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UV/GAC 흡착산화 공법을 이용한 원자력 발전소 2차 계통 냉각수로부터 발생하는 에탄올 아민 함유 폐수처리
최민준 ( Min Jun Choi ),김한수 ( Hansoo Kim ) 한국공업화학회 2017 공업화학 Vol.28 No.3
원자력발전소 2차 계통수에 사용되는 에탄올아민이 포함된 오염수는 복수탈염설비의 이온교환수지에서 포집된다. 이온교환수지의 재생과정에서 에탄올아민과 다량의 이온성 물질이 포함된 강산성 폐수가 발생된다. 본 연구는 이온교환 수지에서 발생하는 폐수를 처리하기 위해서 자외선 산화방법을 적용하였다. 산화방법은 흡착제를 함께 사용한 자외선 산화와 흡착제를 적용하지 않고 자외선 산화만 적용할 수 있는 장치를 개발하여 자외선 산화방법에서 흡착제가 폐수처리 성능에 미치는 영향을 파악하였다. 연구 결과는 입상활성탄을 흡착제로 적용한 UV/GAC산화공정은 pH 12.8에서 COD 제거 효율은 71.3%로 나타났다. 동일한 pH 조건에서 흡착제를 적용하지 않은 UV 산화공정보다 COD 제거 효율이 21.8% 높게 나타났다. T-N의 제거는 pH 12.8일 때 88.6%로 흡착제를 적용하지 않은 UV산화공정보다 18.0% 높게 나타났다. 이와 같은 결과는 입상활성탄이 에탄올아민을 고정시켜서, UV 램프에 의한 산화공정의 효율을 높이는 것으로 여겨진다. 따라서 UV/GAC 흡착산화공정이 에탄올아민 함유 폐수의 처리에 더 효율적이다. Wastewater including ethanolamine used in the second generation of nuclear power plants is filtered out in the ion exchange resin of the condensate polishing plant. In the regeneration process of ion exchange resin, a strong acidic wastewater containing ethanolamine and a lager amount of ionic substances are released. In this study, the process involving UV oxidation part with or without absorbents was developed for treating wastewater released from the ionic exchange resin. The effect of adsorbents on the wastewater treatment was investigated by using UV oxidation system developed by us. As a result, the COD removal efficiency of UV/GAC process with the granular activated carbon (GAC) as an adsorbent was 71.3% at pH 12.8. The removal efficiency was 21.8% higher than that of the wastewater treated using UV oxidation process without any adsorbents at the same condition. The removal of T-N was 88.6% at pH 12.8 when using UV oxidation with the GAC absorbent, which was 18.0% higher than that of using the UV oxidation process without any absorbents. It is thought that ethanolamine adsorbed on the absorbent improved the efficiency of UV oxidation process. Therefore, the UV/GAC adsorption oxidation process can be more effective in treating wastewater containing ethanolamine than that of using the process without any absorbents.
유럽인 자료로 산출된 양극성 장애 다유전자 위험 점수의 한국인 양극성 장애 환자에의 적용
최민준(Min Jun Choi),이동빈(Dong Bin Lee),조윤지(Yunji Cho),조은영(Eun Young Cho),홍경수(Kyung Sue Hong),백지현(Ji Hyun Baek) 대한신경정신의학회 2021 신경정신의학 Vol.60 No.3
Objectives This study examined whether the polygenic risk score (PRS) calculated from the most recent genome-wide association study for bipolar disorder (BD) of European ancestry patients is significantly associated with BD diagnosis in the Korean population. Methods The study included 417 Korean patients with BD and 497 healthy controls. Genotyping was performed using the Korean Biobank Array. Summary statistics of the European samples from the Psychiatric Genomic Consortium were used as base data to generate the PRS for each individual. The program PRSice-2 was used to calculate the PRS. Logistic regression was conducted to determine the association between BD diagnosis and PRS for BD after adjusting for age and sex. Results PRS for BD was significantly higher in patients diagnosed with BD compared to healthy controls. The PRS at the p-value threshold of 0.01 best explained the variance of BD after adjusting for age and sex (R2=0.0061, p=0.039). Subgroup analyses were performed for bipolar I and II subgroups. In bipolar I patients, the PRS at the p-value threshold of 0.01 best explained the diagnosis (R2=0.0165, p=0.0055), whereas no significant result was found for bipolar II patients. Conclusion PRS for BD calculated for the Korean sample showed a significant association with the BD diagnosis. This result suggests an overlapping genetic risk for BD between the European and Korean populations.