http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
탁상도,문선미,황대용,장웅규,이수용 대한대장항문학회 2004 Annals of Coloproctolgy Vol.20 No.5
Purpose: Since the first case of bone metastasis of a rectal carcinoma was reported by Curling in 1870, bone metastasis in primary colorectal cancer has remained uncommon event. The aim of our study was to gain insight into the clinical characteristics of bone metastasis of colorectal cancer. Methods: This is a 10-year retrospective study that covers patients with bone metastasis of colorectal cancer in the Department of Surgery, Korea Cancer Center Hospital, from Jan. 1993. Results: In a total of 1461 cases of primary colorectal cancer treated in the same period, the clinical analysis was possible in 1356 cases. Of these, 53 cases showed bone metastasis. The incidence of bone metastasis was 3.9. Thirteen cases (25%) had bone metastasis only whereas 40 cases (75%) had bone metastasis combined with metastases of other organs. The most frequent site of bone metastasis was the vertebral bone (38, 71.7%), especially the thoracic spine (21, 39.6%). The median survival after onset of bone metastasis was 4.4 months, including 9.8 months in the bone-metastasis-only group and 3.5 months in bone metastasis with other-sitemetastasis group. However, there was no significant difference in survival rate from the onset of bone metastasis between the two groups (P=0.3876). Conclusions: If the colorectal cancer patient has complaint of bony pain, bone metastasis should be considered even though it is a rare event. However, most cases of bone metastasis occur with metastases of other organs. Management is often limited to simple procedures intended to relieve pain in the terminal phase of the disease.
오창호,탁상용,이지호,Lanhua Piao 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.8
Enynals bearing an olefinic pendant were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic Pt-carbene complexes which would undergo insertion into a C-H bond of the β-position to afford the fused cyclopropane intermediates. Their tandem rearrangement afforded diverse types of spiranes depending on the tethered alkenes of the enynals.