Clinical relevance of the CA 125 assay in monitoring of Epithelial ovarian cancer patients

정민형,이선경 대한산부인과학회 2003 대한산부인과학회 학술대회 Vol.89 No.-

고래불 해안사구에서 염생식물의 공간분포

정민형,김석철,홍보람,이규송 한국환경생물학회 2017 환경생물 : 환경생물학회지 Vol.35 No.3

Factors affecting spatial distribution of halophytes were analyzed in June 2012 at the Goraebul coastal dunes. In the Goraebul sand dune, distribution of halophytes was divided into three groups. The first group belonging to Elymus mollis, Carex kobomugi, Calystegia soldanella, Ixeris repens and Glehnia littoralis was distributed in the ridge of primary sand dune and dune slack. The second group belonging to Lathyrus japonicus and Zoysia macrostachya was distributed in the dune slack. The third group belonging to Pinus thunbergii, Vitex rotundifolia and Linaria japonicus was distributed in the pine forest of the secondary sand dune. E. mollis, C. kobomugi, C. soldanella, I. repens and G. littoralis was distributed in relatively unstable habitat of sand dunes due to the large amount of sand movement. V. rotundifolia was distributed in a relatively stable habitat. Factors that have the greatest influence on distribution of halophytes in the Goraebul sand dunes are distance from the seashore, topography, and the pine forest. The Goraebul sand dune is a relatively well-preserved area with minimal human intervention. Therefore, different distribution of physico-chemical factors by natural processes is essential to spatial distribution of halophytes than other sand dunes in Korea. Significant natural processes in the Goraebul sand dunes were advance and retreat of coastlines from waves, erosion and sedimentation of sand due to wind and waves, and dispersal of seawater.

Effect of gut symbiont Caballeronia insecticola on life history and behavioral traits of male host Riptortus pedestris (Hemiptera: Alydidae)

정민형,이두형 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.2

Symbiotic microorganisms can affect physiological conditions of host insects, subsequently altering life history and behavioral traits of their host insects. The bean bug, Riptortus pedestris, is a polyphagous insect pest which established an insect-microbe symbiosis with the bacterial genus Caballeronia. To understand how Caballeronia bacteria could affect life history and behavioral traits of host R. pedestris, we evaluated morphometric charac teristics, feeding behavior, dispersal behavior, and survivorship of symbiotic and apo-symbiotic adult male R. pedestris. From morphometric character evaluation, symbiotic male displayed significantly greater body weight and larger body size than apo-symbiotic males. Moreover, symbiotic males had significantly larger hind legs utilized as a weapon in male-male competition for R. pedestris. From feeding behavior evaluation, symbiotic male consumed greater amount of food with lesser feeding attempt, resulting in significantly enhanced feeding efficiency. Dispersal behavior evaluation revealed that symbiotic male displayed significantly enhanced move ment and flight capacity compared to apo-symbiotic male. In particular, flight capacity of symbiotic male increased ca. 170 times compared to apo-symbiotic males, yielding 1.39 km flight distance an average. There was no significant difference in survivorship between symbiotic and apo-symbiotic male R. pedestris, yielding 97 % and 90 % of survivorship over 60 days evaluation, respectively. However, titer of Caballeronia symbiont in male R. pedestris gradually decreased during the adult period evaluated. Our results demonstrated how gut microbe could affect the fitness-related and dispersal ability of male host insect.

점토층 위 모래지반의 지지력비에 따른 얕은 기초의 지지력 거동

정민형,신효희,이송 한국구조물진단유지관리공학회 2011 한국구조물진단유지관리공학회 논문집 Vol.15 No.1

연약 점성지반 위에 상대적으로 낮은 하중의 구조물이 얹어질 때, 상부에 모래층을 두어 지지력을 증진시킬 수 있다. 이와같은 점토 위 모래층이 놓이는 조건에 대한 지지력 검증은 현장에서 평판재하시험 등을 통해 지지력 검증이 어렵기 때문에 설계단계에서부터 정확한 지지력 예측이 필요하다. 따라서, 본 연구는 점토 위 모래층이 놓이는 지반의 지지력 거동을 파악하기 위해 2차원 실내토조실험과 FEM 해석을 수행하였다. 주요 인자로 깊이비 H/B와 지지력비 qc/qs를 선정하여, 모래층 높이, 점토의 비배수전단강도 그리고 재하 폭을 변수로하였다. 그 결과, 실내토조실험은 FEM 해석과 적합성이 상당히 높게 나타났다. 이론식과의 비교에 있어서 보다 최신 연구인Okamura et al.(1998)의 메커니즘보다 관입전단 메커니즘과 그 유사성이 크게 나타났으며, 하중확산 메커니즘의 적용성을 위하여 등가하중확산각을 제시하였다. 또한, qc/qs에 대하여 무차원 단위의 한계깊이비 Hf의 선형 회귀식을 제안하였다. When a structure which has relatively low load constructs on soft clay, the bearing capacity of the ground will be improved by sand overlying clay. In this condition, verifying the bearing capacity is difficult from the P.B.T etcetera in the in-situ. So, it is needed to estimate precise bearing capacity in the design process. In this study, 2-dimensional chamber tests and FEM analyses are conducted to evaluate behavior of bearing capacity for shallow foundations on a sand overlying clay. Because depth ratio H/B and bearing capacity ratio qc/qs are selected as main factors, height of a sand, undrained shear strength of a clay and width of a loading are designated as variables. Results from chamber tests are very similar with those of FEM analyses. And it shows that punching shear mechanism is more suitable than the equation of Okamura et al.(1998). To make continual application of load spread mechanism, the equivalent load spread angle is proposed for H/B and qc/qs. Also, the linear regression equation of critical depth ratio Hf is suggested for qc/qs.

선원의 직무만족에 관한 연구

정민형,신영란 한국항해항만학회 2021 한국항해항만학회 학술대회논문집 Vol.2021 No.5

Population dynamics of mosquitoes (Diptera: Culicidae) and their disease-harboring rates in Gyeonggi province, South Korea

정민형,Kim Soowan,이두형 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.2

Population dynamics and species composition of mosquitoes were monitored in a suburban residential area and rural areas, including a migratory bird refuge area and a cattle farm area, from 2017 to 2019. Mosquitoes were collected every two weeks using one BG sentinel trap and two black-light traps in a suburban residential area and a migratory bird refuge area, and one black-light trap in a cattle farm area from March to November. From the surveillance, a total of 13,267, 9,697 and 6,688 mosquitoes were collected in 2017, 2018, and 2019, respectively. The peak of the mosquito population was observed in August and September in both the suburban residential area and rural areas. In general, Culex pipiens pallens was the dominant species in the suburban residential area, whereas Aedes vexans nipponii and Anopheles spp. were the most dominant in the rural areas. Collected mosquitoes were pooled into groups for each collection site and species to investigate flavivirus harboring. Three pools were positive for Japanese encephalitis virus type V, one pool was positive for Chaoyang virus, and six pools were positive for Culex flavi virus from the 731 pools tested. When total numbers of collected mosquitoes were further analyzed by linear regression analysis for their interaction with ambient temperature and relative humidity, the number of mosquitoes were significantly affected by the ambient temperature. In contrast, relative humidity was significantly affecting the total number of mosquitoes only for the migratory bird refuge area.

Protecting a Woman’s Skeleton

정민형,김흥열 대한골다공증학회 2010 Osteoporosis and Sarcopenia Vol.8 No.3

Osteoporosis, the most common bone disease, is a silent condition resulting in increased fracture risk. Preventive methods for adulthood, early recognition of osteoporosis followed by timely and effective management can reduce fracture risk. Several pharmacologic therapies are currently available, and when choosing from the available options, clinicians should consider the efficacy and safety profiles of each therapy as well as the individual patient’s needs and overall health. Ideally, therapy should satisfy multiple criteria: fracture protection across multiple skeletal sites; rapid onset of action to maximize the timing of fracture protection; and minimal side effects with proven long-term safety.

호르몬 요법이 뼈에 미치는 영향

정민형 대한골다공증학회 2008 Osteoporosis and Sarcopenia Vol.6 No.2

성호르몬은 성인에서 뼈의 발달과 유지에 필수적이며 폐경기에 동반되는 에스트로젠의 부족은 폐경기 여성에서 골다공증을 유발하는 주요 원인이다. 골다공증은 매우 흔한 질환으로 매년 수백만 명에게 예방 가능한 골절을 유발한다. 특히 여성에서는 남성에 비해 노화 및 성호르몬의 감소에 의해 골다공증이 발생할 가능성이 높다. 수십 년 동안 폐경기 호르몬 치료는 폐경기 여성에서 골다공증을 예방하고 치료하는 주요한 방법이었으나 더불어 유방암, 정맥 색전증, 뇌졸중, 관상동맥질환을 유발하기도 하였다. 최근에는 호르몬 치료이외의 골다공증 치료 약제들이 사용 가능해졌고 골다공증 치료를 시작하기 전 골농도, 골다공증에 의한 골절을 유발할 수 있는 다른 위험 인자 등을 고려하고 각각의 치료 방법의 장단점을 감안해 선택하고 있다. 본 저자는 여기에 최근의 골다공증 치료에 대한 여러 연구 논문의 결과를 밝혀 환자 개인적인 위험인자, 선호도, 환자의 치료 의지 등을 고려하여 치료 방법을 선택할 때 도움이 되고자 한다.

그라우팅을 병행한 강관추진공법의 현장 적용성 연구

정민형,임호정,신창섭,이송 한국구조물진단유지관리공학회 2009 한국구조물진단유지관리공학회 논문집 Vol.13 No.1

강관추진공법은 비굴착공법으로써 중소규모 관로공사에 높은 시공성과 경제성을 가지고 있기 때문에 그 사용이 빈번해지고 있다. 그러나 강관추진공법의 추진과정은 원지반이 교란되고 느슨해지는 문제를 야기하고 있다. 이는 지표침하, 지반강도 저하 및 누수 등의 문제와 연결된다. 이에 본 연구는 강관추진과 동시에 그라우팅을 시행하는 그라우팅을 병행한 강관추진공법의 현장 적용성을 알아보고자 한다. 그 방법으로 그라우팅을 병행한 강관추진공법과 기존강관추진공법을 동일 지반에 시공하였다. 지표침하 계측, 현장밀도, GPR 물리탐사 그리고 대형전단실험의 결과는 그라우팅을 병행한 강관추진공법의 현장 적용성이 있음을 입증하였다. The pipe jacking method which is a non-excavation method is frequently used due to constructability and economical efficiency in a medium or small-sized pipeline construction. However, jacking process of the method still causes problems that the base ground is disturbed and loosen. These lead to surface settlement, strength decrease and leakage of water. Therefore, this study presents in-situ application of the steel pipe jacking with grouting, and it is that jacking and grouting are progressed simultaneously. To verify this, the steel pipe jacking with grouting and the existing steel pipe jacking have been constructed on the same ground condition. It has been proved that the steel pipe jacking with grouting is in-situ applicable according to results of monitoring surface settlement, in-situ density, GPR geophysical prospecting and large scale direct shear test.

마이크로시멘트 무기질계 그라우팅 ENG의 적용성 연구

정민형,김용식,정춘학,이송 한국구조물진단유지관리공학회 2010 한국구조물진단유지관리공학회 논문집 Vol.14 No.1

물유리계 그라우팅 공법은 침투주입 그라우팅으로 자주 적용되고 있으나, 시간경과에 따른 내구성 저하와 환경에 부정적 영향에 대한 문제가 부각되고 있다. 이에 마이크로시멘트계 무기질 재료의 ENG 공법이 이러한 물유리계 그라우팅 공법의 문제점을 극복하면서 우수한 침투성을 목표로 하여 개발되었다. ENG의 적용성을 파악하기 위해 체적변형시험, 용탈실험, 일축압축실험, 실내 투수실험 및 현장투수실험 그리고 중금속검출실험을 실시하였다. 그 결과 체적변형, 용탈량, 일축압축강도는 물유리 공법보다 월등히 우수하였으며, 투수실험에 있어서도 차수효과가 나타났다. 또한 중금속 검출량도 미미하여 환경에 부정적인 효과도 적을 것으로 판단된다. The Water glass grouting method has been applied frequently to penetration grouting in practice, but some problems, such as decrease of durability with the elapsed time and environmentally adverse effect, are raised recently. Hence, the Earth Natural Grouting method which uses micro cement and inorganic material is developed to overcomes those problems of the water glass grouting method, and is aimed for extensive ground injection bound. Volumetric strain test, syneresis test, unconfined compression test, triaxial permeability test, in-situ permeability test and heavy metal analysis were conducted to verify application of the ENG. As the result of tests, volumetric strain, syneresis and unconfined strength of the ENG were superior to those of the Water Glass SGR and ENG was proved to be impermeable. Also it is expected that the ENG would not have an effect on environmental pollution.