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포스터 전시 : 하부위장관 ; 중심부궤양을 동반한 위 점막하종양으로 오인된 횡행결장암의 위 직접 전이 1예
조근종 ( Jo Geun Jong ),김현재 ( Kim Hyeon Jae ),길욱현 ( Gil Ug Hyeon ),남유정 ( Nam Yu Jeong ),김진수 ( Kim Jin Su ),이지인 ( Lee Ji In ),한상우 ( Han Sang U ),김성훈 ( Kim Seong Hun ),박지찬 ( Park Ji Chan ),정정조 ( Jeong Jeon 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<서론> 위 점막하 종양은 점막교가 특징적으로 관찰되며 정상과 같은 양상의 점막소견을 보인다. 횡행결장암이 위로 직접 전이한 전이위암의 경우 점막하종양 양상으로 나타날 수 있고 이때 위결장누공을 형성할 수 있다. 위결장누공은 위궤양, 외상, 감염 등과 위와 대장의 악성 종양에 의해 발생하는 합병증으로 최근 위암과 대장암이 조기진단되면서 점차 감소하고 있다. 이러한 위결장누공을 형성하는 횡행결장암의 위 직접 전이는 국내에서 드물게 보고되고 있다. 저자들은
단순반복염기서열의 변이 형태에 따른 위암 내시경 조직의 유전자형 분류
최영덕,최상욱,전은정,정정조,민기옥,이강훈,이성,유문간,Choi Young Deok,Choi Sang Wook,Jeon Eun Jeong,Jeong Jeong Jo,Min Ki Ouk,Lee Kang Hoon,Lee Sung,Rhyu Mun Gan 대한위암학회 2004 대한위암학회지 Vol.4 No.2
Purpose: Individual gastric cancers demonstrate complicated genetic alterations. The PCR-based analysis of polymorphic microsatellite sequences on cancer-related chromosomes has been used to detect chromosomal loss and microsatellite instability. For the purpose of preoperative usage, we analyzed the correspondance rate of the microsatellite genotype between endoscopic biopsy and surgical specimens. Materials and Methods: Seventy-three pairs of biopsy and surgical specimens were examined for loss of heterozygosity and microsatellite instability by using 40 microsatellite markers on eight chromosomes. Microsatellite alterations in tumor DNAs were classified into a high-risk group (baselinelevel loss of heterozygosity: 1 chromosomal loss in diffuse type and high-level loss of heterozygosity: 4 or more chromosomal losses) and a low-risk group (microsatellite instability and low-level loss of heterozygosity: 2 or 3 chromosomal losses in diffuse type or $1\∼3$ chromosomal losses in intestinal type) based on the extent of chromosomal loss and microsatellite instability. Results: The chromosomal losses of the biopsy and the surgical specimens were found to be different in 21 of the 73 cases, 19 cases of which were categorized into a genotype group of similar extent. In 100 surgical specimens, the high-risk genotype group showed a high incidence of nodal involvement (19 of 23 cases: $\leq$5 cm; 23 of 24 cases: >5 cm) irrespective of tumor size while the incidence of nodal involvement for the low-risk genotype group depended on tumor size (5 of 26 cases: $\leq$5 cm; 18 of 27 cases: >5 cm). Extraserosal invasion was more frequent in large-sized tumor in both the high-risk genotype group ($\leq$5 cm: 12 of 23 cases; >5 cm: 23 of 24 cases) and the low-risk genotype group ($\leq$5 cm: 7 of 26 cases; >5 cm: 16 of 27 cases). The preoperative prediction of tumor invasion and nodal involvement based on tumor size and genotype corresponded closely to the pathologic tumor stage (ROC area >0.7). Conclusion: An endoscopic biopsy specimen of gastric cancer can be used to make a preoperative genetic diagnosis that accurately reflect the genotype of the corresponding surgical specimen.
증례 : 선택적 동맥내 칼슘주입법으로 진단된 Zollinger-Ellison 증후군 1예
송홍석 ( Hong Seok Song ),정정조 ( Jeong Jo Jeong ),송경섭 ( Kyung Sup Song ),전은정 ( Eun Jung Jeon ),지병수 ( Byoung Soo Jie ),전연주 ( Yeon Joo Chun ),최상욱 ( Sang Wook Choi ) 대한내과학회 2007 대한내과학회지 Vol.72 No.5
저자들은 내원 일주일 전부터 시작된 상복부 동통과 속쓰림을 주소로 내원한 60세 남자에서 상부위장관 내시경 시행 결과 역류성 식도염과 십이지장 구부 이후의 다발성 궤양을 보이고 공복 혈청 가스트린치가 1,470 pg/mL 이상으로 현저히 상승되어 산발성 Zollinger-Ellison 증후군으로 진단하였고, 복부 전산화단층촬영과 선택적 동맥내 칼슘 주입법으로 종양의 위치 파악에 성공한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Zollinger-Ellison syndrome is a very rare disease that`s caused by tumor having gastrin-producing cells, and this is accompanied by hypergastrinemia leading to gastric acid hypersecretion, peptic ulcer and their complications. A 60-year-old man presented with epigastric pain and soreness he had experienced for 7 days. The endoscopic findings showed reflux esophagitis and multiple active ulcers at the antrum, the duodenal bulb and the 2nd and 3rd portions of the duodenum. The fasting serum gastrin level was markedly elevated above 1,470 pg/mL and this was consistent with the findings of gastrinoma. We confirmed the presence of gastrinoma via the abdomen CT scan and selective intra-arterial calcium injection. This is the first Korean case report of gastrinoma that was localized by selective intra-arterial calcium injection. (Korean J Med 72:529-535, 2007)
광주지역 폐수배출사업장의 수질오염 미규제물질 실태조사 - 음이온류와 알킬페놀류를 대상으로 -
이우진 ( Woo-jin Lee ),서동주 ( Dong-ju Seo ),정연재 ( Yeon-jae Jeong ),박미애 ( Mi-ae Park ),박주현 ( Ju-hyun Park ),전홍대 ( Hong-dae Jeon ),이윤국 ( Youn-goog Lee ),서광엽 ( Gwang-yeob Seo ),정정조 ( Cheong-jo Cheong ),김난희 ( 한국환경기술학회 2023 한국환경기술학회지 Vol.24 No.1
In this study, anions (Chloride ion, Sulfuric acid ions) and alkylphenols (Nonylphenol and Octylphenol) were analyzed for wastewater discharge facilities to investigate the emission industry of unregulated water pollutants. Chloride ion showed high concentrations in the “Textile and leather processing”, “plating” facilities and the concentration range was 5.9~1,178.1 mg/L. Sulfate ion were detected at high concentrations in “Battery and semiconductor”, “petrochemical” industry and the concentration range was 2.6~7,761.0 mg/L. Nonylphenol was detected at a high concentration in the “Repair and car wash” facility and the concentration range of nonylphenol was 0.210~114.871 ug/L. Octylphenol was detected in high concentrations in the industries of “Repair and car wash”, “steel and metal processing”, “plating” facility and the concentration range of octylphenol was 0.193~170.113 ug/L.
염주옥 ( Ju Ok Yeom ),윤승배 ( Seung Bae Yoon ),김재경 ( Jae Gyung Kim ),오정환 ( Jung Hwan Oh ),전은정 ( Eun Jung Jeon ),정정조 ( Jeong Jo Jeong ),최상욱 ( Sang Wook Choi ),이성 ( Seong Lee ) 대한소화기학회 2009 대한소화기학회지 Vol.53 No.6
Hepatocellular calcinoma (HCC) is the fifth most common cancer and the third leading cause of cancer-related deaths worldwide. It is important to diagnose HCC exactly before management is attempted. But, the clinical presentations and radiologic findings of liver abscess, HCC, and metastatic tumor to the liver may be quite similar, and procedures such as serum tumor marker assay, computerized tomography, and ultrasonography of the liver cannot make a specific diagnosis. We report a case of HCC successfully diagnosed by surgery which was misconceived as liver abscess and not improved by medical treatment. (Korean J Gastroenterol 2009;53:378-382)