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KLM(Keystroke-Level Model) 분석에 의한 PC통신 소프트웨어 과제별 탐색소요시간 평가
윤철호 선문대학교 1998 공과대학논문집 Vol.1 No.1
본 연구에서는 국내에서 보급되고 있는 전용 PC통신 소프트웨어 사용자 인터페이스의 사용편이 성을 향상시키기 위한 설계요인을 분석하고자 한다. 사용편이성을 평가하는 척도로서 절차적 복잡도 를 이용하였다. 절차적 복잡도를 기술하기 위해 KLM을 이용하였으며, 국내4대 전용 PC통신 소프트웨어 각각에 대해 분석하였다. 분석결과 국내에 보급되고 있는 전용 PC통신 소프트웨어는 과제별 탑색 소요시간에서 차이가 발견되었다. 이 차이는 PC 통신 소프트웨어 사용자 인터페이스의 설계요인 및 PC통신 서비스를 위한 데이터베이스 설계요인의 차이에서 비롯 되는 것으로 판단된다. This study reviews user interface design factors of pc communication softwares. Procedural complexity was utilized as an index to evaluate usability of those softwares. KLM(keystroke-level model) analysis is introduced to describe the procedural complexity of 4 major pc communication softwares. Statistically significant task search difference was observed during softwares and it is anticipated that this difference is caused by the difference of design factors in software user interface.
윤철호,Hye-Jin Park,Young-Woo Cho,김은진,이종덕,강기련,한재희,강다원 대한약리학회 2011 The Korean Journal of Physiology & Pharmacology Vol.15 No.6
The proliferation, migration, cytokine release, and contraction of airway smooth muscle cells are key events in the airway remodeling process that occur in lung disease such as asthma, chronic obstruction pulmonary disease, and cancer. These events can be modulated by a number of factors, including cigarette smoke extract (CSE). CSE-induced alterations in the viability, migration, and contractile abilities of normal human airway cells remain unclear. This study investigated the effect of CSE on cell viability, migration, tumor necrosis factor (TNF)-α secretion, and contraction in normal human bronchial smooth muscle cells (HBSMCs). Treatment of HBSMCs with 10% CSE induced cell death, and the death was accompanied by the generation of reactive oxygen species (ROS). CSE-induced cell death was reduced by N-acetyl-l-cysteine (NAC), an ROS scavenger. In addition, CSE reduced the migration ability of HBSMCs by 75%. The combination of NAC with CSE blocked the CSE-induced reduction of cell migration. However, CSE had no effect on TNF-α secretion and NF-κB activation. CSE induced an increase in intracellular Ca2+ concentration in 64% of HBSMCs. CSE reduced the contractile ability of HBSMCs, and the ability was enhanced by NAC treatment. These results demonstrate that CSE treatment induces cell death and reduces migration and contraction by increasing ROS generation in normal HBSMCs. These results suggest that CSE may induce airway change through cell death and reduction in migration and contraction of normal HBSMCs.