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백서의 일차배양 간세포에서 Plasminogen Activator와 Plasminogen Activator Inhibitor의 표피 성장인자 의존적 발현에 관한 연구
윤완희(Wan-Hee Yoon),최정훈(Jeong-Hun Choi),정연주(Yeon-Joo Jung),이병학(Byung-Hak Lee),김태동(Tae-Dong Kim),송인상(In-Sang Song),배진선(Jin-Sun Bae),임규(Kyu Lim),황병두(Byung-Doo Hwang) 대한외과학회 2001 Annals of Surgical Treatment and Research Vol.61 No.3
강민규 ( Min Kyu Kang ),윤완희 ( Wan Hee Yoon ),김인구 ( In Koo Kim ),손기섭 ( Ki Sub Son ) 대한외상학회 1988 大韓外傷學會誌 Vol.1 No.2
As a mean of transportation was developed and traffic volume was increased, the frequency of traffic accidents was increased and its scale became larger. The damage of property and loss of lives were enormous and death of traffic accidents became a main cause of death in a civilized community. The authors aurhors 493 cases of traffic accident treated at Chungam National University Hospital from January 1987 to December 1987, and the results were as follows: I) The age distribution was most prevalent between 25 and 44 years(45.6%), and the ratio of male to female was 2.8: I. 2) The most predominant monthly distribution was September(12.0%), and the least was February(5.7%). 3) Of 493 cases, 212 cases(43.0%) were associated with Orthopedic Surgery, Neurosurgery and General Surgery were 40.9 % and 7.9 % respectively. 4) In injury mechanism, motor vehicle accident was highest in incidence(36.9 %) and similar with pedestrian accident(36.1 %). 5) Most frequently injured body region was head and neck(64.9 %), and then extremity and pelvis was 43.3%, and abdomen was 7.5%. 6) The injured organs in 37 cases of abdominal injuries in order of frequency were sple-en(16.2%), small bowel(l6.2%), and liver(13.5%). 7) In elapsed time from arrival to death. 83.3% was died within first 24 hours and 66.7% was died within first 5 hours. 8) In mortality rate according to department, Neurosurgery was 55.6 % and General Surgery was 12.9%. The overall mortality rate was 11.0%. 9) Using a cutoff score of 6 or less, the Modified CRAMS scale identified the 15.2% 01 the trauma population which were critically ill as demonstrated by a 68.0 % mortality rate compared to a 0.7% overall mortality of those with a score of 7 or greater.
국소진행된 직장암에서의 수술전 방사선치료 단독군과 방사선치료와 항암제 병용치료군의 치료성적
김재성(Jae Sung Kim),박승호(Seoung Ho Park),조문준(Moon June Cho),윤완희(Wan Hee Yoon),배진선(Jin Sun Bae),정현용(Hyun Yong Jeong),송규상(Kyu Sang Song) 대한방사선종양학회 1995 Radiation Oncology Journal Vol.13 No.1
Purpose : to assess the efficacy and toxicity of the preoperative radiotherapy with or without chemotherapy in locally advanced rectal cancer. Methods : Forty three patients (clinically diagnosed stages above or equal to Astler-Coller stage B2 without distant metastasis) were assigned to preoperative radiotherapy alone arm (n=16) or combined preoperative radiotherapy and chemotherapy arm (n=27). Preoperative radiotherapy of 4500 cGy to whole pelvis +/- 540 cGy boost to primary site and concurrent chemotherapy of 2 cycles of 5-FU (500mg/m²) and leucovorin (20mg/m²) were used. fifteen patients of preoperative radiotherapy alone arm and 19 of combined arm received surgical resection after preoperative treatment. Results : During the preoperative treatment, no significant complication was developed in both groups. Pathologic results were as follows; complete remission 1, B1 1, B2 6, C1 2, C2 5 in preoperative radiotherapy alone arm and complete remission 2, B1 8, B2 4, C2 3, D 2 in combined arm. Postoperative complications were delayed perineal wound healing in three patients, intestinal obstruction in three patients (one managed by conservative medical treatment, two by surgical treatment). conclusion : The combined preoperative radiotherapy and chemotherapy arm was more affective in pathological response and lymph node negativity rate than the preoperative radiotherapy alone arm. Both the preoperative radiotherapy alone arm and the combined arm were generally well tolerated and did not result in an increased postoperative morbidity.
교통사고환자 1046예에 대한 분석 및 Modified CRAMS Scale
윤완희,장일성,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2
We retrospectively evaluated the nature, distribution, and pattern of the traffic accidents in 1046 cases of traffic accidents transported to chungnam National University Hospital from Jan. 1987 Dec. 1988. We also evaluated the ability of the CRAMS Scale to predict injury severity and mortality, and the results were as follows: 1. The age distribution was most prevalent between 25-44 years(44.6%), the ratio of male to female was 2.9:1, and the ratio of male of female of the children and old age group was 1.6:1. 2. There was no significant difference in seasonal distribution. 3. Of 1046 cases, 39.8% was associated with Orthopedic Surgery, Neurosurgery, Plastic Surgery, and Genera Surgery were 38.8%, 20.3%, and 10.0% respectively. 4. In injury mechanism, motor vehicle accident was highest in incidence(50.7%), pedestrian accident, motorcycle accident, and bicycle accident were 23.4%, 18.6%, and 7.3% respectively. 5. The most frequently injured body region was head and neck(65.6%), and then extremity and pelvis was 37.3%, and abdomen was 10.9%. 6. Traffic accident developed in urban area was 1.4 times more frequent than rural area. 7. In elapsed time from arrival to death, 77.6% was died within first 24 hours and 33.6% was died at scene or less than 1 hour. 8. The overall mortality rate was 11.9% and in mortality rate according to department, Neurosurgery was 52.8%, Chest Surgery was 20.8%, and General Surgery was 13.6%. 9. Using a cuttoff score 7 or less, the Modified CRAMS scale identified the 16.6% of the traffic accident population which were critically ill as demonstrated by a 67.2% mortality rte compared to a 0.9% mortality of those with score of 8 or greater.