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담도 협착에서 종양 특성과 솔질세포검사 순서에 따른 진단 정확도
조영걸 ( Yeong Geol Jo ),이태훈 ( Tae Hoon Lee ),조현득 ( Hyun Deuk Cho ),박상흠 ( Sang Heum Park ),박재만 ( Jae Man Park ),조영신 ( Young Sin Cho ),정윤호 ( Yunho Jung ),정일권 ( Il Kwun Chung ),최현종 ( Hyun Jong Choi ),문종호 ( 대한소화기학회 2014 대한소화기학회지 Vol.63 No.4
Background/Aims: There are few data supporting the diagnostic yield of brush cytology depending on the order of cytologic reparation method or the location or shape of tumors in biliary strictures. We investigated diagnostic yields and variations n brush cytology with direct smear and cell-block preparations according to sampling preparation sequence and tumor location nd shape in biliary strictures. ethods: Patients who had undergone ERCP with tissue sampling between August 2009 and April 2013 were analyzed etrospectively. Group A was examined using brush cytology with direct smear followed by cell-block with or without biopsy, hile the reverse order was performed for group B. esults: Among 138 enrolled patients, 92 patients (A: 36, B: 56) underwent both brush cytology with direct smear and cell-block reparations. No differences in sensitivity, specificity, or accuracy were observed according to the sampling preparation method nd the location or shape of tumors in biliary strictures. The cellularity observed from brush cytology with direct smear was etter than that from cell-block according to the location of the tumor (p<0.01). The diagnostic yield was increased in both roups with addition of an endobiliary biopsy. onclusions: No difference in diagnostic accuracy was observed between the sequences of preparation for brush cytology ith direct smear and cell-block techniques. Brush cytology showed better cellularity for diagnosis.