Muhammad Abduh와 Taha Hussein의 敎育 思想

El-Sawy, Muhammad 西原大學校 敎育硏究所 1988 師道文化 Vol.5 No.-

이중고리 합성에 블록제로서 이용된 피란과 피리딘

El-Hashash, Maher.A.,El-Sawy, Abdallah.A.,Eissa, Abdelmonem.M.F. 대한화학회 2009 대한화학회지 Vol.53 No.3

현재 수행하는 작업은 피페리딘 또는 암모늄 아세테이트 존재하에서 malononitrile와 $\beta$- aroylacrylic acid 유도체의 DMF 용매조건에서 상호작용에 대한 연구이며, 형성된 화합물을 이용한 퓨즈 되고 단리된 이중고리화 시스템의 합성에 관한 것이다. $\beta$-aroylacrylic acid (3)이 DMF 용매와 피페리딘 촉매조건에malononitrile와 반응하여 4H-피란유도체(4)를 형성한다. 촉매를 암모늄아세테이트로 바꿈으로서 피리딘 유도체를 얻었다. 또한 N-말레암산 유도체 (19)와 (27)은 말레 무수물과 함께 (4)와 (5)의 반응을 경유하여 합성되었다. 마이클 첨가 반응에서 이용되는 메틸렌화합물에 관한 이 연구는 B-aroylacrylic acid의 경우와 유사하게 형성된 말레암산 유도체의 반응성에 대한 것이다. The present work is devoted to study the interaction of $\beta$-aroylacrylic acid derivative (3) with malononitrile in (DMF) in the presence of piperidine and/or ammonium acetate, then using the formed compounds as starting materials for synthesizing fused and isolated heterocyclic systems. It has been established that the $\beta$-aroylacrylic acid (3) reacts with malononitrile in (DMF) in the presence of piperidine as a catalyst with the formation of 4H-pyran derivative (4). By changing the catalyst into ammonium acetate, pyridine derivative (5) has been obtained. Also the N-maleamic acid derivatives (19) and (27) have been synthesized via the interaction of (4) and (5) with maleic anhydride. The purpose of this step is to study the behavior of the formed maleamic acid derivatives – as analogies of $\beta$-aroylacrylic acids – towards different active methylene compounds under Michael addition reaction.

Physiological and molecular study on the anti-obesity effects of pineapple (Ananas comosus) juice in male Wistar rat

Samir A. El-Shazly,Mohamed M. Ahmed,Mohammad S. AL-Harbi,Mohamed E. Alkafafy,Hanan B. El-Sawy,Sayed A. M. Amer 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.5

The present study was performed to assess antiobesity effects of raw pineapple juice in high fat diet (HFD)-induced fatness. Based on food type, rats were divided into normal diet and HFD groups. When animals of HFD group become obese, they were given pineapple juice along with either HFD or normal diet. Blood biochemistry, liver and muscle gene expressions were analyzed. HFD induced significant elevations in body weight, body mass index (BMI), body fat accumulation, liver fat deposition and blood lipids while juice restored these parameters near to their normal values. Juice significantly decreased serum insulin and leptin while adiponectin was increased. Juice administration downregulated the increment of FAS and SERBP-1c mRNA expression in liver and upregulated HSL and GLUT-2 expressions. The muscular lipolytic CPT-1 expression was upregulted by juice treatment. Pineapple juice, therefore, may possibly be used as anti-obesity candidate where it decreased lipogenesis and increased lipolysis.

Evaluation of Gamma-Ray Attenuation Parameters for Some Materials

Amal A. El- Sawy 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.11

In the present study, the linear attenuation coefficient and mass attenuation coefficient have been calculated at energy range of 0.8MeV, 1MeV, 3Mev, 5MeV and 7MeV. The mass attenuation Coefficient μm has been calculated analytically for Iron material Fe (ρ= 7.87 g/cm3) and developed material lead Pb (ρ= 11.3 g/cm3) at photon energies [0.8 MeV to 7 MeV] using X-Com computer code. The obtained results were compared with the calculated values. The linear attenuation Coefficient μ has been calculated, its variations with photon energy were plotting. The Comparison between two materials Iron and Lead were also studied. The obtained result shows that μ and μm depends on the photon energy, density of the materials and atomic number. From this study we notice that the values of μm and μ of Lead material is greater than Iron material and also the values are decreasing with increasing the photon energy. The half value layer (HVL) and tenth value layer (TVL) of two studied materials were calculated at photon energy range of 0.8 MeV, 1MeV, 5MeV and 7MeV. The relation between this equation Ln (Io/I) and the thickness of material were calculated, so the curves show that the relation of Ln (Io/I) of Iron and Lead materials is increasing with the increasing of material thickness and the relation gives the straight line, also the comparison of this relation for Lead material is higher than Iron material. This study can also be utilized to improve the effectiveness of radiation shielding by using the developed shielding material.

Morphometric analysis of vastus medialis oblique muscle and its influence on anterior knee pain

Marwa M El Sawy,Dalia M E EL Mikkawy,Sayed M El-Sayed,Ahmed M. Desouky 대한해부학회 2021 Anatomy & Cell Biology Vol.54 No.1

Healthy knees require full range squatting movements. Vastus medialis (VM) muscle regulates and adjusts the extensor apparatus that inf luences the patellofemoral function. This work was designed to investigate the anatomy and morphometry of vastus medialis oblique (VMO) muscle by widely used imaging techniques and investigate how VMO muscle participates in anterior knee pain. Ten dissected cadaveric specimens were examined, focusing on fiber orientations, origin, insertions and nerve supply of VMO muscle. Magnetic resonance imaging and ultrasound of VMO muscle were recorded. Anatomical cross-sectional areas of VMO muscle were determined in painless and painful knees and statistically analyzed. In cadaveric specimens, there was distinct separation between VM longus and VMO (change in fiber angle or fibro-fascial plane). VMO inserted directly into the medial proximal margin of the patella, capsule of the knee joint and continuous with the patellar tendon. Separate branch of femoral nerve run along the anteromedial border of the muscle. Anatomical cross-sectional area was significantly decreased in painful knee by –17.2%±11.0% at lower end of shaft of femur, –21.1%±6.0% at upper border of patella, –36.7%±11.0% at mid-patellar level. VMO is distinct muscle within quadriceps femoris group. VMO muscle would track the patella medially and participate in last phase of knee extension. Assessment of the VMO muscle anatomical cross-sectional area by ultrasonography may constitute promising and reliable tool to evaluate patellofemoral pain syndrome staging.

Synthesis and Antibacterial Activity of Azo-Sulfa-Based Disperse Dyes and Their Application in Polyester Printing

Hayam A. Abd El Salam,Mohamed S. Abdel‑Aziz,Eslam Reda El‑Sawy,Elkhabiry Shaban 한국섬유공학회 2023 Fibers and polymers Vol.24 No.8

For conjugating sulfa drug moieties with Schiff’s bases scaffold in the same build through an azo linker to take advantage of the bioactive feature of both motifs, we designed and synthesized a series of bioactive disperse dyes. The target disperse dyes, methyl 2-(E-2-hydroxy-5-((E)-(4-sulfa-derivative) diazenyl)benzylidene) hydrazine-1-carbodithioates 4a–e have been synthesized via the acidic reaction of azo dyes 3a–e with methyl hydrazine carbodithioate. Structures of the synthesized dyes were clarified based on their spectral and elemental analyses. The effectiveness of the dyes was initially tested as an antibacterial toward Staphylococcus aureus ATCC 6538-P and Escherichia coli ATCC 25933. Dyes that were proven to be effective against bacteria have been used as disperse dyes to print polyester fabrics. The color properties of the dyes and their fastness properties counting washing, perspiration, light, rubbing, and sublimation fastness were also examined. The printed polyester fabrics were evaluated for their antibacterial activity via colony-forming unit (CFU) technique. Fabric samples treated with 4c, 4d, and 4b had promising anti-Gram-positive activities against S. aureus. Whereas 4c-, 4d-, and 4b-treated fabrics exhibited moderate anti-Gram-negative activities against the test bacterium E. coli.

A modified trans-anconeus approach to facilitate fixation of a posterior radial head fracture: a cadaveric feasibility study

Ahmed Mohamed Desouky(Ahmed Mohamed Desouky ),Ahmed Naeem Atiyya(Ahmed Naeem Atiyya ),Mohamed Elbishbishi(Mohamed Elbishbishi ),Marwa Mohamed El Sawy(Marwa Mohamed El Sawy ) 대한해부학회 2023 Anatomy & Cell Biology Vol.56 No.1

Fixation of radial head fracture with minimally invasive posterior approach remains a significant challenge. The aim of this study was to determine the feasibility of trans-anconeus posterior elbow approach and to observe lateral ulnar collateral ligament (LUCL) in extended elbows. This cadaveric study was performed in twenty upper limbs of fresh fixed adult male cadavers. An oblique incision was made in the middle segment of anconeus until the lateral ligament complex and the joint capsule had been revealed. A deep dissection was explored to observe the anatomical relationship of the LUCL to the anconeus. Measurements of the LUCL were recorded while the elbow was fully extended. The mean distance between the edge of the radial head and the proximal insertion of the LUCL was 13.3 mm (11.5–16.2 mm); the mean distance between the edge of the radial head and the distal insertion of the LUCL was 20.9 mm (19.2–23.4 mm); the distance between the edge of the radial head and the distal edge of the annular ligament was 11.2 mm (8.22–11.7 mm). By estimate correlation of the previous measurements, the direct and accessible way to expose the posterolateral articular capsule of the elbow joint was through a window in medial 2/3 of the middle segment of anconeus muscle. These trans-anconeus approach is useful. It provides good visualization, facilitates applying the implants, and lessens the risk of radial nerve injury. Awareness of the anatomy is mandatory to avoid injury of LUCL.

Neuroprotective effect of Salvia splendens extract and its constituents against AlCl3-induced Alzheimer’s disease in rats

El-Sawi Salma Ahmed,Shahira Mohamed Ezzat,Hanan Farouk Aly,Rana Merghany Merghany,Meselhy Ragab Meselhy 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.3

Salvia splendens is a species of the genus Salvia that is known for its neuro-therapeutic properties. The present study aimed to investigate the effect of two fractions from the methanolic extract of the aerial parts of S. splendens cultivated in Egypt, the petroleum ether-soluble (PES) and n-butanol-soluble (BS) fractions, against AlCl3- induced Alzheimer’s disease (AD) in rats. Rats treated with AlCl3 (100 mg/kg b.wt. p.o.) for 4 weeks developed behavioral, biochemical and histological changes similar to that of AD. Behavioral deficits were assessed by T-maze test and percentage changes in oxidative stress and AD markers in brain. Extent of DNA damage and histopathological changes were also evaluated. Results revealed that both fractions; PES and BS (at dose of 500 mg/kg b.wt), significantly attenuated AlCl3- induced behavioral impairment in rats. This effect was accompanied by acetylcholinesterase (AChE) activity inhibition (53.18% and 68.66%, respectively), and Aβ deposition reduction (33.3% and 34.3%, respectively). Both fractions markedly decreased oxidative stress markers level (lipid peroxide, protein carbonyl, reduced glutathione and nitric oxide), and inhibited catalase and caspase-3 activities. Also, the content of noradrenaline, adrenaline, 5-HT and dopamine were significantly increased. The fractions preserved the histo-architecture pattern of the hippocampus and cortex from the AlCl3- induced damage. Bioactivity-guided fractionation led to the isolation of two sterols; β-sitosterol and β-sitosterolpalmitate from PES fraction, and 6 phenolic compounds (acacetin, chrysoeriol, apigenin, luteolin, rosmarinic acid and caffeic acid) from BS fraction. Rosmarinic acid and caffeic acid significantly inhibited AChE in vitro ( IC50 values of 0.398 mg/mL and 0.327 mg/mL, respectively) compared to physostigmine ( IC50 0.227 mg/ mL). The BS fraction is standardized (HPLC–DAD) to contain not less than 0.0254% (w/w)of rosmarinic acid and 0.0129% (w/w) of caffeic acid. These findings suggest that S. splendens is beneficial in attenuating AlCl3- induced neurotoxicity in rats.

Year-round Monitoring of Verotoxin-producing Escherichia coli from Feces of Dairy Cattle

Kobayashi, Y.,El-Sawy, H.B.I. Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.5

A PCR-aided monitoring of verotoxin-producing Escherichia coli (VTEC) was performed over the period of 12 months by using fresh feces collected monthly from 5 dairy cows that had been identified as VTEC carriers. The PCR products were confirmed to be verotoxin genes by Southern hybridization using a gene fragment of verotoxin 2 as a probe. Although seasonal variation of VTEC shedding seemed to depend on each cow, several factors may have influenced the frequency of detection. Shedding of VTEC tended to be reduced during grazing from the middle of May up to the beginning of October. Only one cow was positive for VTEC in August. Dry-off was also suggested to have a depressive effect on VTEC shedding, i.e. 3 of 4 dry cows showed no shedding of VTEC. Contrary to these factors, winter or indoor rearing tended to increase VTEC with only 5/24 samples being negative during the period from November to April. Total VFA concentration was higher (p<0.05) in VTEC-positive feces than in VTEC-negative feces, while fecal pH and VFA proportions were not different. Partial sequences of verotoxin genes from feces of 4 VTEC-positive cows were nearly identical (99-100%), suggesting that gut bacteria sharing the same gene were distributed among the cows. The present results indicate that grazing and dry-off could be factors which reduce VTEC shedding, while winter/indoor rearing may be a factor which increases the shedding, possibly through on-farm interactions.

Determining the Efficient Solutions for Bicriteria Programming Problems with Random Variables in Both the Objective Functions and the Constraints

B. I. Bayoumi,A. A. El-Sawy,N. L. Baseley,I. K.Yousef,A.M. Widyan 한국산업응용수학회 2005 Journal of the Korean Society for Industrial and A Vol.9 No.1

This paper suggests an efficient approach for stochastic bicriteria programming problem (SBCPP) with random variables in both the objective functions and in the right-hand side of the constraints. The suggested approach uses the statistical inference through two different techniques: In one of them , the SBCPP is transformed into an equivalent deterministic bicriteria programming problem (DBCPP), then the nonnegative weighted sum approach will be used to transform the bicriteria programming problem into a single objective programming problem, and the other technique, the nonnegative weighted sum approach is used to transform the SBCPP to an equivalent stochastic single objective programming problem, then apply the same procedure to convert stochastic single objective programming problem into its equivalent deterministic single objective programming problem (DSOPP). In both techniques the resulting problem can be solved as a nonlinear programming problem to get the efficient solutions. Finally, a comparison between the two different techniques is discussed, and illustrated example is given to demonstrate the actual application of these techniques.