Distinct features of dendritic cell-based immunotherapy as cancer vaccines

이채린,이명미,이인무 대한백신학회 2018 Clinical and Experimental Vaccine Research Vol.7 No.1

Dendritic cells (DCs) are the most professional antigen presenting cells that play important roles in connection between innate and adaptive immune responses. Numerous studies revealed that the functions of DCs are related with the capture and processing of antigen as well as the migration to lymphoid tissues for the presenting antigens to T cells. These unique features of DCs allow them to be considered as therapeutic vaccines that can induce immune responses and anti-tumor activity. Here, we discuss and understand the immunological basis of DCs and presume the possibilities of DC-based vaccines for the promising cancer therapy.

[우리 실험실은요!] 유기반응 및 물질개발 연구실

이채린 대한화학회 2023 화학세계 Vol.63 No.5

Thermal Compression of Copper-to-Copper Direct Bonding by Copper films Electrodeposited at Low Temperature and High Current Density

이채린,이진현,박기문,유봉영 한국표면공학회 2018 한국표면공학회 학술발표회 초록집 Vol.2018 No.6

통기형 몰딩 적용에 따른 공동주택 붙박이장의 동계 결로방지성능 평가

이채린,송승영 한국건축친환경설비학회 2019 한국건축친환경설비학회 논문집 Vol.13 No.5

The purpose of this study was to evaluate the condensation prevention performance around the apartment built-in furniture applying vent-type moldings. Recently, condensation and mold problems in apartments have been growing due to the high thermal insulation and air-tightness for energy saving. The considerable amount of moisture generated by various indoor activities such as drying clothes, cooking, and taking a shower in a living space is more likely to cause condensation in apartments, and thus spaces fitted with built-in furnitures are exposed to condensation more frequently. In this study, thermal environment around the built-in furniture with vent-type moldings was measured in actual apartment from January 3 to March 5, 2019, in order to find out the location of vents effective for preventing condensation. As results, the condensation prevention performance was better when the vents were placed on both the bottom and side or both the top and bottom of the front moldings than on the back board of the built-in furniture. The proposed design will be useful to mitigate condensation in spaces fitted with built-in furnitures.

기존 공동주택 붙박이장에서 겨울철 결로 방지를 위한보조난방장치 운전 성능 평가

이채린,이현화,임재한,송승영 한국건축친환경설비학회 2018 한국건축친환경설비학회 논문집 Vol.12 No.6

The purpose of this study was to evaluate condensation prevention for condensation vulnerable areas around built-in furniture of apartment buildings by applying auxiliary heating device. Recently, the condensation and mold problems of apartment buildings has been growing due to high insulation and high air-tightness performance for energy saving. Condensation at built-in furniture were generally found in winter at the of furniture’s back panels, adjacent surfaces of wall, floor and ceiling. These problems are related to the weather conditions and indoor room conditions in winter. To solve these problems, auxiliary heating device was developed and could be installed. The aim of paper is to analyze the thermal environment around the built-in furniture which were applied and not applied auxiliary heating device in winter. In results, it was possible to increase the surface temperature of vulnerable areas around built-in furniture by applying auxiliary heating device, and to minimize condensation problems by using the minimum device.

어머니의 낡은 앨범

이채린 대구대학교 국어교육과 2023 나랏말쌈 Vol.38 No.-

보드리야르의 소비사회 이론 관점에서 분석한 ‘인스타그램(Instagram)’

이채린 이화여자대학교 스크랜튼대학 스크랜튼학부 2017 ATE Vol.7 No.-

여자대학생의 비만식습관과 식행동에 대한 조사 연구

이채린,김순경 순천향대학교 기초과학연구소 2008 순천향자연과학연구 논문집 Vol.14 No.2

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치매 환자를 대상으로 디지털 매체 회상치료에 관한 체계적 고찰

이채린,최호빈,백승학,하은지,최진혁,유두한 대한보조공학기술학회 2023 대한보조공학기술학회지 Vol.15 No.2

목적 : 본 연구는 치매 환자들에게 적용할 수 있는 디지털 매체를 활용한 회상치료의 중재 방법과 효과를 제시하고자 한다. 연구방법 : 본 연구에서는 Google Scholar, Pubmed에서 제공되는 연구논문들 중 2012월 1월 부터 2021년 12월 까지 발표된 자료를 수집하였다. 포함 및 배제기준을 적용하여 6개의 논문이 분석대상으로 사용되었다. 이 연구들은 연구의 근거기반 질적 수준 분석모델에 따라 분류하였고 PICO로 정리하였다. 검색어는 “치매” AND “회상치료”, “dementia” AND “reminiscence therapy” AND “media” OR “digital” OR “app”로 사용하였다. 결과 : 디지털 회상치료에 대한 연구는 2015년, 2016년, 2020년은 각각 1편, 2021년은 3편, 총 6편으로 이루어져 있으며, 태블릿을 활용한 회상치료, 디지털 소프트웨어를 활용한 회상치료, 디지털 동영상을 활용한 회상치료, VR기기를 활용한 회상치료 등 다양한 매체를 활용하여 중재에 적용하였다. 디지털 회상치료를 적용하였을 때, 우울 감소, 삶의 질, 인지기능 향상의 효과가 가장 많았으며 평가도구는 MMSE(Mini-Mental State Examination)가 가장 많이 사용된 것을 확인할 수 있었다. 결론 : 디지털 매체를 활용한 회상치료의 중재 방법과 효과를 알아보고자 하였다. 태블릿을 활용한 회상치료, 디지털 소프 트웨어를 활용한 회상치료 등이 있었으며 우울 감소, 삶의 질 향상 등의 효과가 있었다. 이러한 결과를 바탕으로 추후 연구에서는 디지털 매체를 활용한 회상치료 간의 비교를 통해 어떠한 디지털 매체가 회상치료에 적용되었을 때 더 효과가 있는지 비교연구가 활발히 이루어지기를 기대한다. Objective : To investigate intervention methods and effects of Reminiscence Therapy using digital media that can be applied to persons with dementia. Methods : In this study, 6 of studies were selected according to the selection criteria using RISS and Pubmed databases. As search terms were "dementia" AND "reminiscence therapy" in Korean and "dementia" AND "reminiscence therapy" AND "media" OR "digital" OR "app" in English. The studies to be analyzed were classified according to the research-based qualitative level analysis model and summarized as PICO. Results : 6 of studies consists of 1 study each in 2015, 2016, and 2020, and 3 studies in 2021. Various digital media such as tablet, digital software, digital video, and VR devices were applied to the intervention. The effect of reducing depression, improving quality of life, and cognitive function was confirmed the most. As for the evaluation tool, MMSE was most commonly used. Conclusions : Reminiscence Therapy using a tablet and digital software were used, and there were effects such as reduction of depression and improvement of quality of life. Based on these results, it is expected that future research will actively conduct comparative research on which digital media is more effective when applied to Reminiscence Therapy.

코로나-19 팬데믹 하 도시 취약계층 노인의 우울 관련요인: 다차원적 사회적 관계요인을 중심으로

이채린,김홍수 한국노년학회 2022 한국노년학 Vol.42 No.5

The purpose of this study is to examine the level of depression and social relations of urban low income elderly during the COVID-19 pandemic, and to compare the factors related to depression according to participation or continuation of regular social activities. This study used survey data from ‘Small-area Health Disparity Reduction Project: a Health and Wellness Program for Seniors in A-gu, Seoul’, sponsored by the Korea Disease Control and Prevention Agency(KDCA) and Seoul city government. Referring to previous studies and the theoretical framework by Berkman et al.(2000), the research model investigated the relationship between depression and micro, mezzo, and macro levels of social relation factors. As a result, 15% of the study participants reported depression. Social support, social activities(micro), and contact frequency with friends measured by network structure and characteristics(mezzo) was significantly associated with depression. As a result of sub-analysis, social relation factors were not associated with depression in the non-participating group. Whereas, recognized social support(micro) decreased depression in both the discontinued and sustained group. Also, in the discontinued group, contact frequency with friends and level of community awareness(macro) were the protector factors of depression. Our results suggest the need for implementation of tailored health and welfare programs considering the characteristics of social networks, and provide evidence for multidimensional approaches to promote social relations and mental health of community dwelling elderly during the pandemic. 본 연구의 목적은 코로나-19 팬데믹이 성행하는 가운데 도시 취약계층 노인들의 사회적 관계와 우울 수준을 파악하고, 정기적사회활동 참여⋅지속에 따른 우울 관련요인을 비교하는 것이다. 이를 위해 ‘서울특별시 A구 소지역 건강격차 해소 시범사업’에서 실시한실태조사 자료를 활용하였으며, 최종 분석대상은 건강⋅전허약 노인 1,217명이다. 연구모형은 Berkman et al.(2000)의 ‘사회적 관계망과건강의 연결관계 개념틀’과 선행문헌 고찰을 바탕으로 미시, 중시, 거시 수준의 사회적 관계요인과 우울의 관계를 살펴보았다. 연구결과, 연구 참여자의 약 15%가 우울을 보고하였으며, 사회적 지지와 사회활동 수준(미시) 및 친구 연락 빈도로 측정된 관계망 구조와특성(중시)이 우울과 유의한 연관성을 보였다. 사회활동 참여⋅지속 여부에 따른 하위분석 결과, 미참여군에서 사회적 관계요인들은우울을 유의하게 감소시키지 못하는 것으로 나타났다. 반면 중단군과 지속군 모두에서 인지된 사회적 지지(미시)는 우울과 유의한음의 관계가 있었다. 또한 중단군의 경우, 친구 연락 빈도(중시)와 긍정적 지역사회 인식(거시)가 우울에 대한 보호 요인이었다. 연구결과는 팬데믹 하의 지역사회 거주 노인의 정신건강을 위해 사회적 관계를 유지 및 증진할 수 있는 다차원적 접근이 필요하다는 근거를제시하며, 향후 각 노인의 사회적 관계망의 특성을 고려한 맞춤형 보건⋅복지사업의 기획과 실행의 필요함을 시사한다.