six isocaloric (17.1-17.5 kJ/g) semi-purified diets were prepared either with rice, corn or tapioca at 40 or 50% GC each. The crude protein (CP) level used in the diet was 35% and 25% for 40% and 50% GC level, respectively to study the protein sparing effect of GC. The degree of gelatinization was higher for corn and tapioca than rice under similar cooking conditions. After a 60-d feeding trial, dry matter, carbohydrate, protein and lipid digestibility were higher in tapioca fed groups at both the levels of GC. However, the highest specific growth rate (SGR) and protein efficiency ratio (PER) were observed in the corn fed groups at 50% GC level indicating better utilization of nutrients from gelatinized corn. Feed conversion ratio (FCR) was almost similar in corn and tapioca fed groups between two levels of GC but in rice fed groups, FCR was lower in 40% GC than 50% GC level. The results indicated higher protein-sparing effect in corn and tapioca fed groups than rice fed groups. The order of gelatinized carbohydrate utilization in Catla catla fingerlings at 50% GC level was corn>tapioca>rice. At 40% GC level, corn and tapioca were comparable and more efficiently utilized than rice. In the corn fed groups, 50% GC was comparable with 40% GC level, whereas in rice and tapioca fed groups the 40% GC was better in terms of nutrient utilization. Liver glycogen content and hepatosomatic index were significantly (p<0.05) higher in those groups fed high GC (50%) irrespective of carbohydrate sources. Higher intestinal amylase and glucose-6-phosphate dehydrogenase activities were observed in higher GC fed groups than the lower GC groups. No mortality was found in any groups at any levels of GC.
Effect of Tilliacorine on Haematological and Biochemical Parameters
A. Roychowdhuri,J. Rajan Vedasiromoni,Malaya Gupta,S. K. Mitra,Biswapati Mukherjee,Arnab Khasnobis,Tapan Seal 한국생약학회 2000 Natural Product Sciences Vol.6 No.3
Tiliacora racemosa Colebr. belonging to the family Menispermaceae, is the biggest storehouse of diphenyl bisbenzylisoquinoline (DBBI) alkaloids. Exhaustive chemical processing of the root of T. racemosa by the application of modern separation techniques yielded a DBBI alkaloid which was identified as tiliacorine using sophisticated spectroscopic methods (UV, IR, ¹H-NMR, MS). Haematological study with tiliacorine proved that there was no abnormal haematological results in comparison with the normal values. Chronic toxicity study with tiliacorine revealed that the alkaloid is devoid of any hepatotoxic and nephrotoxic action.