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      • KCI우수등재

        가치동맹의 패러독스 - 냉전과 신냉전 사이의 한반도

        이유철 비판사회학회 2023 경제와 사회 Vol.- No.140

        This study aims to diagnose the current state of the Korean Peninsula by examining the transitional international order. The strategic competition between the United States and China and military conflicts such as the war in Ukraine and the war in Israel are raising fundamental questions about the liberal international order that has dominated the post-war order and the leadership of the United States in leading it. The U.S. Indo-Pacific strategy can be understood as a response to those challenges ahead. The problem is that the Korean Peninsula has been caught in the magnetic field of this grand strategy (trilateral cooperation between the United States, South Korea, and Japan). Yun Suk-yeol administration’s Korean version of the Indo-Pacific Strategy, along with the Value Alliance Doctrine, was intended to counter North Korea’s nuclear weapons development programme, but the magnetic field pushed it into a realm beyond its control, bringing China, Russia and North Korea closer together and perpetuating the Korean Question. In order to escape the magnetic field of great power rivalry, this article shed light on the imagination to abandon factional epistemologies and establish new non-aligned spaces.

      • KCI등재

        A revision of the genus Littorina (Mollusca: Gastropoda) in Korea

        이유철,최영재,Elizabeth M. A. Kern,신영헌,김태호,박중기 한국통합생물학회 2018 Animal cells and systems Vol.22 No.6

        Littorina Férussac, 1822 is an abundant genus of small gastropods found in the upper littoral zone of rocky seashores worldwide. Although ecologically important, shell-based species identification in this genus is challenging due to phenotypic variation in shell morphology and lack of diagnostic characters among morphologically similar species. In this study, we revised the taxonomy of Korean Littorina species using morphological characters (shell and radula) and cox1 mitochondrial DNA sequences for three Korean species: L. brevicula, L. sitkana, and L. horikawai. Results suggest that L. sitkana was erroneously reported as L. kasatka in a previous study. A new record for Littorina horikawai (Matsubayashi & Habe in Habe, 1979), previously unknown from Korea, is described, which can be distinguished from L. sitkana by the presence of alternating white and brown spiral ribs on each whorl. Comparison of the mtDNA cox1 gene sequences shows very low intraspecific variation even between geographically distant populations. A phylogenetic tree supports a close relationship between L. horikawai and L. sitkana, consistent with earlier phylogenetic studies.

      • KCI등재

        자동차 산업분야의 효과적인 제조협업 구현을 위한 디지털 엔지니어링 적용 방법론에 대한 연구

        이유철,배혜림 대한산업공학회 2012 산업공학 Vol.25 No.1

        Very special and tentative considerations including emotional aspects are required to apply any new mechanism and methodologies for manufacturing fields due to several reasons. This study reviews the characteristics of manufacturing collaborations through specific cases applied digital engineering to enhance the collaboration performance in manufacturing domains. Two cases of collaboration related with automotive manufacturing process are analyzed to extract meaningful insights for better collaboration model suggestions. The first case deals the robot simulation to find out advance errors in jig and fixture design during the various welding process of body-in-whites. The effective communication protocol to share their idea and agreed schedules are essential for this collaboration. More severe requirement of collaboration between R&D and manufacturing departments are studied in the second case for e-coating process. The invisible barriers among different departments are lowered by the process application of Computer Aided Engineering which can make sure their own interesting effectively. Those technical and managerial suggestions can be used when the information system and standard process are sought to implement and update not only when innovation projects are executed.

      • Klebsiella의 항균제 내성 및 Beta-lactamase

        이유철,김광만,김정민,이제철,이상화,설성용,조동택 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.1

        목적 : Klebsiella는 많은 사람에게서 장관내 상재균총으로 존재하며, 종종 병원내에서 면역기능이 억제된 환자, 신생아 그리고 노인에게서 기회감염을 일으킨다. 많은 균주들이 감염의 치료에 흔히 사용되는 항균제에 대하여 다약제 내성을 나타내고 이들은 때때로 집단적인 원내감염을 일으키기도 한다. 대상 및 방법 : 대구 및 서울 지역의 종합병원에서 분리한 59주의 Klebsiella 균주들을 대상으로 항균제 내성 빈도 및 plasmid의 양상을 조사하고 이들 균이 산생하는 beta-lactamase의 특성을 알기 위하여 균을 파쇄, 추출한 beta-lactamase를 isoelectric focusing하여 등전점을 측정하였다. 결과 : Ampicilin 및 carbenicillin에 대하여는 47∼54주(79.7∼91.5%)가 내성을 보였으며, cephalothin, gentamicin 및 trimethoprim에 대하여는 16∼17주(27.1∼28.8%)가 내성을 보였다. Klebsiella는 크기가 2∼142 megadalton인 2∼4개의 plasmid를 가지고 있고 전달성 plasmid의 크기는 74∼142 Mdal이었다. Klebsiella균이 산생하는 beta-lactamase를 조사한 결과 TEM-1, TEM-2와 제3세대 cephalosporin에 대한 광범위의 beta-lactamase SHV-2가 검출되었다. 결론 : Beta-lactamase 효소 활성 억제물질이 광범위 beta-lactamase에 미친 영향을 조사하여 치료시에 항생제와 호소 활성 억제제를 병합 사용할 수 있는 방법을 고안하여야 할 것으로 사료된다. A total of 59 strains of Klebsiella species isolated from various clinical specimens in Taegu and Seoul was tested for the antimicrobial susceptibility and then was subjected for the characterization of R plasmids and beta-lactamases. Forty-seven to 54 strains(79.7∼91.5%) were resistant to ampicillin and carbenicillin, and 16∼17 strains (27.1∼28.8%) to cephalothin, gentamicin, and trimethoprim. One to five strains(1.7∼8.5%) were resistant to cefotaxime(Ct), ceftazidime(Cz), aztreonam(Az), and amikacin, but all strains were susceptible to moxalactam and imipenem. There was no significant difference in the frequency of resistance between the strains isolated in Taegu and those in Seoul. Klebsiella strains contained up to four plasmids per isolate and the molecular weight of plasmids ranged from two to 142 megadalton(Mdal). Twenty strains(40%) among 50 strains which were resistant to two or more antimicrobial agents, transferred the resistance to E. coli RG176, and the molecular weight of conjugate plasmids ranged 74∼142Mdal. The plasmid pKK1271(74Mdal) produced TEM-1 type beta-lactamase of pi value 5.4, and the plasmids pHK1031 and pGK1061(90Mdal) which were harbored in the Klebsiella strains DHK103 and DGK106 respectively, produed TEM-2 type beta-lactamase of pi value 5.6 which were identified by isoelectric focusing. The plasmids pKK1111 and pKK1291(124Mdal) produced extended-spectrum SHV-2 beta-lactamase (pI value 7.6) with activity against Ct, Cz, and Az.

      • Klebsiella가 보유한 아미노 배당체 항생제 변경효소 유전자의 분포

        이유철,정지인,김정민,이제철,이상화,설성용,조동택 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.1

        목적 :임상 검체에서 분리한 Klebsiella pneumoniae를 대상으로 kanamycin(Km)과 gentamicin(Gm)에 대한 내성양상과 아미노 배당체 항생제 변경효소인 ANT(2") 및 APH(3') 유전자의 분포를 조사하였으며, spot hybridization(SPH)과 plasmid 및 전체 DNA를 Southern hybridization을 시행한 성적을 비교하였다. 재료 및 방법 : 91주의 Klebsiella를 사용하였으며, ANT(2")유전자에 대한 probe는 pFCT3103을 AvaⅠ으로 처리한 후 310bp 크기의 절편을, APH(3')Ⅰ유전자에 대한 probe는 Tn 903을 XhoⅠ과 HindⅢ로 처리한 후 520bp 크기의 절편을 사용하였다. 결과 : 91주 중 20주가 Km과 Gm에 내성을 나타내었으며, 서울에서 분리된 균주의 내성빈도가 29.3%로 대구(11.6%)보다 높았다. 변경효소 ANT(2") prode와 hybridization 양성을 나타낸 것이 13주, APH(3') probe와 hybridization 양성을 나타낸 것이 8주였으며, 2가지 probe 모두에 양성인 것이 4주였는데, APH(3') probe와 hybridization 양성을 나타낸 8주는 모두 서울에서 분리된 균주들이었다. 결론 : 항생제 변경효소의 유전자 probe를 이용하여 hybridization함으로써 단순한 plasmid 크기의 비교나 제한효소 절단 양상의 관찰로 확인하기 힘든 유전자 내용에 대한 조사를 하여 지역간의 항생제 내성의 차이를 증명할 수 있었다. Ninty-one strains of Klebsiella pneumoniae isolated from clinical specimens in Seoul, Taegu, and Pusan areas were evaluated for the resistance to kanamycin(Km) and gentamicin(Gm). Frequency of resistance to aminoglycoside antibiotics of strains isolated in Seoul(29.3%) was higher than those in Taegu(11.6%). Of all strains, 20 strains were resistant to Km and Gm, and harbored 1-4 plasmids ranged from 2.8 to 142 megadaltons (MDa). ANT(2") and APH(3') probes were used to detect aminoglycoside-modifying enzymes ANT(2") and APH (3') genes of these resistant strains. By spot-hybridization, 13 strains were hybridized with both probes. All strains hybridized with APH (3') probes were the Klebsiella pneumoniae strains isolated in Seoul, and 3 strains resistant to Km were hybridized with APH (3') probe. The sizes of plasmids hybridized with ANT(2") were variable and with APH(3') were 82MDa and 17MDa. Four strains harboring 82MDa and 17MDa plasmids were isolated from a hospital in Seoul. 82MDa plasmid of Klebsiella pneumoniae YKK103 was hybridized with both probes. Four strains were hybrdized with the ANT (2") or APH(3')probes in spot-hybridization, but not hybridized with plasmids and chromosomal DNA in Southern-hybridization.

      • 가청수중음에 의한 넙치의 행동에 관한 기초적 연구 : 1.육상수조 양식장내의 환경소음

        이유철,이창헌,최찬문,박용석,서두옥 제주대학교 해양연구소 1997 해양자원연구소연구보고 Vol.21 No.-

        A fundamental experiment was carried out to confirm the behaviour of Bastard halibut Paralichthys olivaceus to audible underwater sound in a breeding ground around the coast of Cheju Island. To find characteristics of breeding water tank and experiment water tank. ambient noise, undcrwater noise and feeding sound of fish were measured and analyzied respectively. The results of measurement are as follows: 1. The maximum sound pressure level of ambient noise in breeding water tank was 81dB. average maximum sound level of underwater noise was 81dB at 120Hz. 2. The maximum sound pressure level of ambient noise in experiment water tank was 76dB and underwater noise was 84.2dB at 130Hz. 3. The maximum sound pressure level of feeding sound was 85dB at 120Hz.

      • Shigella R Plasmid의 분자적 특성

        이유철,설성용,조동택,전도기,Lee, Yoo-Chul,Seol, Sung-Yong,Cho, Dong-Taek,Chun, Do-Ki 대한미생물학회 1987 大韓微生物學會誌 Vol.22 No.1

        Multiply resistant Shigella strains isolated in Taegu area were subjected for the characterization of R plasmids. All strains isolated in 1984 and 1985 were susceptible to gentamicin, amikacin, and cephalothin, and most strains were susceptible to kanamycin (Km) and rifampin by agar dilution antimicrobial susceptibility test. The resistance frequency of S. flexneri against ampicillin (Ap) was higher than that of S. sonnei. The strains resistant to sulfisomidine (Su) and trimethoprim (Tp) were found at higher frequency in S. sonnei than in S. flexneri. The most prevalent resistance pattern of S. flexneri was chloramphenicol (Cm) tetracycline (Tc) streptomycin (Sm) Ap, followed by the pattern of CmTcSmSuApTp, CmTcSmSuApTp nalidixic acid, and CmTcSmSuAp in the decreasing order. The antibiogram of CmTcSmSuTp was found to be the most frequent pattern in S. sonnei. The ratio of conjugal transfer of S. flexneri was 47% and 75% of S. sonnei. The average number of plasmid harboring in Shigella was 4 and the size of plasmid ranged 1.3 to 134 megadalton (Mdal). Most S. flexneri carried plasmids of 2 to 3 Mdal and S. sonnei carried those of 3 to 4 Mdal size. The sizes of conjugative plasmids ranged 40-90 Mdal. The incompatibility group (Inc) F II plasmids (54-59 Mdal) were most frequent and rare Inc B plasmids (60 Mdal) of isolates in 1979 and 1980 and Inc FI (87 Mdal) of 1983 isolates were able to be classified by the colony test with standard reference plasmids. The R plasmids of known Inc group were tested for the restriction endonuclease analysis. The pattern of plasmids digested by EcoRl were apparently different by the Inc group but there was no significant difference between species or by the resistance patterns. Nonconjugative plasmids and their phenotypes were identified by transformation test. The transformants were resistant to less than two drugs. Colicin producing transformants carried the Col plasmid of 3.7 or 3.9 Mdal size. $Ap^r$ plasmids derived from S. sonnei were found to be mobilized by transfer factor RT641 to E. coli #CS100. $Ap^r$ plasm ids of same size shared by S. flexneri, S. sonnei, and E. coli were digested with Pstl. All of them showed two restriction fragments of 2.8 kilobase(kb) and 0.7kb. Other plasmids ($Sm^r\;Su^r$) derived from S. flexneri, S. boydii, and S. sonnei were digested with Pstl and they showed same restriction fragment patterns of 3.1kb and 2.9kb. The plasmid profiles of three strains of S. sonnei producing colicin and showing same resistance pattern of CmTcSmSuApTpKm appeared to be similar. Restriction patterns by EcoRl and the behavior of plasmids in conjugation or transformation process were also similar between those plasmids. The restriction patterns were significantly different between the plasmids of Inc FI group and those of unclassified Inc group.

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