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      • $CO_2$ 레이저를 이용한 성인 후두유두종의 치료

        오장근,윤준식,이상준,정필상,Oh, Jang-Keun,Yoon, Jun-Sik,Lee, Sang-Joon,Chung, Phil-Sang 대한기관식도과학회 2007 大韓氣管食道科學會誌 Vol.13 No.2

        Background and Objective : Laryngeal Papillomatosis (LP) is the most common benign neoplasm of the larynx, but it tend to recur and it makes eradicating difficult. Meticulous $CO_2$ laser excision has been the most effective treatment to date. This article analyzes the clinical feature and therapeutic results of 42 LP patients who were undergone $CO_2$ laser excision. Methods : Forty two patients with recurrent LP were treated with $CO_2$ laser. And their medical records were reviewed retrospectively. Demographics, chief complaints at onset, initial distribution of papillomas, number of operations performed on each patient, and current results were evaluated. Results : Male in their twenties and forties are dominant in number in patient number. Most common site was anterior one thirds (69%) of glottis area (86%). LP recurred in 17 cases (40%), and in 4 cases, the lesion extended over the original margin. Patients were undergone surgery $1.62{\pm}0.87$ times, $2.53{\pm}0.72$ in recurred cases. Mean relapsing time was 6 momths (from 1momth to 8years). Ant. laryngeal web occurred in 2 cases (4.8%) and 1 case was combined with squamous cell carcinoma. Conclusion : Meticulously performed $CO_2$ laser excision can achieve significant voice and airway improvement and clinical cures. The $CO_2$ laser through microdirect laryngoscopy allows more precise and bloodless removal of papillomas.

      • KCI등재

        김치의 숙성 및 발효중 오염지표미생물과 유산균의 변화-제1보

        김종규,윤준식,Kim, Jong-Gyu,Yoon, Joon-Sik 한국환경보건학회 2005 한국환경보건학회지 Vol.31 No.1

        This study was undertaken to investigate the changes of index microorganisms and lactic acid bacteria of traditional Korean fermented vegetables (kimchi) during the ripening and fermentation period. A type of kimchi, baechoo-kimchi, was prepared and stored at $10^{\circ}C$ for 8 days. The numbers of the total aerobic bacteria, psychrotrophilic bacteria, coliform bacteria, and Escherichia coli in the kimchi and also in raw materials of the kimchi (Chinese cabbage, green onion, ginger, garlic, and red pepper) were counted using appropriate media. The highest number of aerobic bacteria was detected from ginger, then red pepper, then garlic, then Chinese cabbage, and lowest number from green onion. The highest number of psychrotrophilic bacteria was detected from red pepper, then Chinese cabbage, then garlic, then ginger, and the lowest number from green onion. Coliforms and E. coli were not detected from all of the raw materials of kimchi. Total aerobic bacteria and lactic acid bacteria of the kimchi showed gradually increasing during ripening and fermentation. The number of psychrotrophilic bacteria showed a similar level in the kimchi. Coliform bacteria were detected at the 3rd, 4th, and 5th day of the kimchi fermentation period, although they were not detected from the raw materials of the kimchi. However, the bacteria were not detected in the kimchi after 6 days. E. coli was not detected in all kimchi samples. The pH value of the kimchi gradually decreased, and acidity increased over fermentation period. This study indicates that there was contamination of coliform bacteria during the process of kimchi preparation, and lactic acid bacteria proliferated in the kimchi during fermentation inhibited the growth of coliforms. More research is needed to evaluate the inhibitory effects of each raw materials of kimchi.

      • KCI등재후보

        IT Governance의 전략적 가치와 도입 저해 요인에 관한 연구

        임종윤 ( Jong Yoon Lim ),정성현 ( Sung Yun Jung ),윤준식 ( Joon Sik Yoon ) LGCNS 엔트루정보기술연구소 2007 Entrue Journal of Information Technology Vol.6 No.2

        본 연구는 IT Governance의 전략적 가치와 도입 저해 요인에 관한 연구이다. 최근 정보기술의 급속한 진전과 함께 IT를 얼마나 효과적으로 기업 경영에 활용할 것인지가 경영혁신의 관건이 되고 있다. 이에 따라 IT를 경영전략과 연계하여 유효하게 활용할 수 있는 기업 내부의 메커니즘을 어떻게 구축할 것인지가 하나의 이슈로 떠오르고 있다. 또한 IT를 어떻게 효과적으로 관리하여 각종 컴플라이언스(The Sarbanes - Oxley Act, Basel II 등)를 포함한 IT로부터 야기되는 경영상의 위험을 관리할 수 있으며, 기업 IT 자산을 효과적으로 관리하여 경영 효율을 극대화시킬 수 있는가에 대한 노력이 선택이 아닌 기업 생존과 직결되는 필수 활동으로 부각되고 있는 것이다. 반면, 국내에서는 아직 IT Governance의 전략적 필요성에 대한 인식 확산이 더디고 도입이 늦어지고 있는 실정이다. 본 연구에서는 우선, 주요 IT Governance 연구기관과 IT 컨설팅 전문가 그룹에서 제시한 IT Governance의 개념과 전략적 가치, 시장 현황 등을 알아보고 IT Governance의 전략적 효용가치 대비 확산속도가 더딘 점에 초점을 맞추어 IT Governance의 도입 저해요인을 알아보고자 하였다. This study is intended to show how strategically important IT Governance is and what hinders its introduction to the Korean firms. Recently, with the rapid development of information technology, finding out more efficient way to apply IT emerged as a critical issue in the context of management innovation. Although the importance of IT application has been emphasized since the 1980s, how to build the internal mechanism supporting the efficient usage of IT inside of the firm in the respect of management strategy became an inportant question only lately. On the contrary, in the Korean society, people`s recognition on the strategic importance of IT Governance has been spread out rather slowly. In this research, we performed the following two tasks. First, we surveyed the concept of IT Governance and its strategic value and marketability that the major research institutes and experts have developed so far. Second, we at-tempted to figure out what made the Korean firms hesitate to introduce IT Governance to their real management, depite its well-understood strategic usefulness.

      • ALA 및 ALA-Methylester의 투여에 따른 종양조직 및 정상조직에의 분포양상에 대한 연구

        정필상(Phil-Sang),정상운(Sang Oun Jung),안진철(Jin Chul Ahn),이상준(Sang Joon Lee),윤준식(Jun Sik Yoon) 대한두경부종양학회 2003 대한두경부 종양학회지 Vol.19 No.1

        Objectives: In this report, we confirmed the distributed pattern of ALA and ALA-methylester in normal and tumor-bearing region. Materials and Methods: ALA and ALA-methylester were administered to nude mouse by intratumoral, subcutaneous and intravenous injection. After injection, the fluorescence in normal and tumor region was measured by LESA (laser electronic spectrum analyzer). Results: The tumor-specificity of ALA and ALA-methylester was shown in the case of intratumoral injection. In all case, the fluorescence caused by ALA and ALA-methylester was maximally increased in 2 hours after injection. Then while the fluorescence level was rapidly decreased to control level in normal region, it was still remained in tumor region. Conclusion: According to this result, The intratumoral injection was more efficient administration method for PDT/PDD than subcutaneous and intravenous injection.

      • SCOPUSKCI등재

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