인슐린의 종류와 작용

여윤정 사단법인 한국당뇨협회 1997 당뇨 Vol.91 No.-

원내 Alcohol류 소독제의 살균력 및 안정성 비교

박숙영,여윤정,공경희 한국병원약사회 2006 병원약사회지 Vol.23 No.2

The purpose of this experiment is to examine antimicrobial effectiveness and stability of the 70% isopropyl alcohol (IPA) and 80% ethanol (ETOH). The experimental disinfectants are 70% IPA, 80% ETOH, 0.5% chlorhexidine gluconate, 0.5% chlorhexidine gluconate in 80% ETOH, 0.5% chlorhexidine gluconate in 70% IPA. The experimental type of culture strain is same for the antimicrobial effectiveness test in USP(= Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Aspergillus niger), and modified antimicrobial effectiveness test is adopted for disinfectants. The method used in this experiment is to maintain the antimicrobial effectiveness and stability for 0,7,14,21,28 days in the condition of open disinfectants bottles. Five culture strains of 0.1 ml are exposed to disinfectants of 5 ml for 15, 30 seconds, and 1, 5, 10, 15 minutes. After that, exposed 5 culture strains are inoculated with TSA (Trypticase soy agar) and SDA (Sabouraud dextroseagar). The result of antimicrobial effectiveness test shows the counts of cultured colony. 5 culture strains are sterilized within 15 seconds for 80% ETOH, 0.5% chlorhexidine gluconate in 80% ETOH. Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans are sterilized within 15 seconds for 70% IPA, 0.5% chlorhexidine gluconate in 70% IPA, but Aspergillus niger is sterilized after 5 minutes for 70% IPA, 0.5% chlorhexidine gluconate in 70% IPA. In the perspective of stability, the antimicrobial effectiveness shows similar result when adjusting the test period from 0,7,14,21 to 28 days. In conclusion, 80% ETOH is superior to 70% IPA in the bactericidal activity.

암환자의 약물요법에 대한 전반적인 이해도와 암성통증관리의 만족도 조사

지정숙,이소현,여윤정,공경희 한국병원약사회 2005 병원약사회지 Vol.22 No.3

The purpose of this study was to evaluate patient's awareness about chemotherapy and the satisfaction about cancer pain management and to research the actual condition. This study was conducted through questionnaire of fifty outpatients and inpatients who received chemotherapy for one month from September to October 2003. As a result, only one patient was made a diagnosis as cancer by early medical examination, the rest of patients was diagnosed as cancer by subjective symptoms. 46% of the patients had positive thinking about alternative therapies and 36% of the patients answered used alternative therapies. Nobody knew drug interaction and side effects. Although patients took a pain management medicine, 20% of the patients experienced moderate pain. 78% of the patients was interfered with general activity, mood, walking, work, relationships and sleep despite use of analgesics. 20% of the patients took a pain management medicine at their discretion. The reason of it was fear about side effects and addiction. 74% of the patients answered satisfaction about pain management. The reason for satisfaction was that the pain was relieved after taking a pain management medicine. In conclusion, the research show that it is important to educate both patients and their family members about drug interaction information of alternative therapies and chemotherapy, and to correct patients false belief. To improve satisfaction of pain management and quality of life in cancer patients, we should educate patient about method of taking pain management medicine and misconceptions about opioids and analgesics.

Ondansetron과 Granisetron의 약물사용평가

이현주,신양희,허윤희,여윤정,김보영,조송자 한국병원약사회 1999 병원약사회지 Vol.16 No.3

An evaluation of ondansetron and granisetron use in hospitalized patients was performed in Korea University Medical Center Anam Hospital. Criteria for the evaluation of ondansetron use established by American Society Hospital Pharmacy and the evaluation of granisetron use partially modified from ondansetron's criteria were used in order to evaluate the appropriateness, effectiveness and safety of ondansetron and granisetron therapy. The charts of 119 patients who received ondansetron and 110 patients who received granisetron were retrospectively reviewed from Jan.1, 1998 to July 30, 1998. 59(50%) of the 119 ondansetron patients and 90(82%) of the 110 granisetron patients received their antiemetics appropriately based in the emetic potential of their antineoplastic drug regimen. Only 46(39%) of the ondansetron group and 14(13%) of the granisetron group met the criterion for appropriate dosage. 'Complete responses' of ondansetron and granisetron use evaluations, defined as no vomiting and no more than two episodes of nausea including no more than two p.r.n. doses of antiemetics, were observed in 108(91%) and 106(96%) in the outcome analysis, respectively. 'Major responses', defined as no more than two episodes of vomiting and more than two episodes of nausea, were observed in 11(9%) of the ondansetron group and 4(4%) of the granisetron group. Adverse reactions including headache, diarrhea, constipation, sedation etc. were reported by 22(18%) of the ondansetron group and 5(%) of the granisetron group. Ondansetron and granisetron use met all criteria except appropriate dosage and appropriate indication based on the antineoplastic drug regimen especially in the ondansetron group. Improved education of pharmacists and physicians about the use of ondansetron and granisetron would help to ensure proper prescribing.

고로슬래그 및 플라이애쉬를 혼입한 폴리머 시멘트 모르타르의 플로우 특성

조영국 ( Jo Young Kug ),여윤정 ( Yeo Yun Jeong ) 한국구조물진단유지관리공학회 2017 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.21 No.1

In general, polymer cement mortars that is made from organic polymer dispersion and cement have good workability compared with ordinary cement due to ball-bearing acting of polymer particles in cement mortar. The purpose of this study is to evaluate the workability of cement mortar according to adding of admixtures such as polymer dispersions, blast-furnace slag and fly ash. From the test results, the flow of polymer-modified mortars is increased with increasing polymer-cement ratio, and also is a little improved according to adding of fly ash compared to blast-furnace slag.

Pharmacological Interventions on Surgical Intensive Care Units Initiated by Pharmacists

Joohyun Lee,Eun-young Lee,여윤정,Yang-soon Oh,Sung-Soo Hong,이재명 대한외상중환자외과학회 2021 Journal of Acute Care Surgery Vol.11 No.1

Purpose: The severity of a patient’s medical condition, changing pharmacodynamics andpharmacokinetics, and variability in medication highlight the importance of pharmacologicalintervention by intensive care unit (ICU) specialized pharmacists. Methods: Retrospective observations of ICU interventions (omission, changes in medicine, sideeffects, changes in administration route and dosage, redundancy, and nutritional care) performedbetween April 2017 and March 2018, determined by an interdisciplinary team (including aspecialized ICU pharmacist and a surgical intensivist) on their surgical ICU round, were analyzed. Medicinal prescriptions were screened weekly during the surgical ICU round, and interventions weremade if any corrections were necessary. Two days later another team including a surgical intensivist,a pharmacist, and a nutritionist evaluated the patients’ nutritional status (performed weekly). Results: In the 23-bed ICU, the average number of patients whose prescriptions were examinedwas 22.38 per surgical round. There were 382 interventions made over 1 year, which was 9.68interventions per day. The interventions were for nutritional care (161 cases, 42.2%), followedby changes in administration route and dosage (94 cases, 24.6%), omission (59 cases, 15.5%),redundancy (40 cases, 10.4%), changes in medicine (15 cases, 3.9%), and side effects (13 cases, 3.4%). Conclusion: The conditions of patients admitted to ICU are typically unstable. Pharmacologicalinterventions suggested by a specialized pharmacist may help control the changing medicalcondition of patients in ICU. A higher participation of pharmacists specialized in working in aninterdisciplinary ICU team-based system could lead to safer treatments.