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갱년기 증상을 호소하는 여성들의 적외선 체열 영상 유형에 대한 연구
허자경,황덕상,이창훈,김용석,이경섭,Heo, Ja-Kyung,Hwang, Deok-Sang,Lee, Chang-Hoon,Kim, Yong-Suk,Lee, Kyung-Sub 대한한방체열의학회 2009 대한한방체열의학회지 Vol.7 No.1
Purpose : Among many symptoms that the climacteric patients complain of, the major symptom is heat and cold sensation of body in various pattern. So, we are intended to study patterns of climacteric patients by using D.I.T.I. Methods : We studied 55 patients visiting OO Oriental Hospital from 1st January 2008 to 31th December 2008. The patients were distributed one of patterns by inspecting D.I.T.I. And we investigated the temperature of the region of body in 5 groups. Results : There are five groups in D.I.T.I. Those are heat sensation of face pattern, heat sensation of chest pattern, cold sensation of hand & foot pattern, heat sensation of hand pattern and cold sensation of lower abdomen pattern. 22 subjects are in heat sensation of face group. 12 subjects are in heat sensation of chest group. 12 subjects are in heat sensation of hand group. 6 subjects are in cold sensation of lower abdomen group. 3 subjects are in cold sensation of hand & foot group. Conclusion : 5 patterns of D.I.T.I is showed in climacteric patients. To help oriental medical diagnosis, further studies are needed.
한방 비만 치료 후 간기능 개선을 보인 비알코올성 지방간 환자 1례 보고
허자경 ( Ja Kyung Heo ),황덕상 ( Deok Sang Hwang ),이창훈 ( Chang Hoon Lee ),이경섭 ( Kyung Sub Lee ) 한방비만학회 2007 한방비만학회지 Vol.7 No.2
The purpose of this study was to investigate the clinical effect of oriental medical obesity therapy on obese patient with non-alcoholic fatty liver disease. We supposed to treat patient 21 years old that had non-alcoholic fatty liver with oriental medical obesity therapy. Methods The patient was treated from the 19th of July to the 22th of August for obesity treatment. And the patient had intensive care through admission treatment from the 19th of July to the 30th of July. Herbal medicine, low calorie and low cholesterol diet, electrolipolysis, auricular acupuncture, aerobic exercise was done during the treatment period. Results His body weight decreased from 107.10㎏ to 98.85㎏. The BMI decreased from 36.2㎏/㎡ to 34.5㎏/㎡. Abdominal visceral fat tissue decreased from 190.80㎠ to 145.05㎠. AST was decreased from 113 to 45. ALT was decreased from 145 to 40. r-GT was decreased from 123 to 51. Oriental obesity therapy could be effective to treat obese patient with non-alcoholic fatty liver disease. Conclusions The obese patient with non-alcoholic fatty liver disease had improved liver function after oriental obesity treatment.
DITI를 이용한 대하증을 호소하는 환자의 복부 온도 연구
허자경,정재혁,조정훈,이진무,이창훈,장준복,이경섭,Heo, Ja-Kyung,Jeong, Jae-Hyuk,Cho, Jung-Hoon,Lee, Jin-Moo,Lee, Chang-Hoon,Jang, Jun-Bock,Lee, Kyung-Sub 대한한방체열의학회 2008 대한한방체열의학회지 Vol.6 No.1
Purpose: We intended to researched the relations between abdominal temperature and leukorrhea. Methods: We selected the 26 leukorrhea patients and 17 control group. We measured 4 points abdominal temperature (Chung-wan(CV12), Kwan-won(CV4), Gui-rae(ST29)) by DITI. We checked the difference of temperature between CV12, CV4, ST29 of leukorrhea group and control group. And we checked the difference of temperature between CV12 and CV4 / Lt. ST29 and Rt. ST29 / CV12 and Lt. ST29 / CV12 and Rt. ST29 / CV4 and Lt. ST29 / CV4 and Rt. ST29. For statistics, we used Mann-Whitney test, SPSS 12.0 for windows. Results: The difference of temperature between CV12, CV4 and ST29 which are abdomen shows statistically insignificant result in this study. But, the difference of temperature between (${\Delta}T$) CV4 and Rt. ST29 which are abdomen shows statistically significant result. Conclusion: The leukorrhea patients show higher temperature CV12, CV4 and ST29 than control group. In lower abdomen, the temperature between leukorrhea and control group shows little difference.
하고초(夏枯草)에서 추출한 Ursolic acid의파골세포 분화 억제 효과
허자경 ( Ja Kyung Heo ),황덕상 ( Deok Sang Hwang ),이진무 ( Jin Moo Lee ),이창훈 ( Chang Hoon Lee ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ) 대한한방부인과학회 2014 大韓韓方婦人科學會誌 Vol.27 No.2
This study was conducted to evaluate the inhibitory effect of ursolicacid from Prunella vulgaris on osteoclast differentiation. Methods: MTT-assay was performed to estimate cytotoxicity of ursolic acidfrom Prunella vulgaris in BMMs stimulated with M-CSF. TRAP staining, TRAPactivity and Real-time PCR were performed to know the inhibitory effect onosteoclast differentiation. Actin ring formation were analysed to observe the effectof ursolic acid from Prunella vulgaris. Results: Ursolic acid from Prunella vulgaris has no cytotoxicity at the concentrationof 1 μg/ml or lower. Ursolic acid decreased the number of TRAP positive cells and the expression of NFATc1 gene, c-Fos gene, TRAP and OSCAR in BMMs stimulatedwith RANKL. Ursolic acid restrained the formation of actin ring. Ursolic acidinhibited NF-κB activity by inducing degradation of p-IkBa.Conclusions: Ursolic acid from Prunella vulgaris has the inhibitory effect ofosteoclast differentiation and bone resorption. Futher studies are needed to treatosteoporosis by usolic acid from Prunella vulgaris.