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RISS 인기검색어
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- 저자 : 조길현(Kil Hyeon Cho) (검색결과 3 건)
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이영민(Young Min Lee),오경석(Kyung Seok Oh),조길현(Kil Hyeon Cho),장현정(Hyeon Jung Jang),이상혁(Sang Hyuk Lee),설상영(Sang Yong Seol),정정명(Jung Myung Chung),최하진(Ha Jin Choi),김찬환(Chan Hwan Kim) 대한내과학회 1996 대한내과학회지 Vol.50 No.3
N/A Objectives: Gastric dysplasia is defined as a lesion characterized by cellular atypia, abnormal differentiation and disorganized architecture without showing malignant nature in histology. Even though it was known as a precursor of gastric cancer, there were few studies in clinical and biological aspect in practice. Because the early detection of gastric cancer is very important, we have evaluated the risk of gastric carcinoma following the gastric dysplasia in prevention of gastric cancer. Methods: The authors evaluated the clinical and histological findings of 27 cases of gastric dysplasia for at least 3-12 months among 38 cases of gastric dysplasia and which confirmed from January 1992 to June 1994. Results: The sex distribution of 38 cases with gastric dysplasia was that men were 29 cases and women were 9 cases. The Highest incidence was above 6th decades(30cases) in age. Twenty seven cases of gastric dysplasia could be followed prospectively. Each histologic findings were as follow, mild dysplasia 12 cases, moderate dysplasia 7 cases and severe dysplasia 8 cases respectively. The endoscopic findings showed erosion 6 cases(16%), flat lesion 8 cases(21%), ulcer 10 cases(26%), polypoid lesion 14 cases(37%) respectively, The evolution of dysplasia was regression 4 cases, persistence 4 cases, progression 3 cases, cancer 1 case(9%) in mild dysplasia and regression 2 cases, persistence 2 cases, progression 1 case, cancer 2 cases(29%) in moderate dysplasia. In eight severe dysplasia, 1 case of regression, 3 cases of persistence and 4 cases of cancer(50%) were developed. Polypectomy was performed in 12 cases and 1 case was regressed from severe dysplasia after mucosal resection. In 27 cases of gastric epithelial dysplasia, gastric cancers were developed in 7 cases(26%) and early gastric cancers were 4 cases(57%) among them and the most common lesion was ulcer(5 cases). Conclusion: Gastric dysplasia should be strictly followed up with repeated endoscopic examination as well as treated the adequate endoscopic procedure for the prevention of progression or the risk of developing cancer.
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뇌정맥 혈전증과 습관성 자연유산이 각각 합병된 발작성 야간 혈색소뇨증 2례
김인호,류승환,김규환,조길현,김호철,손창학 인제대학교 1995 仁濟醫學 Vol.16 No.4
발작성 야간 혈색소뇨증은 후천성 만성 용혈성 혈액질환으로서 다양한 임상 경과를 취하므로 진단이 늦어지거나 다른 질환으로 진단되는 경우가 많으며, 혈전증은 치명적인 합병증이다. 저자들은 뇌정맥 혈전증과 습관성 자연유산 후 2번의 자궁내 태아사망이 합병된 발작성 야간 혈색소뇨증 2례를 경험하였기에 보고하는 바이다. Paroxysmal nocturnal hemoglobinuria(PNH) is an uncommon acquired clonal disorder characterized by sensitive populations of erythrocytes, granulocytes, and platelets with increased susceptibility to complement-mediated lysis. Thrombosis, as complication of PNH, are common in the extremities, mesentery, portal system, or the cerebral venous system. Cerebral thrombosis is a major cause of death in patient with PNH, but only a few cases have been reported. Pregnancy in patient with PNH has been reported to have increased frequency of miscarriage, spontaneous abortion, hemolytic crisis, worsening of bone marrow aplasia and deep vein thrombosis. We report two cases of PNH complicated with cerebral thrombosis or spontaneous abortion. The first case is 21-year-old female who developed cerebral venous thrombosis during clinical follow-up. The second case is 36-year-old female who was admitted because of iron deficiency anemia with 5 times repeated spontaneous abortion.
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이상혁,정정명,설상영,옥승철,정준용,조길현 대한소화기내시경학회 1995 Clinical Endoscopy Vol.15 No.1
Endoscopic injection sclerotheraphy(EIS) was an effective method for treatment of bleeding esophageal varices. However, it might be associated with some undesirable complications. Endoscopic variceal ligation(EVL) is a recently developed method for control of active variceal bleeding and eradicating esophageal varices with similar efficacy and minimal risk of complications compare to EIS. We performed EVL in 40 patients who had recently bled from esophageal varices. Total 198 variceal ligations were performed during 64 separate EVL session. Control rate of acute bleeding was 90%(36 of 40patients) and 4 patients died after EVL because of failure of bleeding control. Rebleeding following initiation of EVL occured in 5 patients-three patients were successfully controlled by EVL, one patient was controlled but eradication was impossible and one patient died. Varices were eradicated or reduced to grade I in 31(86.1% ) of 36 survivors by 1-9 ligation(mean 5.0) in l-4 EVL sessions(mean 1.6). After EVL, there were mild complications-mild substernal discomfort in 4 patients, mild dysphagia in 2 patients and fever in 2 patients. These results suggest that EVL is a safe and effective method for treatment of bleeding and eradication of esophageal varices with less complication.
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