X선에 노출된 보리의 생장과 엽록소 측정

이원정(Won-Jeong Lee),이모권(Mo-Kwon Lee),이중록(Lee Jung Rok),김하늘(Kim Ha Neul),유세종(Se-Jong Yoo),이배원(Bae-Won Lee),정순철(Sun-Cheol Jeong) 대한방사선과학회(구 대한방사선기술학회) 2021 방사선기술과학 Vol.44 No.3

The purpose of this study is to measure of growth and chlorophyl in barley exposed by X-ray. Barley seed was soaked 24h duration in water, then was classified into two group; pre-seed germination group (Pre-G) or post-seed germination group (Post-G). Also, divided as control subgroup and experimental subgroup(10Gy, 20Gy, 30Gy) in each group. Experimental subgroups were exposed by X-ray using linear accelerator (Clinac IS, VERIAN, USA). Expose condition was 6 MV X-ray, SSD 100 cm, 18×10 cm, 600 MU/min. Length was measured every day for 10 days and 10th day for weight. Chlorophyl was analyzed using spectrophotometer(uv-1800, shimadzu, japan) in l0th day. Data analysis was performed using SPSS ver 22.0(Chicago, IL, USA), ANOVA test (Dunnett_T3) between control subgroup and experimental subgroup in group and Independent T-test between Pre-G and Post-G in subgroup. In Pre-G, length of barley was significantly difference between control and 30Gy in 4th day (4.3 vs. 1.5, p= 0.011). Length of 30Gy was statistical difference with control(10th day; 14.4 vs. 6.3, p < 0.01), and was not in 10Gy or 20Gy in all day. In experimental subgroup, length was shorter as increasing radiation dose. In Post-G, length of barley was not difference statistically between control and experimental subgroup in first day, but more difference between two subgroup with increasing duration after exposing. Length of experimental subgroup was shorter significantly compared with control in 10th day, and no significant difference between experimental subgroup. Density of chlorophyl was increasing with increasing radiation dose in Pre-G and Post-G. Chlorophyl density of control was lower than 30Gy; 0.26ppm in Pre-G, 0.29ppm in Post-G). Growth and chlorophyl of barley was effected by X-ray. It is expected to be used as basic data for future radiobiological research.

한국 노인의 일반촬영 이용량 및 피폭선량 : 2016년 고령환자데이터 기반

길종원(Jong-Won Gil),유세종(Se-Jong Yoo),이원정(Won-Jeong Lee) 대한방사선과학회(구 대한방사선기술학회) 2021 방사선기술과학 Vol.44 No.5

This study aims to provide basic data for elderly health insurance policy and medical radiation safety management by analyzing the general radiography usage and exposure dose of the elderly in Korea. The effective dose for each general radiography was calculated using the ALARA-GR program for 260 general radiography codes selected from ‘National Health Insurance Care Benefit Cost’. The usage of general radiography was analyzed in the 2016 elderly patient data of the Health Insurance Review and Assessment Service, and the effective dose for each general radiography was applied. The general radiography usage and exposure dose per person aged 65 years and over was 6.47 cases and 0.56 mSv. Females showed higher value than males as 7.15 cases and 0.66 mSv(p<.001). By age, those between 75 and 79 showed the highest number as 6.97 cases and 0.62 mSv(p<.001). Those who were supported by Medical Aid showed higher value than those who were insured by National Health Insurance as 8.82 cases and 0.76 mSv(p<.001). In addition, the ratio by radiography was in the order of Chest 20.85%, Knee Joint 15.58%, and L-spine 14.67%, and the exposure dose was L-spine 29.40%, Chest 15.82%, Abdomen 7.97%, and Entire Spine 7.20%. General radiography, which is widely used due to the high frequency of diseases in the elderly population should be taken into consideration when establishing health insurance policies. In addition, it is necessary to check whether the general radiography with high exposure dose is performed as a routine examination without considering medical necessity.

분진에 노출되었던 집단의 흉부 저선량 CT영상 소견

이원정(Won-Jeong Lee),선종률(Jong-Ryul Seon),안봉선(Bong-Seon Ahn),박영선(Young-Sun Park) 대한방사선과학회(구 대한방사선기술학회) 2011 방사선기술과학 Vol.34 No.4

분진에 노출된 집단의 흉부 디지털영상에서 진폐 소견에 따라 흉부 저선량 CT영상에서 발견된 소견을 비교 분석하였다. 2007년 4월부터 2008년 8월 사이 일개 진폐정밀건강진단기관에 내원한 진폐정밀건강진단 대상자 남자 328명에 대해 저선량 CT촬영을 실시하였고, 진폐 판독경험이 많은 1명의 영상의학과 전문의가 판독하였다. 흉부 디지털영상의 진폐 소견은 국제노동기구 흉부 영상 분류법(ILO, 2000)따라 아날로그 표준 사진을 참조하여 2명의 영상의학과 전문의가 합의 판독한 결과로부터 얻었고, 소음영의 병형에 따라 진폐 소견이 없는군(87명, 26.5%)과 있는군(241명, 73.5%)으로 분류하였다. 진폐 소견이 있는군에서 나이(60.9 vs. 65.0, p<0.001)와 분진노출기간(17.0 vs. 19.2, p=0.024)이 통계학적으로 유의하게 높았지만, 흡연력은 차이가 없었다. 전체 대상자 328명 중 245명(74.7%)이 저선량 CT영상에서 13 종류의 소견이 발견되었다. 진폐 소견이 없는군 보다 있는군에서 관상동맥 석회화 소견이 통계학적으로 의미 있게 높은 빈도를 보였고(25.3% vs. 36.9%, p=0.049), 벌집모양 소견도 높은 빈도를 보였다(1.2% vs. 6.2%, p=0.079). 하지만, 저선량 CT영상에서 진폐 소음영을 시사하는 작은 결절은 진폐 소견이 없는 군에서 더 높은 빈도를 보여 흉부 디지털영상이 민감도가 낮았다. 이상의 결과에서 분진 노출에 의한 진폐 소견이 저선량 CT영상의 관상동맥 석회화 소견과 유의한 관련성을 보였지만, 독립적인 위험요인임을 규명하기 위해서는 관상동맥 혈관 조영술을 이용한 전향적인 추가 연구가 필요할 것으로 사료된다. The purpose of this study was to compare the findings on the chest low-dose CT (LDCT) images between the negative and positive groups for pneumoconiosis in the group exposed to inorganic dust. From May 30, 2007 to August 31, 2008, total 328 subjects were examined by a LDCT. LDCT images were read by a chest radiologist who has much experience for reading of pneumoconiosis. All subjects were classified into two groups based on digital images after consensus reading of two radiologists according to the ILO 2000 guidelines; negative group (87, 26.5%) without pneumoconiosis and positive group (241, 73.5%). Statistical analysis was performed using a SPSS 14.0. There were significant differences in age (60.9 vs. 65.0, p<0.001), and in dust expose duration (17.0 vs. 19.2, p=0.024) between two groups, but no significant difference in smoking (p=0.784). Of the 328 subjects, 13 diagnosis were extracted from 245 subjects (74.7%). Coronary artery calcification (CAC) was significantly higher in positive group than that in negative group (36.9% vs. 25.3%, p=0.049). Honeycombing showed higher frequency in positive group than in negative group (6.2% vs. 1.2%, p=0.079). Pneumoconiosis findings caused by inorganic dusts exposure showed the significant relation with CAC on LDCT images. Future studies need to prove that pneumoconiosis finding is independent risk factor for CAC using a coronary artery angiography.

폐질환의 선별검사를 위한 저선량 전산화 단층촬영의 적용

이원정(Won-Jeong Lee),최병순(Byung-Soon Choi),박영선(Young-Sun Park),선종률( Jong-Ryul Seon),배석환(Seok-Hwan Bae) 대한방사선과학회(구 대한방사선기술학회) 2009 방사선기술과학 Vol.32 No.2

전산화 단층촬영은 폐질환의 정밀진단 방법으로 사용이 증가되고 있다. 통상적으로 시행되는 CT촬영은 조기 진단을 위한 선별검사로써는 높은 방사선 노출과 고비용, 조영제 사용으로 인한 부작용 등으로 적당하지않다. 영상의학분야에서 방사선을 이용한 CT촬영은 진단 능력이 우수한 반면 피폭선량 또한 매우 높아 선량 감축을 위한 노력이 절실하다. 그동안 많은 연구들에서 무증상기의 폐암 및 폐질환을 조기 발견하기 위한 선별검사로써 저선량 CT의 유용성에 대해 이루어져 왔고, 의미있는 결과를 보고하였다. 선량 감소에 많은 인자가 관여하고 있지만 조사선량(mAs)의 감소가 가장 많이 사용되고 있다. 이미 보고 된 많은 연구에서 저선량 CT는 폐질환을 조기 발견하기 위한 선별검사로써 임상에서 사용하기에 유용하지만, 일부 연구에서 조기 폐암을 예측할 수 있는 작은 결절을 발견하는데 낮은 민감도와 특이도를 보였고, 실제 생존율 증가에는 기여하지 못한 보고도 있었다. 따라서, 지금까지의 저선량 CT에 대한 연구결과를 토대로 다양한 위험에 노출된 집단을 대상으로 선량을 감소시키기 위한 연구가 계속적으로 이루어진다면, 향후 저선량 CT촬영은 폐암을 비롯한 폐질환의 조기진단방법으로써 통상적으로 사용되고 있는 표준 CT촬영을 충분히 대체할 수 있을 것으로 전망한다. As CT has been increasingly used as an accurate screening tool for lung disease, radiation dose becomes an important issue for both radiographers and patients. Many researches have been done for a low-dose CT as a screening tool for early detection of asymptomatic lung diseases. From those studies, it has been reported that chest dose rate from the low-dose CT is considerably lower than from standard CT. The patient dose is determined by scanning parameters such as kVp, mAs, pitch, scan time and the radiation risk of lung in screening examination may not be negligible. Herein, we suggest that Low-dose CT is useful as a screening tool in routine clinical practice on the basis of published articles, but further study is necessary because Low-dose CT has poor sensitivity and specificity for screening early stage of lung cancer according to the results of the studies. This article is to provide a brief overview of the screening examinations by Low-dose CT.

Relationship of Image Quality and Radiation Dose for Chest Radiography in the Medical Institutions for Pneumoconiosis

Won-Jeong Lee(이원정),Sung Jin Kim,Jai-Soung Park,Jong-Ryul Seon 대한직업환경의학회 2012 대한직업환경의학회 학술대회 논문집 Vol.2012 No.11

Scott변압기 전력계량 에러현상에 대한 고찰

박종일(Jong-il, Park),이원정(Won-jung, Lee) 대한전기학회 2020 대한전기학회 학술대회 논문집 Vol.2020 No.7

몬테카를로 시뮬레이션에 의한 납과 비스무트 흡수율 분석

김갑중,김낙상,유세종,이원정,김정호,홍성일,전민철,Kim, Gap-Jung,Kim, Nak-Sang,Yoo, Se-Jong,Lee, Won-Jeong,Kim, Jeong-Ho,Hong, Seong-Il,Jeon, Min-Cheol 한국방사선학회 2022 한국방사선학회 논문지 Vol.16 No.4

의료현장에서는 방사선으로부터 인체를 보호하기 위하여 납 앞치마를 사용한다. 하지만 납은 중금속으로 인체 및 환경에 유해성을 나타내고 있어 다양한 차폐체 개발이 진행되고 있다. 본 연구에서는 납과 원자번호가 비슷한 비스무트를 새로운 소재로 설정하고 같은 에너지 영역에서 두께에 따른 흡수율을 몬테카를로(Monte Carlo) 시뮬레이션을 통해 분석하였다. 납 차폐체 두께가 0.25 mm인 경우 비스무트 두께가 0.3 mm, 납 0.50 mm인 경우 비스무트 0.60 mm, 납 0.75 mm인 경우 비스무트 0.90 mm에서 유사한 경향성을 확인할 수 있었다. 따라서 차폐체의 소재로 납을 비스무트로 대체하여 사용하는 데는 무리가 없을 것으로 사료된다. In the medical field, lead aprons are used to protect the human body from radiation. However, lead is a heavy metal that is harmful to the human body and the environment, so various shield are being developed. In this study, bismuth, which has a similar atomic number to lead, was set as a new material and the absorption rate according to thickness in the same energy region was compared and evaluated through Monte Carlo simulation. The same tendency was confirmed when the thickness of the lead shield was 0.25 mm, the thickness of the bismuth was 0.3 mm, when the lead was 0.50 mm, the bismuth was 0.60 mm, and when the lead was 0.75 mm, the bismuth was 0.90 mm. Therefore, it is reasonable to replace lead with bismuth in the shield material.

단보 : 고혈압과 정상혈압쥐에서의 식이지방 변화에 따른 혈청과 간의 지질대사 동향

조성희(Sung Hee Cho),신응남(Eung Nam Shin),서미영(Mi Young Suh),이원정(Won Jong Lee) 대구가톨릭대학교 자연과학연구소 1991 응용과학연구논집 Vol.1 No.-

어유식이가 본태성고혈압쥐(SHR)혈압 및 지질대사에 미치는 영향 - 혈청지질상태를 중심으로 -

신응남(Eung-Nam Shin),배복선(Bok-Seon Bae),이원정(Won-Jong Lee),조성희(Sung-Hee Cho) 한국식품영양과학회 1989 한국식품영양과학회지 Vol.18 No.1

C_(20)이상의 ω₃ 다불포화지방산을 많이 함유한 어유가 본태성 고혈압쥐(SHR)의 혈압과 혈청 지질상태에 미치는 영향을 조사하기 위해 고등어유, 대두유, 쇠기름을 식이에 5% 함유시킨 분말식이를 각각 조제하여, 생후 4주된 SHR과 정상혈압 Wistar쥐 숫컷에게 8주간 섭취시켰다.<br/> Wistar종의 성장은 세 군 모두에서 8주간 지속적이었으며 고등어유군의 성장율이 5주 이후에는 다른 군보다 다소 높았다. SHR의 성장은 6주까지는 원만하였으나 그 후 거의 정지상태였고 식이지방군 간의 차이는 거의 없었다. 수축기혈압은 실험초기부터 SHR이 높아서 6주부터는 150㎜Hg이상의 고혈압을 나타내었다. 식이 8주의 혈압은 SHR에서는 고등어유군이 가장 낮았고, Wistar에서는 세 군 사이에 차이가 없었다. 심장과 신장무게가 SHR에서 컸으며, 현미경관찰에 의하여 SHR 심장조직 endo mysium과 신장조직의 urinary space 가 축소되었음을 볼 수 있었으나 식이에 따른 조직무게나 구조상 차이는 없었다.<br/> 고등어유는 Wistar종과 SHR 모두에게서 혈청 중성지방을 낮추는 효과가 있었고, SHR의 중성지방값이 Wistar종보다 대 체로 낮았다. 혈청 총 콜레스테롤과 HDL-콜레스테롤값은 식이군간에 차이는 없었으나 SHR의 HDL-콜레스테롤값이 Wistar종에서 보다 낮았다. 혈청지단백질 분획비를 보면 일반적으로 SHR이 VLDL이 높고 HDL이 낮았고, 고등어유군의 HDL₁HDL_(2+3) 비율이 타군 보다 낮았다. 세 식이지방의 주요 지방산이 혈청지질에 반영되어 혈청 인지질과 중성지질 구성지방산은 세 군이 각각 특색있는 지방산 구성 양상을 나타내었는데 대두유군의 C_(18;2)(ω_6)의 반영도가 제일 뚜렷하였으나 SHR 에서는 Wistar 종에서 보다 그 정도가 낮았고 고등어유의 C_(22:6)(ω₃)는 중성지방에서만 주로 관찰되었다. 이러한 지질 구성지방산의 차이가 혈청지질 패턴변화에 중요원인으로 사료된다. The present study was designed to examine tho effect of dietary fish oil on blood pressure and lipid status of serum. Weanling SHRs and normotensive Wistars were fed a diet containing 5%(w/w) mackerel oil(MO), soybean oil(SO) or beef tallow(BT) for 8 weeks. Growth rate was not significantly different among three dietary groups, but that of SHRs was silightly lower than that of Wistars. SHRs showed higher systolic blood pressure than Wistar rats from the beginning and become hypertensive (over 150㎜Hg) after 6 week s of feeding period. The MO group of SHRs showed the lowest blood pressure at the 8th week of feeding period but that of Wistars showed similar values with other groups. Tissue weights of liver, heart and kidney were not different amongdietary aroups in Wistars and SHRs. However, heart and kidney weights of SHRs were signigicantly higher than those of Wistars. Microscopic examination revealed that endomysium of heart tissue and urinary space of kindney were narrowed in SHRs. Serum total and HDL-cholesterol showed similar values among three different dietary fat groups but triglyceride levels were significantly low in MO groups. HDL-cholesterol levels of SHRs were lower than those of Wistars, as well as the fractions of total HDL, the sum of HDL and HDL₂,₃, while VLDL fractions were higher in SHRs. MO groups had the lower values of HDL₁ HDL₂,₃, ratio than SO and BT groups. Major dietary fatty acids were more or less incorporated into serum phospholipid and triglyceride, resulting in the characteristic fatty acid profile of each dietary group. Incorporation of C_(18:2)(ω_6) in SO groups were pronounced, but the degree of incorporation was lower in SHRs. In Mo groups, C_(22:6)(ω₃) levels were inreased in triglyceride. It is suggested that these changes in serum lipid fatty acid composition are related to the different patt erns of serum lipid by alteration of dietary fats.

고혈압과 정상혈압쥐에서의 식이지방변화에 따른 혈청과 간의 지질대사동향

조성희(Sang Hee Cho),신응남(Eung Nam Shin),서미영(Mi Young Sah),이원정(Won Jong Lee) 한국지질동맥경화학회 ( 구 한국지질학회 ) 1991 韓國脂質學會誌 Vol.1 No.1