http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
정서율 국민대학교 한국학연구소 2024 한국학논총 Vol.61 No.-
This study delves into the cultural property designation system under the "Preservation Decree" during the Japanese colonial era in Korea (1930s-40s) and its impact on the current "Cultural Heritage Protection Act" in South Korea. The Republic of Korea's present cultural property system reflects elements from the colonial "Preservation Decree," especially in the cultural property classification and designation systems. Properties designated by the Japanese Government-General are now considered nationally designated cultural assets in Korea. Understanding the colonial period's preservation policy is crucial for comprehending the current cultural property framework. The need for a new cultural property law in colonial Korea arose with Japan's implementation of the "National Treasure Preservation Act" in 1929. Incidents of relic theft and site destruction prompted public demand for a preservation law. In response, the "Preservation Decree" was promulgated in 1933, combining relevant Japanese laws. It limited preservation to cultural properties designated by the Japanese Governor-General, justifying colonial rule but allowing arbitrary interpretation due to excessive discretion. The designation system led to a survey of potential cultural assets in colonial Korea, but not all surveyed properties were designated. Political and administrative reasons led to the exclusion of publicly recognized treasures or historical monuments from designation. The preservation committee, involving academic experts and high-ranking officials, saw Governor-General's officials compromising cultural values for industrial development or colonial rule. This issue manifested in the removal of cultural asset designations and changes in status. While the preservation policy aimed to advocate for cultural property preservation, it remained within the colonial rule framework. The Governor-General's selective preservation policy ultimately resulted in the destruction of numerous cultural properties in colonial Korea, as they were excluded from protection.
김윤희,김은영,Isabel Rodriguez,남연희,정서율,홍빈나,정세영,강동호 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.5
Changing consumption patterns and increasing health awareness, especially in Europe, are resulting in an increased demand for sesame seeds. In 2016, Asia imported the highest quantity of sesame seeds, followed by Europe and North America. We examined, for the first time, the effects of treatment with sesame oil and sesamin in hearing impairment models. Sesame oil exhibited an ameliorative effect on auditory impairment in a hair cell line in zebrafish and mice. In ototoxic zebrafish larvae, neuromasts and otic cells increased in numbers because of sesame oil. Furthermore, auditory function in noise-induced hearing loss (NIHL) was studied through auditory brainstem response to evaluate the therapeutic effects of sesame oil. Sesame oil reduced the hearing threshold shift in response to clicks and 8, 16-kHz tone bursts in NIHL mice. Auditory-protective effect of sesame oil was seen in zebrafish and mice; therefore, we used chromatographic analysis to study sesamin, which is the major effective factor in sesame oil. To investigate its effects related to auditory function, we studied the hearing-related gene, Tecta, using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide (MTT) assay. Auditory cell proliferation was induced by treatment with sesame oil and sesamin using Tecta (Tectorin Alpha) regulation. The expression of Tecta increases in the apex area of the cochlear hair cells as they grow, and their activity is enhanced by sesame oil and sesamin. These results provide a novel mechanistic insight into the sesame oil activities and suggest that sesamin, the key constituent in sesame oil, is responsible for its auditory function related benefits, including protection of auditory cells and reversal of their impairments.
남윤희,문효원,이영로,김은영,Isabel Rodriguez,정서율,Rodrigo Castañeda,박지호,정세영,홍빈나,강동호 고려인삼학회 2019 Journal of Ginseng Research Vol.43 No.2
Background: Diabetic sensorineural damage is a complication of the sensory neural system, resulting from long-term hyperglycemia. Red ginseng (RG) has shown efficacy for treatment of various diseases, including diabetes mellitus; however, there is little research about its benefit for treating sensorineural damage. Therefore, we aim to evaluate RG efficacy in alloxan-induced diabetic neuromast (AIDN) zebrafish. Methods: In this study, we developed and validated an AIDN zebrafish model. To assess RG effectiveness, we observed morphological changes in live neuromast zebrafish. Also, zebrafish has been observed to have an ultrastructure of hair-cell cilia under scanning electron microscopy. Thus, we recorded these physiological traits to assess hair cell function. Finally, we confirmed that RG promoted neuromast recovery via nerve growth factor signaling pathway markers. Results: First, we established an AIDN zebrafish model. Using this model, we showed via live neuromast imaging that RG fostered recovery of sensorineural damage. Damaged hair cell cilia were recovered in AIDN zebrafish. Furthermore, RG rescued damaged hair cell function through cell membrane ion balance. Conclusion: Our data suggest that RG potentially facilitates recovery in AIDN zebrafish, and its mechanism seems to be promotion of the nerve growth factor pathway through increased expression of topomyosin receptor kinase A, transient receptor potential channel vanilloid subfamily type 1, and mitogenactivated protein kinase phosphorylation.