동맥관개존증의 술후 심전도변화에 관한 임상적 연구

이신영,김근호,Lee, Sin-Yeong,Kim, Geun-Ho 대한흉부심장혈관외과학회 1986 Journal of Chest Surgery (J Chest Surg) Vol.19 No.1

At the Department of Thoracic and Cardiovascular Surgery, Hanyang university, from 1976 to 1984, 102 patients operated for isolated patent ductus arteriosus were studied. The correlation between the degree of left ventricular hypertrophy [LVH] and hemodynamic data, and postoperative changes of electrocardiographic findings were evaluated. The following results were obtained; [1] Of 102 patients with isolated patent ductus arteriosus, 78 patients [76.5%] were found to have LVH by EKG, preoperatively. [2] The patients with LVH had higher incidence of respiratory infection [79.4%] compared to patients without LVH. [3] Frequent physical findings in the patients with LVH were precordial bulging and P2 accentuation on auscultation. The typical continuous machinery murmur was not different in two group with or without LVH. [4] 66.1% of patients with LVH showed more than 56% of cardiothoracic ratio [CTR] on simple chest X-ray. 56.5% of patients without LVH showed less than 50% of CTR. [5] In the patients found to have LVH by EKG, the correlation between values of Svl+Rv6 and Qp/Qs in hemodynamic data was correlation coefficient 0.57 and between CTR and Qp/Qs was correlation coefficient 0.51. [6] In patent ductus arteriosus with LVH following surgery, the values of Svl+Rv6 was changed from preoperative 153.6$\pm$42.78% to 107.7$\pm$19.58% within 3 months and to 80.4$\pm$12.22%, which is within normal range of Svl+Rv6 on EKC, after 6 months.

산.학 활성화에 의한 학회의 비상(飛上)을 위한 소고(小考)

이신영,Lee, Sin-Yeong 한국미생물 · 생명공학회 2008 생물산업 Vol.21 No.4

The Relaxing Effect of α-Defensin 1 on the Adrenergic Responses of Rat Bladder

이신영,Don-Kyu Kim,Kyung Do Kim,명순철,Moo Yeol Lee 대한약리학회 2011 The Korean Journal of Physiology & Pharmacology Vol.15 No.3

Defensins, cysteine-rich cationic polypeptides released from neutrophils, are known to have powerful antimicrobial properties. In this study, we sacrificed 30 rats to investigate the effects of α-defensin 1 on detrusor muscle contractions in isolated rat bladder. From the experiments we found relaxing effects of α-defensin 1 on the contractions induced by phenylephrine (PE) but not by bethanechol (BCh) in the detrusor smooth muscles. To determine the mechanisms of the effects of α-defensin 1, the changes of effects on PE-induced contraction by α-defensin 1 pretreatment were observed after pretreatment of Rho kinase inhibitor (Y-27632), protein kinase C (PKC) inhibitor (Calphostin C), potent activator of PKC (PDBu; phorbol 12,13-dibutyrate), and NF-κB inhibitors (PDTC; pyrrolidinedithiocarbamate and sulfasalazine). The contractile responses of PE (10−9∼10−4 M) were significantly decreased in some concentrations of α-defensin 1 (5×10−9 and 5×10−8 M). When strips were pretreated with NF-κB inhibitors (PDTC and sulfasalazine; 10−7∼10−6 M), the relaxing responses by α-defensin 1 pretreatment were disappeared. The present study demonstrated that α-defensin 1 has relaxing effects on the contractions of rat detrusor muscles, through NF-κB pathway. Further studies in vivo are required to clarify whether α-defensin 1 might be clinically related with bladder dysfunction by inflammation process.

10 kg 이하의 활로4징증 환자에서 완전교정술에 관한 임상적 고찰

이신영,김창호,Lee, Sin-Yeong,Kim, Chang-Ho 대한흉부심장혈관외과학회 1991 Journal of Chest Surgery (J Chest Surg) Vol.24 No.6

The surgical management of symptomatic tetralogy of Fallot in infants is debatable. From November 1986 to August 1990, 21 infants under 10 kg of the body weight with tetralogy of Fallot underwent primary repair. Mean body weight was 8.6$\pm$1.40kg. All the patient were clubbing and there were cyanotic except for 1 patient. Transannular patch was laid down in 8 patients. Right ventricular outflow patch was used with Goretex but pericardial patch was utilized in 3 patients at the initial period of operation. Incidence of the complications following total correction of tetralogy of Fallot was more frequent in the patients placed with transannular patch compared to the patients with right ventricular outflow tract patch. Two deaths occurred in the 21 patients, Hospital mortality was 9.4%, but there were no operative deaths in the patients who transannular patch was laid down. Causes of deaths were low cardiac output.

Korean Americans’ Beliefs about Colorectal Cancer Screening

이신영,Eunice E. Lee 한국간호과학회 2013 Asian Nursing Research Vol.7 No.2

Purpose: The purpose of this study was to assess Korean Americans’ (KAs) health and cultural beliefs about colorectal cancer (CRC) and their CRC screening utilization in order to understand how health and cultural beliefs play a role in CRC screening utilization and why KAs have a low rate of CRC screening. Methods: Face-to-face, individual interviews with 26 Korean immigrants aged 50 and older were conducted in Korean. A semi-structured interview guide with open-ended questions was used to explore participants’ health and cultural beliefs about CRC and CRC screening. Recorded audio interviews were transcribed verbatim in Korean and coded using thematic analysis. Results: The themes that emerged from analyzing the individual interview data were: (a) valuing their families before themselves; (b) seeing a doctor only if they have symptoms; (c) believing that they would not get CRC; (d) balancing the will to stay healthy and fatalism; and (e) refusing health information. Conclusion: Results show the critical need for in-depth understanding of unique health and cultural beliefs about CRC screening in KAs. These beliefs could be useful for future intervention strategies to change health and cultural beliefs in order to increase CRC screening participation in KAs. Purpose: The purpose of this study was to assess Korean Americans’ (KAs) health and cultural beliefs about colorectal cancer (CRC) and their CRC screening utilization in order to understand how health and cultural beliefs play a role in CRC screening utilization and why KAs have a low rate of CRC screening. Methods: Face-to-face, individual interviews with 26 Korean immigrants aged 50 and older were conducted in Korean. A semi-structured interview guide with open-ended questions was used to explore participants’ health and cultural beliefs about CRC and CRC screening. Recorded audio interviews were transcribed verbatim in Korean and coded using thematic analysis. Results: The themes that emerged from analyzing the individual interview data were: (a) valuing their families before themselves; (b) seeing a doctor only if they have symptoms; (c) believing that they would not get CRC; (d) balancing the will to stay healthy and fatalism; and (e) refusing health information. Conclusion: Results show the critical need for in-depth understanding of unique health and cultural beliefs about CRC screening in KAs. These beliefs could be useful for future intervention strategies to change health and cultural beliefs in order to increase CRC screening participation in KAs.

컴퓨터 시뮬레이션에 의한 레토르트미반의 최적고온 살균조건

이신영,천병익,이상규,Lee, Shin-Young,Chun, Byong-Ik,Lee, Sang-Kyu 한국식품과학회 1985 한국식품과학회지 Vol.17 No.3

두께가 서로 다른(5${\sim}$24mm) 레토르트 미반에 대하여 여러온도(110-$150^{\circ}C$)에서 최적품질보유가 가능한 고온살균조건을 컴퓨터 simulation에 의하여 구하였다. 최적조건은 12D의 미생물학적 안전성을 유지할 때 최소의 c-값과 최대의 thiamine retention을 갖는 건에 의하여 선정하였다. 계산결과는 고온일수록 시료두께의 영향이 매우 중요함을 보이면서 미반고온살균의 우수한 음질보유는 두께 10mm이하에서 나타난다. Optimal quality retentions of cooked rice packed in retort pouch were simulated by computer using various thicknesses of retort pouch (5 to 24mm) and process temperatures (110 to $150^{\circ}C$). Optimal conditions were chosen by the minimal c-values and maximal thiamine retention when good bacteriological lethality (12D processing) was obtained. From the results of calculations, it were shown that the better quality retentions of high tharmal processing can be obtained below pouch thickness of l0mm and that the thickness of pouch is critical factor at higher processing temperature.

매독성 상행 대동맥류 수술치

이신영,강정호,지행옥,Lee, Sin-Yeong,Gang, Jeong-Ho,Ji, Haeng-Ok 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.1

The incidence of syphilitic aortic aneurysm was decreased now a day. We experienced a case of huge syphilitic ascending aortic aneurysm from just above portion of aortic annulus to about 1 cm below innominate artery without aortic insufficiency. Surgical correction was done by replacement of ascending aorta with woven Dacron graft under cardiopulmonary bypass. Postoperative course was uneventful and discharged 15 days after surgery with good condition.

대동맥폐동맥중격결손과 좌상공정맥을 합병한 VSD의 치험

이신영,지행옥,Lee, Sin-Yeong,Ji, Haeng-Ok 대한흉부심장혈관외과학회 1986 Journal of Chest Surgery (J Chest Surg) Vol.19 No.4

A case of ventricular septal defect associated with aorticopulmonary septal defect, left superior vena cava, and pulmonary hypertension in 6 years old boy is presented. Teflon patch closure of ventricular septal defect through transtricuspital procedure and division and suture closure of aorticopulmonary window performed under cardiopulmonary bypass with cardioplegia. The postoperative course was uneventful and discharged with good general condition.

방화관리실무 - 자동차재탐지설비의 유지관리

이신영,Lee, Sin-Yeong 한국화재보험협회 1991 防災와 保險 Vol.49 No.-

보리전분 수용액계의 리올로지적 연구

이신영,최준복,천병익,Lee, Shin-Young,Choi, Jun-Bok,Chun, Byong-Ik 한국식품과학회 1985 한국식품과학회지 Vol.17 No.3

쌀보리와 겉보리전분의 희석 및 농후호화용액에 대한 리올로지적 성질을 여러 점도계를 사용하여 연구하였다. 희석전분액(0.05${\sim}$0.3%)의 점도특성은 Huggins식에 따르는 고유점도 및 해수에 의하여 설명할 수 있었으며, 농후전분용액(1${\sim}$5%)의 리올로지적 거동은 농도의 증가에 따라 시간의존성과 의가소성의 성질이 현저히 강해지는 특징을 나타내었다. 지수법칙을 적용하여 구한 점조도지수 값은 지수함수식에 따르는 농도 및 은도의존성을 나타내었다. 한편 이들 결과는 리올로지적 성질이 품종차이에 따라 크게 달라지는 경향을 보였다. 쌀보리전분은 겉보리전분보다 더 큰 고유점도값을 나타내었으며, 틱소트로픽성질이 더 강한 것으로 나타난다. 아울러 점조도지수 값의 농도 및 온도의존성도 더 높은 경향이었다. 그러나 보리전분은 다른 전분에 비하여 비교적 낮은 농도의존성과 높은 온도의존성을 갖는 특징을 보였다. The rheological studies on dilute and concentrate solutions of naked and covered barley starches were carried out with various viscosimeters. The rheology of dilute solutions (0.05-0.3%) were characterized by intrinsic viscosity and related parameter according to Huggins equation. Also, the rheology of the solutions of higher concentrations (1-5%) were characterized by time dependent characteristics and pseudoplastic behaviors. The values of consistency index according to the power equation were exponen tially dependent upon concentration and temperature. The results showed that the rheological properties could differ greatly due to difference in varieties. The naked barley starch exhibited higher intrinsic viscosity, more thixotropic behavior and more dependence of consistency index on concentration and temperature than the covered barley starch.