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자궁경부암 세포주에서 cisplatin의 세포독성에 미치는 glutathione 투여 시간의 효과
조영신 ( Jo Yeong Sin ),노형균 ( No Hyeong Gyun ),안태규 ( An Tae Gyu ),한세준 ( Han Se Jun ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.1
목적 : 이번 연구의 목적은 cisplatin에 의해 야기된 인간 자궁경부암 세포의 독성에 대한 glutathione의 시간에 따른 영향을 규명하기 위한 것이었다. 연구 방법 : 인간 자궁경부암세포 (SiHa: squamous cell carcinoma cell, CaSki: epidermoid metastatic carcinoma cell)는 RPMI1640 media에서 배양되었고 cisplatin (2-50 ㎛/㎖ 투여 1시간 전과 후에 환원된 g Objective : The purpose of this study is to determine the time-dependant effects of Glutathione on the Cisplatin-induced cytotoxicity of human cervical carcinoma cells. Methods : Two human cervical carcinoma cells, SiHa (squamous cell carcinoma cell), and
담도 협착에서 종양 특성과 솔질세포검사 순서에 따른 진단 정확도
조영걸 ( Yeong Geol Jo ),이태훈 ( Tae Hoon Lee ),조현득 ( Hyun Deuk Cho ),박상흠 ( Sang Heum Park ),박재만 ( Jae Man Park ),조영신 ( Young Sin Cho ),정윤호 ( Yunho Jung ),정일권 ( Il Kwun Chung ),최현종 ( Hyun Jong Choi ),문종호 ( 대한소화기학회 2014 대한소화기학회지 Vol.63 No.4
Background/Aims: There are few data supporting the diagnostic yield of brush cytology depending on the order of cytologic reparation method or the location or shape of tumors in biliary strictures. We investigated diagnostic yields and variations n brush cytology with direct smear and cell-block preparations according to sampling preparation sequence and tumor location nd shape in biliary strictures. ethods: Patients who had undergone ERCP with tissue sampling between August 2009 and April 2013 were analyzed etrospectively. Group A was examined using brush cytology with direct smear followed by cell-block with or without biopsy, hile the reverse order was performed for group B. esults: Among 138 enrolled patients, 92 patients (A: 36, B: 56) underwent both brush cytology with direct smear and cell-block reparations. No differences in sensitivity, specificity, or accuracy were observed according to the sampling preparation method nd the location or shape of tumors in biliary strictures. The cellularity observed from brush cytology with direct smear was etter than that from cell-block according to the location of the tumor (p<0.01). The diagnostic yield was increased in both roups with addition of an endobiliary biopsy. onclusions: No difference in diagnostic accuracy was observed between the sequences of preparation for brush cytology ith direct smear and cell-block techniques. Brush cytology showed better cellularity for diagnosis.
Sheehan`s 증후군 환자에서 발생한 만성 저나트륨혈증
김범윤 ( Kim Beom Yun ),류봉관 ( Lyu Bong Gwan ),임태영 ( Im Tae Yeong ),최동현 ( Choe Dong Hyeon ),김현리 ( Kim Hyeon Li ),정종훈 ( Jeong Jong Hun ),조영신 ( Jo Yeong Sin ) 대한내과학회 2003 대한내과학회지 증례 특집호 65-5 부록3 Vol.0 No.-
Sheehan`s syndrome has been attributed to ischemic damage of the pituitary gland or hypothalamic-pituitary stalk during the peripartum period. Well-described clinical features of Sheehan`s syndrome include hypothyroidism, growth hormone deficiency, hypogo