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증식성 근막염의 세침흡인 세포학적 소견 - 1 예 보고-
조향정,한원철,박원철,윤기중,Jo, Hyang-Jeong,Han, Won-Cheol,Park, Won-Cheol,Yun, Ki-Jung 대한세포병리학회 2002 대한세포병리학회지 Vol.13 No.1
Fine needle aspiration cytology (FNAC) is an easy convenient non-invasive method in the diagnosis of superficial palpable masses. The cytologic findings by FNAC of reactive and neoplastic lesions in various organs including breast, lymph node, thyroid, salivary gland, etc., have been described, but, those of soft tissue lesions including proliferative fasciitis are relatively rare to find. We recently experienced a case of FNAC of proliferative fasciitis in the left back of a 72-year-old male. The FNAC smears were scant in cellularity and contained large cells with abundant basophilic cytoplasm, one to two nuclei lying at the periphery, and prominent nucleoli that resemble ganglion cells.
조향정,오정택,김강득,김헌수,Jo, Hyang-Jeong,Oh, Jung-Taek,Kim, Gang-Deuk,Kim, Hun-Soo 대한세포병리학회 2007 대한세포병리학회지 Vol.18 No.2
A case of Burkitt lymphoma diagnosed through fine needle aspiration cytology is described, A 66-year-old man presented with lymphadenopathy on the right cervical neck and axillary area. An ultrasonogram and CT scan for the cervical neck showed a multiple variable sized lymphadenopathy with pericapsular invasion and necrotic foci, Fine needle aspiration cytology (FNAC) of the cervical lymph nodes revealed very cellular and necrotic smears consisting of diffusely scattered intermediate monotonous round cells, tingible body macrophages and many mitotic figures. Histological features of the excised lymph nodes showed the classic morphological features of Burkitt lymphoma. Recognition of the characteristic cytological features can suggest the possibility of Burkitt lymphoma.
조향정 ( Hyang Jeong Jo ),김홍곤 ( Heung Gon Kim ),문형배 ( Hyung Bae Moon ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.3
Angiomyofibroblastoma of the vulva is a recently described mesenchymal tumor. It can be distinguished from an aggressive angiomyxoma by its circumscribed borders, higher cellularity, more numerous blood vessels, the frequent presence of stromal cells, min
악하선의 석회화를 동반한 타액선 관암종의 세침흡인 세포학적 소견 - 1예 보고 -
윤기중,한원철,조향정,이광만,Yun, Ki-Jung,Han, Weon-Cheol,Jo, Hyang-Jeong,Lee, Kwang-Man 대한세포병리학회 2001 대한세포병리학회지 Vol.12 No.1
Salivary duct carcinoma is an uncommon aggressive malignant epithelial neoplasm with similarity to intraductal carcinoma of the breast. This neoplasm occurs most often in the parotid gland of middle-aged and older males. About 7% of reported tumors occured in the submandibular gland. The report of salivary duct carcinoma with calcification is rare. We report a case of salivary duct carcinoma with calcification in the submandibular gland. The patient was a 73-year-old male with a mass of the right submandibular gland for 1 year. On the fine needle aspiration cytology, the aspirate showed scant cellularity, small clusters of tumor cells, and scattered small calcifications. Nuclei of the tumor cells showed mild pleomorphism and round to oval in shape, and cytoplasm was abundant and finely granular. Nucleoli were indistinct and necrosis was not noted. There were no cribriform or papillary arrangements of tumor cells. Cytologlc findings of salivary duct carcinoma are variable depending on histologic findings, and calcifications could be an additional cytologic findings.
족무지 근위지절 골연골종과 동반한 무지 강직증 (증례보고)
채수욱,김영진,조향정,최덕화,차명수,Chae, Soo Uk,Kim, Yeung Jin,Jo, Hyang Jeong,Choi, Deok Hwa,Cha, Myoung Soo 대한족부족관절학회 2013 대한족부족관절학회지 Vol.17 No.1
Small osteophytes are frequently encountered in the foot and ankle, and not to be confused with true osteochondromas, which are relatively uncommon in this region. Osteochondromas are the most common benign osseous neoplasm, occurs in the metaphysis of the long bone. It is rarely found in bones of the foot. Treatment of the osteochondroma is usually conservative, unless symptoms usually pain, are progressive rapid growth, and malignant transformation is suspected. We experienced a rare case of hallux rigidus with osteochondroma of the hallucal proximal phalanx which cause pain and corn of the plantar.
영양분이 결핍된 H460 세포주에서 자가포식이 세포사멸에 미치는 영향
장혜연 ( Hye Yeon Jang ),조향정 ( Hyang Jeong Jo ),황기은 ( Ki Eun Hwhang ),김소영 ( So Young Kim ),이강규 ( Kang Kyoo Lee ),문성록 ( Sun Rock Moon ),신정현 ( Jeong Hyun Shin ),조경화 ( Kyung Hwa Cho ),이미경 ( Mi Kung Lee ),이삼 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.69 No.2
Background: Autophagy is an important adaptive mechanism in normal development and in response to changing environmental stimuli in cancer. Previous papers have reported that different types of cancer underwent autophagy to obtain amino acids as energy source of dying cells in nutrient-deprived conditions. However, whether or not autophagy in the process of lung cancer causes death or survival is controversial. Therefore in this study, we investigated whether nutrient deprivation induces autophagy in human H460 lung cancer cells. Methods: H460, lung cancer cells were incubated in RPMI 1640 medium, and the starved media, which are BME and RPMI media without serum, including 2-deoxyl-D-glucose according to time dependence. To evaluate the viability and find out the mechanism of cell death under nutrient-deprived conditions, the MTT assay and flow cytometry were done and analyzed the apoptotic and autophagic related proteins. It is also measured the development of acidic vascular organelles by acridine orange. Results: The nutrient-deprived cancer cell is relatively sensitive to cell death rather than normal nutrition. Massive cytoplasmic vacuolization was seen under nutrient-deprived conditions. Autophagic vacuoles were visible at approximately 12 h and as time ran out, vacuoles became larger and denser with the increasing number of vacuoles. In addition, the proportion of acridine orange stain-positive cells increased according to time dependence. Localization of GFP-LC3 in cytoplasm and expression of LC-3II and Beclin 1 were increased according to time dependence on nutrient-deprived cells. Conclusion: Nutrient deprivation induces cell death through autophagy in H460 lung cancer cells.