연구논문 - 고분자 : Methyl methacrylate 의 유화중합과 열분해에 관한 연구 (1) - 유화제의 영향 -

신은주,박찬헌,설수덕,김동건 ( Eun Ju Shin,Chan Hun Park,Soo Duk Seul,Dong Keun Kim ) 한국공업화학회 1993 한국공업화학회 연구논문 초록집 Vol.1990 No.3

감마 오리자놀의 위암세포증식억제 및 세포사멸 유도 효능

신은주(Eun Ju Shin),정상원(Sangwon Chung),황진택(Jin-Taek Hwang) 한국생물공학회 2017 KSBB Journal Vol.32 No.2

Gamma (γ)-oryzanol is a substance abundant in rice, which is widely cultivated in Asian countries. In this study, we evaluated the effect of γ-oryzanol treatment on proliferation and apoptosis of AGS human gastric carcinoma cells. AGS cells were treated with γ-oryzanol for 72 h in a dose dependent manner. Treatment of γ-oryzanol (50, 100, and 200 μg/mL) resulted in decreased AGS cell proliferation and increased number of cells in the sub-G1 population. Additionally, apoptotic cells were investigated by annexin V staining and mitochondrial membrane potential assays. Our results indicated that γ-oryzanol treatment increased the number of annexin V-positive cells and depolarized cells. This demonstrated that γ-oryzanol is effective for the induction of apoptosis in AGS cells. We next examined the expression of promising anticancer drug target molecules, including PTEN and HSP90. We found that treatment of γ-oryzanol induced the expression of PTEN in AGS cells. Under the same treatment conditions, γ-oryzanol reduced the expression of HSP90 in AGS cells. These results suggest that γ-oryzanol-induced apoptosis was accompanied by changes in regulation of PTEN and HSP90 in AGS cells. Taken together, γ-oryzanol could be used as a functional substance for the prevention of gastric cancer.

『 스키타이 차르 무덤, 아르잔-2호 』의 최신성과 및 학사적 의미

김재윤(Kim, Jae Youn) 부산고고학회 2021 고고광장 Vol.- No.28

본고에서는 시베리아 투바에서 발굴된 아르잔-2호에 대한 최신성과를 담아낸 추구노프와 파르칭거의 저서를소개하고 아르잔-2호 발굴의 학사적 의미를 살펴보고자 한다. 유라시아 초원의 대표적인 철기시대 문화인 스키토-시베리아 문화권의 기원지로 주목된 기원전 9세기 중반투바의 아르잔은 1호 발굴 이후 30년이 지나서야 에르미타주 박물관의 추구노프 박사와 독일 고고학연구소 팀의 공동연구로 인해서 2호가 발굴되었다. 기원전 7세기 중반으로 알려진 아르잔-2호는 하나의 호석 안에 26기의 무덤이 함께 축조되었고, 외부에서도제사 관련 시설 등이 있었던 것이 밝혀지면서 ’의례복합체‘라고 불린다. 아르잔-2호 내부에는 주인공의 무덤은이중으로 된 ’목실‘, 말 무덤, 석관묘, 퇴장지 등이 있었고, 4단계에 걸친 의례과정에서 각 무덤이 축조되었다는점이 밝혀졌다. 뿐만 아니라 금제품 유물이 다량으로 출토되었는데, 도굴당한 아르잔-1호와 기원전 6세기경부터 시작된 알타이 파지리크 문화에서는 금으로만 제작된 유물이 없기 때문에 금제 유물에 대한 인식의 변화도가져오게 되었다. 아르잔-2호보다 먼저 축조된 아르잔-1호는 지상에 매장중심부와 말 무덤을 방사상으로 나무를 연결해서 축조했으나, 이 유적에서는 지하에 각 무덤을 따로 축조해서 구조상에 큰 변화가 있었다는 점도 알 수 있게 되었다. 스키토-시베리아 문화권의 전성기인 피지리크 문화 중 가장 이른 바샤다르 유적보다 아르잔-2호에서 먼저 지하에 목실을 썼다는 점도 드러났다. 아르잔-2호의 5호묘에서 대량 발견된 금제품은 ‘시베리아 황금’의 실체를 접근 가능하게 했다. 특히 부조기법으로 만들어진 금제품은 기존의 흑해지역에서만 알려진 기법으로 제작된 것인데, 비슷한 시점에 시베리아에서도 출토된다는 점은 앞으로 금속가공과 관련해서도 많은 연구가 진척될 것으로 기대할 수 있다 Dr. Chugunov, the head of the excavation team of the Hermitage Museum Central Asia Excavation Team, released a book in 2017 that includes the structure and relics of Arzan-2, which were investigated with the German team for 5 years. The ruins provide clues to solve many of the areas that were not resolved after Arzan-1 in the mid-9th century BC, known as the origin of the Scythian culture. It was revealed that the burial main part, which was found in the phageric culture, the heyday of the Altai Scythian culture, which began in the 6th century BC, begins at the 5th tomb of Arzan-2. Not only that, among the four methods of making relics excavated from the ruins, the technology of making heavy gold, not gold leaf, by the relief method, was possessed not only in the Black Sea in the 7th century BC, but also in Tuva, Siberia during the same period. I think this is a part that needs to be progressed.

수소-메탄 혼합 가스의 연료 전환 제어 알고리즘에 관한 고찰

신은주(Eun Ju Shin),김영배(Young Bae Kim),정우현(Woohyun Jung) 한국에너지기후변화학회 2023 한국에너지기후변화학회 학술대회 Vol.2023 No.5

응급실에 내원한 국내 간질중첩증 소아의 발생율과 특성

신은주(Eun Ju Shin),황세희(Se Hee Hwang) 대한소아신경학회 2016 대한소아신경학회지 Vol.24 No.1

Purpose: Status epilepticus (SE) is the most common life-threatening neurological condition in childhood. To clarify the incidence and outcome, we have evaluated the epidemiological and clinical characteristics of SE patients in Korea. Methods: In evaluating data from the National Emergency Department Information System (NEDIS), we retrospectively analyzed patients, and classified them by age and sex distribution, body temperature, time on arrival, seasonal variation and treatment outcome. The patients were under 8 years old who visited 111 general hospital emergency rooms in Korea between 2007 and 2013. Results: There were 4,257 total patients enrolled in our study. The ratio of males to females was 1.11:1. The incidence of SE in Korean children was 14.5/100,000 in 2010, and the highest incidence was seen in patients 1 to 2 years old. We could not find a seasonal variation. Febrile patients with temperatures over 38 °C accounted for 1,901 patients(44.7%). Peak time on arrival was 6 p.m. to midnight for 1,301 patients (30.5%). 3,356 patients (78.8%) were admitted immediately for proper treatment, while 678 patients(15.9%) were allowed to go home after emergency treatment. Unfortunately, 4 patients (0.1%) died despite first aid. Conclusion: The most common age in SE is 1 to 2 years. Regarding the correlation of fever with SE, patients who exhibit fever accounted for almost half of the patients with SE. In our study, the mortality rate in emergency room was 0.1%. Therefore, anyone who is suspected to have SE should be immediately transferred to a general hospital with ICU facilities for intensive treatment under the direction of medical experts.

금융 사무원의 여가 참여에 따른 여가만족이 직무만족에 미치는 영향

신은주(Eun Ju Shin),조영득(Young Deuk Cho),조현철(Hyun Choul Cho) 한국여가레크리에이션학회 2015 한국여가레크리에이션학회지 Vol.39 No.2

The purpose of this study was to explore the effect of leisure satisfaction on job satisfaction according to leisure participation of financial workers. This study collected data from 300 financial workers who are working in Seoul, Chung cheongnam-do, Jeollabuk-do, Gyeongsangnam-do, and performed a final data analysis from 244 of those financial workers. SPSS 21.0 and Amos 21.0 were used to analyze the data. The results were as follows. First, leisure satisfaction showed a significant influence in leisure time and leisure expenses. In leisure activity, physical activity was found to have imported a much higher satisfaction compared to break leisure activities and recreational activities. Second, leisure activities were significant influence on job satisfaction. Third, sub-factor of leisure satisfaction on job satisfaction had a significant impact on leisure physical and mental and leisure environment satisfaction. Finally, to explore the relationship leisure participation, leisure satisfaction between job satisfaction of financial workers, path analysis was conducted. This study suggested the need for research on effective leisure activities that can help financial workers for job satisfaction.

미꾸리(Misgurnus anguillicaudatus)와 새코미꾸리 (Koreocobitis rotundicaudata) 개체군의 생태지표 특성 및 이·화학적 수질구배 분석

신은주 ( Eun Ju Shin ),최지웅 ( Ji Woong Choi ),안광국 ( Kwang Guk An ) 한국환경생물학회 2013 환경생물 : 환경생물학회지 Vol.31 No.4

본 연구에서는 미꾸리과 어류인 두 개체군(Ma, Kr)의 생태지표 특성 및 화학적 수질구배를 분석하였고 이를 근거로 기존의 내성도 분류의 타당성을 검토하였다. 각개체군의 화학적 특성에 따른 분포를 분석한 결과, 모든 수질변수에서 Kr-개체군이 좁은 분포 범위를 보였고 Ma-개체군이 넓은 분포 범위를 보여 Kr-개체군은 깨끗한 수환경을 선호하며 Ma-개체군은 악화된 수환경에 잘 적응하는 것으로 분석되었다. Ma-개체군은 공서어종 중 잡식종, 내성종이 우점하는 것으로 나타났지만, Kr-개체군은충식종, 민감종이 우점하는 것으로 나타났다. 서식지에 대한 생태적, 물리적 평가를 실시한 결과, Ma-개체군이 낮은 값을 나타내 Ma-개체군 분포지점이 비교적 생물학적 교란이 심하며 물리적 서식지가 악화되어 있는 것으로 나타났다. 이에 따라 Ma-개체군은 수생태계의 변화에 대한 적응력이 뛰어나며 Kr-개체군은 이러한 변화에 예민하게 반응하는 것으로 판단되어 기존 문헌의 내성도 분류가 타당하다는 것을 시사하였다. 본 연구에서 분석한각 개체군의 분포특성은 어류를 이용하여 수생태계를 평가하는데 있어 중요한 자료가 될 것으로 사료된다. The objectives of this research were to determine ecological characteristics and chemical gradients in two different loach populations-Misgurnus anguillicaudatus (Ma) and Koreocobitis rotundicaudata (Kr). Eight chemical parameters were compared to test the chemical preferences between the two species. The population of Kr occurred more in better water quality, compared to the Ma-population. The Ma-population co-occurred more with tolerant species (TS) and omnivores, whereas the Kr-population co-occurred more with sensitive species (SS) and insectivores. The differences in the tolerance and trophic composition matched well with the result of stream health assessment, based on the multi-metric model of Index of Biological Integrity (IBI). The IBI value in habitat with the Ma-population was “19.6” (range: 8~40) indicating a fair condition, and the IBI values of Kr-population was 29.4 (range: 12~40) indicating good condition. Similar results were found in physical habitat health analysis (QHEI). Overall, data analysis showed that the Mapopulation belong to the tolerant species and Kr-population belong to sensitive species in the tolerance classification.

심화영의 삶과 소리 : 대담자료 요약정리 및 음원 채록을 중심으로

신은주(Shin Eun ju) 국립국악원 2008 국악원논문집 Vol.18 No.-

본고는 심화영의 대담자료 정리를 기본 자료로 하여 충청 지역의 명인 심화영의 생애와판소리의 특성에 대해 정리한글이다. 심화영은 20세기 전반 충청지방의 판소리와 가야금병창 및 산조의 명인 심정순의 둘째 딸로, 부친의 음악 자산을 물려받았다. 광대의 딸이라는 이유로 주변의 천대를 감내해야했던 그녀는 스스로 기생을 길을 선택, 20세부터 33세까지 청진권번에서 기생으로 살았다. 그러다 해방 무렵 서산으로 돌아와 혼인한 이후에는 음악활동을 접고 평범한 아낙으로 지내다가, 구순이 거의 다 되어갈 무렵 세상에 나와 승무로 충청남도 무형문화재로 지정되었으며, 중고제 판소리를 보유한 마지막 인물로 평가받고 있다. 오랜 기간 음악 활동을 하지 않아 그녀의 음악적 수준은 그리 높지 않다. 그러나 다른 이에게 노래나 기악을 배운 경험이 없기에 오히려 순수한 충청지역 음악을 보유하고 있다고 할 수 있다. 때문에 그녀의 판소리는 심정순에게서 발견할 수 있는 충청 지역의 판소리특성이 그대로 남아 있다. 뿐만 아니라 판소리가 세련된 기교로 다듬어지고 정교해지지않은 덕에, 즉흥적인 요소 및 선율을 구사하는 기본 원리들에 의해서 이루어지고 있다고 하겠다. 이에 의하면 기본적인 호흡의 원리에 따라 선율이 구성되고 있고, 노래와 아니리(말로 하는 것)의 넘나듦이 자유로우며 처음과 끝을 힘 있게 분명히 함으로서 판소리를 완성시켜 나간다. 심화영의 판소리에서 발견한 이러한 원리 들은 비단 그녀의 판소리에서 뿐 아니라, 이를 토대로 좀 더 전문적으로 다듬어진 다른 창자들의 판소리에서도 적용될 수 있을 것이다. 그리고 기본 선율의 구성 원리에서 어떻게 점점 전문적인 판소리로 세련화 되어 가는지에 대해서도 언급할 수 있으리라 기대한다. Sim Whayeoung was born as the second daughter of Sim Jeongsun, a master in Pansori in Chungcheong region, Gayageum chorus and Sanjo in the early part of the 20th century, inheriting the musical asset of her father. She had to endure the cold reception from her neighbors since she was a daughter of a musician, chose the path to gisaeng(a singing and dancing girl) for herself, and lived such a life from when she was 20 years old till when she was 33 years old at Cheongjin area. However, she came back to Seosan around the liberation time, got married, stopped the musical activities and lived as a normal wife. When she nearly became 90 years old, she stepped out and was designated as an intangible cultural asset in seungmu(Buddhist dance). She has been evaluated as the last person who retained the Junggoje Pansori. Since she did not do a musical activity for a long time, her musical standard was not that high. Nevertheless, she had the purely Chungcheong region s music since she did not have any experience of learning songs or musical instrument from others. Subsequently, her Pansori exactly has the feature of Chungcheong region s Pansori which could be found in Sim Jung-Soon. In addition, since Pansori was not refined nor corrected in a refined technique, it can be said to have been made by fundamental principles which adopted an improvised element and melody. According to it, the melody is composed of in accordance with the basic principle of breath . The interchange of song and Aniri(Doing with words) is liberal. Pansori is completed by having a clear beginning and end. Such principles found in Sim Whayeoung s Pansori can be applied to her Pansori as well as other singers Pansori which was refined in a more professional manner. And it is expected to stipulate how a more professional Pansori is refined from a formation principle of basic melody.

사상체질에 따른 의사결정 및 학습 유형

신은주 ( Eun Ju Shin ) 대한한방신경정신과학회 2009 동의신경정신과학회지 Vol.20 No.4

Objectives: This study was performed to investigate the relationship between decision making style and learning style according to Sasang constitution. Methods: The subjects were 213 nursing students of K college in Jeonbuk, and the period of data gathering was limited from 1 Sep. 2009 to 7 Sep. 2009. The instrument tools included QSCC Ⅱ, decision making style, and learning style. The collected data were analyzed by SPSS-PC programme. Results: 1. Decision making style: Soeumin group had significantly high score in rational score compared with Soyangin(F=7.174 p=.001), and in dependent score compared with Taeumin and Soyangin (F=3.414, p=.035). 2. Learning style: Soyangin group had significantly high score in cooperation score compared with Taeumin(F=5.688 p=.004), and Taeumin group had significantly high score in emulous score compared with Soeumin and Soyangin (F=.148, p=.002). Conclusions: In conclusion, it was found that decision making style and learning style are significantly different according to Sasang constitution. Therefore, these results suggest that nursing educational program needs to be developed considering Sasang constitution.

빠르게 걷기 운동이 과체중 태음인 대학생의 피로, 혈중지질 및 신체조성에 미치는 효과

신은주(Shin Eun-Ju),김남초(Kim Nam-Cho) 한국성인간호학회 2008 성인간호학회지 Vol.20 No.4