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      • SCOPUSKCI등재
      • SCOPUSKCI등재

        심근경색 유발견에서 마취가 심초음파에 미치는 영향

        윤정희,성재기,Yoon, Jung-hee,Sung, Jai-ki 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.3

        The present study was performed to evaluate the effects of xylazine and tiletamine + zolazepam on echocardiograms before and after experimental myocardial infarctions in clinically normal dogs taken preliminary examinations related to cardiac function. The results are as follows. With xylazine administration, left ventricle end-diastolic dimension, left ventricle end-systolic dimension, left atrium/aorta, ejection time and velocity of circumferential fiber shortening increased and mitral valve CD slope, % delta D decreased(p<0.01). In tiletamine+zolazepam administered group, interventricular septum amplitude(p<0.01), mitral valve DE slope(p<0.05) and ejection time(p<0.01) decreased and left atrium/aorta, ejection time also decreased compared with xylazine group(p<0.01). In 48 hours after experimental myocardial infarction group, anterior aortic wall amplitude decreased compared with control, xylazine, tiletamine + zolazepam group, respectively(p<0.01). Posterior aortic wall amplitude decreased compared with control(p<0.01). Left ventricle end systolic dimension increased compared with control and tiletamine + zolazepam group, respectively(p<0.01). Left ventricular posterior wall end systolic dimension decreased compared with control(p<0.01). Left ventricular posterior wall amplitude decreased compared with control and tiletamine+zolazepam group(p<0.01). Left atrium/aorta decreased compared with xylazine group(p<0.01). % thickening left ventricular posterior wall decreased compared with control(p<0.05). % delta D decreased compared with control and tiletamine+zolazepam group(p<0.01). Ejection time decreased compared with xylazine(p<0.01). Velocity of circumferential fiber shortening increased compared with control and tiletamine + zolazepam group(p<0.01). With xylazine administration 48 hours after experimental myocardial infarction, anterior aortic wall amplitude, posterior aortic wall amplitude decreased compared with control(p<0.01). Left ventricle end-diastolic dimension increased compared with control(p<0.01). Left ventricle end-systolic dimension increased compared with control and tiletamine + zolazepam group, respectively(p<0.01). Left ventricular posterior wall end-systolic dimension and left ventricular posterior wall end-diastolic dimension decreased compared with control(p<0.01). Left atrium/aorta decreased compared with xylazine group(p<0.01). % thickening left ventricular posterior. wall(p<0.05) and % delta D(p<0.01) decreased compared with control. Velocity of circumferential fiber shortening increased compared with tiletamine + zolazepam group(p<0.01). With tiletamine + zolazepam administration 48 hours after experimental myocardial infarction, anterior aortic wall amplitude decreased compared with control, xylazine and tiletamine+zolazepam group, respectively(p<0.01). Posterior aortic wall amplitude decreased compared with control(p<0.01). Left ventricle end-systolic dimension increased compared with control and tiletamine+zolazepam group(p<0.01). Left ventricular posterior wall end-systolic dimension, left ventricular posterior wall end-diastolic dimension and interventricular septum amplitude decreased compared with control(p<0.01). Left atrium/aorta decreased compared with xylazine group(p<0.01). % delta D decreased compared with control and tiletamine + zolazepam group(p<0.01). Ejection time decreased compared with xylazine group and velocity of circumferential fiber shortening increased compared withtiletamine+zolazepam group(p<0.01). Conclusively, echocardiography was proved to be a useful, diagnostic, non-invasive and simple method for establishing the diagnosis of myocardial infarction and evaluating the effects of drug on cardiac function before and after myocardial infarction.

      • SCOPUSKCI등재

        화학적 보정약이 정상견의 도플러 심초음파에 미치는 영향

        윤정희,Yoon, Jung-hee 대한수의학회 1998 大韓獸醫學會誌 Vol.38 No.2

        Intracardiac velocities were determined and the wave-forms described for 4 flow areas of the normal canine heart following administration of chemical restraint drugs including xylazine HCl, ketamine HCl, and thiopental sodium using pulsed wave Doppler echocardiography. The result was that xylazine HCl and thiopental sodium reduced intracardiac flow velocities through mitral, tricuspid, aortic and pulmonary valves. It is also thought that precautions are required before using these drugs. Patterns of wave-forms had no changes between control and treatment groups. Doppler echocardiography allows the clinician to determine flow velocities across the different valves and within the various chambers of the heart. It is shown that establishing normal values and those related to chemical restraint administrations and knowing what influences them should allow the clinician to non-invasively diagnose a variety of pathological cardiac conditions.

      • KCI등재후보

        다문화 가정 영유아의 스마트 기기 사용실태 및 어머니 인식

        윤정희(Jung-Hee, Yoon),이하원(Ha-Won, Lee) 한국다문화복지학회 2020 복지와 문화다양성연구 Vol.2 No.1

        본 연구는 다문화 가정 영유아의 스마트 기기 사용실태 및 어머니의 인식을 조사하는 것을 목적으로 한다. 이에 다문화 가정이 비교적 많이 분포되어 있는 충남 및 경기도에 위치한 다문화 가정 어머니 총 108명을 대상으로 설문지 조사를 실시하였다. 설문지는 이원석, 서영화(2012)의 ‘유아와 부모의 스마트 사용실태’와 강연주(2014)의 ‘유아의 스마트 사용실태와 어머니 인식 척도’를 본 연구에 맞게 수정 보완하여 사용하였다. 수집된 자료는 SPSS 21.0을 사용하여 χ² 검증을 실시하였다. 결과는 첫째, 다문화 가정 영유아의 스마트 기기 첫 사용 시기는 13개월~24개월, 1회 사용시간은 20분 이하이며 매일 사용한다고 응답한 경우가 가장 많았다. 월평균 소득이 낮을수록 스마트 기기 사용시간이 높게 나타났고 사용법 및 사용결정은 어머니에게 의존하면서 함께 하는 것으로 나타났다. 또한, 재미와 학습적 요소를 위하여 스마트 기기를 사용하며 규칙을 정하고 사용한다고 응답한 경우가 가장 많았다. 둘째, 다문화 가정 영유아의 스마트 기기 사용에 대한 어머니의 인식은 스마트 기기의 필요성 유무에 유의한 차이가 없었으나 사용할 때는 읽기, 쓰기, 셈하기 등 교육적 기능에 목적을 두고 사용한다고 하였다. This study aims to investigate the use of smart devices by children from multicultural families and their mothers awareness. The survey was conducted on a total of 108 mothers from multicultural families in South Chungcheong Province and Gyeonggi Province, where multicultural families are relatively distributed. The questionnaire was supplemented by modifying ‘Smart Use Status of Infants and Parents’ from Lee Won-seok and Seo Young-hwa (2012) and ‘Mother Recognition Scale of Child Smart Use’ from Kang Yeon-ju (2014) for this study. The collected data were χ² validated using SPSS 21.0. The results were first, when children from multicultural families first use a smart device for 13 months to 24 months, and once use time is 20 minutes or less, and they said they use it every day. The lower the average monthly income, the higher the time spent using smart devices, and the more usage and decisions of use were found to be shared by relying on mothers. In addition, most respondents said that they use it for fun and learning elements and set rules and use them. Second, although there was no significant difference in the need for smart devices for multicultural children, the purpose of using them was to learn reading, writing, and counting.

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        5% Imiquimod 크림의 피부과 임상에서의 치료적 사용 경험

        윤정희 ( Jung Hee Yoon ),최재은 ( Jae Eun Choi ),안효현 ( Hyo Hyun Ahn ),계영철 ( Young Chul Kye ),서수홍 ( Soo Hong Seo ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.11

        Background: Imiquimod is an immune response modifier that shows antiproliferative and antiviral characteristics through synthesis of multiple cytokines. Although it was originally approved by the Food and Drug Administration for the treatment of anogenital warts, it has also been successfully used to treat various skin conditions. Objective: The aim of this study was to evaluate the current usage of 5% imiquimod cream for the treatment of various skin conditions in dermatologic clinics. Methods: We reviewed the records of 270 patients with various skin conditions who were treated with 5% imiquimod cream. Data was collected through medical records, clinical photographs, and biopsy specimens. Results: Besides anogenital warts, 5% imiquimod cream has been prescribed in more than 20 skin conditions. The most common skin disease was verruca vulgaris. Others, in order of prevalence, were molluscum contagiosum, actinic keratosis, condyloma accuminatum, and verruca plana. Among the 270 patients who were treated with 5% imiquimod cream, more than two-thirds showed clinical response, but only 26 patients (9.7%) achieved clinical complete remission with median clearing time of 7.3 weeks. While applying 5% imiquimod cream, 82 patients (30.4%) experienced local side effects that were generally mild and generally well-tolerated. The most common side effect was erythema and the others, in order of prevalence, were oozing, itching sensation, burning sensation, scabbing, erosion and pain. No systemic side effects were found. Conclusion: Although 5% imiquimod cream is licensed in Korea only for treatment of adult anogenital warts, other skin diseases such as verruca vulgaris are more commonly the treatment target in dermatologic clinics. As the reported therapeutic effects are various, more clinical studies are required to assess the safety and efficacy of imiquimod for the treatment of various skin conditions. (Korean J Dermatol 2011;49(11):993∼1001)

      • KCI등재
      • SCOPUSKCI등재

        경피적 바늘흡입생검 시술 후 피하로 파종된 간세포양 가슴샘암

        윤정희 ( Jung Hee Yoon ),서수홍 ( Soo Hong Seo ),계영철 ( Young Chul Kye ),안효현 ( Hyo Hyun Ahn ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.12

        Percutaneous needle aspiration biopsy is a reliable and useful procedure for diagnosing tumor with a low rate of complications and high diagnostic reliability. Subcutaneous malignant seeding of the needle tract is a well-known complication of percutaneous needle aspiration biopsy. Implantation metastases of the abdominal and chest walls have been reported after puncturing the tumor lesions of the liver, kidney, adrenal gland, lung and pleura. We report here on a case of subcutaneous seeding of hepatoid thymic carcinoma on the right upper back after a percutaneous needle aspiration biopsy. (Korean J Dermatol 2010;48(12):1104∼1107)

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