이중고리 합성에 블록제로서 이용된 피란과 피리딘

El-Hashash, Maher.A.,El-Sawy, Abdallah.A.,Eissa, Abdelmonem.M.F. 대한화학회 2009 대한화학회지 Vol.53 No.3

현재 수행하는 작업은 피페리딘 또는 암모늄 아세테이트 존재하에서 malononitrile와 $\beta$- aroylacrylic acid 유도체의 DMF 용매조건에서 상호작용에 대한 연구이며, 형성된 화합물을 이용한 퓨즈 되고 단리된 이중고리화 시스템의 합성에 관한 것이다. $\beta$-aroylacrylic acid (3)이 DMF 용매와 피페리딘 촉매조건에malononitrile와 반응하여 4H-피란유도체(4)를 형성한다. 촉매를 암모늄아세테이트로 바꿈으로서 피리딘 유도체를 얻었다. 또한 N-말레암산 유도체 (19)와 (27)은 말레 무수물과 함께 (4)와 (5)의 반응을 경유하여 합성되었다. 마이클 첨가 반응에서 이용되는 메틸렌화합물에 관한 이 연구는 B-aroylacrylic acid의 경우와 유사하게 형성된 말레암산 유도체의 반응성에 대한 것이다. The present work is devoted to study the interaction of $\beta$-aroylacrylic acid derivative (3) with malononitrile in (DMF) in the presence of piperidine and/or ammonium acetate, then using the formed compounds as starting materials for synthesizing fused and isolated heterocyclic systems. It has been established that the $\beta$-aroylacrylic acid (3) reacts with malononitrile in (DMF) in the presence of piperidine as a catalyst with the formation of 4H-pyran derivative (4). By changing the catalyst into ammonium acetate, pyridine derivative (5) has been obtained. Also the N-maleamic acid derivatives (19) and (27) have been synthesized via the interaction of (4) and (5) with maleic anhydride. The purpose of this step is to study the behavior of the formed maleamic acid derivatives – as analogies of $\beta$-aroylacrylic acids – towards different active methylene compounds under Michael addition reaction.

Physiological and molecular study on the anti-obesity effects of pineapple (Ananas comosus) juice in male Wistar rat

Samir A. El-Shazly,Mohamed M. Ahmed,Mohammad S. AL-Harbi,Mohamed E. Alkafafy,Hanan B. El-Sawy,Sayed A. M. Amer 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.5

The present study was performed to assess antiobesity effects of raw pineapple juice in high fat diet (HFD)-induced fatness. Based on food type, rats were divided into normal diet and HFD groups. When animals of HFD group become obese, they were given pineapple juice along with either HFD or normal diet. Blood biochemistry, liver and muscle gene expressions were analyzed. HFD induced significant elevations in body weight, body mass index (BMI), body fat accumulation, liver fat deposition and blood lipids while juice restored these parameters near to their normal values. Juice significantly decreased serum insulin and leptin while adiponectin was increased. Juice administration downregulated the increment of FAS and SERBP-1c mRNA expression in liver and upregulated HSL and GLUT-2 expressions. The muscular lipolytic CPT-1 expression was upregulted by juice treatment. Pineapple juice, therefore, may possibly be used as anti-obesity candidate where it decreased lipogenesis and increased lipolysis.

Evaluation of Gamma-Ray Attenuation Parameters for Some Materials

Amal A. El- Sawy 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.11

In the present study, the linear attenuation coefficient and mass attenuation coefficient have been calculated at energy range of 0.8MeV, 1MeV, 3Mev, 5MeV and 7MeV. The mass attenuation Coefficient μm has been calculated analytically for Iron material Fe (ρ= 7.87 g/cm3) and developed material lead Pb (ρ= 11.3 g/cm3) at photon energies [0.8 MeV to 7 MeV] using X-Com computer code. The obtained results were compared with the calculated values. The linear attenuation Coefficient μ has been calculated, its variations with photon energy were plotting. The Comparison between two materials Iron and Lead were also studied. The obtained result shows that μ and μm depends on the photon energy, density of the materials and atomic number. From this study we notice that the values of μm and μ of Lead material is greater than Iron material and also the values are decreasing with increasing the photon energy. The half value layer (HVL) and tenth value layer (TVL) of two studied materials were calculated at photon energy range of 0.8 MeV, 1MeV, 5MeV and 7MeV. The relation between this equation Ln (Io/I) and the thickness of material were calculated, so the curves show that the relation of Ln (Io/I) of Iron and Lead materials is increasing with the increasing of material thickness and the relation gives the straight line, also the comparison of this relation for Lead material is higher than Iron material. This study can also be utilized to improve the effectiveness of radiation shielding by using the developed shielding material.

Synthesis and Antibacterial Activity of Azo-Sulfa-Based Disperse Dyes and Their Application in Polyester Printing

Hayam A. Abd El Salam,Mohamed S. Abdel‑Aziz,Eslam Reda El‑Sawy,Elkhabiry Shaban 한국섬유공학회 2023 Fibers and polymers Vol.24 No.8

For conjugating sulfa drug moieties with Schiff’s bases scaffold in the same build through an azo linker to take advantage of the bioactive feature of both motifs, we designed and synthesized a series of bioactive disperse dyes. The target disperse dyes, methyl 2-(E-2-hydroxy-5-((E)-(4-sulfa-derivative) diazenyl)benzylidene) hydrazine-1-carbodithioates 4a–e have been synthesized via the acidic reaction of azo dyes 3a–e with methyl hydrazine carbodithioate. Structures of the synthesized dyes were clarified based on their spectral and elemental analyses. The effectiveness of the dyes was initially tested as an antibacterial toward Staphylococcus aureus ATCC 6538-P and Escherichia coli ATCC 25933. Dyes that were proven to be effective against bacteria have been used as disperse dyes to print polyester fabrics. The color properties of the dyes and their fastness properties counting washing, perspiration, light, rubbing, and sublimation fastness were also examined. The printed polyester fabrics were evaluated for their antibacterial activity via colony-forming unit (CFU) technique. Fabric samples treated with 4c, 4d, and 4b had promising anti-Gram-positive activities against S. aureus. Whereas 4c-, 4d-, and 4b-treated fabrics exhibited moderate anti-Gram-negative activities against the test bacterium E. coli.

Digital Transformation to Real-Time Enterprise to Sustain Competitive Advantage in the Digitized World: The Role of Business Intelligence and Communication Systems

YoungKi Park(박영기),Omar A. El Sawy,Taeho Hong(홍태호) 한국경영학회 2020 Korea Business Review Vol.24 No.신년 특별호

본 연구에서는 기업이 실시간 기업(Real-Time Enterprise: RTE)로의 디지털 트랜스포메이션을 통해 디지털 비즈니스 세상에서 기회와 위협으로 나타나는 중요한 비즈니스 이벤트를 성공적으로 감지하고 관리할 수 있다는 것을 설명하는데 있다. 본 연구에서는 RTE 능력을 중요한 비즈니스 이벤트에 시기적절하게 감지하고 반응할 수 있는 조직의 능력으로 정의한다. 더 나아가서, 센스메이킹과 실행 능력을 RTE 능력의 두 축으로 설정하고, 비즈니스 인텔리전스와 통신지원을 디지털 트렌스포메이션을 통한 RTE로 도달하는 두 개의 중요한 기술로 정의한다. 다양한 산업에서 총 96개 기업을 대상으로 191개의 설문조사 자료를 사용하여 비즈니스 인텔리전스와 통신지원기술이 RTE 능력과 기업 성과를 달성하는데 있어서 각기 다르게 역할을 하고 있음을 실증분석을 통해 제시하였다. 정보기술은 빠르게 변화하는 환경에서 RTE 능력을 확장하여 간접적으로 기업이 경쟁우위를 달성할 수 있게 할 수 있음을 본 연구에서 제시하였다. 느린 환경에서는 RTE능력이 기업 성과를 높이지 않는 것으로 분석되었으며, 재설정된 자원과 구조에 대한 잦은 대처는 오히려 경쟁우위를 감퇴시기는 것으로 분석되었다. This study aims to explain digital transformation of firms to real-time enterprises (RTE) that can successfully sense and manage important business events that appear as opportunities and threats in the digitized business world. We define RTE capabilities as the organizational ability to sense and act to important business events in a timely manner. Furthermore, we define sensemaking and acting capability as two dimensions of RTE capabilities and business intelligence and communication support as two key information technologies for digital transformation into RTE. Using 191 survey responses from 96 firms in diverse industries, we find that the different roles of BI and communication support technologies in achieving high RTE capabilities and firm performance across different environmental velocities. IT enables firms to achieve competitive advantage indirectly by enhancing RTE capabilities in fast environments. In slow environments, RTE capabilities appear not to enhance performance, but instead frequent actions to reconfigure resources and structures seem to deteriorate competitive advantage.

Determining the Efficient Solutions for Bicriteria Programming Problems with Random Variables in Both the Objective Functions and the Constraints

( B. I. Bayoumi ),( A. A. El Sawy ),( N. L. Baseley ),( I. K. Yousef ),( A. M. Widyan ) 한국산업응용수학회(구 한국산업정보응용수학회) 2005 한국산업정보응용수학회 Vol.9 No.1

Determining the Efficient Solutions for Bicriteria Programming Problems with Random Variables in Both the Objective Functions and the Constraints

B. I. Bayoumi,A. A. El-Sawy,N. L. Baseley,I. K.Yousef,A.M. Widyan 한국산업응용수학회 2005 Journal of the Korean Society for Industrial and A Vol.9 No.1

This paper suggests an efficient approach for stochastic bicriteria programming problem (SBCPP) with random variables in both the objective functions and in the right-hand side of the constraints. The suggested approach uses the statistical inference through two different techniques: In one of them , the SBCPP is transformed into an equivalent deterministic bicriteria programming problem (DBCPP), then the nonnegative weighted sum approach will be used to transform the bicriteria programming problem into a single objective programming problem, and the other technique, the nonnegative weighted sum approach is used to transform the SBCPP to an equivalent stochastic single objective programming problem, then apply the same procedure to convert stochastic single objective programming problem into its equivalent deterministic single objective programming problem (DSOPP). In both techniques the resulting problem can be solved as a nonlinear programming problem to get the efficient solutions. Finally, a comparison between the two different techniques is discussed, and illustrated example is given to demonstrate the actual application of these techniques.

Magnetic Monopole Search with the Full MoEDAL Trapping Detector in 13 TeV pp Collisions Interpreted in Photon-Fusion and Drell-Yan Production

Acharya, B.,Alexandre, J.,Baines, S.,Benes, P.,Bergmann, B.,Bernabé,u, J.,Bevan, A.,Branzas, H.,Campbell, M.,Cecchini, S.,Cho, Y. M.,de Montigny, M.,De Roeck, A.,Ellis, J. R.,El Sawy, M.,Fairbai American Physical Society 2019 Physical Review Letters Vol.123 No.2