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증례 : 감염 ; 보존적 치료로 호전된 시력소실을 동반한 급성 A형 간염 1예
임민희 ( Min Hee Lim ),허상택 ( Sang Taek Heo ),김차영 ( Cha Young Kim ),배인규 ( In Gyu Bae ),김재희 ( Jae Hee Kim ),천윤홍 ( Yun Hong Cheon ),하창윤 ( Chang Yoon Ha ) 대한내과학회 2011 대한내과학회지 Vol.80 No.2S
Hepatitis A is usually a mild, self-limiting illness, but in certain cases it can develop into a severe or fatal disease. The most common symptoms of acute hepatitis A virus (HAV) infection are fever, myalgia, nausea, vomiting, jaundice, and abdominal pain. Extrahepatic symptoms are rare, especially neurologic manifestations. We investigated a 34-year-old male who presented after suffering two days of fever, chills and general myalgia. His condition gradually deteriorated and he developed sudden blindness on day nine. This blindness lasted for 20 min and at this point abnormal brain images were observed. Initial tests for immunoglobulin M anti HAV were negative. These tests were repeated, later confirming acute HAV infection. After conservative management, the individual fully recovered. We report this extremely rare acute HAV infection case with metabolic encephalopathy exhibiting transient blindness. (Korean J Med 2011;80:S305-S309)
다이어트 약물 치료 후 Candida guilliermondii에 의한 칸디다 혈증
임민희 ( Min Hee Lim ),허상택 ( Sang Taek Heo ),배인규 ( In Gyu Bae ),정용근 ( Yong Geun Jeong ),김현옥 ( Hyun Ok Kim ),고관수 ( Kwan Soo Ko ),김선주 ( Sun Joo Kim ) 대한내과학회 2009 대한내과학회지 Vol.77 No.2
Candida guilliermondii is found in sea water, animal feces, buttermilk, and beer and has been isolated from human infections, mostly of cutaneous origin. It usually causes skin and soft tissue infections and has decreased susceptibility to fluconazole. Systemic infections occur mostly in immunocompromised patients. A 38-year-old female was admitted with a 4-day fever. Her cal and family histories were unremarkable, except for obesity. She had been taking diet pills for 3 months and had undergone injection therapy into her abdomen for lipolysis for 1 month. She did not respond to empirical antibiotics. A Candida species was isolated from blood cultures and identified as C. guilliermondii based on partial LSU rRNA gene sequence analyses. She was treated with amphotericin B, and recovered completely. (Korean J 77:251-254, 2009)
Vibrio vulnificus에 의한 급성 세균성 뇌수막염 1예
김현식 ( Hyeon Sik Kim ),허상택 ( Sang Taek Heo ),배인규 ( In Gyu Bae ),임민희 ( Min Hee Lim ),김재희 ( Jae Hee Kim ),윤성은 ( Seong Eun Yun ),김선주 ( Sun Joo Kim ) 대한내과학회 2010 대한내과학회지 Vol.78 No.4
Vibrio vulnificus infects susceptible individuals who eat contaminated seafood or have an open wound that is exposed to seawater. The common symptoms are necrotizing wound infection, primary septicemia, and gastroenteritis. A 52-year-old man visited the emergency department complaining of drowsiness. Based on a cerebrospinal fluid analysis, he was diagnosed with acute bacterial meningitis. V. vulnificus was isolated from a blood culture. The patient responded to treatment with ceftriaxone and ciprofloxacin. We report a rare case of acute bacterial meningitis caused by V. vulnificus that was treated successfully. (Korean J Med 78:523-526, 2010)
복막투석 환자에서 발생한 Pantoea agglomerans에 의한 복막염 1예
김현옥 ( Hyun Ok Kim ),이현정 ( Hyeon Jeong Lee ),김동욱 ( Dong Wook Kim ),조현섭 ( Hyun Seop Cho ),임민희 ( Min Hee Lim ),장세호 ( Se Ho Chang ),박동준 ( Dong Jun Park ) 대한내과학회 2008 대한내과학회지 Vol.74 No.4
Microorganisms belonging to the genus Pantoea rarely cause infection in normal hosts, but are common in hospitalized or immunocompromised patients. Pantoea agglomerans has frequently been associated with exogenous sources such as plants, soil, water, and foodstuffs. Until now, only one case of P. agglomerans-associated peritonitis has been reported in an adult patient undergoing continuous ambulatory peritoneal dialysis (CAPD). We report a case of peritonitis due to P. agglomerans in a 55-year-old man with maintenance CAPD. Antibiotic therapy with intraperitoneal cefazolin and gentamicin led to clinical improvement.(Korean J Med 74:426-429, 2008)
대유행 인플루엔자(H1N1 2009) 감염과 연관된 폐쇄 세기관지 기질화 폐렴 1예
임민희,허상택,김호철,배인규,김재희,김인숙,김선주,고경혁 대한감염학회 2010 감염과 화학요법 Vol.42 No.2
Several types of influenza-related pneumonia have been reported. Bronchiolitis obliterans organizing pneumonia (BOOP) is a nonspecific lung injury. A 64-yearold man sought care to an emergency room due to breathing difficulties. He was diagnosed with pandemic influenza (H1N1 2009) by the real-time polymerase chain reaction (PCR) and was suspected of concomitant bacterial pneumonia. Therefore he was treated with oseltamivir and broad spectrum antibiotics. The disease progressed rapidly despite treatment, so a corticosteroid was added. The trans-bronchial lung biopsy was consistent with BOOP. Here, we investigated BOOP associated with the pandemic influenza (H1N1 2009) virus that was successfully treated with a combination of antiviral, antibacterial and corticosteroid drugs. Although BOOP associated with influenza is rare, combined disease should be suspected especially when the pneumonia does not response to antiviral agents and antibiotics.